Pathways for bone loss in inflammatory disease (Q38004935)

26 August 2017

title

Pathways for bone loss in inflammatory disease (English)

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26 August 2017

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Georg Schett

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26 August 2017

Tobias Braun

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26 August 2017

publication date

1 June 2012

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Current osteoporosis reports

26 August 2017

published in

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26 August 2017

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26 August 2017

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26 August 2017

page(s)

101-108

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Positive regulators of osteoclastogenesis and bone resorption in rheumatoid arthritis

26 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

Evidence for osteocyte regulation of bone homeostasis through RANKL expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

Cytokine mRNA profiling identifies B cells as a major source of RANKL in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

Rituximab abrogates joint destruction in rheumatoid arthritis by inhibiting osteoclastogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

Deficiency of foxp3 regulatory T cells exacerbates autoimmune arthritis by altering the synovial proportions of CD4 T cells and dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

Staphylococcus aureus protein A binds to osteoblasts and triggers signals that weaken bone in osteomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

Bone destruction by receptor activator of nuclear factor κB ligand-expressing T cells in chronic gouty arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

Radiographic bone damage in chronic gout is negatively associated with the inflammatory cytokines soluble interleukin 6 receptor and osteoprotegerin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

L-type Ca2+ channel agonist inhibits RANKL-induced osteoclast formation via NFATc1 down-regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

Exogenous regucalcin stimulates osteoclastogenesis and suppresses osteoblastogenesis through NF-κB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

SPA0355, a thiourea analogue, inhibits inflammatory responses and joint destruction in fibroblast‐like synoviocytes and mice with collagen‐induced arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

Defective nuclear factor-κB-inducing kinase in aly/aly mice prevents bone resorption induced by local injection of lipopolysaccharide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

The large zinc finger protein ZAS3 is a critical modulator of osteoclastogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

Role of the A20-TRAF6 Axis in Lipopolysaccharide-mediated Osteoclastogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

Mouse Rankl Expression Is Regulated in T Cells by c-Fos through a Cluster of Distal Regulatory Enhancers Designated the T Cell Control Region

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

Elevated cytokine production restores bone resorption by human Btk-deficient osteoclasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

The Bruton tyrosine kinase inhibitor PCI-32765 ameliorates autoimmune arthritis by inhibition of multiple effector cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

Adenylate cyclase and calmodulin-dependent kinase have opposite effects on osteoclastogenesis by regulating the PKA-NFATc1 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

Acid sphingomyelinase regulates osteoclastogenesis by modulating sphingosine kinases downstream of RANKL signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

Erk1 positively regulates osteoclast differentiation and bone resorptive activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

Epigenetic regulation of osteoclast differentiation: possible involvement of Jmjd3 in the histone demethylation of Nfatc1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

Inhibitors of histone deacetylases in class I and class II suppress human osteoclasts in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

RANKL induces NFATc1 acetylation and stability via histone acetyltransferases during osteoclast differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

M-CSF potently augments RANKL-induced resorption activation in mature human osteoclasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

Anti-c-Fms antibody inhibits lipopolysaccharide-induced osteoclastogenesis in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

The Critical Role of IL-34 in Osteoclastogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

Interleukin 34 expression is associated with synovitis severity in rheumatoid arthritis patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

Direct Inhibition of Human RANK+ Osteoclast Precursors Identifies a Homeostatic Function of IL-1β

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

Complement C3a and C5a modulate osteoclast formation and inflammatory response of osteoblasts in synergism with IL-1β.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

Bone morphogenetic protein 6-induced interleukin-1β expression in macrophages requires PU.1/Smad1 interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

Interleukin-33 is expressed in differentiated osteoblasts and blocks osteoclast formation from bone marrow precursor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

Interleukin-33, a target of parathyroid hormone and oncostatin m, increases osteoblastic matrix mineral deposition and inhibits osteoclast formation in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

IL-33 shifts the balance from osteoclast to alternatively activated macrophage differentiation and protects from TNF-alpha-mediated bone loss.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

JAK2 is an important signal transducer in IL-33-induced NF-κB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

The Dual Function Cytokine IL-33 Interacts with the Transcription Factor NF-κB To Dampen NF-κB–Stimulated Gene Transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

IL-33 is expressed in human osteoblasts, but has no direct effect on bone remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

Measurement of interleukin-33 (IL-33) and IL-33 receptors (sST2 and ST2L) in patients with rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

Distinct serum and synovial fluid interleukin (IL)-33 levels in rheumatoid arthritis, psoriatic arthritis and osteoarthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

The tumor necrosis factor type 2 receptor plays a protective role in tumor necrosis factor-α-induced bone resorption lacunae on mouse calvariae

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

TNFα inhibits the development of osteoclasts through osteoblast-derived GM-CSF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

Primary human bone marrow adipocytes support TNF-α-induced osteoclast differentiation and function through RANKL expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

TNF activates calcium–nuclear factor of activated T cells (NFAT)c1 signaling pathways in human macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

Repair of bone erosions in rheumatoid arthritis treated with tumour necrosis factor inhibitors is based on bone apposition at the base of the erosion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

Dose-specific effects of tumor necrosis factor alpha on osteogenic differentiation of mesenchymal stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

Expression of POEM, a positive regulator of osteoblast differentiation, is suppressed by TNF-α

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

Intercellular adhesion molecule-1 on synovial cells attenuated interleukin-6-induced inhibition of osteoclastogenesis induced by receptor activator for nuclear factor κB ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

Wnt3a regulates tumor necrosis factor-α-stimulated interleukin-6 release in osteoblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

AMP-activated protein kinase regulates PDGF-BB-stimulated interleukin-6 synthesis in osteoblasts: involvement of mitogen-activated protein kinases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

IL-6 production is positively regulated by two distinct Src homology domain 2-containing tyrosine phosphatase-1 (SHP-1)-dependent CCAAT/enhancer-binding protein β and NF-κB pathways and an SHP-1-independent NF-κB pathway in lipopolysaccharide-stimul

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

Interleukin‐15 Induces Interleukin‐17 Production by Synovial T Cell Lines from Patients with Rheumatoid Arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

Mast cells express IL-17A in rheumatoid arthritis synovium

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

IL-17 increases cadherin-11 expression in a model of autoimmune experimental arthritis and in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

Interleukin-17A induces cathepsin K and MMP-9 expression in osteoclasts via celecoxib-blocked prostaglandin E2 in osteoblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

IL-17RA signaling amplifies antibody-induced arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

Anti-CXCL5 therapy ameliorates IL-17-induced arthritis by decreasing joint vascularization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

Enhanced Th17-cell responses render CCR2-deficient mice more susceptible for autoimmune arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

NF-κB signaling participates in both RANKL- and IL-4-induced macrophage fusion: receptor cross-talk leads to alterations in NF-κB pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

Interleukin‐4 inhibits RANKL‐induced NFATc1 expression via STAT6: A novel mechanism mediating its blockade of osteoclastogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

Phosphatidylserine-containing liposomes suppress inflammatory bone loss by ameliorating the cytokine imbalance provoked by infiltrated macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

Locally administered interferon-γ accelerates lipopolysaccharide-induced osteoclastogenesis independent of immunohistological RANKL upregulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

Molecular mechanisms of the biphasic effects of interferon-γ on osteoclastogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

Regulation of RANKL-induced osteoclastogenesis by TGF-β through molecular interaction between Smad3 and Traf6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

IL-15 promotes osteoclastogenesis via the PLD pathway in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

The influence of interleukin-32γ on osteoclastogenesis with a focus on fusion-related genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

Local expression of interleukin-27 ameliorates collagen-induced arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

Interleukin-19 blockade attenuates collagen-induced arthritis in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

Interleukin-20 antibody is a potential therapeutic agent for experimental arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

Anti–IL-20 monoclonal antibody inhibits the differentiation of osteoclasts and protects against osteoporotic bone loss

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

Interleukin-21 promotes osteoclastogenesis in humans with rheumatoid arthritis and in mice with collagen-induced arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

JNK1 controls mast cell degranulation and IL-1{beta} production in inflammatory arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

A microRNA expression signature of osteoclastogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

Anti IL-17A therapy inhibits bone loss in TNF-α-mediated murine arthritis by modulation of the T-cell balance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

Increased expression of interleukin-22 by synovial Th17 cells during late stages of murine experimental arthritis is controlled by interleukin-1 and enhances bone degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

Essential role of microRNA-155 in the pathogenesis of autoimmune arthritis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11914-012-0104-5

Osteocyte apoptosis regulates osteoclast precursor adhesion via osteocytic IL-6 secretion and endothelial ICAM-1 expression

21 January 2018

1 reference

12 December 2020

The inhibitory effect of microRNA-146a expression on bone destruction in collagen-induced arthritis

1 reference

12 December 2020

Angiotensin II induces interleukin-6 synthesis in osteoblasts through ERK1/2 pathway via AT1 receptor

1 reference

12 December 2020

Depth and volume of resorption induced by osteoclasts generated in the presence of RANKL, TNF-alpha/IL-1 or LIGHT

1 reference

12 December 2020

TSG-6 inhibits osteoclast activity via an autocrine mechanism and is functionally synergistic with osteoprotegerin

1 reference

12 December 2020

Th17 cells, not IL-17+ γδ T cells, drive arthritic bone destruction in mice and humans

1 reference

12 December 2020

IFN-γ directly inhibits TNF-α-induced osteoclastogenesis in vitro and in vivo and induces apoptosis mediated by Fas/Fas ligand interactions

1 reference

12 December 2020

Vitamin D receptor regulates TNF-mediated arthritis

1 reference

12 December 2020

Proteasome inhibition aggravates tumor necrosis factor-mediated bone resorption in a mouse model of inflammatory arthritis

1 reference

12 December 2020

Transgenic over-expression of interleukin-33 in osteoblasts results in decreased osteoclastogenesis

1 reference

12 December 2020

Osteoprotegerin expression in bone marrow by treatment with tocilizumab in rheumatoid arthritis

1 reference

12 December 2020

IL-27 suppresses RANKL expression in CD4+ T cells in part through STAT3

1 reference

12 December 2020

Interleukin-22 promotes osteoclastogenesis in rheumatoid arthritis through induction of RANKL in human synovial fibroblasts

1 reference

12 December 2020

Destructive role of myeloid differentiation factor 88 and protective role of TRIF in interleukin-17-dependent arthritis in mice

1 reference

12 December 2020

Receptor activator of nuclear factor kappa B ligand serum and synovial fluid level. A comparative study between rheumatoid arthritis and osteoarthritis

1 reference

12 December 2020

Orai1-mediated calcium entry plays a critical role in osteoclast differentiation and function by regulating activation of the transcription factor NFATc1

1 reference

12 December 2020

Involvement of IL-33 in the pathogenesis of rheumatoid arthritis: the effect of etanercept on the serum levels of IL-33.

1 reference

12 December 2020

The transcription factor FBI‐1/OCZF/LRF is expressed in osteoclasts and regulates RANKL‐induced osteoclast formation in vitro and in vivo

1 reference

12 December 2020

Interleukin-6 and soluble interleukin-6 receptor suppress osteoclastic differentiation by inducing PGE2 production in chondrocytes

1 reference

12 December 2020

Changes and significance of IL-25 in chicken collagen II-induced experimental arthritis (CIA)

1 reference

12 December 2020

Early effects of IL-6 receptor inhibition on bone homeostasis: a pilot study in women with rheumatoid arthritis.

1 reference

12 December 2020

T cell-mediated increased osteoclast formation from peripheral blood as a mechanism for Crohn's disease-associated bone loss

1 reference

12 December 2020

10.1007/S11914-012-0104-5

Identifiers

DOI

1 reference

Dimensions Publication ID

26 August 2017

1029524096

0 references

1 reference