Multidrug resistance: Physiological principles and nanomedical solutions. (Q38152179)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24120954%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

title

Multidrug resistance: Physiological principles and nanomedical solutions (English)

1 reference

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27 February 2020

main subject

multiple drug resistance

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24120954%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24120954%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24120954%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Gert Storm

1 reference

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27 February 2020

Fabian Kiessling

series ordinal

1 reference

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27 February 2020

language of work or name

English

0 references

publication date

10 October 2013

1 reference

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Advanced Drug Delivery Reviews

27 February 2020

published in

1 reference

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27 February 2020

volume

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24120954%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

issue

13-14

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27 February 2020

page(s)

1852-1865

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Enhanced antitumor efficacy by methotrexate conjugated Pluronic mixed micelles against KBv multidrug resistant cancer.

27 February 2020

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6 September 2017

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6 September 2017

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6 September 2017

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Active transport of imatinib into and out of cells: implications for drug resistance

6 September 2017

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Imatinib mesylate (STI571) is a substrate for the breast cancer resistance protein (BCRP)/ABCG2 drug pump

6 September 2017

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The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria.

6 September 2017

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6 September 2017

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The ABCG2 transporter is an efficient Hoechst 33342 efflux pump and is preferentially expressed by immature human hematopoietic progenitors

6 September 2017

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6 September 2017

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The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype

6 September 2017

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Expression of members of the multidrug resistance protein family in human term placenta

6 September 2017

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Camptothecin resistance: role of the ATP-binding cassette (ABC), mitoxantrone-resistance half-transporter (MXR), and potential for glucuronidation in MXR-expressing cells

6 September 2017

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Characterization of a leukotriene C4 export mechanism in human platelets: possible involvement of multidrug resistance-associated protein 1

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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The human multidrug resistance-associated protein MRP is a plasma membrane drug-efflux pump

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells.

6 September 2017

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Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues

6 September 2017

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Structural model of ATP-binding proteins associated with cystic fibrosis, multidrug resistance and bacterial transport

6 September 2017

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Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line

6 September 2017

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A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants

6 September 2017

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Expression of ATP-binding cassette membrane transporters in rodent and human sertoli cells: relevance to the permeability of antiretroviral therapy at the blood-testis barrier

6 September 2017

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Overcoming cellular multidrug resistance using classical nanomedicine formulations

6 September 2017

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Reversal of multidrug resistance by co-delivery of tariquidar (XR9576) and paclitaxel using long-circulating liposomes.

6 September 2017

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Function of MRP1/ABCC1 is not dependent on cholesterol or cholesterol-stabilized lipid rafts

6 September 2017

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Doxorubicin loaded iron oxide nanoparticles overcome multidrug resistance in cancer in vitro

6 September 2017

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Ixabepilone, a novel microtubule-targeting agent for breast cancer, is a substrate for P-glycoprotein (P-gp/MDR1/ABCB1) but not breast cancer resistance protein (BCRP/ABCG2).

14 September 2017

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Knockdown of caveolin-1 decreases activity of breast cancer resistance protein (BCRP/ABCG2) and increases chemotherapeutic sensitivity

14 September 2017

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Development of PLGA Nanoparticles Simultaneously Loaded with Vincristine and Verapamil for Treatment of Hepatocellular Carcinoma

14 September 2017

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14 September 2017

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Dual-targeting topotecan liposomes modified with tamoxifen and wheat germ agglutinin significantly improve drug transport across the blood-brain barrier and survival of brain tumor-bearing animals

14 September 2017

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Nanoparticle-mediated simultaneous and targeted delivery of paclitaxel and tariquidar overcomes tumor drug resistance

14 September 2017

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Localization of the human breast cancer resistance protein (BCRP/ABCG2) in lipid rafts/caveolae and modulation of its activity by cholesterol in vitro

14 September 2017

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Simultaneous delivery of doxorubicin and GG918 (Elacridar) by new polymer-lipid hybrid nanoparticles (PLN) for enhanced treatment of multidrug-resistant breast cancer

14 September 2017

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In vitro cytotoxicity of Stealth liposomes co-encapsulating doxorubicin and verapamil on doxorubicin-resistant tumor cells.

14 September 2017

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Role of the N-terminal transmembrane region of the multidrug resistance protein MRP2 in routing to the apical membrane in MDCKII cells

14 September 2017

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Methotrexate cross-resistance in a mitoxantrone-selected multidrug-resistant MCF7 breast cancer cell line is attributable to enhanced energy-dependent drug efflux

28 September 2017

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Export pumps for anionic conjugates encoded by MRP genes.

28 September 2017

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ATP- and glutathione-dependent transport of chemotherapeutic drugs by the multidrug resistance protein MRP1.

28 September 2017

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Multiplicity of biliary excretion mechanisms for the camptothecin derivative irinotecan (CPT-11), its metabolite SN-38, and its glucuronide: role of canalicular multispecific organic anion transporter and P-glycoprotein

28 September 2017

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Involvement of P-glycoprotein in the transmembrane transport of interleukin-2 (IL-2), IL-4, and interferon-gamma in normal human T lymphocytes.

28 September 2017

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Polarized transport of docetaxel and vinblastine mediated by P-glycoprotein in human intestinal epithelial cell monolayers

28 September 2017

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Time-resolved Fourier transform infrared spectroscopy of the nucleotide-binding domain from the ATP-binding Cassette transporter MsbA: ATP hydrolysis is the rate-limiting step in the catalytic cycle

28 September 2017

1 reference

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P-glycoprotein inhibition by membrane cholesterol modulation

23 June 2018

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Purification and 3D structural analysis of oligomeric human multidrug transporter ABCG2.

23 June 2018

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The distribution of drug-efflux pumps, P-gp, BCRP, MRP1 and MRP2, in the normal blood-testis barrier and in primary testicular tumours.

23 June 2018

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Transport of methotrexate (MTX) and folates by multidrug resistance protein (MRP) 3 and MRP1: effect of polyglutamylation on MTX transport.

23 June 2018

1 reference

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The human multidrug resistance protein MRP1 translocates sphingolipid analogs across the plasma membrane

23 June 2018

1 reference

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Multidrug resistance protein-mediated transport of chlorambucil and melphalan conjugated to glutathione

23 June 2018

1 reference

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ATP-dependent transport of bilirubin glucuronides by the multidrug resistance protein MRP1 and its hepatocyte canalicular isoform MRP2

23 June 2018

1 reference

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Membrane topology and glycosylation of the human multidrug resistance-associated protein

23 June 2018

1 reference

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Fluorescent cellular indicators are extruded by the multidrug resistance protein.

23 June 2018

1 reference

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The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates.

23 June 2018

1 reference

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ATP-dependent transport of glutathione S-conjugates by the multidrug resistance-associated protein.

23 June 2018

1 reference

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Reduced permeability in CHO cells as a mechanism of resistance to colchicine

23 June 2018

1 reference

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Increased drug permeability in Chinese hamster ovary cells in the presence of cyanide.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939439

Verapamil reversal of doxorubicin resistance in multidrug-resistant human myeloma cells and association with drug accumulation and DNA damage.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939439

Characterization of the ATPase activity of the Mr 170,000 to 180,000 membrane glycoprotein (P-glycoprotein) associated with multidrug resistance in K562/ADM cells

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939439

Pharmacological and biological evidence for differing mechanisms of doxorubicin resistance in two human tumor cell lines

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939439

Detection of P-glycoprotein in ovarian cancer: a molecular marker associated with multidrug resistance.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939439

Characterization of adriamycin-resistant human breast cancer cells which display overexpression of a novel resistance-related membrane protein

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939439

Pharmacokinetics of intravenously administered stealth liposomal doxorubicin modulated with verapamil in rats

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939439

MDR1 P-gp expression and activity in intact human placental tissue; upregulation by retroviral transduction

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939439

Localization of breast cancer resistance protein (BCRP) in microvessel endothelium of human control and epileptic brain

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939439

Mutation of proline residues in the NH(2)-terminal region of the multidrug resistance protein, MRP1 (ABCC1): effects on protein expression, membrane localization, and transport function

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939439

Transport of methotrexate, methotrexate polyglutamates, and 17beta-estradiol 17-(beta-D-glucuronide) by ABCG2: effects of acquired mutations at R482 on methotrexate transport.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939439

MRP1-transfected cells do not show increased resistance against oxidative stress.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939439

Expression of ATP-binding cassette transporter in human salivary ducts.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939439

Expression and functional activity of the ABC-transporter proteins P-glycoprotein and multidrug-resistance protein 1 in human brain tumor cells and astrocytes

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939439

Subcellular localization and distribution of the breast cancer resistance protein transporter in normal human tissues.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939439

Reversion of multidrug resistance by co-encapsulation of doxorubicin and cyclosporin A in polyalkylcyanoacrylate nanoparticles.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939439

ATP-dependent glutathione disulphide transport mediated by the MRP gene-encoded conjugate export pump

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939439

Detection of P-glycoprotein with four monoclonal antibodies in normal and tumor tissues.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3939439

Antiestrogens and steroid hormones: substrates of the human P-glycoprotein.

31 August 2018

1 reference

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Transport properties of the multidrug resistance-associated protein (MRP) in human tumour cells

31 August 2018

1 reference

12 December 2020

Reversal of multidrug resistance by transferrin-conjugated liposomes co-encapsulating doxorubicin and verapamil

1 reference

12 December 2020

Identification of the multidrug-resistance protein (MRP) as the glutathione-S-conjugate export pump of erythrocytes

1 reference

12 December 2020

Transport of glutathione, glucuronate, and sulfate conjugates by the MRP gene-encoded conjugate export pump

1 reference

12 December 2020

Transbilayer movement of NBD-labeled phospholipids in red blood cell membranes: outward-directed transport by the multidrug resistance protein 1 (MRP1)

1 reference

12 December 2020

Transport of phosphatidylcholine in MDR3-negative epithelial cell lines via drug-induced MDR1 P-glycoprotein

1 reference

12 December 2020

Efficiency of P‐glycoprotein–Mediated Exclusion of Rhodamine Dyes from Multidrug‐Resistant Cells is Determined by their Passive Transmembrane Movement Rate

1 reference

12 December 2020

ABCG2 is a high-capacity urate transporter and its genetic impairment increases serum uric acid levels in humans

1 reference

12 December 2020

Increased sensitivity to anticancer drugs and decreased inflammatory response in mice lacking the multidrug resistance-associated protein

1 reference

12 December 2020

Multidrug-resistance phenotype of a subpopulation of T-lymphocytes without drug selection

1 reference

12 December 2020

The plasma membrane polarity of human biliary epithelial cells: in situ immunohistochemical analysis and functional implications

1 reference

12 December 2020

Traceable Multifunctional Micellar Nanocarriers for Cancer-Targeted Co-delivery of MDR-1 siRNA and Doxorubicin

1 reference

12 December 2020

Eighth International Nanomedicine and Drug Delivery Symposium (NanoDDS'10)

1 reference

12 December 2020

Active efflux of the free acid form of the fluorescent dye 2',7'-bis(2-carboxyethyl)-5(6)-carboxyfluorescein in multidrug-resistance-protein-overexpressing murine and human leukemia cells

1 reference

12 December 2020

10.1016/J.ADDR.2013.09.018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24120954%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24120954%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

PubMed publication ID

24120954

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24120954%20AND%20SRC:MED&resulttype=core&format=json