Branched and linear poly(ethylene imine)-based conjugates: synthetic modification, characterization, and application (Q38014754)

27 August 2017

title

Branched and linear poly(ethylene imine)-based conjugates: synthetic modification, characterization, and application (English)

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27 August 2017

Stephanie Schubert

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Michael Jäger

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Ulrich S Schubert

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Sofia Ochrimenko

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27 August 2017

Dagmar Fischer

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27 August 2017

language of work or name

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30 May 2012

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27 August 2017

published in

Chemical Society Reviews

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27 August 2017

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27 August 2017

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27 August 2017

page(s)

4755-4767

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Polymers for drug delivery systems

27 August 2017

cites work

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Different strategies for formation of pegylated EGF-conjugated PEI/DNA complexes for targeted gene delivery

21 January 2018

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Poly(beta-amino ester) and cationic phospholipid-based lipopolyplexes for gene delivery and transfection in human aortic endothelial and smooth muscle cells

21 January 2018

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Characteristics of DEAE-dextran-MMA graft copolymer as a nonviral gene carrier

21 January 2018

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Maltose- and maltotriose-modified, hyperbranched poly(ethylene imine)s (OM-PEIs): Physicochemical and biological properties of DNA and siRNA complexes

21 January 2018

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Mechanistic investigation of poly(ethylene imine)-based siRNA delivery: disulfide bonds boost intracellular release of the cargo

21 January 2018

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Nonviral vectors for gene delivery

21 January 2018

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Recent advances in rational gene transfer vector design based on poly(ethylene imine) and its derivatives

21 January 2018

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A two-stage poly(ethylenimine)-mediated cytotoxicity: implications for gene transfer/therapy

21 January 2018

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Design and development of polymers for gene delivery

21 January 2018

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Toxicity pathway focused gene expression profiling of PEI-based polymers for pulmonary applications

21 January 2018

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In vitro cytotoxicity testing of polycations: influence of polymer structure on cell viability and hemolysis

21 January 2018

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Linear topology confers in vivo gene transfer activity to polyethylenimines

21 January 2018

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Tumor-targeted gene therapy: strategies for the preparation of ligand-polyethylene glycol-polyethylenimine/DNA complexes

21 January 2018

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Characterization of lactoferrin as a targeting ligand for nonviral gene delivery to airway epithelial cells

21 January 2018

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HER2 targeted polyplexes: the effect of polyplex composition and conjugation chemistry on in vitro and in vivo characteristics

21 January 2018

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Low molecular weight polyethylenimine cross-linked by 2-hydroxypropyl-gamma-cyclodextrin coupled to peptide targeting HER2 as a gene delivery vector.

21 January 2018

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https://api.crossref.org/works/10.1039%2FC2CS35146C

Trastuzumab-polyethylenimine-polyethylene glycol conjugates for targeting Her2-expressing tumors.

21 January 2018

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https://api.crossref.org/works/10.1039%2FC2CS35146C

A ligand-mediated nanovector for targeted gene delivery and transfection in cancer cells

21 January 2018

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https://api.crossref.org/works/10.1039%2FC2CS35146C

Full deacylation of polyethylenimine dramatically boosts its gene delivery efficiency and specificity to mouse lung

21 January 2018

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https://api.crossref.org/works/10.1039%2FC2CS35146C

Poly(ethylenimine) and its role in gene delivery

21 January 2018

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https://api.crossref.org/works/10.1039%2FC2CS35146C

Polymers and nanoparticles: intelligent tools for intracellular targeting?

21 January 2018

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https://api.crossref.org/works/10.1039%2FC2CS35146C

Low-molecular-weight polyethylenimine as a non-viral vector for DNA delivery: comparison of physicochemical properties, transfection efficiency and in vivo distribution with high-molecular-weight polyethylenimine

21 January 2018

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https://api.crossref.org/works/10.1039%2FC2CS35146C

A novel non-viral vector for DNA delivery based on low molecular weight, branched polyethylenimine: effect of molecular weight on transfection efficiency and cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

Exploring polyethylenimine-mediated DNA transfection and the proton sponge hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

Inhibition of monocyte adhesion on brain-derived endothelial cells by NF-kappaB decoy/polyethylenimine complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

Dendritic polyamines: simple access to new materials with defined treelike structures for application in nonviral gene delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

Living ring-opening polymerization of N-sulfonylaziridines: synthesis of high molecular weight linear polyamines

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

Recent syntheses and reactions of cyclic imidic esters

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

Synthesis of linear polyethylenimine derivatives for DNA transfection

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

Enzymatic degradation of PLLA-PEOz-PLLA triblock copolymers

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

Poly(ethylenimine-co-L-lactamide-co-succinamide): a biodegradable polyethylenimine derivative with an advantageous pH-dependent hydrolytic degradation for gene delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

Tandem mass spectrometry of poly(ethylene imine)s by electrospray ionization (ESI) and matrix-assisted laser desorption/ionization (MALDI).

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

Effect of polyethylene glycol on gene delivery of polyethylenimine

21 January 2018

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https://api.crossref.org/works/10.1039%2FC2CS35146C

A degradable polyethylenimine derivative with low toxicity for highly efficient gene delivery.

21 January 2018

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https://api.crossref.org/works/10.1039%2FC2CS35146C

Integrin targeting using RGD-PEI conjugates for in vitro gene transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

Specific systemic nonviral gene delivery to human hepatocellular carcinoma xenografts in SCID mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

Biodegradable poly(ethylenimine) for plasmid DNA delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

Cross-linked small polyethylenimines: while still nontoxic, deliver DNA efficiently to mammalian cells in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

Self-assembly of polyamine-poly(ethylene glycol) copolymers with phosphorothioate oligonucleotides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

Partial acetylation of polyethylenimine enhances in vitro gene delivery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

Enhancing polyethylenimine's delivery of plasmid DNA into mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

Novel shielded transferrin-polyethylene glycol-polyethylenimine/DNA complexes for systemic tumor-targeted gene transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

Glucosylated polyethylenimine as a tumor-targeting gene carrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

Drug delivery strategy utilizing conjugation via reversible disulfide linkages: role and site of cellular reducing activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

LHRH receptor-mediated delivery of siRNA using polyelectrolyte complex micelles self-assembled from siRNA-PEG-LHRH conjugate and PEI.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

Cyclodextrin-polyethylenimine conjugates for targeted in vitro gene delivery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

Biotinylated transferrin/avidin/biotinylated disulfide containing PEI bioconjugates mediated p53 gene delivery system for tumor targeted transfection

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

Targeted delivery of complexes of biotin-PEG-polyethylenimine and NF-kappaB decoys to brain-derived endothelial cells in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

Cyclodextrin-PEI-Tat Polymer as a Vector for Plasmid DNA Delivery to Placenta Mesenchymal Stem Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

Low molecular weight polyethylenimines linked by beta-cyclodextrin for gene transfer into the nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

Chitosan-graft-(PEI-β-cyclodextrin) copolymers and their supramolecular PEGylation for DNA and siRNA delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

RGD conjugation to polyethyleneimine does not improve DNA delivery to bone marrow stromal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

Monoclonal antibody-polyethyleneimine conjugates targeting Her-2/neu or CD90 allow cell type-specific nonviral gene delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

Biomimetic polymers in pharmaceutical and biomedical sciences.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

Gene transfer with synthetic virus-like particles via the integrin-mediated endocytosis pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

Dual-targeting non-viral vector based on polyethylenimine improves gene transfer efficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

Efficient polyethylenimine-mediated gene delivery proceeds via a caveolar pathway in HeLa cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

Identification and characterization of a novel peptide ligand of epidermal growth factor receptor for targeted delivery of therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

Targeting of the beta(2)-adrenoceptor increases nonviral gene delivery to pulmonary epithelial cells in vitro and lungs in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

Receptor-targeted gene delivery via folate-conjugated polyethylenimine

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

Hyaluronic acid-polyethyleneimine conjugate for target specific intracellular delivery of siRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

Uronic acids functionalized polyethyleneimine (PEI)-polyethyleneglycol (PEG)-graft-copolymers as novel synthetic gene carriers

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

Targeting of the prostacyclin specific IP1 receptor in lungs with molecular conjugates comprising prostaglandin I2 analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

In Vitro Gene Delivery to Hepatocytes with Galactosylated Polyethylenimine

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

Mannose polyethylenimine conjugates for targeted DNA delivery into dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

Integrin alphaVbeta3 targeted gene delivery using RGD peptidomimetic conjugates with copolymers of PEGylated poly(ethylene imine).

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

Folate receptor-mediated intracellular delivery of recombinant caspase-3 for inducing apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

Conjugation of a new two-photon fluorophore to poly(ethylenimine) for gene delivery imaging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

The labelling of proteins to high specific radioactivities by conjugation to a 125I-containing acylating agent. Application to the radioimmunoassay

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

Importance of lateral and steric stabilization of polyelectrolyte gene delivery vectors for extended systemic circulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

Effect of pegylation on pharmaceuticals

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

PEGylated DNA/transferrin-PEI complexes: reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

Low molecular weight linear polyethylenimine-b-poly(ethylene glycol)-b-polyethylenimine triblock copolymers: synthesis, characterization, and in vitro gene transfer properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

Chemoselectivity and the curious reactivity preferences of functional groups

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

Visualization of the degradation of a disulfide polymer, linear poly(ethylenimine sulfide), for gene delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

omega-Hydrazino linear polyethylenimine: a monoconjugation building block for nucleic acid delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

Linear Poly(ethylene imine)s by Acidic Hydrolysis of Poly(2-oxazoline)s: Kinetic Screening, Thermal Properties, and Temperature-Induced Solubility Transitions

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

The influence of cyclodextrin modification on cellular uptake and transfection efficiency of polyplexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

Click Chemistry beyond Metal-Catalyzed Cycloaddition

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

The Macrostopper Route: A New Synthesis Concept Leading Exclusively to Diblock Copolymers with Enhanced DNA Condensation Potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35146C

21 January 2018

Identifiers

DOI

10.1039/C2CS35146C

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27 August 2017

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