Engineered riboswitches: Expanding researchers' toolbox with synthetic RNA regulators (Q38019711)

27 August 2017

title

Engineered riboswitches: Expanding researchers' toolbox with synthetic RNA regulators (English)

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27 August 2017

Beatrix Suess

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27 August 2017

Alexander Wittmann

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27 August 2017

language of work or name

English

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publication date

28 February 2012

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27 August 2017

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27 August 2017

volume

586

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27 August 2017

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27 August 2017

page(s)

2076-2083

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Synthetic biology: applications come of age

27 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Engineering a mevalonate pathway in Escherichia coli for production of terpenoids

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Production of the antimalarial drug precursor artemisinic acid in engineered yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Dispersing biofilms with engineered enzymatic bacteriophage

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Short hairpin RNA-expressing bacteria elicit RNA interference in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Nature, nurture, or chance: stochastic gene expression and its consequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Functional roles for noise in genetic circuits

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Noise in eukaryotic gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Regulation of noise in the expression of a single gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Programming gene expression with combinatorial promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Uncovering cis regulatory codes using synthetic promoter shuffling

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Engineered gene circuits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Mining logic gates in prokaryotic transcriptional regulation networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

A gene regulation system with four distinct expression levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

A universal RNAi-based logic evaluator that operates in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Destabilized green fluorescent protein for monitoring dynamic changes in yeast gene expression with flow cytometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Engineering controllable protein degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

A synthetic gene network for tuning protein degradation in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

A tunable genetic switch based on RNAi and repressor proteins for regulating gene expression in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Regulation of bacterial gene expression by riboswitches

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

The distributions, mechanisms, and structures of metabolite-binding riboswitches

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

The structural and functional diversity of metabolite-binding riboswitches

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Control of gene expression by a natural metabolite-responsive ribozyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

S-box and T-box riboswitches and antisense RNA control a sulfur metabolic operon of Clostridium acetobutylicum

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

In vitro selection of RNA molecules that bind specific ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Microfluidic selection and applications of aptamers

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Micromagnetic selection of aptamers in microfluidic channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Automation in the high-throughput selection of random combinatorial libraries--different approaches for select applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Adaptive recognition by nucleic acid aptamers

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Rational design of allosteric ribozymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Engineering precision RNA molecular switches

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Controlling gene expression in living cells through small molecule-RNA interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

A tetracycline-binding RNA aptamer

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Conditional gene expression by controlling translation with tetracycline-binding aptamers

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

A fast and efficient translational control system for conditional expression of yeast genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Screening for engineered neomycin riboswitches that control translation initiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Inducible regulation of the S. cerevisiae cell cycle mediated by an RNA aptamer-ligand complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Inhibition of translation by RNA-small molecule interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

An artificial riboswitch for controlling pre-mRNA splicing

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Tetracycline aptamer-controlled regulation of pre-mRNA splicing in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

A high-throughput screen for synthetic riboswitches reveals mechanistic insights into their function

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Guiding bacteria with small molecules and RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Reprogramming bacteria to seek and destroy an herbicide

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Synthetic riboswitches that induce gene expression in diverse bacterial species

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

A theophylline responsive riboswitch based on helix slipping controls gene expression in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Allosteric selection of ribozymes that respond to the second messengers cGMP and cAMP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Sequence elements outside the hammerhead ribozyme catalytic core enable intracellular activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Tertiary contacts distant from the active site prime a ribozyme for catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Exogenous control of mammalian gene expression through modulation of RNA self-cleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Identification of inhibitors of ribozyme self-cleavage in mammalian cells via high-throughput screening of chemical libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

A modular and extensible RNA-based gene-regulatory platform for engineering cellular function

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Genetic control of mammalian T-cell proliferation with synthetic RNA regulatory systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Artificial riboswitches: synthetic mRNA-based regulators of gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

A ligand-dependent hammerhead ribozyme switch for controlling mammalian gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Selection of tetracycline inducible self-cleaving ribozymes as synthetic devices for gene regulation in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Direct selection for ribozyme cleavage activity in cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

In vivo evolution of an RNA-based transcriptional activator

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

In vivo evolution of an RNA-based transcriptional silencing domain in S. cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Engineering a ligand-dependent RNA transcriptional activator

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

An RNA aptamer that induces transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Mechanistic basis for RNA aptamer-based induction of TetR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Rational design of a small molecule-responsive intramer controlling transgene expression in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Mechanistic insights into an engineered riboswitch: a switching element which confers riboswitch activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Highly modular structure and ligand binding by conformational capture in a minimalistic riboswitch

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

PELDOR spectroscopy reveals preorganization of the neomycin-responsive riboswitch tertiary structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Molecular analysis of a synthetic tetracycline-binding riboswitch

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Structural Basis for Specific, High-Affinity Tetracycline Binding by an In Vitro Evolved Aptamer and Artificial Riboswitch

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Thermodynamic characterization of an engineered tetracycline-binding riboswitch

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Ligand-induced conformational capture of a synthetic tetracycline riboswitch revealed by pulse EPR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Conformational dynamics of the tetracycline-binding aptamer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

A FACS-based approach to engineering artificial riboswitches

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

A flow cytometry-based screen for synthetic riboswitches

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Random walks to synthetic riboswitches--a high-throughput selection based on cell motility.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Engineering complex riboswitch regulation by dual genetic selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

Fast Cleavage Kinetics of a Natural Hammerhead Ribozyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2012.02.038

10.1016/J.FEBSLET.2012.02.038

21 January 2018

Identifiers

DOI

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27 August 2017

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