Modulation of epigenetic regulators and cell fate decisions by miRNAs (Q38166839)

30 August 2017

title

Modulation of epigenetic regulators and cell fate decisions by miRNAs (English)

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30 August 2017

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30 August 2017

Andreas J Gruber

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30 August 2017

publication date

1 December 2013

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30 August 2017

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30 August 2017

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30 August 2017

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30 August 2017

page(s)

671-683

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TarBase 6.0: capturing the exponential growth of miRNA targets with experimental support

30 August 2017

cites work

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Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets

21 January 2018

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Analysis of CDS-located miRNA target sites suggests that they can effectively inhibit translation

21 January 2018

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Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans

21 January 2018

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The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

21 January 2018

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Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs

21 January 2018

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Ribosome profiling shows that miR-430 reduces translation before causing mRNA decay in zebrafish

21 January 2018

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miRNA-mediated gene silencing by translational repression followed by mRNA deadenylation and decay

21 January 2018

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Mutations that lead to reiterations in the cell lineages of C. elegans

21 January 2018

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Roles for microRNAs in conferring robustness to biological processes

21 January 2018

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miRNAs, cancer, and stem cell division

21 January 2018

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Cardiovascular epigenetics: from DNA methylation to microRNAs

21 January 2018

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Epigenetic regulation of miRNA genes and their role in human melanomas

21 January 2018

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MiRNAs, epigenetics, and cancer

21 January 2018

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Transcriptional and epigenetic regulation of human microRNAs

21 January 2018

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MicroRNA genes are transcribed by RNA polymerase II

21 January 2018

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The Microprocessor complex mediates the genesis of microRNAs

21 January 2018

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TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing

21 January 2018

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Posttranscriptional regulation of microRNA biogenesis in animals

21 January 2018

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miRNA repression of translation in vitro takes place during 43S ribosomal scanning.

21 January 2018

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PABP is not essential for microRNA-mediated translational repression and deadenylation in vitro

21 January 2018

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A molecular link between miRISCs and deadenylases provides new insight into the mechanism of gene silencing by microRNAs

21 January 2018

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Ago-TNRC6 triggers microRNA-mediated decay by promoting two deadenylation steps

21 January 2018

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Transcripts targeted by the microRNA-16 family cooperatively regulate cell cycle progression

21 January 2018

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Widespread changes in protein synthesis induced by microRNAs

21 January 2018

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The impact of microRNAs on protein output

21 January 2018

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Mammalian microRNAs predominantly act to decrease target mRNA levels

21 January 2018

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A biophysical miRNA-mRNA interaction model infers canonical and noncanonical targets

21 January 2018

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Most mammalian mRNAs are conserved targets of microRNAs

21 January 2018

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MicroRNAs: target recognition and regulatory functions

21 January 2018

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MicroRNA targets in Drosophila

21 January 2018

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Canalization of development by microRNAs

21 January 2018

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MicroRNAs and gene regulatory networks: managing the impact of noise in biological systems

21 January 2018

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Genome-wide survey of microRNA-transcription factor feed-forward regulatory circuits in human.

21 January 2018

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The role of incoherent microRNA-mediated feedforward loops in noise buffering

21 January 2018

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Chromatin structure, pluripotency and differentiation

21 January 2018

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Genome-wide occupancy analysis by ChIP-chip and ChIP-Seq

21 January 2018

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FAIRE (Formaldehyde-Assisted Isolation of Regulatory Elements) isolates active regulatory elements from human chromatin

21 January 2018

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Mapping accessible chromatin regions using Sono-Seq

21 January 2018

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Global mapping of protein-DNA interactions in vivo by digital genomic footprinting

21 January 2018

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High-resolution mapping and characterization of open chromatin across the genome

21 January 2018

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Dynamic regulation of nucleosome positioning in the human genome

21 January 2018

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The DNA-encoded nucleosome organization of a eukaryotic genome

21 January 2018

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Genome-wide kinetics of nucleosome turnover determined by metabolic labeling of histones

21 January 2018

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Regulation of chromatin by histone modifications

21 January 2018

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Structure and function of mammalian DNA methyltransferases.

21 January 2018

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CpG islands and the regulation of transcription

21 January 2018

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DNA methylation dynamics in health and disease

21 January 2018

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Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome

21 January 2018

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Genomic imprinting: intricacies of epigenetic regulation in clusters.

21 January 2018

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Chromosome-wide DNA methylation analysis predicts human tissue-specific X inactivation

21 January 2018

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Intronic CpG content and alternative splicing in human genes containing a single cassette exon

21 January 2018

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Chromatin and epigenetic regulation of pre-mRNA processing

21 January 2018

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Connections between chromatin signatures and splicing

21 January 2018

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Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription

21 January 2018

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DNA methylation and methyl-CpG binding proteins: developmental requirements and function

21 January 2018

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Molecular mechanisms mediating methylation-dependent silencing of ribosomal gene transcription

21 January 2018

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Cytosine methylation prevents binding to DNA of a HeLa cell transcription factor required for optimal expression of the adenovirus major late promoter

21 January 2018

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DNA methylation status predicts cell type-specific enhancer activity.

21 January 2018

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DNA methyltransferases and methyl-binding proteins of mammals

21 January 2018

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Structural basis for recognition of hemi-methylated DNA by the SRA domain of human UHRF1

21 January 2018

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The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA

21 January 2018

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Human DNA-(Cytosine-5) Methyltransferase-PCNA Complex as a Target for p21 WAF1

21 January 2018

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Limited up-regulation of DNA methyltransferase in human colon cancer reflecting increased cell proliferation.

21 January 2018

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Differential mRNA expression of the human DNA methyltransferases (DNMTs) 1, 3a and 3b during the G(0)/G(1) to S phase transition in normal and tumor cells

21 January 2018

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Stage- and cell-specific expression of Dnmt3a and Dnmt3b during embryogenesis.

21 January 2018

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DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

21 January 2018

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TETonic shift: biological roles of TET proteins in DNA demethylation and transcription

21 January 2018

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miR-148 targets human DNMT3b protein coding region

21 January 2018

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MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B

21 January 2018

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MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1.

21 January 2018

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Ten-eleven translocation (Tet) and thymine DNA glycosylase (TDG), components of the demethylation pathway, are direct targets of miRNA-29a

21 January 2018

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Regulation of somatic cell reprogramming through inducible mir-302 expression

21 January 2018

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MicroRNAs control de novo DNA methylation through regulation of transcriptional repressors in mouse embryonic stem cells

21 January 2018

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A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases

21 January 2018

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Occupying Chromatin: Polycomb Mechanisms for Getting to Genomic Targets, Stopping Transcriptional Traffic, and Staying Put

21 January 2018

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Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains

21 January 2018

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GC-rich sequence elements recruit PRC2 in mammalian ES cells

21 January 2018

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Control of developmental regulators by Polycomb in human embryonic stem cells

21 January 2018

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Genome-wide maps of chromatin state in pluripotent and lineage-committed cells

21 January 2018

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Whole-genome analysis of histone H3 lysine 4 and lysine 27 methylation in human embryonic stem cells

21 January 2018

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Whole-genome mapping of histone H3 Lys4 and 27 trimethylations reveals distinct genomic compartments in human embryonic stem cells

21 January 2018

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The Polycomb group protein EZH2 directly controls DNA methylation

21 January 2018

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A vertebrate Polycomb response element governs segmentation of the posterior hindbrain

21 January 2018

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A region of the human HOXD cluster that confers polycomb-group responsiveness

21 January 2018

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Modeling of epigenome dynamics identifies transcription factors that mediate Polycomb targeting

21 January 2018

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Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis

21 January 2018

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Long noncoding RNA as modular scaffold of histone modification complexes

21 January 2018

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Role of histone H3 lysine 27 methylation in X inactivation

21 January 2018

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Polycomb proteins targeted by a short repeat RNA to the mouse X chromosome

21 January 2018

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Role of histone H2A ubiquitination in Polycomb silencing

21 January 2018

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PCGF homologs, CBX proteins, and RYBP define functionally distinct PRC1 family complexes

21 January 2018

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RYBP-PRC1 complexes mediate H2A ubiquitylation at polycomb target sites independently of PRC2 and H3K27me3

21 January 2018

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Molecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4a

21 January 2018

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The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs

21 January 2018

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Targeting of the Bmi-1 oncogene/stem cell renewal factor by microRNA-128 inhibits glioma proliferation and self-renewal

21 January 2018

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MYC stimulates EZH2 expression by repression of its negative regulator miR-26a

21 January 2018

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Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer

21 January 2018

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The tumor suppressor microRNA-101 becomes an epigenetic player by targeting the polycomb group protein EZH2 in cancer

21 January 2018

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Cross talk between microRNA and epigenetic regulation in adult neurogenesis

21 January 2018

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Mir-214-dependent regulation of the polycomb protein Ezh2 in skeletal muscle and embryonic stem cells

21 January 2018

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A molecular roadmap of reprogramming somatic cells into iPS cells

21 January 2018

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SWI/SNF nucleosome remodellers and cancer.

21 January 2018

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Cell cycle arrest and repression of cyclin D1 transcription by INI1/hSNF5.

21 January 2018

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esBAF facilitates pluripotency by conditioning the genome for LIF/STAT3 signalling and by regulating polycomb function

21 January 2018

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Baf60c is essential for function of BAF chromatin remodelling complexes in heart development

21 January 2018

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An essential switch in subunit composition of a chromatin remodeling complex during neural development

21 January 2018

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An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency

21 January 2018

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An embryonic stem cell chromatin remodeling complex, esBAF, is an essential component of the core pluripotency transcriptional network.

21 January 2018

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Chromatin-Remodeling Components of the BAF Complex Facilitate Reprogramming

21 January 2018

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MirZ: an integrated microRNA expression atlas and target prediction resource

21 January 2018

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MicroRNAs miR-199a-5p and -3p Target the Brm Subunit of SWI/SNF to Generate a Double-Negative Feedback Loop in a Variety of Human Cancers

21 January 2018

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HATs and HDACs: from structure, function and regulation to novel strategies for therapy and prevention

21 January 2018

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Heterochromatin and epigenetic control of gene expression

21 January 2018

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Chromatin signatures of pluripotent cell lines

21 January 2018

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miR-449a targets HDAC-1 and induces growth arrest in prostate cancer

21 January 2018

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The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation

21 January 2018

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TGF-β Regulates miR-206 and miR-29 to Control Myogenic Differentiation through Regulation of HDAC4

21 January 2018

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MicroRNA-206 delays ALS progression and promotes regeneration of neuromuscular synapses in mice

21 January 2018

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Biological functions of miR-29b contribute to positive regulation of osteoblast differentiation

21 January 2018

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A mutation in the 3'-UTR of the HDAC6 gene abolishing the post-transcriptional regulation mediated by hsa-miR-433 is linked to a new form of dominant X-linked chondrodysplasia

21 January 2018

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Dicer is essential for mouse development

21 January 2018

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Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing

21 January 2018

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Characterization of Dicer-deficient murine embryonic stem cells.

21 January 2018

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DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal

21 January 2018

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Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells

21 January 2018

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Embryonic stem cell-specific MicroRNAs

21 January 2018

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Embryonic stem cell-specific microRNAs regulate the G1-S transition and promote rapid proliferation

21 January 2018

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Embryonic stem cell-specific microRNAs promote induced pluripotency

21 January 2018

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Highly Efficient miRNA-Mediated Reprogramming of Mouse and Human Somatic Cells to Pluripotency

21 January 2018

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MicroRNA-302 increases reprogramming efficiency via repression of NR2F2.

21 January 2018

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Multiple targets of miR-302 and miR-372 promote reprogramming of human fibroblasts to induced pluripotent stem cells

21 January 2018

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MicroRNA Cluster 302–367 Enhances Somatic Cell Reprogramming by Accelerating a Mesenchymal-to-Epithelial Transition

21 January 2018

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A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts

21 January 2018

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The cell cycle and Myc intersect with mechanisms that regulate pluripotency and reprogramming

21 January 2018

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Evolutionarily conserved multisubunit RBL2/p130 and E2F4 protein complex represses human cell cycle-dependent genes in quiescence

21 January 2018

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Regulation of DNA methyltransferase 1 by the pRb/E2F1 pathway

21 January 2018

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SWI/SNF Chromatin Remodeling Complex: A New Cofactor in Reprogramming

21 January 2018

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Opposing microRNA families regulate self-renewal in mouse embryonic stem cells

21 January 2018

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A mammalian microRNA expression atlas based on small RNA library sequencing

21 January 2018

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Lin28 mediates the terminal uridylation of let-7 precursor MicroRNA

21 January 2018

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A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment

21 January 2018

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Selective blockade of microRNA processing by Lin28

21 January 2018

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Impaired microRNA processing enhances cellular transformation and tumorigenesis

21 January 2018

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Identification of microRNAs regulating reprogramming factor LIN28 in embryonic stem cells and cancer cells.

21 January 2018

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MicroRNA-mediated conversion of human fibroblasts to neurons.

21 January 2018

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MicroRNA-124a is epigenetically regulated and acts as a tumor suppressor by controlling multiple targets in uveal melanoma.

21 January 2018

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Current Progress on Understanding MicroRNAs in Glioblastoma Multiforme

21 January 2018

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DBD--taxonomically broad transcription factor predictions: new content and functionality

21 January 2018

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AmiGO: online access to ontology and annotation data

21 January 2018

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MicroRNA Inhibition of Translation Initiation in Vitro by Targeting the Cap-Binding Complex eIF4F

21 January 2018

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21 January 2018

Identifiers

DOI

10.2217/EPI.13.65

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30 August 2017

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