Targeting plasma cells with proteasome inhibitors: possible roles in treating myasthenia gravis? (Q38068534)

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20 February 2020

review article

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title

Targeting plasma cells with proteasome inhibitors: possible roles in treating myasthenia gravis? (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23252897%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

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Pilar Martinez Martinez

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20 February 2020

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20 February 2020

Alejandro M Gomez

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20 February 2020

Nick Willcox

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20 February 2020

Peter C Molenaar

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20 February 2020

Wim Buurman

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20 February 2020

Marc H De Baets

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20 February 2020

language of work or name

English

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publication date

1 December 2012

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Annals of the New York Academy of Sciences

20 February 2020

number of pages

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based on heuristic

inferred from page(s)

published in

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20 February 2020

volume

1274

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20 February 2020

page(s)

48-59

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Antibody to acetylcholine receptor in myasthenia gravis. Prevalence, clinical correlates, and diagnostic value

20 February 2020

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Auto-antibodies to the receptor tyrosine kinase MuSK in patients with myasthenia gravis without acetylcholine receptor antibodies

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Autoantibodies to low‐density lipoprotein receptor–related protein 4 in myasthenia gravis

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Myasthenia gravis thymus: complement vulnerability of epithelial and myoid cells, complement attack on them, and correlations with autoantibody status.

21 January 2018

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The myasthenia gravis thymus: a rare source of human autoantibody-secreting plasma cells for testing potential therapeutics

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Fewer thymic changes in MuSK antibody-positive than in MuSK antibody-negative MG.

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Muscle-specific kinase myasthenia gravis IgG4 autoantibodies cause severe neuromuscular junction dysfunction in mice

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Antibody effector mechanisms in myasthenia gravis-pathogenesis at the neuromuscular junction

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Long-lasting treatment effect of rituximab in MuSK myasthenia.

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Competence and competition: the challenge of becoming a long-lived plasma cell

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Maintenance of the plasma cell pool is independent of memory B cells

21 January 2018

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Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1

21 January 2018

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XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation

21 January 2018

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Short-lived plasmablasts and long-lived plasma cells contribute to chronic humoral autoimmunity in NZB/W mice

21 January 2018

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Induction of long-term B-cell depletion in refractory rheumatoid arthritis patients preferentially affects autoreactive more than protective humoral immunity

21 January 2018

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Efficacy and safety of rituximab in moderately-to-severely active systemic lupus erythematosus: the randomized, double-blind, phase II/III systemic lupus erythematosus evaluation of rituximab trial

21 January 2018

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Long-lived autoreactive plasma cells drive persistent autoimmune inflammation

21 January 2018

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Proteasome inhibition causes apoptosis of normal human plasma cells preventing alloantibody production

21 January 2018

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Resistance of long-lived lymphocytes and plasma cells in rat lymph nodes to treatment with prednisone, cyclophosphamide, 6-mercaptopurine, and actinomycin D.

21 January 2018

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United States Food and Drug Administration approval summary: bortezomib for the treatment of progressive multiple myeloma after one prior therapy

21 January 2018

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Subcutaneous versus intravenous administration of bortezomib in patients with relapsed multiple myeloma: a randomised, phase 3, non-inferiority study

21 January 2018

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Efficacy and safety of once-weekly bortezomib in multiple myeloma patients.

21 January 2018

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An open-label, single-arm, phase 2 study of single-agent carfilzomib in patients with relapsed and/or refractory multiple myeloma who have been previously treated with bortezomib

21 January 2018

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Nonproteasomal Targets of the Proteasome Inhibitors Bortezomib and Carfilzomib: a Link to Clinical Adverse Events

21 January 2018

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Proteasome inhibitors induce a terminal unfolded protein response in multiple myeloma cells

21 January 2018

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NF-kappa B as a therapeutic target in multiple myeloma

21 January 2018

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Extensive immunoglobulin production sensitizes myeloma cells for proteasome inhibition.

21 January 2018

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The proteasome inhibitor bortezomib depletes plasma cells and protects mice with lupus-like disease from nephritis

21 January 2018

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Proteasome inhibition with bortezomib depletes plasma cells and autoantibodies in experimental autoimmune myasthenia gravis.

21 January 2018

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Bortezomib and sirolimus inhibit the chronic active antibody-mediated rejection in experimental renal transplantation in the rat.

21 January 2018

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Bortezomib delays the onset of factor VIII inhibitors in experimental hemophilia A, but fails to eliminate established anti-factor VIII IgG-producing cells

21 January 2018

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Beneficial effect of novel proteasome inhibitors in murine lupus via dual inhibition of type I interferon and autoantibody-secreting cells

21 January 2018

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Myeloperoxidase-specific plasma cell depletion by bortezomib protects from anti-neutrophil cytoplasmic autoantibodies-induced glomerulonephritis

21 January 2018

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21 January 2018

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Bortezomib or high-dose dexamethasone for relapsed multiple myeloma

21 January 2018

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21 January 2018

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The Impact of Proteasome Inhibition on Alloantibody-Producing Plasma Cells In Vivo

21 January 2018

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Protective immunity remains intact after antibody removal by means of proteasome inhibition

21 January 2018

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Bortezomib as the sole post-renal transplantation desensitization agent does not decrease donor-specific anti-HLA antibodies

21 January 2018

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Comparison between bortezomib and rituximab in the treatment of antibody-mediated renal allograft rejection.

21 January 2018

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Successful use of bortezomib in a patient with systemic lupus erythematosus and multiple myeloma

21 January 2018

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21 January 2018

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Proteasome inhibitor-based primary therapy for antibody-mediated renal allograft rejection

21 January 2018

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Early and Late Acute Antibody-Mediated Rejection Differ Immunologically and in Response to Proteasome Inhibition

21 January 2018

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Therapeutic inhibition of proteasomes in systemic lupus erythematosus

21 January 2018

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Immunosuppressive therapies in myasthenia gravis

21 January 2018

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A randomized double-blind trial of prednisolone alone or with azathioprine in myasthenia gravis. Myasthenia Gravis Study Group

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1749-6632.2012.06824.X

Single-agent bortezomib in previously untreated multiple myeloma: efficacy, characterization of peripheral neuropathy, and molecular correlations with response and neuropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2012.06824.X

Peripheral neuropathy during bortezomib treatment of multiple myeloma: a review of recent studies

21 January 2018

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Discovery and development of second-generation proteasome inhibitors

21 January 2018

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The selective adhesion molecule inhibitor Natalizumab decreases multiple myeloma cell growth in the bone marrow microenvironment: therapeutic implications

21 January 2018

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Blockade of interleukin-6 signalling with siltuximab enhances melphalan cytotoxicity in preclinical models of multiple myeloma

21 January 2018

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Plerixafor as first- and second-line strategies for autologous stem cell mobilization in patients with non-Hodgkin's lymphoma or multiple myeloma

21 January 2018

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Elotuzumab in combination with lenalidomide and low-dose dexamethasone in relapsed or refractory multiple myeloma

21 January 2018

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Daratumumab, a novel therapeutic human CD38 monoclonal antibody, induces killing of multiple myeloma and other hematological tumors.

21 January 2018

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The monoclonal antibody nBT062 conjugated to cytotoxic Maytansinoids has selective cytotoxicity against CD138-positive multiple myeloma cells in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1749-6632.2012.06824.X

Plasma exchange and immunosuppressive drug treatment in myasthenia gravis: no evidence for synergy

21 January 2018

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10.1111/J.1749-6632.2012.06824.X

21 January 2018

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23252897%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

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