Echinocandins: production and applications (Q38086769)

28 August 2017

title

Echinocandins: production and applications (English)

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28 August 2017

Tamás Emri

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28 August 2017

László Majoros

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28 August 2017

Viktória Tóth

series ordinal

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28 August 2017

István Pócsi

series ordinal

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28 August 2017

language of work or name

English

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publication date

6 March 2013

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Applied Microbiology and Biotechnology

28 August 2017

published in

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28 August 2017

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28 August 2017

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28 August 2017

page(s)

3267-3284

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Establishing in vitro-in vivo correlations for Aspergillus fumigatus: the challenge of azoles versus echinocandins.

28 August 2017

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The echinocandins: three useful choices or three too many?

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Fitness and virulence costs of Candida albicans FKS1 hot spot mutations associated with echinocandin resistance.

21 January 2018

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A Multicenter, double-blind trial of a high-dose caspofungin treatment regimen versus a standard caspofungin treatment regimen for adult patients with invasive candidiasis.

21 January 2018

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Synthesis and antifungal activity of novel cationic pneumocandin B(o) derivatives

21 January 2018

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The antifungal echinocandin caspofungin acetate kills growing cells of Aspergillus fumigatus in vitro

21 January 2018

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Identification and characterization of the echinocandin B biosynthetic gene cluster from Emericella rugulosa NRRL 11440.

21 January 2018

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Efficacy of anidulafungin against Aspergillus niger in vitro and in vivo

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Combined therapy of voriconazole and anidulafungin in murine infections by Aspergillus flavus

21 January 2018

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Paradoxical effect of Echinocandins across Candida species in vitro: evidence for echinocandin-specific and candida species-related differences

21 January 2018

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Micafungin: a new echinocandin

21 January 2018

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Echinocandin antifungal drugs in fungal infections: a comparison

21 January 2018

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Characterizing the effects of caspofungin on Candida albicans, Candida parapsilosis, and Candida glabrata isolates by simultaneous time-kill and postantifungal-effect experiments

21 January 2018

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Assessment of the paradoxical effect of caspofungin in therapy of candidiasis

21 January 2018

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Susceptibility of Pneumocystis to echinocandins in suspension and biofilm cultures

21 January 2018

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Antibiotics that inhibit fungal cell wall development

21 January 2018

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Deciphering cell wall integrity signalling in Aspergillus fumigatus: identification and functional characterization of cell wall stress sensors and relevant Rho GTPases

21 January 2018

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A novel assay of biofilm antifungal activity reveals that amphotericin B and caspofungin lyseCandida albicanscells in biofilms

21 January 2018

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Transcriptional regulation of chitin synthases by calcineurin controls paradoxical growth of Aspergillus fumigatus in response to caspofungin

21 January 2018

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Discovery of micafungin (FK463): A novel antifungal drug derived from a natural product lead

21 January 2018

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FR131535, a novel water-soluble echinocandin-like lipopeptide: synthesis and biological properties

21 January 2018

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In-vitro activity of nikkomycin Z alone and in combination with polyenes, triazoles or echinocandins against Aspergillus fumigatus

21 January 2018

1 reference

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Cyclization of fungal nonribosomal peptides by a terminal condensation-like domain

21 January 2018

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A naturally occurring proline-to-alanine amino acid change in Fks1p in Candida parapsilosis, Candida orthopsilosis, and Candida metapsilosis accounts for reduced echinocandin susceptibility

21 January 2018

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Effect of Candida glabrata FKS1 and FKS2 mutations on echinocandin sensitivity and kinetics of 1,3-beta-D-glucan synthase: implication for the existing susceptibility breakpoint

21 January 2018

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Correlating echinocandin MIC and kinetic inhibition of fks1 mutant glucan synthases for Candida albicans: implications for interpretive breakpoints

21 January 2018

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Improved Detection of Candida sp. fks Hot Spot Mutants by Using the Method of the CLSI M27-A3 Document with the Addition of Bovine Serum Albumin

21 January 2018

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Characterization of Aspergillus fumigatus mutants with reduced susceptibility to caspofungin

21 January 2018

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The current status of species recognition and identification in Aspergillus

21 January 2018

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Caspofungin kills Candida albicans by causing both cellular apoptosis and necrosis

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Genetic modification of an echinocandin B-producing strain of Aspergillus nidulans to produce mutants blocked in sterigmatocystin biosynthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Sequence analysis and biochemical characterization of the nostopeptolide A biosynthetic gene cluster from Nostoc sp. GSV224.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Immobilized aculeacin A acylase from Actinoplanes utahensis: characterization of a novel biocatalyst

21 January 2018

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Acquired antifungal drug resistance in Aspergillus fumigatus: epidemiology and detection.

21 January 2018

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Echinocandin resistance due to simultaneous FKS mutation and increased cell wall chitin in a Candida albicans bloodstream isolate following brief exposure to caspofungin

21 January 2018

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Cloning and sequencing of the aculeacin A acylase-encoding gene from Actinoplanes utahensis and expression in Streptomyces lividans

21 January 2018

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Homologous subunits of 1,3-beta-glucan synthase are important for spore wall assembly in Saccharomyces cerevisiae

21 January 2018

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New Fks Hot Spot for Acquired Echinocandin Resistance in Saccharomyces cerevisiae and Its Contribution to Intrinsic Resistance of Scedosporium Species

21 January 2018

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Antimicrobial resistance: resistance to antifungal agents: mechanisms and clinical impact

21 January 2018

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21 January 2018

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Improvement of FR901379 production by mutant selection and medium optimization.

21 January 2018

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Candida albicans and Candida glabrata clinical isolates exhibiting reduced echinocandin susceptibility

21 January 2018

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Role for Fks1 in the intrinsic echinocandin resistance of Fusarium solani as evidenced by hybrid expression in Saccharomyces cerevisiae

21 January 2018

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Fks1 and Fks2 are functionally redundant but differentially regulated in Candida glabrata: implications for echinocandin resistance

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Total synthesis and antifungal evaluation of cyclic aminohexapeptides

21 January 2018

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A new sterigmatocystin-producing Emericella variant from agricultural desert soils

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Pharmacology and metabolism of anidulafungin, caspofungin and micafungin in the treatment of invasive candidosis - review of the literature

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Functional Dissection of Surfactin Synthetase Initiation Module Reveals Insights into the Mechanism of Lipoinitiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Increased antifungal activity of L-733,560, a water-soluble, semisynthetic pneumocandin, is due to enhanced inhibition of cell wall synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Morphological effects of lipopeptides against Aspergillus fumigatus correlate with activities against (1,3)-beta-D-glucan synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Semisynthetic modifications of hemiaminal function at ornithine unit of mulundocandin, towards chemical stability and antifungal activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

In vitro activity of calcineurin and heat shock protein 90 Inhibitors against Aspergillus fumigatus azole- and echinocandin-resistant strains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Elevated cell wall chitin in Candida albicans confers echinocandin resistance in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Cryptococcus neoformans resistance to echinocandins: (1,3)beta-glucan synthase activity is sensitive to echinocandins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Evaluation of the Etest method for susceptibility testing of Aspergillus spp. and Fusarium spp. to three echinocandins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Differential expression and function of two homologous subunits of yeast 1,3-beta-D-glucan synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Echinocandins: are they all the same?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Overexpression of Candida albicans CDR1, CDR2, or MDR1 does not produce significant changes in echinocandin susceptibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Metabolites of microorganisms. 143. Echinocandin B, a novel polypeptide-antibiotic from Aspergillus nidulans var. echinulatus: isolation and structural components

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Effects of serum on in vitro susceptibility testing of echinocandins

21 January 2018

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Caspofungin uptake is mediated by a high-affinity transporter in Candida albicans

21 January 2018

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Serum differentially alters the antifungal properties of echinocandin drugs

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Clinical practice guidelines for the management of candidiasis: 2009 update by the Infectious Diseases Society of America.

21 January 2018

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Specific substitutions in the echinocandin target Fks1p account for reduced susceptibility of rare laboratory and clinical Candida sp. isolates

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Resistance to echinocandin-class antifungal drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Current Perspectives on Echinocandin Class Drugs

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Effects of amino acid and trace element supplementation on pneumocandin production by Glarea lozoyensis: impact on titer, analogue levels, and the identification of new analogues of pneumocandin B(0).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Novel proline hydroxylase activities in the pneumocandin-producing fungus Glarea lozoyensis responsible for the formation of trans 3- and trans 4-hydroxyproline

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Antifungal drug resistance: mechanisms, epidemiology, and consequences for treatment

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Epidemiology of invasive candidiasis: a persistent public health problem

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Effects of cilofungin (LY121019) on carbohydrate and sterol composition of Candida albicans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Clinical breakpoints for the echinocandins and Candida revisited: integration of molecular, clinical, and microbiological data to arrive at species-specific interpretive criteria.

21 January 2018

1 reference

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Frequency of decreased susceptibility and resistance to echinocandins among fluconazole-resistant bloodstream isolates of Candida glabrata

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Functional analysis of Candida albicans GPI-anchored proteins: roles in cell wall integrity and caspofungin sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Scale up of a viscous fungal fermentation: application of scale-up criteria with regime analysis and operating boundary conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Distribution of sterigmatocystin in filamentous fungi.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

A Ser678Pro substitution in Fks1p confers resistance to echinocandin drugs in Aspergillus fumigatus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Disruption of the Aspergillus fumigatus ECM33 homologue results in rapid conidial germination, antifungal resistance and hypervirulence

21 January 2018

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Patients at high risk of invasive fungal infections: when and how to treat

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Micafungin: a review of its use in the prophylaxis and treatment of invasive Candida infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Five-Minute Exposure to Caspofungin Results in Prolonged Postantifungal Effects and Eliminates the Paradoxical Growth of Candida albicans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Paradoxical Effect of Caspofungin against Candida Bloodstream Isolates Is Mediated by Multiple Pathways but Eliminated in Human Serum

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Hsp90 governs echinocandin resistance in the pathogenic yeast Candida albicans via calcineurin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Global analysis of the evolution and mechanism of echinocandin resistance in Candida glabrata

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

In vitro study of Candida tropicalis isolates exhibiting paradoxical growth in the presence of high concentrations of caspofungin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Escape of Candida from caspofungin inhibition at concentrations above the MIC (paradoxical effect) accomplished by increased cell wall chitin; evidence for beta-1,6-glucan synthesis inhibition by caspofungin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Cryptocandin, a potent antimycotic from the endophytic fungus Cryptosporiopsis cf. quercina

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

A deacylation enzyme for aculeacin A, a neutral lipopeptide antibiotic, from Actinoplanes utahensis: purification and characterization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

W-1 solubilization and kinetics of inhibition by cilofungin of Candida albicans (1,3)-beta-D-glucan synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Newly discovered penicillin acylase activity of aculeacin A acylase from Actinoplanes utahensis

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Polyphasic characterization of "Aspergillus nidulans var. roseus" ATCC 58397.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

The echinocandin B producer fungus Aspergillus nidulans var. roseus ATCC 58397 does not possess innate resistance against its lipopeptide antimycotic

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Screening and characterization of microorganisms with FR901379 acylase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Cloning and expression of the FR901379 acylase gene from Streptomyces sp. no. 6907

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Madurella mycetomatis is not susceptible to the echinocandin class of antifungal agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Melanization of Cryptococcus neoformans and Histoplasma capsulatum reduces their susceptibilities to amphotericin B and caspofungin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

In vitro activity of a new pneumocandin antifungal agent, L-733,560 against azole-susceptible and -resistant Candida and Torulopsis species

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Reshuffling of Aspergillus fumigatus cell wall components chitin and β-glucan under the influence of caspofungin or nikkomycin Z alone or in combination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Stimulation of chitin synthesis rescues Candida albicans from echinocandins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Fungal echinocandin resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Elevated chitin content reduces the susceptibility of Candida species to caspofungin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Attenuation of echinocandin activity at elevated concentrations: a review of the paradoxical effect.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Role of DptE and DptF in the lipidation reaction of daptomycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Effect of aculeacin A, a wall-active antibiotic, on synthesis of the yeast cell wall

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Genome Sequence of the Fungus Glarea lozoyensis: the First Genome Sequence of a Species from the Helotiaceae Family

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Preparation and structure-activity relationships of simplified analogues of the antifungal agent cilofungin: a total synthesis approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

Effect of papulacandin B and aculeacin A on β-(1,3) glucan-synthase from geotrichum lactis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-013-4761-9

WF11899A, B and C, novel antifungal lipopeptides. I. Taxonomy, fermentation, isolation and physico-chemical properties.

21 January 2018

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12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.47.1084

Pneumocandins from Zalerion arboricola. IV. Biological evaluation of natural and semisynthetic pneumocandins for activity against Pneumocystis carinii and Candida species

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Pneumocandins from Zalerion arboricola. I. Discovery and isolation

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Studies on aculeacin. I. Isolation and characterization of aculeacin A

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Mulundocandin, a new lipopeptide antibiotic. II. Structure elucidation

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Mulundocandin, a new lipopeptide antibiotic. I. Taxonomy, fermentation, isolation and characterization

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Identifiers

DOI

10.1007/S00253-013-4761-9

1 reference

Dimensions Publication ID

28 August 2017

1033151326

0 references

1 reference