IL-17 targeted therapies for psoriasis (Q38111443)

29 August 2017

title

IL-17 targeted therapies for psoriasis (English)

1 reference

29 August 2017

Andrea Chiricozzi

1 reference

29 August 2017

James G Krueger

series ordinal

1 reference

29 August 2017

language of work or name

English

0 references

publication date

3 June 2013

1 reference

Expert Opinion on Investigational Drugs

29 August 2017

published in

1 reference

29 August 2017

1 reference

29 August 2017

1 reference

29 August 2017

page(s)

993-1005

1 reference

Epidemiology of psoriasis. Review and the German perspective

29 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

Psoriasis and systemic inflammatory diseases: potential mechanistic links between skin disease and co-morbid conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

Psoriasis patients show signs of insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

Disease concomitance in psoriasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

Psoriasis and occlusive vascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

Psoriasis and risk of nonfatal cardiovascular disease in U.S. women: a cohort study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

An Italian study on psoriasis and depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

Psoriasis causes as much disability as other major medical diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

Health economics and the modern management of psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

Experiences of stigmatization play a role in mediating the impact of disease severity on quality of life in psoriasis patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

A human interleukin-12/23 monoclonal antibody for the treatment of psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

Interleukin-17 and type 17 helper T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

The IL-17 cytokine family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

IL-17-producing CD8+ T lymphocytes from psoriasis skin plaques are cytotoxic effector cells that secrete Th17-related cytokines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

Identification of a novel proinflammatory human skin-homing Vγ9Vδ2 T cell subset with a potential role in psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

Mast cells and neutrophils release IL-17 through extracellular trap formation in psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

Recent advances in the IL-17 cytokine family

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

Structure and signalling in the IL-17 receptor family

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

IL-17s adopt a cystine knot fold: structure and activity of a novel cytokine, IL-17F, and implications for receptor binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

Interleukin-17 family and IL-17 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

New IL-17 family members promote Th1 or Th2 responses in the lung: in vivo function of the novel cytokine IL-25

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

Transgenic overexpression of human IL-17E results in eosinophilia, B-lymphocyte hyperplasia, and altered antibody production

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

Interleukin-17/interleukin-17 receptor-mediated signaling is important for generation of an optimal polymorphonuclear response against Toxoplasma gondii infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

Requirement of interleukin 17 receptor signaling for lung CXC chemokine and granulocyte colony-stimulating factor expression, neutrophil recruitment, and host defense

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

Requirement of interleukin-17A for systemic anti-Candida albicans host defense in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

Cutting edge: roles of Toll-like receptor 4 and IL-23 in IL-17 expression in response to Klebsiella pneumoniae infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

Anti-IL-17A therapy protects against bone erosion in experimental models of rheumatoid arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

Pathogenesis and therapy of psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

IL-17A is essential for cell activation and inflammatory gene circuits in subjects with psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

IL-23 induces human osteoclastogenesis via IL-17 in vitro, and anti-IL-23 antibody attenuates collagen-induced arthritis in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

CD8(+) T cells in the lesional skin of atopic dermatitis and psoriasis patients are an important source of IFN-γ, IL-13, IL-17, and IL-22.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

The immunologic basis for the treatment of psoriasis with new biologic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

Resident skin cells in psoriasis: a special look at the pathogenetic functions of keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

The cytokine and chemokine network in psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

Increase in TNF-alpha and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a)

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

Resident and "inflammatory" dendritic cells in human skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

Characterization of dermal dendritic cells in psoriasis. Autostimulation of T lymphocytes and induction of Th1 type cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

Integrative responses to IL-17 and TNF-α in human keratinocytes account for key inflammatory pathogenic circuits in psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

Overexpression of vascular permeability factor/vascular endothelial growth factor and its receptors in psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

Induction and effector functions of T(H)17 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

IL-21 and TGF-beta are required for differentiation of human T(H)17 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from T(H)-17, T(H)1 and T(H)2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

IL-23 drives pathogenic IL-17-producing CD8+ T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

A Th17-like developmental process leads to CD8(+) Tc17 cells with reduced cytotoxic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

Pivotal role of dermal IL-17-producing γδ T cells in skin inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

Psoriasis is characterized by accumulation of immunostimulatory and Th1/Th17 cell-polarizing myeloid dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

Overrepresentation of IL-17A and IL-22 Producing CD8 T Cells in Lesional Skin Suggests Their Involvement in the Pathogenesis of Psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

Polymorphisms of the IL12B and IL23R genes are associated with psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

Common variants at TRAF3IP2 are associated with susceptibility to psoriatic arthritis and psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

Psoriasis is associated with increased beta-defensin genomic copy number

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

The emerging role of IL-17 in the pathogenesis of psoriasis: preclinical and clinical findings

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2-dependent mechanisms with implications for psoriasis pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

In vitro and in situ expression of IL-23 by keratinocytes in healthy skin and psoriasis lesions: enhanced expression in psoriatic skin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

Increased expression of interleukin 23 p19 and p40 in lesional skin of patients with psoriasis vulgaris

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

Effective treatment of psoriasis with etanercept is linked to suppression of IL-17 signaling, not immediate response TNF genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

Effective narrow-band UVB radiation therapy suppresses the IL-23/IL-17 axis in normalized psoriasis plaques

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

Amelioration of epidermal hyperplasia by TNF inhibition is associated with reduced Th17 responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

Up-regulation of macrophage inflammatory protein-3 alpha/CCL20 and CC chemokine receptor 6 in psoriasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

Effects of AIN457, a Fully Human Antibody to Interleukin-17A, on Psoriasis, Rheumatoid Arthritis, and Uveitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

Emerging role of IL-17 in atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

The risk of mortality in patients with psoriasis: results from a population-based study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

European S3-Guidelines on the systemic treatment of psoriasis vulgaris

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

Anti–Interleukin-17 Monoclonal Antibody Ixekizumab in Chronic Plaque Psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

Brodalumab, an Anti–Interleukin-17–Receptor Antibody for Psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2013.806483

10.1517/13543784.2013.806483

21 January 2018

Identifiers

DOI

1 reference

29 August 2017

1 reference