Immune classification of colorectal cancer patients: impressive but how complete? (Q38071673)

28 August 2017

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title

Immune classification of colorectal cancer patients: impressive but how complete? (English)

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28 August 2017

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Constantin N Baxevanis

series ordinal

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28 August 2017

Michael Papamichail

series ordinal

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28 August 2017

Sonia A Perez

series ordinal

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28 August 2017

language of work or name

English

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publication date

6 January 2013

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Expert Opinion on Biological Therapy

28 August 2017

published in

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28 August 2017

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28 August 2017

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28 August 2017

page(s)

517-526

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Tumor microenvironment and lymphocyte infiltration

28 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Type, density, and location of immune cells within human colorectal tumors predict clinical outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Intratumoral T cells, recurrence, and survival in epithelial ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Tumor-associated lymphocytes as an independent predictor of response to neoadjuvant chemotherapy in breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Tumor-infiltrating lymphocytes predict response to neoadjuvant chemotherapy in patients with breast carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Role of immature myeloid cells in mechanisms of immune evasion in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Disarming suppressor cells to improve immunotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Th17 cells in cancer: help or hindrance?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

T(H)17 cells in tumour immunity and immunotherapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Regulatory T cells and immune tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Interleukin 10 in the tumor microenvironment: a target for anticancer immunotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

CTLA4 blockade and GM-CSF combination immunotherapy alters the intratumor balance of effector and regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Peptide vaccination breaks tolerance to HER-2/neu by generating vaccine-specific FasL(+) CD4(+) T cells: first evidence for intratumor apoptotic regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

LAP+CD4+ T cells are suppressors accumulated in the tumor sites and associated with the progression of colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

IL-10 directly activates and expands tumor-resident CD8(+) T cells without de novo infiltration from secondary lymphoid organs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Endogenous IL-17 contributes to reduced tumor growth and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Transforming growth factor beta subverts the immune system into directly promoting tumor growth through interleukin-17

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

The central role of CD4(+) T cells in the antitumor immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Inflammation and prognosis in colorectal cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Will Rogers revisited: prospective observational study of survival of 3592 patients with colorectal cancer according to number of nodes examined by pathologists

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Lymph node evaluation and survival after curative resection of colon cancer: systematic review

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Systematic review of microsatellite instability and colorectal cancer prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

CpG island methylator phenotype, microsatellite instability, BRAF mutation and clinical outcome in colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Lymphocytic reaction to colorectal cancer is associated with longer survival, independent of lymph node count, microsatellite instability, and CpG island methylator phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Comparison of the prognostic value of inflammation-based pathologic and biochemical criteria in patients undergoing potentially curative resection for colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Prognostic significance of tumor-infiltrating lymphocytes for patients with colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Microsatellite instability and high content of activated cytotoxic lymphocytes identify colon cancer patients with a favorable prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Prognostic role of CD8+ tumor-infiltrating lymphocytes in stage III colorectal cancer with and without microsatellite instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Tumor-infiltrating lymphocytes and perforation in colon cancer predict positive response to 5-fluorouracil chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Effector memory T cells, early metastasis, and survival in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Natural killer cells in human cancer: from biological functions to clinical applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Immune system and prognosis in colorectal cancer: a detailed immunohistochemical analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Cutting edge: Phenotypic characterization and differentiation of human CD8+ T cells producing IL-17.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Anomalous type 17 response to viral infection by CD8+ T cells lacking T-bet and eomesodermin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

IL-6-dependent spontaneous proliferation is required for the induction of colitogenic IL-17-producing CD8+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Interplay between the TH17 and TReg cell lineages: a (co-)evolutionary perspective.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Th17 cytokines and mucosal immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

IL-17-producing human peripheral regulatory T cells retain suppressive function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Identification of IL-17-producing FOXP3+ regulatory T cells in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Phenotype, distribution, generation, and functional and clinical relevance of Th17 cells in the human tumor environments

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Phenotypic analysis of prostate-infiltrating lymphocytes reveals TH17 and Treg skewing

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Tumor-specific Th17-polarized cells eradicate large established melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Induction of Th17 cells in the tumor microenvironment improves survival in a murine model of pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

IL-17 enhances the net angiogenic activity and in vivo growth of human non-small cell lung cancer in SCID mice through promoting CXCR-2-dependent angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

IL-17 can promote tumor growth through an IL-6-Stat3 signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Different subsets of tumor infiltrating lymphocytes correlate with NPC progression in different ways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Generation and Differentiation of IL-17–Producing CD4+ T Cells in Malignant Pleural Effusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Plasticity of CD4(+) FoxP3(+) T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Eos mediates Foxp3-dependent gene silencing in CD4+ regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Foxp3 interacts with nuclear factor of activated T cells and NF-kappa B to repress cytokine gene expression and effector functions of T helper cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

GATA3-driven Th2 responses inhibit TGF-beta1-induced FOXP3 expression and the formation of regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Immune stimulatory receptor CD40 is required for T-cell suppression and T regulatory cell activation mediated by myeloid-derived suppressor cells in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Generation and accumulation of immunosuppressive adenosine by human CD4+CD25highFOXP3+ regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

The expression of the regulatory T cell-specific forkhead box transcription factor FoxP3 is associated with poor prognosis in ovarian cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

The prognostic value of FoxP3+ tumor-infiltrating lymphocytes in cancer: a critical review of the literature

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Systematic analysis of immune infiltrates in high-grade serous ovarian cancer reveals CD20, FoxP3 and TIA-1 as positive prognostic factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Regulatory (FoxP3+) T-cell tumor infiltration is a favorable prognostic factor in advanced colon cancer patients undergoing chemo or chemoimmunotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Stromal regulatory T-cells are associated with a favourable prognosis in gastric cancer of the cardia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Prognostic role of FOXP3+ regulatory T cells infiltrating human carcinomas: the paradox of colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Immune responses to malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

FOXP3 and survival in urinary bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

A reversed CD4/CD8 ratio of tumor-infiltrating lymphocytes and a high percentage of CD4+FOXP3+ regulatory T cells are significantly associated with clinical outcome in squamous cell carcinoma of the cervix

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Adoptive cell therapy for lymphoma with CD4 T cells depleted of CD137-expressing regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Signals through 4-1BB inhibit T regulatory cells by blocking IL-9 production enhancing antitumor responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Combining immunotherapy and targeted therapies in cancer treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Immunological aspects of cancer chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Down-regulation of zeta-chain expression in T cells: a biomarker of prognosis in cancer?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

The immune contexture in human tumours: impact on clinical outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Tumor-infiltrating lymphocytes: apparently good for melanoma patients. But why?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Tumor-Infiltrating FOXP3+ T Regulatory Cells Show Strong Prognostic Significance in Colorectal Cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Clinical Impact of Different Classes of Infiltrating T Cytotoxic and Helper Cells (Th1, Th2, Treg, Th17) in Patients with Colorectal Cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Pretreatment frequency of circulating IL-17+CD4+T-cells, but not Tregs, correlates with clinical response to whole-cell vaccination in prostate cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Gr-1+CD115+ Immature Myeloid Suppressor Cells Mediate the Development of Tumor-Induced T Regulatory Cells and T-Cell Anergy in Tumor-Bearing Host

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

CD147 (Basigin/Emmprin) identifies FoxP3+CD45RO+CTLA4+-activated human regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

Quantification of Regulatory T Cells Enables the Identification of High-Risk Breast Cancer Patients and Those at Risk of Late Relapse

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.2013.751971

10.1517/14712598.2013.751971

21 January 2018

Identifiers

DOI

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28 August 2017

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