The many faces of insulin-like peptide signalling in the brain (Q37994953)

SUMOylation mediates the nuclear translocation and signaling of the IGF-1 receptor

31 March 2020

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Characterization of a Drosophila protein that binds both epidermal growth factor and insulin-related growth factors

31 March 2020

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IGF-binding proteins--the pieces are falling into place.

31 March 2020

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Insulin-like growth factor I-immunoreactive peptide in adult human cerebellar Purkinje cells: co-localization with low-affinity nerve growth factor receptor

31 March 2020

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Insulin-like growth factor I mRNA levels are developmentally regulated in specific regions of the rat brain

31 March 2020

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Expression of somatomedin/insulin-like growth factor messenger ribonucleic acids in the human fetus: identification, characterization, and tissue distribution

31 March 2020

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Dissociation of IGF2 and H19 imprinting in human brain

31 March 2020

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The expression of insulin-like growth factor I and insulin-like growth factor II genes in the human fetal and adult brain and in glioma

31 March 2020

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Patterns of insulin-like growth factor and IGF receptor gene expression in the brain. Functional implications

31 March 2020

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Expression of the insulin-like growth factor II gene in the choroid plexus and the leptomeninges of the adult rat central nervous system

31 March 2020

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The source of cerebral insulin

31 March 2020

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The hypothalamus and ß-cell connection in the gene-targeting era.

31 March 2020

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Insulin-like growth factor-1 mRNA is increased in deafferented hippocampus: spatiotemporal correspondence of a trophic event with axon sprouting

31 March 2020

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Coordinate IGF-I and IGFBP5 gene expression in perinatal rat brain after hypoxia-ischemia

31 March 2020

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Characterization of insulin-like growth factor binding proteins produced in the rat central nervous system

31 March 2020

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Cellular actions of the insulin-like growth factor binding proteins

31 March 2020

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IGF-binding protein mRNAs in the human fetus: tissue and cellular distribution of developmental expression

31 March 2020

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Localization of insulin-like growth factor binding protein-2 messenger RNA during postnatal brain development: Correlation with insulin-like growth factors I and II

31 March 2020

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Expression of insulin-like growth factor binding protein-4 and -5 mRNAs in adult rat forebrain

31 March 2020

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Localization of insulin‐like growth factor binding protein‐4 expression in the developing and adult rat brain: Analysis by in situ hybridization

31 March 2020

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Correlation between insulin-like growth factor (IGF)-binding protein 5 and IGF-I gene expression during brain development.

31 March 2020

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Methyl CpG-binding protein 2 (a mutation of which causes Rett syndrome) directly regulates insulin-like growth factor binding protein 3 in mouse and human brains

31 March 2020

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Depolarization induces insulin-like growth factor binding protein-2 expression in vivo via NMDA receptor stimulation

31 March 2020

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Cytokines regulate IGF binding proteins in the cns

31 March 2020

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Transient IGF-I gene expression during the maturation of functionally related central projection neurons

31 March 2020

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Insulin-Like Growth Factor II Messenger Ribonucleic Acids are Synthesized in the Choroid Plexus of the Rat Brain

31 March 2020

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Expression of IGF-I and insulin receptor genes in the rat central nervous system: a developmental, regional, and cellular analysis.

31 March 2020

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Insulin and insulin-like growth factor receptors in the nervous system

31 March 2020

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Cellular pattern of insulin-like growth factor-I (IGF-I) and type I IGF receptor gene expression in early organogenesis: comparison with IGF-II gene expression

31 March 2020

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Developmental expression of insulin-like growth factor-II receptor immunoreactivity in the rat central nervous system

31 March 2020

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Ontogeny of insulin-like growth factor I, its receptor, and its binding proteins in the rat hypothalamus

31 March 2020

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The role of insulin and insulin-like growth factor I in the molecular and cellular mechanisms underlying the pathology of Alzheimer's disease

31 March 2020

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The insulin-like growth factor-II/mannose-6-phosphate receptor: structure, distribution and function in the central nervous system

31 March 2020

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Localization of the insulin-like growth factor I receptor in the cerebellum and hypothalamus of adult rats: an electron microscopic study

31 March 2020

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Single transmembrane domain insulin-like growth factor-II/mannose-6-phosphate receptor regulates central cholinergic function by activating a G-protein-sensitive, protein kinase C-dependent pathway

31 March 2020

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Different mechanisms are involved in intracellular calcium increase by insulin-like growth factors 1 and 2 in articular chondrocytes: voltage-gated calcium channels, and/or phospholipase C coupled to a pertussis-sensitive G-protein

31 March 2020

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Integrative neurobiology of energy homeostasis-neurocircuits, signals and mediators

31 March 2020

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Saturable transport of insulin from plasma into the central nervous system of dogs in vivo. A mechanism for regulated insulin delivery to the brain

31 March 2020

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Circulating insulin-like growth factor I mediates effects of exercise on the brain.

31 March 2020

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Circulating insulin-like growth factor I mediates exercise-induced increases in the number of new neurons in the adult hippocampus.

31 March 2020

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Neuronal activity drives localized blood-brain-barrier transport of serum insulin-like growth factor-I into the CNS.

31 March 2020

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Coordinated pattern of expression and localization of insulin-like growth factor-II (IGF-II) and IGF-binding protein-2 in the adult rat brain

31 March 2020

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Molecular evolution and functional characterization of Drosophila insulin-like peptides

31 March 2020

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Binding and internalization of insulin and insulin-like growth factors by isolated brain microvessels

31 March 2020

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The cerebrospinal fluid provides a proliferative niche for neural progenitor cells

31 March 2020

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Oral administration of a GSK3 inhibitor increases brain insulin-like growth factor I levels

31 March 2020

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Choroid Plexus Megalin Is Involved in Neuroprotection by Serum Insulin-Like Growth Factor I

31 March 2020

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Localization of insulin receptor mRNA in rat brain by in situ hybridization

31 March 2020

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Metabolic clearance of insulin from the cerebrospinal fluid in the anesthetized rat.

31 March 2020

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Transport of insulin-related peptides and glucose across the blood-brain barrier

31 March 2020

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Receptor-mediated endocytosis and degradation of insulin-like growth factor I and II in neonatal rat astrocytes

31 March 2020

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Glial and neuronal control of brain blood flow

31 March 2020

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Central actions of liver-derived insulin-like growth factor I underlying its pro-cognitive effects

31 March 2020

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Insulin-like growth factor I is required for vessel remodeling in the adult brain

31 March 2020

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Insulin and insulin-like growth factor I signalling in neurons

31 March 2020

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Brain IGF-1 receptors control mammalian growth and lifespan through a neuroendocrine mechanism

31 March 2020

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Genetic Analysis of Type-1 Insulin-like Growth Factor Receptor Signaling through Insulin Receptor Substrate-1 and -2 in Pancreatic β Cells

31 March 2020

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Functional inactivation of the IGF-I and insulin receptors in skeletal muscle causes type 2 diabetes

31 March 2020

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Knockout mice challenge our concepts of glucose homeostasis and the pathogenesis of diabetes

31 March 2020

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Acute and gradual increases in BDNF concentration elicit distinct signaling and functions in neurons

31 March 2020

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Irs-2 coordinates Igf-1 receptor-mediated beta-cell development and peripheral insulin signalling.

31 March 2020

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The role of the insulin-like growth factors in the central nervous system

31 March 2020

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Insulin-like growth factor (IGF)-I gene deletion

31 March 2020

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Insulin-like growth factor-I accelerates the cell cycle by decreasing G1 phase length and increases cell cycle reentry in the embryonic cerebral cortex.

31 March 2020

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Insulin-like growth factor 1 (IGF-1) mediates the effects of enriched environment (EE) on visual cortical development.

31 March 2020

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Insulin receptor signaling regulates synapse number, dendritic plasticity, and circuit function in vivo

31 March 2020

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Nutritional regulation of IGF-I expression during brain development in mice

31 March 2020

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IGF-I treatment reduces hyperphagia, obesity, and hypertension in metabolic disorders induced by fetal programming

31 March 2020

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Development of receptors for insulin and insulin-like growth factor-I in head and brain of chick embryos: autoradiographic localization.

31 March 2020

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Differential expression of the two nonallelic proinsulin genes in the developing mouse embryo

31 March 2020

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Cellular pattern of type-I insulin-like growth factor receptor gene expression during maturation of the rat brain: comparison with insulin-like growth factors I and II.

31 March 2020

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Fibroblast growth factor-mediated proliferation of central nervous system precursors depends on endogenous production of insulin-like growth factor I

31 March 2020

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Insulin-like growth factor 1 regulates developing brain glucose metabolism

31 March 2020

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Increased expression of insulin-like growth factor-I (IGF-I) during embryonic development produces neocortical overgrowth with differentially greater effects on specific cytoarchitectonic areas and cortical layers

31 March 2020

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Neural and head induction by insulin-like growth factor signals

31 March 2020

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Zebrafish IGF genes: gene duplication, conservation and divergence, and novel roles in midline and notochord development

31 March 2020

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Targeted gene knockdown in zebrafish reveals distinct intraembryonic functions for insulin-like growth factor II signaling.

31 March 2020

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Axons guided by insulin receptor in Drosophila visual system

31 March 2020

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Fat cells reactivate quiescent neuroblasts via TOR and glial insulin relays in Drosophila.

31 March 2020

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Insulin promotes dendritic spine and synapse formation by the PI3K/Akt/mTOR and Rac1 signaling pathways

31 March 2020

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Role of brain insulin receptor in control of body weight and reproduction

31 March 2020

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Critical periods for experience-dependent synaptic scaling in visual cortex

31 March 2020

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Selective induction of neocortical GABAergic neurons by the PDK1-Akt pathway through activation of Mash1.

31 March 2020

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IGF-I promotes neuronal migration and positioning in the olfactory bulb and the exit of neuroblasts from the subventricular zone

31 March 2020

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Insulin-like growth factor-I promotes neurogenesis and synaptogenesis in the hippocampal dentate gyrus during postnatal development

31 March 2020

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IGF-1 receptor is essential for the establishment of hippocampal neuronal polarity

31 March 2020

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IGF-I specifically enhances axon outgrowth of corticospinal motor neurons

31 March 2020

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RNA microarray analysis in prenatal mouse cochlea reveals novel IGF-I target genes: implication of MEF2 and FOXM1 transcription factors.

31 March 2020

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Type 1 insulin-like growth factor receptor signaling is essential for the development of the hippocampal formation and dentate gyrus

31 March 2020

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Astrocyte-specific overexpression of insulin-like growth factor-I promotes brain overgrowth and glial fibrillary acidic protein expression

31 March 2020

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Insulin-like growth factor-2 regulates early neural and cardiovascular system development in zebrafish embryos

31 March 2020

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Insulin-like growth factor II promotes in vitro cholinergic development of mouse septal neurons: comparison with the effects of insulin-like growth factor I.

31 March 2020

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Fetal hypothalamic neuroprogenitor cell culture: preferential differentiation paths induced by leptin and insulin

31 March 2020

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The insulin-like growth factor I system in the rat cerebellum: developmental regulation and role in neuronal survival and differentiation.

31 March 2020

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Cell death and control of cell survival in the oligodendrocyte lineage

31 March 2020

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Inhibition of Src-like kinases reveals Akt-dependent and -independent pathways in insulin-like growth factor I-mediated oligodendrocyte progenitor survival

31 March 2020

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Central nervous system control of food intake and body weight

31 March 2020

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Regulation of aversion to noxious food by Drosophila neuropeptide Y- and insulin-like systems

31 March 2020

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Western Style Diet Impairs Entrance of Blood-Borne Insulin-like Growth Factor-1 into the Brain

31 March 2020

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Direct control of germline stem cell division and cyst growth by neural insulin in Drosophila.

31 March 2020

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Amino acid-dependent activation of liver estrogen receptor alpha integrates metabolic and reproductive functions via IGF-1.

31 March 2020

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The insulin paradox: aging, proteotoxicity and neurodegeneration

31 March 2020

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The insulin-like growth factor system and its pleiotropic functions in brain

31 March 2020

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Co-ordinated and cellular specific induction of the components of the IGF/IGFBP axis in the rat brain following hypoxic-ischemic injury

31 March 2020

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IGF-I and the aging mammalian brain.

31 March 2020

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Presynaptic facilitation by neuropeptide signaling mediates odor-driven food search

31 March 2020

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Role of IGF signaling in olfactory sensory map formation and axon guidance

31 March 2020

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Intranasal insulin therapy for Alzheimer disease and amnestic mild cognitive impairment: a pilot clinical trial

31 March 2020

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Subcutaneous insulin-like growth factor-1 treatment in spinocerebellar ataxias: an open label clinical trial

31 March 2020

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Regulation of the phosphatase calcineurin by insulin-like growth factor I unveils a key role of astrocytes in Alzheimer's pathology.

31 March 2020

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Serum insulin-like growth factor I and ischemic brain injury.

31 March 2020

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Therapeutic actions of insulin-like growth factor I on APP/PS2 mice with severe brain amyloidosis.

31 March 2020

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Insulin-like growth factor-1 and post-ischemic brain injury

31 March 2020

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Brain repair and neuroprotection by serum insulin-like growth factor I.

31 March 2020

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Regulation of neuronal survival by the serine-threonine protein kinase Akt

31 March 2020

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Serum insulin-like growth factor I regulates brain amyloid-beta levels

31 March 2020

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Calcineurin in reactive astrocytes plays a key role in the interplay between proinflammatory and anti-inflammatory signals

31 March 2020

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Transynaptic modulation by insulin-like growth factor I of dendritic spines in Purkinje cells.

31 March 2020

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Functional characterization of des-IGF-1 action at excitatory synapses in the CA1 region of rat hippocampus.

31 March 2020

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Insulin-like growth factor-I and neurogenesis in the adult mammalian brain

31 March 2020

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Insulin-like signaling pathway functions in integrative response to an olfactory and a gustatory stimuli in Caenorhabditis elegans

31 March 2020

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Awake intranasal insulin delivery modifies protein complexes and alters memory, anxiety, and olfactory behaviors

31 March 2020

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Learning of the conditioned eye-blink response is impaired by an antisense insulin-like growth factor I oligonucleotide

31 March 2020

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Intracerebroventricular insulin improves spatial learning and memory in male Wistar rats

31 March 2020

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Intranasal insulin improves cognition and modulates beta-amyloid in early AD

31 March 2020

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Brain insulin receptors and spatial memory. Correlated changes in gene expression, tyrosine phosphorylation, and signaling molecules in the hippocampus of water maze trained rats

31 March 2020

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Cognitive changes during growth hormone replacement in adult men.

31 March 2020

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Insulin promotes rapid delivery of N-methyl-D- aspartate receptors to the cell surface by exocytosis

31 March 2020

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Recruitment of functional GABAA receptors to postsynaptic domains by insulin

31 March 2020

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Expression of cerebellar long-term depression requires postsynaptic clathrin-mediated endocytosis.

31 March 2020

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Potentiation of Quantal Secretion by Insulin‐Like Growth Factor‐1 at Developing Motoneurons in Xenopus Cell Culture

31 March 2020

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Effects of insulin-like growth factor 1 on synaptic excitability in cultured rat hippocampal neurons

31 March 2020

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Tyrosine phosphorylation of GluR2 is required for insulin-stimulated AMPA receptor endocytosis and LTD

31 March 2020

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Growth factor-dependent trafficking of cerebellar NMDA receptors via protein kinase B/Akt phosphorylation of NR2C.

31 March 2020

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Induction of Gene Expression of the Catecholamine‐Synthesizing Enzymes by Insulin‐Like Growth Factor‐I

31 March 2020

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IGF-1 Modulates N and L Calcium Channels in a PI 3-Kinase-Dependent Manner

31 March 2020

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Insulin-like growth factor-1 inhibits adult supraoptic neurons via complementary modulation of mechanoreceptors and glycine receptors.

31 March 2020

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Transcriptional up-regulation of cell surface Na V 1.7 sodium channels by insulin-like growth factor-1 via inhibition of glycogen synthase kinase-3β in adrenal chromaffin cells: enhancement of 22Na+ influx, 45Ca2+ influx and catecholamine secretion.

31 March 2020

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Diabetes and Insulin in Regulation of Brain Cholesterol Metabolism

31 March 2020

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The self-tuning neuron: synaptic scaling of excitatory synapses

31 March 2020

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Backpropagating action potentials trigger dendritic release of BDNF during spontaneous network activity

31 March 2020

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Activity-dependent IGF-1 exocytosis is controlled by the Ca(2+)-sensor synaptotagmin-10

31 March 2020

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The insulin receptor tyrosine kinase substrate p58/53 and the insulin receptor are components of CNS synapses

31 March 2020

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New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory?

31 March 2020

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Aspects of growth hormone and insulin-like growth factor-I related to neuroprotection, regeneration, and functional plasticity in the adult brain.

31 March 2020

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Epigenetic choreographers of neurogenesis in the adult mammalian brain

31 March 2020

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Inhibition of PI3K-Akt signaling blocks exercise-mediated enhancement of adult neurogenesis and synaptic plasticity in the dentate gyrus

31 March 2020

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The effects of exercise on spatial learning and anxiety-like behavior are mediated by an IGF-I-dependent mechanism related to hippocampal neurogenesis.

31 March 2020

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Depression: a case of neuronal life and death?

31 March 2020

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Exercise, learned helplessness, and the stress-resistant brain

31 March 2020

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Peripheral insulin-like growth factor-I produces antidepressant-like behavior and contributes to the effect of exercise

31 March 2020

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Frequency-modulated 50 kHz ultrasonic vocalizations: a tool for uncovering the molecular substrates of positive affect

31 March 2020

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Circulating IGF1 regulates hippocampal IGF1 levels and brain gene expression during adolescence

31 March 2020

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Uptake of circulating insulin-like growth factor-I into the cerebrospinal fluid of normal and diabetic rats and normalization of IGF-II mRNA content in diabetic rat brain

31 March 2020

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A kinase-independent role for unoccupied insulin and IGF-1 receptors in the control of apoptosis.

31 March 2020

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Does reduced IGF-1R signaling in Igf1r+/- mice alter aging?

31 March 2020

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Biochemical characterization of a new maize (Zea mays L.) peptide growth factor

31 March 2020

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New insulin-like growth factor (IGF)-precursor sequences from mammalian genomes: the molecular evolution of IGFs and associated peptides in primates

31 March 2020

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A Drosophila insulin-like peptide promotes growth during nonfeeding states

31 March 2020

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Imp-L2, a putative homolog of vertebrate IGF-binding protein 7, counteracts insulin signaling in Drosophila and is essential for starvation resistance.

31 March 2020

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Identification of a family of low-affinity insulin-like growth factor binding proteins (IGFBPs): Characterization of connective tissue growth factor as a member of the IGFBP superfamily

31 March 2020

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Insulin-like growth factor 1 (IGF-1) receptors in the human brain: quantitative autoradiographic localization

31 March 2020

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Insulin-like growth factor-I receptors in human brain and pituitary gland: an autoradiographic study

31 March 2020

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Insulin/insulin-like growth factor I hybrid receptors have different biological characteristics depending on the insulin receptor isoform involved

31 March 2020

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Insulin binding sites localized to nerve terminals in rat median eminence and arcuate nucleus.

31 March 2020

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Insulin-like growth factor signaling regulates the timing of sensory cell differentiation in the mouse cochlea.

31 March 2020

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Central insulin and leptin-mediated autonomic control of glucose homeostasis.

31 March 2020

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12 December 2020

Toward a comprehensive neurobiology of IGF-I.

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12 December 2020

Expression of IGF-I and -II mRNA in the brain and craniofacial region of the rat fetus

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12 December 2020

Spatial and temporal changes in the insulin-like growth factor (IGF) axis indicate autocrine/paracrine actions of IGF-I within wounds of the rat brain

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12 December 2020

The insulin-like growth factor-binding protein (IGFBP) superfamily

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12 December 2020

Insulin gene expression and insulin synthesis in mammalian neuronal cells

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12 December 2020

Chemical transmission in the sea anemone Nematostella vectensis: A genomic perspective

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12 December 2020

Insulin-Like Growth Factor II Expression in the Developing Human Brain

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12 December 2020

Role of insulin-like growth factors in embryonic and postnatal growth

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12 December 2020

Megalin is an endocytic receptor for insulin

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12 December 2020

Synergistic interaction between insulin-like growth factors-I and -II in central regulation of pulsatile growth hormone secretion

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12 December 2020

Differential temporal and spatial expression of insulin-like growth factor binding protein-2 in developing chick ocular tissues.

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12 December 2020

Insulin-like receptor and insulin-like peptide are localized at neuromuscular junctions in Drosophila

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12 December 2020

Insulin is released from rat brain neuronal cells in culture

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12 December 2020

Kinetics and specificity of insulin uptake from plasma into cerebrospinal fluid

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12 December 2020

Restoration of insulin-like growth factor binding protein-related protein 1 has a tumor-suppressive activity through induction of apoptosis in human prostate cancer.

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12 December 2020

Distinct sites of insulin-like growth factor (IGF)-II expression and localization in lesioned rat brain: possible roles of IGF binding proteins (IGFBPs) in the mediation of IGF-II activity

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12 December 2020