Role of Rac1-mineralocorticoid-receptor signalling in renal and cardiac disease (Q38072297)

28 August 2017

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title

Role of Rac1-mineralocorticoid-receptor signalling in renal and cardiac disease (English)

1 reference

28 August 2017

Miki Nagase

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28 August 2017

Toshiro Fujita

series ordinal

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28 August 2017

language of work or name

English

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publication date

8 January 2013

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Nature Reviews Nephrology

28 August 2017

published in

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28 August 2017

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28 August 2017

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28 August 2017

page(s)

86-98

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Mammalian Rho GTPases: new insights into their functions from in vivo studies

28 August 2017

cites work

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Efficacy of eplerenone versus enalapril as monotherapy in systemic hypertension

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RALES, EPHESUS and redox

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Modification of mineralocorticoid receptor function by Rac1 GTPase: implication in proteinuric kidney disease

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Angiotensin II- and salt-induced kidney injury through Rac1-mediated mineralocorticoid receptor activation

21 January 2018

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Rac1 GTPase in rodent kidneys is essential for salt-sensitive hypertension via a mineralocorticoid receptor-dependent pathway

21 January 2018

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Oxidative stress causes mineralocorticoid receptor activation in rat cardiomyocytes: role of small GTPase Rac1.

21 January 2018

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Cloning of a novel human Rac1b splice variant with increased expression in colorectal tumors

21 January 2018

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Rac1 is required for the formation of three germ layers during gastrulation.

21 January 2018

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GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors

21 January 2018

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GEFs and GAPs: critical elements in the control of small G proteins

21 January 2018

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Activation of Rac1 by shear stress in endothelial cells mediates both cytoskeletal reorganization and effects on gene expression.

21 January 2018

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Reactive oxygen species in mechanical stress-induced cardiac hypertrophy

21 January 2018

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Tumor necrosis factor alpha stimulation of Rac1 activity. Role of isoprenylcysteine carboxylmethyltransferase.

21 January 2018

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Coactivation of Rac1 and Cdc42 at lamellipodia and membrane ruffles induced by epidermal growth factor.

21 January 2018

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Activation of Rac and Cdc42 by integrins mediates cell spreading

21 January 2018

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Superoxide destabilization of beta-catenin augments apoptosis of high-glucose-stressed mesangial cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Rac1 is required for cardiomyocyte apoptosis during hyperglycemia

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Homocysteine activates NADH/NADPH oxidase through ceramide-stimulated Rac GTPase activity in rat mesangial cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Rac-MEKK3-MKK3 scaffolding for p38 MAPK activation during hyperosmotic shock.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Cell shrinkage as a signal to apoptosis in NIH 3T3 fibroblasts

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Rac1 mediates NaCl-induced superoxide generation in the thick ascending limb

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

GTPase-Rac enhances depolarization-induced superoxide production by the macula densa during tubuloglomerular feedback

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Angiotensin II-induced stimulation of p21-activated kinase and c-Jun NH2-terminal kinase is mediated by Rac1 and Nck.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Statins as antioxidant therapy for preventing cardiac myocyte hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

G alpha 12/13- and reactive oxygen species-dependent activation of c-Jun NH2-terminal kinase and p38 mitogen-activated protein kinase by angiotensin receptor stimulation in rat neonatal cardiomyocytes.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Podocyte as the target for aldosterone: roles of oxidative stress and Sgk1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Aldosterone induces superoxide generation via Rac1 activation in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Rho exchange factors in the cardiovascular system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Regulation of phagocyte oxygen radical production by the GTP-binding protein Rac 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Protection from reoxygenation injury by inhibition of rac1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

NOX enzymes and the biology of reactive oxygen

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

GTP-binding proteins of the Rho/Rac family: regulation, effectors and functions in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Focal segmental glomerulosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Cell biology and pathology of podocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Mechanisms of angiotensin II signaling on cytoskeleton of podocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Angiotensin II type 1 receptor overexpression in podocytes induces glomerulosclerosis in transgenic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Antagonistic Regulation of Actin Dynamics and Cell Motility by TRPC5 and TRPC6 Channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

uPAR: a versatile signalling orchestrator

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Modification of kidney barrier function by the urokinase receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Arhgap24 inactivates Rac1 in mouse podocytes, and a mutant form is associated with familial focal segmental glomerulosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

FilGAP, a Rho- and ROCK-regulated GAP for Rac binds filamin A to control actin remodelling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

HIV-1 Nef disrupts the podocyte actin cytoskeleton by interacting with diaphanous interacting protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Oxygen free radical release in human failing myocardium is associated with increased activity of rac1-GTPase and represents a target for statin treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

cAMP-binding protein Epac induces cardiomyocyte hypertrophy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Isoprenoids as mediators of the biological effects of statins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Initiation and transduction of stretch-induced RhoA and Rac1 activation through caveolae: cytoskeletal regulation of ERK translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

A requirement for the rac1 GTPase in the signal transduction pathway leading to cardiac myocyte hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Regulation of mitogen-activated protein kinases in cardiac myocytes through the small G protein Rac1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Statins inhibit beta-adrenergic receptor-stimulated apoptosis in adult rat ventricular myocytes via a Rac1-dependent mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Requirement of Rac1 in the development of cardiac hypertrophy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Angiotensin II activates signal transducer and activators of transcription 3 via Rac1 in atrial myocytes and fibroblasts: implication for the therapeutic effect of statin in atrial structural remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Altered focal adhesion regulation correlates with cardiomyopathy in mice expressing constitutively active rac1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Deficiency of rac1 blocks NADPH oxidase activation, inhibits endoplasmic reticulum stress, and reduces myocardial remodeling in a mouse model of type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Anti-inflammatory effects of atorvastatin improve left ventricular function in experimental diabetic cardiomyopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Rac1-induced connective tissue growth factor regulates connexin 43 and N-cadherin expression in atrial fibrillation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Rac1 is a critical mediator of endothelium-derived neurotrophic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Rac1 in cortical projection neurons is selectively required for midline crossing of commissural axonal formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Selective Rac-1 inhibition protects from diabetes-induced vascular injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Inhibition of Rac1 decreases the severity of pancreatitis and pancreatitis-associated lung injury in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

RAC1 inhibition targets amyloid precursor protein processing by gamma-secretase and decreases Abeta production in vitro and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Characterization of EHop-016, novel small molecule inhibitor of Rac GTPase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Activation of RhoA in podocytes induces focal segmental glomerulosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Mechanisms of the proteinuria induced by Rho GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Podocyte-specific loss of Cdc42 leads to congenital nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Coordination of Rho GTPase activities during cell protrusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Podocyte GTPases regulate kidney filter dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Cdc42 is an antihypertrophic molecular switch in the mouse heart

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Pak1 as a novel therapeutic target for antihypertrophic treatment in the heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Intracellular localization and functional effects of P21-activated kinase-1 (Pak1) in cardiac myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Cardiac-specific overexpression of RhoA results in sinus and atrioventricular nodal dysfunction and contractile failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

RhoA protects the mouse heart against ischemia/reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Aldosterone deficiency and mineralocorticoid receptor antagonism prevent angiotensin II-induced cardiac, renal, and vascular injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Direct regulation of blood pressure by smooth muscle cell mineralocorticoid receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Myeloid mineralocorticoid receptor controls macrophage polarization and cardiovascular hypertrophy and remodeling in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Angiotensin II and aldosterone regulate gene transcription via functional mineralocortocoid receptors in human coronary artery smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Spironolactone prevents diabetic nephropathy through an anti-inflammatory mechanism in type 2 diabetic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Mineralocorticoid receptor blockade enhances the antiproteinuric effect of an angiotensin II blocker through inhibiting podocyte injury in type 2 diabetic rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Spironolactone inhibits hyperglycemia-induced podocyte injury by attenuating ROS production.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Mineralocorticoid Blockade Reduces Vascular Injury in Stroke-Prone Hypertensive Rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Spironolactone in combination with cilazapril ameliorates proteinuria and renal interstitial fibrosis in rats with anti-Thy-1 irreversible nephritis

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

The role of aldosterone blockade in murine lupus nephritis

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Effects of mineralocorticoid and angiotensin II receptor blockers on proteinuria and glomerular podocyte protein expression in a model of minimal change nephrotic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Eplerenone potentiates the antiproteinuric effects of enalapril in experimental nephrotic syndrome.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Role of aldosterone in the remnant kidney model in the rat.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Aldosterone antagonists for preventing the progression of chronic kidney disease: a systematic review and meta-analysis.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Mitochondrial dysfunction mediates aldosterone-induced podocyte damage: a therapeutic target of PPARγ.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Activation of peroxisome proliferator-activated receptor-γ coactivator 1α ameliorates mitochondrial dysfunction and protects podocytes from aldosterone-induced injury

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Natriuretic peptide receptor guanylyl cyclase-A protects podocytes from aldosterone-induced glomerular injury

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Aldosterone induces apoptosis in rat podocytes: role of PI3-K/Akt and p38MAPK signaling pathways.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Glucocorticoids protect and enhance recovery of cultured murine podocytes via actin filament stabilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Dexamethasone prevents podocyte apoptosis induced by puromycin aminonucleoside: role of p53 and Bcl-2-related family proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Direct effects of dexamethasone on human podocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Reactive oxygen species have a causal role in multiple forms of insulin resistance

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Evolution of hormone-receptor complexity by molecular exploitation

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Molecular determinants for the tissue specificity of SERMs

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Selective estrogen-receptor modulators -- mechanisms of action and application to clinical practice.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Principles for modulation of the nuclear receptor superfamily

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Transgenic model of aldosterone-driven cardiac hypertrophy and heart failure

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Cardiac specific increase in aldosterone production induces coronary dysfunction in aldosterone synthase-transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Conditional mineralocorticoid receptor expression in the heart leads to life-threatening arrhythmias

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Ablation of mineralocorticoid receptors in myocytes but not in fibroblasts preserves cardiac function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Complementary and incremental mortality risk prediction by cortisol and aldosterone in chronic heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Eplerenone in Patients with Systolic Heart Failure and Mild Symptoms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Rationale and design of the 'aldosterone receptor blockade in diastolic heart failure' trial: a double-blind, randomized, placebo-controlled, parallel group study to determine the effects of spironolactone on exercise capacity and diastolic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Rationale and design of the treatment of preserved cardiac function heart failure with an aldosterone antagonist trial: a randomized, controlled study of spironolactone in patients with symptomatic heart failure and preserved ejection fraction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Oxidation of CaMKII determines the cardiotoxic effects of aldosterone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Deletion of mineralocorticoid receptors from macrophages protects against deoxycorticosterone/salt-induced cardiac fibrosis and increased blood pressure

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

P21-activated kinase-1 phosphorylates and transactivates estrogen receptor-alpha and promotes hyperplasia in mammary epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Ligand-independent activation of androgen receptors by Rho GTPase signaling in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Rho family Guanine nucleotide exchange factor Brx couples extracellular signals to the glucocorticoid signaling system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Weight loss and the renin-angiotensin-aldosterone system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Salt excess causes left ventricular diastolic dysfunction in rats with metabolic disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Role of osteopontin in cardiac fibrosis and remodeling in angiotensin II-induced cardiac hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Mineralocorticoid receptor affects AP-1 and nuclear factor-kappab activation in angiotensin II-induced cardiac injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Specific, nongenomic actions of steroid hormones

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Stimulation of NFkappa B activity by multiple signaling pathways requires PAK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Regulation of STAT3 by direct binding to the Rac1 GTPase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Rac1 and a GTPase-activating protein, MgcRacGAP, are required for nuclear translocation of STAT transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Rac1 activation controls nuclear localization of beta-catenin during canonical Wnt signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

The hsp90-FKBP52 complex links the mineralocorticoid receptor to motor proteins and persists bound to the receptor in early nuclear events.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

FKBP51 and FKBP52 in signaling and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Podocyte injury induces nuclear translocation of WTIP via microtubule-dependent transport.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Dose- and time-dependent glucocorticoid receptor signaling in podocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Myocardial subproteomic analysis of a constitutively active Rac1-expressing transgenic mouse with lethal myocardial hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Combinatorial control of gene expression by nuclear receptors and coregulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Regulation of progesterone receptor-mediated transcription by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Modulation of human mineralocorticoid receptor function by protein kinase A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Coactivation of the N-terminal transactivation of mineralocorticoid receptor by Ubc9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

NF-YC functions as a corepressor of agonist-bound mineralocorticoid receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Interactions of the mineralocorticoid receptor--within and without.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Actin in transcription and transcription regulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Activation of the NADPH oxidase involves the small GTP-binding protein p21rac1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Small GTP-binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Podocyte injury underlies the glomerulopathy of Dahl salt-hypertensive rats and is reversed by aldosterone blocker

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Integrin-linked kinase expression is elevated in human cardiac hypertrophy and induces hypertrophy in transgenic mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Role of Rac1 GTPase activation in atrial fibrillation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Inhibition of the Rac1 GTPase protects against nonlethal ischemia/reperfusion-induced necrosis and apoptosis in vivo

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Podocyte damage is a critical step in the development of glomerulosclerosis in the uninephrectomised-desoxycorticosterone hypertensive rat

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Mineralocorticoid Receptor Antagonist Reduces Renal Injury in Rodent Models of Types 1 and 2 Diabetes Mellitus

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Enhanced aldosterone signaling in the early nephropathy of rats with metabolic syndrome: possible contribution of fat-derived factors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Deletion of Cardiomyocyte Mineralocorticoid Receptor Ameliorates Adverse Remodeling After Myocardial Infarction

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

High plasma aldosterone levels on admission are associated with death in patients presenting with acute ST-elevation myocardial infarction

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Progressive impairment of kidneys and reproductive organs in mice lacking Rho GDIalpha

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Rho GTPases as modulators of the estrogen receptor transcriptional response

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Salt-induced nephropathy in obese spontaneously hypertensive rats via paradoxical activation of the mineralocorticoid receptor: role of oxidative stress

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Kinases and protein phosphorylation as regulators of steroid hormone action

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

The mineralocorticoid receptor: insights into its molecular and (patho)physiological biology

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Rationale and design of the Eplerenone combination Versus conventional Agents to Lower blood pressure on Urinary Antialbuminuric Treatment Effect (EVALUATE) trial: a double-blinded randomized placebo-controlled trial to evaluate the antialbuminuric

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2012.282

Reactive oxygen species alter gene expression in podocytes: induction of granulocyte macrophage-colony-stimulating factor

31 March 2020

1 reference

12 December 2020

Early nongenomic events in aldosterone action in renal collecting duct cells: PKCalpha activation, mineralocorticoid receptor phosphorylation, and cross-talk with the genomic response.

1 reference

12 December 2020

Ang II-stimulated migration of vascular smooth muscle cells is dependent on LR11 in mice

1 reference

12 December 2020

Mineralocorticoid excess, dietary sodium, and myocardial fibrosis

1 reference

12 December 2020

The selective mineralocorticoid receptor antagonist eplerenone is protective in mild anti-GBM glomeru-lonephritis

1 reference

12 December 2020

AND-34/BCAR3, a GDP exchange factor whose overexpression confers antiestrogen resistance, activates Rac, PAK1, and the cyclin D1 promoter

1 reference

12 December 2020

Oxygen, oxidative stress, hypoxia, and heart failure

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRNEPH.2012.282

1 reference

28 August 2017

1 reference