A Central role for mTOR in lipid homeostasis (Q38131225)

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scientific article published on 22 August 2013

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Language	Label	Description	Also known as
English	A Central role for mTOR in lipid homeostasis	scientific article published on 22 August 2013

Statements

instance of

scholarly article

1 reference

stated in

Europe PubMed Central

PMC publication ID

3818790

retrieved

29 August 2017

review article

3 references

stated in

PubMed

retrieved

28 September 2019

stated in

PubMed

retrieved

18 December 2020

stated in

PubMed

retrieved

28 January 2021

title

A Central role for mTOR in lipid homeostasis (English)

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stated in

Europe PubMed Central

PMC publication ID

3818790

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29 August 2017

main subject

enzyme

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PubMed

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28 September 2019

lipid metabolism

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PubMed

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18 December 2020

serine/threonine-protein kinase TOR

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PubMed

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28 January 2021

author

David M. Sabatini

series ordinal

2

object named as

David M Sabatini

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Europe PubMed Central

PMC publication ID

3818790

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29 August 2017

author name string

Dudley W Lamming

series ordinal

1

1 reference

stated in

Europe PubMed Central

PMC publication ID

3818790

retrieved

29 August 2017

publication date

22 August 2013

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stated in

Europe PubMed Central

PMC publication ID

3818790

retrieved

29 August 2017

1 October 2013

3 references

stated in

PubMed Central

retrieved

28 September 2019

stated in

PubMed Central

retrieved

18 December 2020

stated in

PubMed Central

retrieved

28 January 2021

published in

Cell Metabolism

4 references

stated in

Europe PubMed Central

PMC publication ID

3818790

retrieved

29 August 2017

stated in

PubMed Central

retrieved

28 September 2019

stated in

PubMed Central

retrieved

18 December 2020

stated in

PubMed Central

retrieved

28 January 2021

volume

18

1 reference

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Europe PubMed Central

PMC publication ID

3818790

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29 August 2017

issue

4

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Europe PubMed Central

PMC publication ID

3818790

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29 August 2017

page(s)

465-469

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Europe PubMed Central

PMC publication ID

3818790

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29 August 2017

cites work

Rapalogs and mTOR inhibitors as anti-aging therapeutics

1 reference

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PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3818790

retrieved

6 September 2017

BSTA promotes mTORC2-mediated phosphorylation of Akt1 to suppress expression of FoxC2 and stimulate adipocyte differentiation

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3818790

retrieved

6 September 2017

Rapamycin has a biphasic effect on insulin sensitivity in C2C12 myotubes due to sequential disruption of mTORC1 and mTORC2.

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3818790

retrieved

6 September 2017

Insulin stimulation of SREBP-1c processing in transgenic rat hepatocytes requires p70 S6-kinase

1 reference

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PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3818790

retrieved

6 September 2017

DEPTOR cell-autonomously promotes adipogenesis, and its expression is associated with obesity.

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3818790

retrieved

6 September 2017

Identification of Akt-independent regulation of hepatic lipogenesis by mammalian target of rapamycin (mTOR) complex 2

1 reference

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PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3818790

retrieved

6 September 2017

Hepatic mTORC2 activates glycolysis and lipogenesis through Akt, glucokinase, and SREBP1c

1 reference

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PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3818790

retrieved

6 September 2017

mTOR signaling in growth control and disease

1 reference

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3818790

retrieved

6 September 2017

Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity

1 reference

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PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3818790

retrieved

6 September 2017

S6 kinase 2 deficiency enhances ketone body production and increases peroxisome proliferator-activated receptor alpha activity in the liver

1 reference

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PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3818790

retrieved

6 September 2017

mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3818790

retrieved

6 September 2017

Akt stimulates hepatic SREBP1c and lipogenesis through parallel mTORC1-dependent and independent pathways

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3818790

retrieved

6 September 2017

Activation of a metabolic gene regulatory network downstream of mTOR complex 1

1 reference

stated in

PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3818790

retrieved

6 September 2017

S6K1 plays a critical role in early adipocyte differentiation

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3818790

retrieved

6 September 2017

Fat cell-specific ablation of rictor in mice impairs insulin-regulated fat cell and whole-body glucose and lipid metabolism

1 reference

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PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3818790

retrieved

6 September 2017

Insulin stimulates adipogenesis through the Akt-TSC2-mTORC1 pathway

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3818790

retrieved

6 September 2017

mTOR complex 2 in adipose tissue negatively controls whole-body growth

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3818790

retrieved

6 September 2017

DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3818790

retrieved

6 September 2017

Rictor/TORC2 regulates Caenorhabditis elegans fat storage, body size, and development through sgk-1

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3818790

retrieved

6 September 2017

Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3818790

retrieved

6 September 2017

Skeletal muscle-specific ablation of raptor, but not of rictor, causes metabolic changes and results in muscle dystrophy

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3818790

retrieved

6 September 2017

SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3818790

retrieved

6 September 2017

Muscle-specific deletion of rictor impairs insulin-stimulated glucose transport and enhances Basal glycogen synthase activity

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3818790

retrieved

6 September 2017

mTORC1 controls fasting-induced ketogenesis and its modulation by ageing.

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3818790

retrieved

14 September 2017

Adipose-specific knockout of raptor results in lean mice with enhanced mitochondrial respiration

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3818790

retrieved

23 June 2018

Identifiers

DOI

10.1016/J.CMET.2013.08.002

1 reference

stated in

Europe PubMed Central

PMC publication ID

3818790

retrieved

29 August 2017

PMC publication ID

3818790

1 reference

stated in

Europe PubMed Central

PMC publication ID

3818790

retrieved

29 August 2017

PubMed publication ID

23973332

1 reference

stated in

Europe PubMed Central

PMC publication ID

3818790

retrieved

29 August 2017

ResearchGate publication ID

256099727

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