Role of branched chain amino acids in cerebral ammonia homeostasis related to hepatic encephalopathy. (Q38078273)

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23 February 2020

review article

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title

Role of branched chain amino acids in cerebral ammonia homeostasis related to hepatic encephalopathy (English)

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23 February 2020

author

Helle S. Waagepetersen

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23 February 2020

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23 February 2020

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23 February 2020

Hendrik Vilstrup

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23 February 2020

Susanne Keiding

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23 February 2020

Arne Schousboe

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23 February 2020

Peter Ott

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23 February 2020

publication date

31 January 2013

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23 February 2020

published in

Metabolic Brain Disease

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23 February 2020

volume

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23 February 2020

issue

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23 February 2020

page(s)

209-215

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Metabolic alterations induced by ischemia in primary cultures of astrocytes: merging 13C NMR spectroscopy and metabolic flux analysis

23 February 2020

cites work

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Among the branched-chain amino acids, only valine metabolism is up-regulated in astrocytes during glutamate exposure.

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Plasma amino acids in patients with hepatic encephalopathy. Effects of amino acid infusions

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Cerebral blood flow and metabolism in chronically hyperammonemic rats: effect of an acute ammonia challenge

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Effect of acute ammonia intoxication on cerebral metabolism in rats with portacaval shunts

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Interaction between glutamate dehydrogenase (GDH) and L-leucine catabolic enzymes: intersecting metabolic pathways

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Branched-chain amino acid metabolon: interaction of glutamate dehydrogenase with the mitochondrial branched-chain aminotransferase (BCATm)

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L-Ornithine phenylacetate (OP): a novel treatment for hyperammonemia and hepatic encephalopathy

21 January 2018

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Ammonia effects on pyruvate/lactate production in astrocytes--interaction with glutamate

21 January 2018

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Brain alpha-ketoglutarate dehydrogenase complex: kinetic properties, regional distribution, and effects of inhibitors

21 January 2018

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Detoxification of ammonia in mouse cortical GABAergic cell cultures increases neuronal oxidative metabolism and reveals an emerging role for release of glucose-derived alanine

21 January 2018

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Nitrogen shuttling between neurons and glial cells during glutamate synthesis

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Effects of adrenergic agents on intracellular Ca2+ homeostasis and metabolism of glucose in astrocytes with an emphasis on pyruvate carboxylation, oxidative decarboxylation and recycling: implications for glutamate neurotransmission and excitotoxici

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Interorgan ammonia metabolism in liver failure

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Cerebral metabolic disturbances in the brain during acute liver failure: from hyperammonemia to energy failure and proteolysis

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Defective regulation of autophagy upon leucine deprivation reveals a targetable liability of human melanoma cells in vitro and in vivo.

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Brain metabolism of branched-chain amino acids

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Selective increase of brain lactate synthesis in experimental acute liver failure: results of a [H-C] nuclear magnetic resonance study

21 January 2018

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The metabolic role of isoleucine in detoxification of ammonia in cultured mouse neurons and astrocytes

21 January 2018

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Influence of Pathological Concentrations of Ammonia on Metabolic Fate of14C-Labeled Glutamate in Astrocytes in Primary Cultures

21 January 2018

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12 December 2020

Branched-chain amino acids increase arterial blood ammonia in spite of enhanced intrinsic muscle ammonia metabolism in patients with cirrhosis and healthy subjects

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12 December 2020

Inhibition of glutamine synthesis induces glutamate dehydrogenase-dependent ammonia fixation into alanine in co-cultures of astrocytes and neurons

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12 December 2020

A possible role of alanine for ammonia transfer between astrocytes and glutamatergic neurons

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12 December 2020

[Amino acid metabolism in liver diseases]

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12 December 2020

A novel branched-chain amino acid metabolon. Protein-protein interactions in a supramolecular complex

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12 December 2020

Modulation of the kinetic properties of phosphofructokinase by ammonium ions.

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Ammonia toxicity and cerebral oxidative metabolism

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NMR spectroscopic study on the metabolic fate of [3-(13)C]alanine in astrocytes, neurons, and cocultures: implications for glia-neuron interactions in neurotransmitter metabolism

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12 December 2020

10.1007/S11011-013-9381-7

Identifiers

DOI

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Dimensions Publication ID

23 February 2020

1008860583

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