Regulation of human DNA polymerase delta in the cellular responses to DNA damage (Q38050704)

27 August 2017

title

Regulation of human DNA polymerase delta in the cellular responses to DNA damage (English)

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27 August 2017

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Zhongtao Zhang

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Marietta Y W T Lee

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27 August 2017

Sufang Zhang

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27 August 2017

Szu Hua Sharon Lin

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27 August 2017

Jennifer Chea

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27 August 2017

Xiaoxiao Wang

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27 August 2017

Christine LeRoy

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27 August 2017

Agnes Wong

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27 August 2017

Ernest Y C Lee

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27 August 2017

publication date

10 October 2012

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Environmental and Molecular Mutagenesis

27 August 2017

published in

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27 August 2017

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27 August 2017

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27 August 2017

page(s)

683-698

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PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4Cdt2 ubiquitin ligase complex

27 August 2017

cites work

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Roles of PCNA-binding and ubiquitin-binding domains in human DNA polymerase eta in translesion DNA synthesis

21 January 2018

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PCNA binding domains in all three subunits of yeast DNA polymerase δ modulate its function in DNA replication

21 January 2018

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Eukaryotic DNA damage tolerance and translesion synthesis through covalent modifications of PCNA.

21 January 2018

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Sequential assembly of translesion DNA polymerases at UV-induced DNA damage sites

21 January 2018

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DNA polymerase δ and ζ switch by sharing accessory subunits of DNA polymerase δ

21 January 2018

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The structure and mechanism of protein phosphatases: insights into catalysis and regulation

21 January 2018

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UV irradiation triggers ubiquitin-dependent degradation of p21(WAF1) to promote DNA repair

21 January 2018

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Studies on Human DNA Polymerase ϵ and GINS Complex and Their Role in DNA Replication

21 January 2018

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Structure of the ubiquitin-binding zinc finger domain of human DNA Y-polymerase eta

21 January 2018

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Ubiquitination and deubiquitination of PCNA in response to stalling of the replication fork

21 January 2018

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Structural and thermodynamic analysis of human PCNA with peptides derived from DNA polymerase-delta p66 subunit and flap endonuclease-1.

21 January 2018

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Polymerase dynamics at the eukaryotic DNA replication fork

21 January 2018

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Structural Analysis of the Conserved Ubiquitin-binding Motifs (UBMs) of the Translesion Polymerase iota in Complex with Ubiquitin

21 January 2018

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A new mammalian DNA polymerase with 3' to 5' exonuclease activity: DNA polymerase delta

21 January 2018

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Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint.

21 January 2018

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Functional diversity of protein phosphatase-1, a cellular economizer and reset button

21 January 2018

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Crystal structure of the GINS complex and functional insights into its role in DNA replication

21 January 2018

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Checkpoint regulation of replication dynamics in UV-irradiated human cells.

21 January 2018

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Spatiotemporal recruitment of human DNA polymerase delta to sites of UV damage

21 January 2018

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Ubiquitination of PCNA and its essential role in eukaryotic translesion synthesis

21 January 2018

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ATR: an essential regulator of genome integrity

21 January 2018

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The mammalian DNA replication elongation checkpoint: implication of Chk1 and relationship with origin firing as determined by single DNA molecule and single cell analyses

21 January 2018

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The structural basis for MCM2-7 helicase activation by GINS and Cdc45.

21 January 2018

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Structure of an archaeal PCNA1-PCNA2-FEN1 complex: elucidating PCNA subunit and client enzyme specificity

21 January 2018

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Fidelity of DNA synthesis catalyzed by human DNA polymerase alpha and HIV-1 reverse transcriptase: effect of reaction pH

21 January 2018

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WAF1, a potential mediator of p53 tumor suppression

21 January 2018

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Cdk-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalyzed by the DNA polymerase delta holoenzyme

21 January 2018

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ATR: a master conductor of cellular responses to DNA replication stress

21 January 2018

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Protein phosphatase-1 is targeted to DNA polymerase delta via an interaction with the p68 subunit.

21 January 2018

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DNA polymerases that propagate the eukaryotic DNA replication fork

21 January 2018

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Idling by DNA polymerase delta maintains a ligatable nick during lagging-strand DNA replication

21 January 2018

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Characterization of the two small subunits of Saccharomyces cerevisiae DNA polymerase delta

21 January 2018

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Regulation of DNA damage response pathways by the cullin-RING ubiquitin ligases

21 January 2018

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Structural and functional relationships of human DNA polymerases

21 January 2018

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The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

21 January 2018

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The DNA damage response: ten years after

21 January 2018

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Mechanism of CRL4(Cdt2), a PCNA-dependent E3 ubiquitin ligase

21 January 2018

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Beyond translesion synthesis: polymerase κ fidelity as a potential determinant of microsatellite stability

21 January 2018

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RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO.

21 January 2018

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Bumps in the road: how replicative DNA polymerases see DNA damage

21 January 2018

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Roles of POLD4, smallest subunit of DNA polymerase delta, in nuclear structures and genomic stability of human cells

21 January 2018

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Regulation of DNA polymerase POLD4 influences genomic instability in lung cancer.

21 January 2018

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RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly

21 January 2018

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Isolation and identification of the third subunit of mammalian DNA polymerase delta by PCNA-affinity chromatography of mouse FM3A cell extracts

21 January 2018

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Conformational coupling in DNA polymerase fidelity

21 January 2018

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Pol31 and Pol32 subunits of yeast DNA polymerase δ are also essential subunits of DNA polymerase ζ.

21 January 2018

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Properties of the human Cdc45/Mcm2-7/GINS helicase complex and its action with DNA polymerase epsilon in rolling circle DNA synthesis.

21 January 2018

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Localization of Y-family polymerases and the DNA polymerase switch in mammalian cells.

21 January 2018

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Interaction of human DNA polymerase eta with monoubiquitinated PCNA: a possible mechanism for the polymerase switch in response to DNA damage

21 January 2018

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The human intra-S checkpoint response to UVC-induced DNA damage

21 January 2018

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The proofreading 3'-->5' exonuclease activity of DNA polymerases: a kinetic barrier to translesion DNA synthesis

21 January 2018

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The CRL4Cdt2 ubiquitin ligase targets the degradation of p21Cip1 to control replication licensing

21 January 2018

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21 January 2018

DNA replication fidelity

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Dividing the workload at a eukaryotic replication fork

21 January 2018

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Sliding clamps of DNA polymerases

21 January 2018

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Purification of deoxyribonucleic acid polymerase delta from calf thymus: partial characterization of physical properties

21 January 2018

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Further studies on calf thymus DNA polymerase delta purified to homogeneity by a new procedure

21 January 2018

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Ubiquitin‐family modifications in the replication of DNA damage

21 January 2018

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Phosphorylation of the C subunit (p66) of human DNA polymerase delta.

21 January 2018

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Direct interaction of p21 with p50, the small subunit of human DNA polymerase delta

21 January 2018

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Functional roles of p12, the fourth subunit of human DNA polymerase delta

21 January 2018

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Localization of checkpoint and repair proteins in eukaryotes

21 January 2018

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Identification of a fourth subunit of mammalian DNA polymerase delta

21 January 2018

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Identification of a novel protein, PDIP38, that interacts with the p50 subunit of DNA polymerase delta and proliferating cell nuclear antigen

21 January 2018

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Flap endonuclease 1: a central component of DNA metabolism

21 January 2018

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Identification of DNA replication and cell cycle proteins that interact with PCNA

21 January 2018

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Direct interaction of proliferating cell nuclear antigen with the small subunit of DNA polymerase delta

21 January 2018

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Structure and function of the GINS complex, a key component of the eukaryotic replisome

21 January 2018

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DNA replication-coupled PCNA mono-ubiquitination and polymerase switching in a human in vitro system.

21 January 2018

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Perturbed gap-filling synthesis in nucleotide excision repair causes histone H2AX phosphorylation in human quiescent cells

21 January 2018

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Enzymatic switching for efficient and accurate translesion DNA replication.

21 January 2018

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Evidence for extrinsic exonucleolytic proofreading.

21 January 2018

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Division of labor at the eukaryotic replication fork

21 January 2018

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Preferential DNA repair of an active gene in human cells

21 January 2018

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DNA damage alters DNA polymerase delta to a form that exhibits increased discrimination against modified template bases and mismatched primers

21 January 2018

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The p12 subunit of human polymerase delta modulates the rate and fidelity of DNA synthesis

21 January 2018

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The major roles of DNA polymerases epsilon and delta at the eukaryotic replication fork are evolutionarily conserved

21 January 2018

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Evidence that DNA polymerase delta isolated by immunoaffinity chromatography exhibits high-molecular weight characteristics and is associated with the KIAA0039 protein and RPA.

21 January 2018

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Sequential recruitment of the repair factors during NER: the role of XPG in initiating the resynthesis step.

21 January 2018

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DNA polymerase POLN participates in cross-link repair and homologous recombination

21 January 2018

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A splicing mutation affecting expression of ataxia-telangiectasia and Rad3-related protein (ATR) results in Seckel syndrome

21 January 2018

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Three DNA polymerases, recruited by different mechanisms, carry out NER repair synthesis in human cells

21 January 2018

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Separate roles of structured and unstructured regions of Y-family DNA polymerases

21 January 2018

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Global, in vivo, and site-specific phosphorylation dynamics in signaling networks

21 January 2018

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A flexible interface between DNA ligase and PCNA supports conformational switching and efficient ligation of DNA.

21 January 2018

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DNA polymerases at the eukaryotic fork-20 years later

21 January 2018

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Reconstitution of human DNA polymerase delta using recombinant baculoviruses: the p12 subunit potentiates DNA polymerizing activity of the four-subunit enzyme

21 January 2018

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DNA topoisomerases and their poisoning by anticancer and antibacterial drugs

21 January 2018

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DNA polymerase epsilon - more than a polymerase.

21 January 2018

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Functional identity of proliferating cell nuclear antigen and a DNA polymerase-delta auxiliary protein

21 January 2018

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DNA polymerase epsilon: a polymerase of unusual size (and complexity).

21 January 2018

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Yeast DNA polymerase epsilon participates in leading-strand DNA replication

21 January 2018

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Phosphorylation of the p68 subunit of Pol δ acts as a molecular switch to regulate its interaction with PCNA.

21 January 2018

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Cdm1, the smallest subunit of DNA polymerase d in the fission yeast Schizosaccharomyces pombe, is non-essential for growth and division

21 January 2018

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Distinctive activities of DNA polymerases during human DNA replication

21 January 2018

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Y-family DNA polymerases and their role in tolerance of cellular DNA damage.

21 January 2018

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Spontaneous homologous recombination is induced by collapsed replication forks that are caused by endogenous DNA single-strand breaks

21 January 2018

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The ATM-Chk2 and ATR-Chk1 pathways in DNA damage signaling and cancer

21 January 2018

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PCNA-coupled p21 degradation after DNA damage: The exception that confirms the rule?

21 January 2018

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P21Cip1/WAF1 downregulation is required for efficient PCNA ubiquitination after UV irradiation

21 January 2018

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p21 differentially regulates DNA replication and DNA-repair-associated processes after UV irradiation.

21 January 2018

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Structural basis of high-fidelity DNA synthesis by yeast DNA polymerase delta

21 January 2018

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DNA polymerases alpha, delta, and epsilon: three distinct enzymes from HeLa cells

21 January 2018

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The human Tim/Tipin complex coordinates an Intra-S checkpoint response to UV that slows replication fork displacement

21 January 2018

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Sequential assembly of the nucleotide excision repair factors in vivo

21 January 2018

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UV-induced photolesions elicit ATR-kinase-dependent signaling in non-cycling cells through nucleotide excision repair-dependent and -independent pathways

21 January 2018

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The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA

21 January 2018

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P50, the small subunit of DNA polymerase delta, is required for mediation of the interaction of polymerase delta subassemblies with PCNA.

21 January 2018

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The structural basis for the mutagenicity of O6-methyl-guanine lesions

21 January 2018

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Characterization of the p125 subunit of human DNA polymerase delta and its deletion mutants. Interaction with cyclin-dependent kinase-cyclins

21 January 2018

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Reconstitution and characterization of the human DNA polymerase delta four-subunit holoenzyme

21 January 2018

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p21 is a universal inhibitor of cyclin kinases

21 January 2018

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RAP80 and RNF8, key players in the recruitment of repair proteins to DNA damage sites

21 January 2018

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Molecular cloning of the cDNA for the catalytic subunit of human DNA polymerase delta

21 January 2018

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What a difference a decade makes: insights into translesion DNA synthesis

21 January 2018

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Highly error-free role of DNA polymerase eta in the replicative bypass of UV-induced pyrimidine dimers in mouse and human cells

21 January 2018

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Error-free replicative bypass of (6-4) photoproducts by DNA polymerase zeta in mouse and human cells

21 January 2018

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Primary structure of the catalytic subunit of calf thymus DNA polymerase .delta.: sequence similarities with other DNA polymerases

21 January 2018

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Direct interaction of proliferating cell nuclear antigen with the p125 catalytic subunit of mammalian DNA polymerase delta

21 January 2018

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A novel DNA damage response: rapid degradation of the p12 subunit of dna polymerase delta

21 January 2018

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PCNA is ubiquitinated by RNF8

21 January 2018

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Roles of sequential ubiquitination of PCNA in DNA-damage tolerance

21 January 2018

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Structure of monoubiquitinated PCNA: implications for DNA polymerase switching and Okazaki fragment maturation

21 January 2018

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A Protein Phosphatase-1-binding Motif Identified by the Panning of a Random Peptide Display Library

21 January 2018

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Characterization of human DNA polymerase delta and its subassemblies reconstituted by expression in the MultiBac system

21 January 2018

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Regulation of polymerase exchange between Poleta and Poldelta by monoubiquitination of PCNA and the movement of DNA polymerase holoenzyme

21 January 2018

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GINS is a DNA polymerase epsilon accessory factor during chromosomal DNA replication in budding yeast

21 January 2018

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The Influence of the Cdc27 Subunit on the Properties of theSchizosaccharomyces pombeDNA Polymerase δ

21 January 2018

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A Heterotrimeric PCNA in the Hyperthermophilic Archaeon Sulfolobus solfataricus

21 January 2018

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7 January 2021

The Pol32 Subunit of DNA Polymerase δ Contains Separable Domains for Processive Replication and Proliferating Cell Nuclear Antigen (PCNA) Binding

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7 January 2021

Structural and functional properties of calf thymus DNA polymerase delta

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7 January 2021

Immunochemical studies of DNA polymerase delta: relationships with DNA polymerase alpha

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7 January 2021

Evidence that errors made by DNA polymerase alpha are corrected by DNA polymerase delta

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7 January 2021

The Interdomain Connector Loop of Human PCNA Is Involved in a Direct Interaction with Human Polymerase δ

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7 January 2021

Identifiers

DOI

10.1002/EM.21743

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release_aw6lzd6hlnaxjp6soq2fycarju

27 August 2017

Fatcat ID

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Fatcat

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24 November 2022

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