The lysine48-based polyubiquitin chain proteasomal signal: not a single child anymore (Q38057666)

27 August 2017

title

The lysine48-based polyubiquitin chain proteasomal signal: not a single child anymore (English)

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27 August 2017

Aaron Ciechanover

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Yelena Kravtsova-Ivantsiv

27 August 2017

series ordinal

object named as

Yelena Kravtsova-Ivantsiv

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27 August 2017

Thomas Sommer

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27 August 2017

language of work or name

English

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publication date

4 November 2012

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Angewandte Chemie International Edition

27 August 2017

published in

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volume

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27 August 2017

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27 August 2017

page(s)

192-198

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https://api.crossref.org/works/10.1002%2FANIE.201205656

27 August 2017

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Nonproteolytic functions of ubiquitin in cell signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

The ubiquitin code of yeast permease trafficking.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

Recognition of the polyubiquitin proteolytic signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

A multiubiquitin chain is confined to specific lysine in a targeted short-lived protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

Proposed role of ATP in protein breakdown: conjugation of protein with multiple chains of the polypeptide of ATP-dependent proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

ATP-dependent conjugation of reticulocyte proteins with the polypeptide required for protein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

Ubiquitin degradation with its substrate, or as a monomer in a ubiquitination-independent mode, provides clues to proteasome regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

The size of the proteasomal substrate determines whether its degradation will be mediated by mono- or polyubiquitylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

Taf1 regulates Pax3 protein by monoubiquitination in skeletal muscle progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

Regulation of Pax3 by proteasomal degradation of monoubiquitinated protein in skeletal muscle progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

Non-canonical Wnt signaling induces ubiquitination and degradation of Syndecan4

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

Modification by single ubiquitin moieties rather than polyubiquitination is sufficient for proteasomal processing of the p105 NF-kappaB precursor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

APC/C-mediated multiple monoubiquitylation provides an alternative degradation signal for cyclin B1

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

Polyubiquitin linkage profiles in three models of proteolytic stress suggest the etiology of Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

Identification of a physiological E2 module for the human anaphase-promoting complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

UBE2S drives elongation of K11-linked ubiquitin chains by the anaphase-promoting complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

UBE2S elongates ubiquitin chains on APC/C substrates to promote mitotic exit

21 January 2018

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https://api.crossref.org/works/10.1002%2FANIE.201205656

K11-linked polyubiquitination in cell cycle control revealed by a K11 linkage-specific antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

Mechanism of ubiquitin-chain formation by the human anaphase-promoting complex

21 January 2018

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https://api.crossref.org/works/10.1002%2FANIE.201205656

K11-linked ubiquitin chains as novel regulators of cell division

21 January 2018

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https://api.crossref.org/works/10.1002%2FANIE.201205656

Quantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradation

21 January 2018

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https://api.crossref.org/works/10.1002%2FANIE.201205656

Lysine 63-linked polyubiquitin chain may serve as a targeting signal for the 26S proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

Certain pairs of ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s) synthesize nondegradable forked ubiquitin chains containing all possible isopeptide linkages.

21 January 2018

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https://api.crossref.org/works/10.1002%2FANIE.201205656

S5a promotes protein degradation by blocking synthesis of nondegradable forked ubiquitin chains

21 January 2018

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https://api.crossref.org/works/10.1002%2FANIE.201205656

SUMO playing tag with ubiquitin

21 January 2018

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https://api.crossref.org/works/10.1002%2FANIE.201205656

The SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition

21 January 2018

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https://api.crossref.org/works/10.1002%2FANIE.201205656

21 January 2018

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https://api.crossref.org/works/10.1002%2FANIE.201205656

Proteomics analysis of nucleolar SUMO-1 target proteins upon proteasome inhibition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

The ubiquitin-proteasome system is a key component of the SUMO-2/3 cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

Arsenic degrades PML or PML-RARalpha through a SUMO-triggered RNF4/ubiquitin-mediated pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

Arsenic trioxide stimulates SUMO-2/3 modification leading to RNF4-dependent proteolytic targeting of PML.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

SUMO-specific protease 1 is essential for stabilization of HIF1alpha during hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

Linear ubiquitination prevents inflammation and regulates immune signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

SHARPIN is a component of the NF-κB-activating linear ubiquitin chain assembly complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

A ubiquitin ligase complex assembles linear polyubiquitin chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

Distinct consequences of posttranslational modification by linear versus K63-linked polyubiquitin chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

Apoptosis induction by Bid requires unconventional ubiquitination and degradation of its N-terminal fragment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

Non-canonical ubiquitylation of the proneural protein Ngn2 occurs in both Xenopus embryos and mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

Ubiquitylation on canonical and non-canonical sites targets the transcription factor neurogenin for ubiquitin-mediated proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

Ubiquitination on nonlysine residues by a viral E3 ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

Ubiquitination of serine, threonine, or lysine residues on the cytoplasmic tail can induce ERAD of MHC-I by viral E3 ligase mK3

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

A novel site for ubiquitination: the N-terminal residue, and not internal lysines of MyoD, is essential for conjugation and degradation of the protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

Degradation of the Id2 developmental regulator: targeting via N-terminal ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

HSP70 protects BCL2L12 and BCL2L12A from N-terminal ubiquitination-mediated proteasomal degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

Ubiquitin proteasome-dependent degradation of the transcriptional coactivator PGC-1{alpha} via the N-terminal pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

N-terminal hemagglutinin tag renders lysine-deficient APOBEC3G resistant to HIV-1 Vif-induced degradation by reduced polyubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

Degradation of the epstein-barr virus latent membrane protein 1 (LMP1) by the ubiquitin-proteasome pathway. Targeting via ubiquitination of the N-terminal residue

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

Lysine-independent ubiquitination of Epstein-Barr virus LMP2A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

Impact of the N-terminal amino acid on targeted protein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

Processed N-termini of mature proteins in higher eukaryotes and their major contribution to dynamic proteomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

Signal-induced degradation of I kappa B alpha requires site-specific ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

Multiple C-terminal lysine residues target p53 for ubiquitin-proteasome-mediated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

A proteomics approach to understanding protein ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

A subset of membrane-associated proteins is ubiquitinated in response to mutations in the endoplasmic reticulum degradation machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

A systematic approach to the analysis of protein phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

Large-scale protein identification using mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

Preferred in vivo ubiquitination sites.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

Mass Spectrometric Analysis of Lysine Ubiquitylation Reveals Promiscuity at Site Level

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

Dual effects of IkappaB kinase beta-mediated phosphorylation on p105 Fate: SCF(beta-TrCP)-dependent degradation and SCF(beta-TrCP)-independent processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

Mutagenic analysis of the destruction signal of mitotic cyclins and structural characterization of ubiquitinated intermediates

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

Quantitative analysis of in vitro ubiquitinated cyclin B1 reveals complex chain topology

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201205656

Novel multiubiquitin chain linkages catalyzed by the conjugating enzymes E2EPF and RAD6 are recognized by 26 S proteasome subunit 5

21 January 2018

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/ANIE.201205656

Chemical approaches to angiogenesis

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/ANIE.201205656

The Polycomb Protein Ring1B Generates Self Atypical Mixed Ubiquitin Chains Required for Its In Vitro Histone H2A Ligase Activity

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/ANIE.201205656

Diverse polyubiquitin chains accumulate following 26S proteasomal dysfunction in mammalian neurones

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/ANIE.201205656

Ubiquitin/proteasome-mediated degradation of p19INK4d determines its periodic expression during the cell cycle

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1002/ANIE.201205656

Identifiers

DOI

10.1002/ANIE.201205656

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27 August 2017

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