Design and development of reactive injectable and settable polymeric biomaterials (Q38105523)

28 August 2017

title

Design and development of reactive injectable and settable polymeric biomaterials (English)

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28 August 2017

Scott A Guelcher

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28 August 2017

Jonathan M Page

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28 August 2017

Andrew J Harmata

series ordinal

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28 August 2017

publication date

10 May 2013

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Journal of Biomedical Materials Research Part A

28 August 2017

published in

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28 August 2017

volume

101

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28 August 2017

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28 August 2017

page(s)

3630-3645

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Biomaterials: where we have been and where we are going

28 August 2017

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Biodegradable polyurethanes: synthesis and applications in regenerative medicine

21 January 2018

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Enzyme-catalyzed crosslinkable hydrogels: emerging strategies for tissue engineering

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Predicting clinical biological responses to dental materials

21 January 2018

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From vulcanite to vinyl, a history of resins in restorative dentistry.

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Infection of orthopedic implants and the use of antibiotic-loaded bone cements. A review

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Implant infections: a haven for opportunistic bacteria

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A review of risk factors for catheter-related bloodstream infection caused by percutaneously inserted, noncuffed central venous catheters: implications for preventive strategies

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Ethylene oxide sterilization of medical devices: a review

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Local delivery of tobramycin from injectable biodegradable polyurethane scaffolds

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Prolonged local antibiotics delivery from hydroxyapatite functionalised with cyclodextrin polymers.

21 January 2018

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Sustained release of vancomycin from polyurethane scaffolds inhibits infection of bone wounds in a rat femoral segmental defect model

21 January 2018

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Antibiotic-releasing porous polymethylmethacrylate/gelatin/antibiotic constructs for craniofacial tissue engineering.

21 January 2018

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Dual delivery of an antibiotic and a growth factor addresses both the microbiological and biological challenges of contaminated bone fractures

21 January 2018

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The use of BMP-2 coupled - Nanosilver-PLGA composite grafts to induce bone repair in grossly infected segmental defects

21 January 2018

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Increasing vascularity to improve healing of a segmental defect of the rat femur.

21 January 2018

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Medical device development: the challenge for ergonomics.

21 January 2018

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Rheological properties of concentrated aqueous injectable calcium phosphate cement slurry

21 January 2018

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Biocompatibility and chemical reaction kinetics of injectable, settable polyurethane/allograft bone biocomposites

21 January 2018

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Viscoelastic characterization and modeling of gelation kinetics of injectable in situ cross-linkable poly(lactide-co-ethylene oxide-co-fumarate) hydrogels

21 January 2018

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Operating time and survival of primary total hip replacements: an analysis of 31,745 primary cemented and uncemented total hip replacements from local hospitals reported to the Norwegian Arthroplasty Register 1987-2001.

21 January 2018

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A pictorial classification atlas of cement extravasation with vertebral augmentation

21 January 2018

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Biomaterials in tissue engineering

21 January 2018

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https://api.crossref.org/works/10.1002%2FJBM.A.34665

Mechanisms of polymer degradation and erosion

21 January 2018

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https://api.crossref.org/works/10.1002%2FJBM.A.34665

Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering.

21 January 2018

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https://api.crossref.org/works/10.1002%2FJBM.A.34665

The cyanoacrylate topical skin adhesives.

21 January 2018

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https://api.crossref.org/works/10.1002%2FJBM.A.34665

US FDA perspective on the regulations of medical-grade polymers: cyanoacrylate polymer medical device tissue adhesives

21 January 2018

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https://api.crossref.org/works/10.1002%2FJBM.A.34665

Cyanoacrylates for skin closure

21 January 2018

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https://api.crossref.org/works/10.1002%2FJBM.A.34665

A standardized injection technique and regimen ensures success and safety of N-butyl-2-cyanoacrylate injection for the treatment of gastric fundal varices (with videos).

21 January 2018

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https://api.crossref.org/works/10.1002%2FJBM.A.34665

2-Octyl-cyanoacrylate (Dermabond), a new glue for variceal injection therapy: results of a preliminary animal study

21 January 2018

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https://api.crossref.org/works/10.1002%2FJBM.A.34665

Photopolymerization of biomaterials: issues and potentialities in drug delivery, tissue engineering, and cell encapsulation applications

21 January 2018

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https://api.crossref.org/works/10.1002%2FJBM.A.34665

Review: photopolymerizable and degradable biomaterials for tissue engineering applications

21 January 2018

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https://api.crossref.org/works/10.1002%2FJBM.A.34665

Photopolymerizable hydrogels for tissue engineering applications

21 January 2018

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https://api.crossref.org/works/10.1002%2FJBM.A.34665

A review of photocrosslinked polyanhydrides: in situ forming degradable networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Efficacy and biocompatibility of a photopolymerized, synthetic, absorbable hydrogel as a dural sealant in a canine craniotomy model

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Evaluation of polyethylene glycol based hydrogel for tissue sealing after laparoscopic partial nephrectomy in a porcine model

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Transdermal photopolymerization for minimally invasive implantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Photoinitiated polymerization of PEG-diacrylate with lithium phenyl-2,4,6-trimethylbenzoylphosphinate: polymerization rate and cytocompatibility

21 January 2018

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https://api.crossref.org/works/10.1002%2FJBM.A.34665

Structure-toxicity relationships of acrylic monomers

21 January 2018

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https://api.crossref.org/works/10.1002%2FJBM.A.34665

Ethyl acrylate-induced gastric toxicity. II. Structure-toxicity relationships and mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Application of structure-activity relationships to investigate the molecular mechanisms of hepatocyte toxicity and electrophilic reactivity of alpha,beta-unsaturated aldehydes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Glutathione depletion in rat hepatocytes: a mixture toxicity study with alpha, beta-unsaturated esters

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Injectable matrices and scaffolds for drug delivery in tissue engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Injectable biomaterials for regenerating complex craniofacial tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Variable cytocompatibility of six cell lines with photoinitiators used for polymerizing hydrogels and cell encapsulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Injectable hydrogels for central nervous system therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Material properties and cytocompatibility of injectable MMP degradable poly(lactide ethylene oxide fumarate) hydrogel as a carrier for marrow stromal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Photopolymerizable and injectable polyurethanes for biomedical applications: synthesis and biocompatibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Reduction of fibrinogen adsorption on PEG-coated polystyrene surfaces

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Photoencapsulation of osteoblasts in injectable RGD-modified PEG hydrogels for bone tissue engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Photocurable surgical tissue adhesive glues composed of photoreactive gelatin and poly(ethylene glycol) diacrylate

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Promoting nerve cell functions on hydrogels grafted with poly(L-lysine).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Hydrogels as extracellular matrix mimics for 3D cell culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

PEG-based hydrogels as an in vitro encapsulation platform for testing controlled beta-cell microenvironments

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Assessment of hepatocellular function within PEG hydrogels

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Fabrication of 3D hepatic tissues by additive photopatterning of cellular hydrogels

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Injectable biodegradable hydrogels for embryonic stem cell transplantation: improved cardiac remodelling and function of myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Incorporation of tissue-specific molecules alters chondrocyte metabolism and gene expression in photocrosslinked hydrogels

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Encapsulating chondrocytes in degrading PEG hydrogels with high modulus: engineering gel structural changes to facilitate cartilaginous tissue production

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Development of porous PEG hydrogels that enable efficient, uniform cell-seeding and permit early neural process extension

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Injectable biodegradable hydrogel composites for rabbit marrow mesenchymal stem cell and growth factor delivery for cartilage tissue engineering.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Photopolymerized poly(ethylene glycol)/poly(L-lysine) hydrogels for the delivery of neural progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Thermoresponsive, in situ cross-linkable hydrogels based on N-isopropylacrylamide: fabrication, characterization and mesenchymal stem cell encapsulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

The enhancement of chondrogenic differentiation of human mesenchymal stem cells by enzymatically regulated RGD functionalities

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Respiratory effects of inhaled isocyanates

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Synthesis, mechanical properties, biocompatibility, and biodegradation of polyurethane networks from lysine polyisocyanates

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Toluene diisocyanate (TDI) pulmonary disease: Immunologic and inhalation challenge studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Carcinogenic risk of toluene diisocyanate and 4,4'-methylenediphenyl diisocyanate: epidemiological and experimental evidence

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Toxicity and biodegradation of diamines

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Toxic hydrolysis product from a biodegradable foam implant

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Synthesis and characterization of an injectable allograft bone/polymer composite bone void filler with tunable mechanical properties.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Synthesis, in vitro degradation, and mechanical properties of two-component poly(ester urethane)urea scaffolds: effects of water and polyol composition

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Synthesis and in vitro biocompatibility of injectable polyurethane foam scaffolds

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Injectable biodegradable polyurethane scaffolds with release of platelet-derived growth factor for tissue repair and regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

A new peptide-based urethane polymer: synthesis, biodegradation, and potential to support cell growth in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Synthesis, biodegradability, and biocompatibility of lysine diisocyanate-glucose polymers

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Lysine-derived urethane surgical adhesive prevents seroma formation in a canine abdominoplasty model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Randomized, prospective study of TissuGlu® surgical adhesive in the management of wound drainage following abdominoplasty

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Injectable polyurethane composite scaffolds delay wound contraction and support cellular infiltration and remodeling in rat excisional wounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Characterization of the degradation mechanisms of lysine-derived aliphatic poly(ester urethane) scaffolds

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Sustained local delivery of siRNA from an injectable scaffold

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Synthesis, characterization, and remodeling of weight-bearing allograft bone/polyurethane composites in the rabbit.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Biodegradable injectable polyurethanes: synthesis and evaluation for orthopaedic applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Synthesis, characterization of calcium phosphates/polyurethane composites for weight-bearing implants

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Injectable reactive biocomposites for bone healing in critical-size rabbit calvarial defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Sequential click reactions for synthesizing and patterning three-dimensional cell microenvironments

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Marrying click chemistry with polymerization: expanding the scope of polymeric materials

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Thiol-ene click chemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Novel hydrogels via click chemistry: synthesis and potential biomedical applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Cellular consequences of copper complexes used to catalyze bioorthogonal click reactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Cytocompatible poly(ethylene glycol)-co-polycarbonate hydrogels cross-linked by copper-free, strain-promoted click chemistry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Peptide-Functionalized Click Hydrogels with Independently Tunable Mechanics and Chemical Functionality for 3D Cell Culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Thiol-ene “click” reactions and recent applications in polymer and materials synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Systematic modulation of Michael-type reactivity of thiols through the use of charged amino acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Synthesis and evaluation of injectable, in situ crosslinkable synthetic extracellular matrices for tissue engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Vocal fold tissue repair in vivo using a synthetic extracellular matrix

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

In Vivo engineering of the vocal fold ECM with injectable HA hydrogels-late effects on tissue repair and biomechanics in a rabbit model

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Crosslinked hydrogels for tympanic membrane repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Influence of cross-linked hyaluronic acid hydrogels on neurite outgrowth and recovery from spinal cord injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Synthesis, characterization, and osteocompatibility evaluation of novel alanine-based polyphosphazenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Mechanical properties and osteocompatibility of novel biodegradable alanine based polyphosphazenes: Side group effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Chemically crosslinkable thermosensitive polyphosphazene gels as injectable materials for biomedical applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Injectable, dual cross-linkable polyphosphazene blend hydrogels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Design of polyphosphazene hydrogels with improved structural properties by use of star-shaped multithiol crosslinkers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Injectable hyaluronic acid-dextran hydrogels and effects of implantation in ferret vocal fold

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

New strategy for chemical modification of hyaluronic acid: preparation of functionalized derivatives and their use in the formation of novel biocompatible hydrogels

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Degradable, click poly(vinyl alcohol) hydrogels: characterization of degradation and cellular compatibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Enzyme optimization: moving from blind evolution to statistical exploration of sequence-function space

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

PEG hydrogels for the controlled release of biomolecules in regenerative medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Modular enzymatically crosslinked protein polymer hydrogels for in situ gelation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Enzymatically cross-linked hydrogels and their adhesive strength to biosurfaces

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Enzyme-mediated fast in situ formation of hydrogels from dextran-tyramine conjugates

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Enzymatically-crosslinked injectable hydrogels based on biomimetic dextran-hyaluronic acid conjugates for cartilage tissue engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Cell delivery using an injectable and adhesive transglutaminase-gelatin gel.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

An injectable, in situ enzymatically gellable, gelatin derivative for drug delivery and tissue engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Injectable biodegradable hydrogels with tunable mechanical properties for the stimulation of neurogenesic differentiation of human mesenchymal stem cells in 3D culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Synthesis and in vitro evaluation of enzymatically cross-linked elastin-like polypeptide gels for cartilaginous tissue repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Fibrin as a delivery system for therapeutic drugs and biomolecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

A comprehensive review of topical hemostatic agents: efficacy and recommendations for use.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Persistence of antibodies to the topical hemostat bovine thrombin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Optimizing the sterilization of PLGA scaffolds for use in tissue engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Impact of sterilization on the porous design and cell behavior in collagen sponges prepared for tissue engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Sterile, injectable cyclodextrin nanoparticles: effects of gamma irradiation and autoclaving

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

In situ cross-linkable novel alginate-dextran methacrylate IPN hydrogels for biomedical applications: mechanical characterization and drug delivery properties.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Bacterial inactivation by using near- and supercritical carbon dioxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Effective terminal sterilization using supercritical carbon dioxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

In vitro cytotoxicity of injectable and biodegradable poly(propylene fumarate)-based networks: unreacted macromers, cross-linked networks, and degradation products

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Photoresponsive PEG-Anthracene Grafted Hyaluronan as a Controlled-Delivery Biomaterial

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

An injectable thiol-acrylate poly(ethylene glycol) hydrogel for sustained release of methylprednisolone sodium succinate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Cathepsin K-sensitive poly(ethylene glycol) hydrogels for degradation in response to bone resorption

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Controlling the spatial distribution of ECM components in degradable PEG hydrogels for tissue engineering cartilage

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Antibiotic-loaded biomaterials and the risks for the spread of antibiotic resistance following their prophylactic and therapeutic clinical use

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Thiol-enes: Chemistry of the past with promise for the future

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Polymers as biomaterials for tissue engineering and controlled drug delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

Molecular Bioengineering of Biomaterials in the 1990s and Beyond: A Growing Liaison of Polymers with Molecular Biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJBM.A.34665

21 January 2018

Identifiers

DOI

10.1002/JBM.A.34665

1 reference

28 August 2017

1 reference