Pancreatic cancer stem cell biology and its therapeutic implications (Q37952082)

25 August 2017

title

Pancreatic cancer stem cell biology and its therapeutic implications (English)

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25 August 2017

main subject

neoplastic stem cells

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Filip Bednar

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25 August 2017

Diane M Simeone

series ordinal

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25 August 2017

publication date

3 November 2011

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Journal of Gastroenterology

25 August 2017

published in

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25 August 2017

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25 August 2017

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25 August 2017

page(s)

1345-1352

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Stem cells, cancer, and cancer stem cells

25 August 2017

cites work

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Prospective identification of tumorigenic breast cancer cells

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Identification of human brain tumour initiating cells

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Phenotypic characterization of human colorectal cancer stem cells

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A human colon cancer cell capable of initiating tumour growth in immunodeficient mice

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Identification and expansion of human colon-cancer-initiating cells

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Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma

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Identification of pancreatic cancer stem cells

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Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer

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Eyes wide open: a critical review of sphere-formation as an assay for stem cells

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A genetic model for colorectal tumorigenesis

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Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

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Distant metastasis occurs late during the genetic evolution of pancreatic cancer

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Isolation and molecular characterization of cancer stem cells in MMTV-Wnt-1 murine breast tumors

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Identification of tumor-initiating cells in a p53-null mouse model of breast cancer

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Primary tumor genotype is an important determinant in identification of lung cancer propagating cells

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Wnt activity defines colon cancer stem cells and is regulated by the microenvironment

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Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state

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Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion

21 January 2018

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Stochastic state transitions give rise to phenotypic equilibrium in populations of cancer cells

21 January 2018

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The JAK2/STAT3 signaling pathway is required for growth of CD44+CD24– stem cell–like breast cancer cells in human tumors

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Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis

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A paracrine requirement for hedgehog signalling in cancer

21 January 2018

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Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer

21 January 2018

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Combined targeted treatment to eliminate tumorigenic cancer stem cells in human pancreatic cancer.

21 January 2018

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Epithelial-cadherin and beta-catenin expression changes in pancreatic intraepithelial neoplasia

21 January 2018

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Oncogenic function of ATDC in pancreatic cancer through Wnt pathway activation and beta-catenin stabilization

21 January 2018

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Cutaneous cancer stem cell maintenance is dependent on beta-catenin signalling

21 January 2018

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Wnt signalling in stem cells and cancer

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21 January 2018

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21 January 2018

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The epithelial-mesenchymal transition generates cells with properties of stem cells

21 January 2018

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Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy

21 January 2018

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The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs

21 January 2018

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Epithelial to mesenchymal transition contributes to drug resistance in pancreatic cancer

21 January 2018

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Development and characterization of gemcitabine-resistant pancreatic tumor cells.

21 January 2018

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The role of PTEN/Akt/PI3K signaling in the maintenance and viability of prostate cancer stem-like cell populations

21 January 2018

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mTOR activation induces tumor suppressors that inhibit leukemogenesis and deplete hematopoietic stem cells after Pten deletion.

21 January 2018

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Activation of the PTEN/mTOR/STAT3 pathway in breast cancer stem-like cells is required for viability and maintenance

21 January 2018

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PI3K pathway regulates survival of cancer stem cells residing in the perivascular niche following radiation in medulloblastoma in vivo

21 January 2018

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Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells

21 January 2018

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Stat3/Socs3 Activation by IL-6 Transsignaling Promotes Progression of Pancreatic Intraepithelial Neoplasia and Development of Pancreatic Cancer

21 January 2018

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12 December 2020

Colorectal cancer stem cells are enriched in xenogeneic tumors following chemotherapy

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12 December 2020

ALDH Activity Selectively Defines an Enhanced Tumor-Initiating Cell Population Relative to CD133 Expression in Human Pancreatic Adenocarcinoma

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12 December 2020

Common activation of canonical Wnt signaling in pancreatic adenocarcinoma.

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12 December 2020

Progression model for pancreatic cancer.

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12 December 2020

Identification of a cancer stem cell in human brain tumors

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12 December 2020

c-Met is a marker of pancreatic cancer stem cells and therapeutic target

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12 December 2020

The mammary progenitor marker CD61/beta3 integrin identifies cancer stem cells in mouse models of mammary tumorigenesis

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12 December 2020

10.1007/S00535-011-0494-7

Identifiers

DOI

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25 August 2017

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