Anti-tumour immunotherapy with Vγ9Vδ2 T lymphocytes: from the bench to the bedside (Q38051730)

27 August 2017

title

Anti-tumour immunotherapy with Vγ9Vδ2 T lymphocytes: from the bench to the bedside (English)

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27 August 2017

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Mounia S Braza

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27 August 2017

Bernard Klein

series ordinal

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27 August 2017

language of work or name

English

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publication date

15 October 2012

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British Journal of Haematology

27 August 2017

published in

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27 August 2017

volume

160

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27 August 2017

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27 August 2017

page(s)

123-132

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Isopentenyl pyrophosphate-activated CD56+ {gamma}{delta} T lymphocytes display potent antitumor activity toward human squamous cell carcinoma

27 August 2017

cites work

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Gammadelta T cell immune manipulation during chronic phase of simian-human immunodeficiency virus infection [corrected] confers immunological benefits

21 January 2018

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Dendritic cells and the control of immunity

21 January 2018

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Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA

21 January 2018

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High phosphoantigen levels in bisphosphonate-treated human breast tumors promote Vgamma9Vdelta2 T-cell chemotaxis and cytotoxicity in vivo.

21 January 2018

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Regulatory T cells in cancer

21 January 2018

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The function of gammadelta T cells in innate immunity

21 January 2018

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Cross-presenting human gammadelta T cells induce robust CD8+ alphabeta T cell responses

21 January 2018

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T-cell killing of primary follicular lymphoma cells is dramatically potentiated by GA101, a type II glycoengineered anti-CD20 monoclonal antibody

21 January 2018

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In vitro expansion of gamma delta T cells with anti-myeloma cell activity by Phosphostim and IL-2 in patients with multiple myeloma

21 January 2018

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Aminobisphosphonate-pretreated dendritic cells trigger successful Vgamma9Vdelta2 T cell amplification for immunotherapy in advanced cancer patients

21 January 2018

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Differentiation, phenotype, and function of interleukin-17-producing human Vγ9Vδ2 T cells.

21 January 2018

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Do human T cells respond to M tuberculosis protein antigens?

21 January 2018

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A tuberculosis vaccine based on phosphoantigens and fusion proteins induces distinct γδ and αβ T cell responses in primates

21 January 2018

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Antigen recognition by gammadelta T cells

21 January 2018

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Reciprocal activating interaction between dendritic cells and pamidronate-stimulated gammadelta T cells: role of CD86 and inflammatory cytokines

21 January 2018

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V gamma 9V delta 2 T cell response to colon carcinoma cells

21 January 2018

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V gamma 9V delta 2 T lymphocytes efficiently recognize and kill zoledronate-sensitized, imatinib-sensitive, and imatinib-resistant chronic myelogenous leukemia cells.

21 January 2018

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Potentiation of antigen-stimulated V gamma 9V delta 2 T cell cytokine production by immature dendritic cells (DC) and reciprocal effect on DC maturation

21 January 2018

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Targeting human {gamma}delta} T cells with zoledronate and interleukin-2 for immunotherapy of hormone-refractory prostate cancer

21 January 2018

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IL-15 produced and trans-presented by DCs underlies homeostatic competition between CD8 and {gamma}{delta} T cells in vivo

21 January 2018

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gammadelta-T cells expressing NK receptors predominate over NK cells and conventional T cells in the innate IFN-gamma response to Plasmodium falciparum malaria

21 January 2018

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Promiscuity and the single receptor: NKG2D.

21 January 2018

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{gamma}{delta} T cell homeostasis is established in competition with {alpha}{beta} T cells and NK cells

21 January 2018

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Immunomodulating role of bisphosphonates on human gamma delta T cells: an intriguing and promising aspect of their antitumour activity

21 January 2018

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Intratumoral balance of regulatory and cytotoxic T cells is associated with prognosis of hepatocellular carcinoma after resection.

21 January 2018

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Bromohydrin pyrophosphate enhances antibody-dependent cell-mediated cytotoxicity induced by therapeutic antibodies

21 January 2018

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Immunosurveillance and immunoregulation by gammadelta T cells

21 January 2018

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Human T cell receptor gammadelta cells recognize endogenous mevalonate metabolites in tumor cells

21 January 2018

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Recognition of stress-induced MHC molecules by intestinal epithelial gammadelta T cells

21 January 2018

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Broad tumor-associated expression and recognition by tumor-derived gamma delta T cells of MICA and MICB

21 January 2018

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The participation of mesenchymal stem cells in tumor stroma formation and their application as targeted-gene delivery vehicles

21 January 2018

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Genetic requirements for the development and differentiation of interleukin-17-producing γδ T cells

21 January 2018

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Type I IFN signaling constrains IL-17A/F secretion by gammadelta T cells during bacterial infections

21 January 2018

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Human γδ T lymphocytes are licensed for professional antigen presentation by interaction with opsonized target cells

21 January 2018

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Control of regulatory T cell development by the transcription factor Foxp3

21 January 2018

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Immunotherapy targeting colon cancer stem cells

21 January 2018

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An integrated view of suppressor T cell subsets in immunoregulation

21 January 2018

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Adoptive immunotherapy of lung cancer with immobilized anti-TCRgammadelta antibody-expanded human gammadelta T-cells in peripheral blood

21 January 2018

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Mesenchymal stem cells within tumour stroma promote breast cancer metastasis

21 January 2018

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Safety profile and anti-tumor effects of adoptive immunotherapy using gamma-delta T cells against advanced renal cell carcinoma: a pilot study.

21 January 2018

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Zoledronate facilitates large-scale ex vivo expansion of functional gammadelta T cells from cancer patients for use in adoptive immunotherapy

21 January 2018

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Gammadelta T cells - innate immune lymphocytes?

21 January 2018

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Inhibition of phosphoantigen-mediated gammadelta T-cell proliferation by CD4+ CD25+ FoxP3+ regulatory T cells

21 January 2018

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Reduced expression of the mevalonate pathway enzyme farnesyl pyrophosphate synthase unveils recognition of tumor cells by Vgamma9Vdelta2 T cells

21 January 2018

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Coculture with dendritic cells promotes proliferation but not cytotoxic activity of gamma/delta T cells

21 January 2018

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Ex vivo expanded human Vgamma9Vdelta2+ gammadelta-T cells mediate innate antitumor activity against human prostate cancer cells in vitro.

21 January 2018

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Protective immunosurveillance and therapeutic antitumor activity of gammadelta T cells demonstrated in a mouse model of prostate cancer

21 January 2018

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IL-17 production is dominated by gammadelta T cells rather than CD4 T cells during Mycobacterium tuberculosis infection

21 January 2018

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Contribution of IL-17-producing gamma delta T cells to the efficacy of anticancer chemotherapy

21 January 2018

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Human gammadelta T lymphocytes induce robust NK cell-mediated antitumor cytotoxicity through CD137 engagement

21 January 2018

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Redirecting αβ T cells against cancer cells by transfer of a broadly tumor-reactive γδT-cell receptor

21 January 2018

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A regulatory cross-talk between Vgamma9Vdelta2 T lymphocytes and mesenchymal stem cells

21 January 2018

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PGE2 inhibits natural killer and gamma delta T cell cytotoxicity triggered by NKR and TCR through a cAMP-mediated PKA type I-dependent signaling

21 January 2018

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Prolonged antigen survival and cytosolic export in cross-presenting human gammadelta T cells

21 January 2018

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gammadelta T cells: novel initiators of adaptive immunity.

21 January 2018

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Reciprocal interactions between human mesenchymal stem cells and gammadelta T cells or invariant natural killer T cells

21 January 2018

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Type 1 responses of human Vγ9Vδ2 T cells to influenza A viruses

21 January 2018

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CD27 is a thymic determinant of the balance between interferon-gamma- and interleukin 17-producing gammadelta T cell subsets

21 January 2018

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Cutting edge: adaptive versus innate receptor signals selectively control the pool sizes of murine IFN-γ- or IL-17-producing γδ T cells upon infection

21 January 2018

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Peripheral blood monocytes are responsible for gammadelta T cell activation induced by zoledronic acid through accumulation of IPP/DMAPP.

21 January 2018

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Interferon-gamma does not break, but promotes the immunosuppressive capacity of adult human mesenchymal stem cells

21 January 2018

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Anti-tumor cytotoxicity of gammadelta T cells expanded from peripheral blood cells of patients with myeloma and lymphoma

21 January 2018

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Reduced immune response to Borrelia burgdorferi in the absence of γδ T cells.

21 January 2018

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In vivo immunomanipulation of V gamma 9V delta 2 T cells with a synthetic phosphoantigen in a preclinical nonhuman primate model

21 January 2018

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Design, synthesis, and biological evaluation of novel aminobisphosphonates possessing an in vivo antitumor activity through a gammadelta-T lymphocytes-mediated activation mechanism.

21 January 2018

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Only a subset of phosphoantigen-responsive gamma9delta2 T cells mediate protective tuberculosis immunity

21 January 2018

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Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity.

21 January 2018

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IL‐17 production by γδ T cells is important for the antitumor effect of Mycobacterium bovis bacillus Calmette‐Guérin treatment against bladder cancer

21 January 2018

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Self/non-self discrimination by human gammadelta T cells: simple solutions for a complex issue?

21 January 2018

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IL-21-mediated potentiation of antitumor cytolytic and proinflammatory responses of human V gamma 9V delta 2 T cells for adoptive immunotherapy.

21 January 2018

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Alkylamines cause Vgamma9Vdelta2 T-cell activation and proliferation by inhibiting the mevalonate pathway

21 January 2018

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V gamma 9 V delta 2 T cell cytotoxicity against tumor cells is enhanced by monoclonal antibody drugs--rituximab and trastuzumab

21 January 2018

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Phosphostim-activated gamma delta T cells kill autologous metastatic renal cell carcinoma.

21 January 2018

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Chemokine receptors expression and migration potential of tumor-infiltrating and peripheral-expanded Vgamma9Vdelta2 T cells from renal cell carcinoma patients.

21 January 2018

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Innate or adaptive immunity? The example of natural killer cells

21 January 2018

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Gammadelta T cells for immune therapy of patients with lymphoid malignancies

21 January 2018

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Peripheral gamma delta T-cell deficit in nasopharyngeal carcinoma

21 January 2018

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Phase-I study of Innacell γδ™, an autologous cell-therapy product highly enriched in γ9δ2 T lymphocytes, in combination with IL-2, in patients with metastatic renal cell carcinoma

21 January 2018

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21 January 2018

Identifiers

DOI

10.1111/BJH.12090

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27 August 2017

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