Induction of the human cathelicidin LL-37 as a novel treatment against bacterial infections (Q38018928)

27 August 2017

title

Induction of the human cathelicidin LL-37 as a novel treatment against bacterial infections (English)

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27 August 2017

Birgitta Agerberth

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author name string

Anne M van der Does

series ordinal

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27 August 2017

Peter Bergman

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27 August 2017

Lennart Lindbom

series ordinal

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27 August 2017

language of work or name

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13 June 2012

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Journal of Leukocyte Biology

27 August 2017

published in

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27 August 2017

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27 August 2017

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27 August 2017

page(s)

735-742

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Pathogens resistant to antibacterial agents

27 August 2017

cites work

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https://api.crossref.org/works/10.1189%2FJLB.0412178

Antimicrobial peptides: general overview and clinical implications in human health and disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Antimicrobial peptides: natural effectors of the innate immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

AMPed up immunity: how antimicrobial peptides have multiple roles in immune defense

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Antimicrobial peptides of multicellular organisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Designing antimicrobial peptides: form follows function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Diversity of antimicrobial peptides and their mechanisms of action

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Alternative mechanisms of action of cationic antimicrobial peptides on bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Potential of immunomodulatory host defense peptides as novel anti-infectives

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Human cathelicidin, hCAP-18, is processed to the antimicrobial peptide LL-37 by extracellular cleavage with proteinase 3

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Kallikrein-mediated proteolysis regulates the antimicrobial effects of cathelicidins in skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Cathelicidin LL-37: a multitask antimicrobial peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

The roles of cathelicidin LL-37 in immune defences and novel clinical applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

The role of the multifunctional peptide LL-37 in host defense

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Bacterial products increase expression of the human cathelicidin hCAP-18/LL-37 in cultured human sinus epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Cutting edge: 1,25-dihydroxyvitamin D3 is a direct inducer of antimicrobial peptide gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Histone-deacetylase inhibitors induce the cathelicidin LL-37 in gastrointestinal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

PU.1 and bacterial metabolites regulate the human gene CAMP encoding antimicrobial peptide LL-37 in colon epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Expression and secretion of cathelicidin LL-37 in human epithelial cells after infection by Mycobacterium bovis Bacillus Calmette-Guérin

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Regulation of cathelicidin antimicrobial peptide expression by an endoplasmic reticulum (ER) stress signaling, vitamin D receptor-independent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Neisseria gonorrhoeae downregulates expression of the human antimicrobial peptide LL-37.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Bacterial exotoxins downregulate cathelicidin (hCAP-18/LL-37) and human beta-defensin 1 (HBD-1) expression in the intestinal epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Effects of the cathelicidin LL-37 on intestinal epithelial barrier integrity

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Human beta defensin 2 promotes intestinal wound healing in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Human endogenous antibiotic LL-37 stimulates airway epithelial cell proliferation and wound closure

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Cathelicidin LL-37 increases lung epithelial cell stiffness, decreases transepithelial permeability, and prevents epithelial invasion by Pseudomonas aeruginosa.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

The human cathelicidin LL-37 preferentially promotes apoptosis of infected airway epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

The antimicrobial peptide LL-37 activates innate immunity at the airway epithelial surface by transactivation of the epidermal growth factor receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

The human antimicrobial peptide LL-37 is a multifunctional modulator of innate immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

The human antimicrobial peptide LL-37 suppresses apoptosis in keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

An antimicrobial cathelicidin peptide, human CAP18/LL-37, suppresses neutrophil apoptosis via the activation of formyl-peptide receptor-like 1 and P2X7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

The host defense peptide LL-37 selectively permeabilizes apoptotic leukocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Secondary necrosis of apoptotic neutrophils induced by the human cathelicidin LL-37 is not proinflammatory to phagocytosing macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Neutrophil secondary necrosis is induced by LL-37 derived from cathelicidin

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

The antimicrobial peptide LL-37 modulates the inflammatory and host defense response of human neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Modulation of the TLR-mediated inflammatory response by the endogenous human host defense peptide LL-37.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Intracellular receptor for human host defense peptide LL-37 in monocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

The anti-microbial peptide LL-37 inhibits the activation of dendritic cells by TLR ligands.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Selective killing of vaccinia virus by LL-37: implications for eczema vaccinatum

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Innate antimicrobial peptide protects the skin from invasive bacterial infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Cathelicidin-deficient (Cnlp -/- ) mice show increased susceptibility to Pseudomonas aeruginosa keratitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

The antimicrobial peptide cathelicidin protects the urinary tract against invasive bacterial infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Cathelicidin mediates innate intestinal defense against colonization with epithelial adherent bacterial pathogens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Effects of bacterial infection on airway antimicrobial peptides and proteins in COPD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Antiviral activity and increased host defense against influenza infection elicited by the human cathelicidin LL-37

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

LL37 and cationic peptides enhance TLR3 signaling by viral double-stranded RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Anti-fungal activity of cathelicidins and their potential role in Candida albicans skin infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Endogenous antimicrobial peptides and skin infections in atopic dermatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Phenylbutyrate induces antimicrobial peptide expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Battle and balance at mucosal surfaces--the story of Shigella and antimicrobial peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Phenylbutyrate counteracts Shigella mediated downregulation of cathelicidin in rabbit lung and intestinal epithelia: a potential therapeutic strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Histone acetylation in keratinocytes enables control of the expression of cathelicidin and CD14 by 1,25-dihydroxyvitamin D3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Sodium butyrate up-regulates cathelicidin gene expression via activator protein-1 and histone acetylation at the promoter region in a human lung epithelial cell line, EBC-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Vitamin D: modulator of the immune system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Vitamin D metabolism and signaling in the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Vitamin D3: a helpful immuno-modulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Characterization of 1 alpha-hydroxylation of vitamin D3 sterols by cultured alveolar macrophages from patients with sarcoidosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

IL-15 links TLR2/1-induced macrophage differentiation to the vitamin D-dependent antimicrobial pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Regulation of the CAMP gene by 1,25(OH)2D3 in various tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Human cathelicidin antimicrobial peptide (CAMP) gene is a direct target of the vitamin D receptor and is strongly up-regulated in myeloid cells by 1,25-dihydroxyvitamin D3

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Convergence of IL-1beta and VDR activation pathways in human TLR2/1-induced antimicrobial responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Induction of cathelicidin in normal and CF bronchial epithelial cells by 1,25-dihydroxyvitamin D(3).

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Vitamin D as an inducer of cathelicidin antimicrobial peptide expression: past, present and future

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Enhanced translocation of bacteria across metabolically stressed epithelia is reduced by butyrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Improved outcome in shigellosis associated with butyrate induction of an endogenous peptide antibiotic

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Novel role of the vitamin D receptor in maintaining the integrity of the intestinal mucosal barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Histone deacetylase inhibitor, butyrate, attenuates lipopolysaccharide-induced acute lung injury in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Topical treatment with the vitamin D analogue calcipotriol enhances the upregulation of the antimicrobial protein hCAP18/LL-37 during wounding in human skin in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Effects of short chain fatty acids on effector mechanisms of neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

1α,25-Dihydroxyvitamin D₃ inhibits neutrophil recruitment in hamster model of acute lung injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Decreased anti-inflammatory responses to vitamin D in neonatal neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Butyrate inhibits inflammatory responses through NFkappaB inhibition: implications for Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Cutting edge: vitamin D-mediated human antimicrobial activity against Mycobacterium tuberculosis is dependent on the induction of cathelicidin

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Vitamin D3 induces autophagy in human monocytes/macrophages via cathelicidin

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Butyrate affects differentiation, maturation and function of human monocyte-derived dendritic cells and macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Essential role of the JAK/STAT1 signaling pathway in the expression of inducible nitric-oxide synthase in intestinal epithelial cells and its regulation by butyrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Butyrate inhibits functional differentiation of human monocyte-derived dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

1 Alpha,25-dihydroxyvitamin D3 inhibits differentiation, maturation, activation, and survival of dendritic cells leading to impaired alloreactive T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

1alpha,25-Dihydroxyvitamin D3-induced monocyte antimycobacterial activity is regulated by phosphatidylinositol 3-kinase and mediated by the NADPH-dependent phagocyte oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Control of cutaneous antimicrobial peptides by vitamin D3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Antimicrobial peptides and self-DNA in autoimmune skin inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Beta-defensins and LL-37 in bronchoalveolar lavage fluid of patients with cystic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

Emerging roles of the host defense peptide LL-37 in human cancer and its potential therapeutic applications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

The role of antimicrobial peptides in cardiovascular physiology and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1189%2FJLB.0412178

21 January 2018

Identifiers

DOI

10.1189/JLB.0412178

1 reference

27 August 2017

1 reference