TLR-dependent T cell activation in autoimmunity. (Q37957689)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22094985%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

title

TLR-dependent T cell activation in autoimmunity (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22094985%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

0 references

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22094985%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Kingston H G Mills

1 reference

25 August 2017

publication date

18 November 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22094985%20AND%20SRC:MED&resulttype=core&format=json

Nature Reviews Immunology

16 January 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22094985%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

volume

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22094985%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

issue

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22094985%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

page(s)

807-822

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22094985%20AND%20SRC:MED&resulttype=core&format=json

Innate immune recognition

16 January 2020

cites work

1 reference

Induction, function and regulation of IL-17-producing T cells

31 March 2020

1 reference

Regulatory T cells exert checks and balances on self tolerance and autoimmunity

31 March 2020

1 reference

Pathogen recognition and innate immunity

31 March 2020

1 reference

Targeting Toll-like receptors: emerging therapeutics?

31 March 2020

1 reference

Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity.

31 March 2020

1 reference

Stimulation of the intracellular bacterial sensor NOD2 programs dendritic cells to promote interleukin-17 production in human memory T cells

31 March 2020

1 reference

Caspase-1-processed cytokines IL-1beta and IL-18 promote IL-17 production by gammadelta and CD4 T cells that mediate autoimmunity.

31 March 2020

1 reference

Induction of intestinal Th17 cells by segmented filamentous bacteria

31 March 2020

1 reference

Innate immunity mediated by TLR9 modulates pathogenicity in an animal model of multiple sclerosis

31 March 2020

1 reference

Stimulation of TLR2 and TLR4 differentially skews the balance of T cells in a mouse model of arthritis

31 March 2020

1 reference

Inhibition of ERK MAPK Suppresses IL-23- and IL-1-Driven IL-17 Production and Attenuates Autoimmune Disease

31 March 2020

1 reference

Attenuating regulatory T cell induction by TLR agonists through inhibition of p38 MAPK signaling in dendritic cells enhances their efficacy as vaccine adjuvants and cancer immunotherapeutics.

31 March 2020

1 reference

TLR ligand suppression or enhancement of Treg cells? A double-edged sword in immunity to tumours

31 March 2020

1 reference

TLR, NLR Agonists, and Other Immune Modulators as Infectious Disease Vaccine Adjuvants

31 March 2020

1 reference

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

31 March 2020

1 reference

Transforming growth factor-beta induces development of the T(H)17 lineage

31 March 2020

1 reference

TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells

31 March 2020

1 reference

A crucial role for interleukin (IL)-1 in the induction of IL-17-producing T cells that mediate autoimmune encephalomyelitis.

31 March 2020

1 reference

Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17

31 March 2020

1 reference

Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages

31 March 2020

1 reference

A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17

31 March 2020

1 reference

Interleukin-17-producing gammadelta T cells selectively expand in response to pathogen products and environmental signals

31 March 2020

1 reference

Cutting edge: NKT cells constitutively express IL-23 receptor and RORgammat and rapidly produce IL-17 upon receptor ligation in an IL-6-independent fashion

31 March 2020

1 reference

Lymphoid tissue inducer-like cells are an innate source of IL-17 and IL-22

31 March 2020

1 reference

Infiltration of Th1 and Th17 cells and activation of microglia in the CNS during the course of experimental autoimmune encephalomyelitis

31 March 2020

1 reference

Association of the polymorphism for Toll-like receptor 2 with type 1 diabetes susceptibility.

31 March 2020

1 reference

TLR2, TLR4 and TLR9 polymorphisms and Crohn's disease in a New Zealand Caucasian cohort

31 March 2020

1 reference

Synergy between TLR9 and NOD2 innate immune responses is lost in genetic Crohn's disease

31 March 2020

1 reference

Induction, exacerbation and inhibition of allergic and autoimmune diseases by infection

31 March 2020

1 reference

Dysregulated Epstein-Barr virus infection in the multiple sclerosis brain

31 March 2020

1 reference

Prospective study on the relationship between infections and multiple sclerosis exacerbations

31 March 2020

1 reference

The risk of relapses in multiple sclerosis during systemic infections

31 March 2020

1 reference

Persistence of B19 parvovirus in synovial membranes of patients with rheumatoid arthritis

31 March 2020

1 reference

Synovial Epstein-Barr virus infection increases the risk of rheumatoid arthritis in individuals with the shared HLA-DR4 epitope

31 March 2020

1 reference

Interactions between the host innate immune system and microbes in inflammatory bowel disease

31 March 2020

1 reference

Gut-residing segmented filamentous bacteria drive autoimmune arthritis via T helper 17 cells

31 March 2020

1 reference

ATP drives lamina propria T(H)17 cell differentiation

31 March 2020

1 reference

Microbiota innate stimulation is a prerequisite for T cell spontaneous proliferation and induction of experimental colitis

31 March 2020

1 reference

Streptococcus pneumoniae Infection aggravates experimental autoimmune encephalomyelitis via Toll-like receptor 2.

31 March 2020

1 reference

Antigen-presenting cells containing bacterial peptidoglycan in synovial tissues of rheumatoid arthritis patients coexpress costimulatory molecules and cytokines

31 March 2020

1 reference

The presence of peptidoglycan-polysaccharide complexes in the bowel wall and the cellular responses to these complexes in Crohn's disease

31 March 2020

1 reference

Phagocytes containing a disease-promoting Toll-like receptor/Nod ligand are present in the brain during demyelinating disease in primates

31 March 2020

1 reference

Bacterial peptidoglycan and immune reactivity in the central nervous system in multiple sclerosis

31 March 2020

1 reference

Broad expression of Toll-like receptors in the human central nervous system

31 March 2020

1 reference

Generalized exacerbation of psoriasis associated with imiquimod cream treatment of superficial basal cell carcinomas

31 March 2020

1 reference

The effect of infections on susceptibility to autoimmune and allergic diseases

31 March 2020

1 reference

T-cell regulation in helminth parasite infections: implications for inflammatory diseases

31 March 2020

1 reference

Family size, infection and atopy: the first decade of the "hygiene hypothesis".

31 March 2020

1 reference

Infection with a Helminth Parasite Attenuates Autoimmunity through TGF- -Mediated Suppression of Th17 and Th1 Responses

31 March 2020

1 reference

Central nervous system demyelinating disease protection by the human commensal Bacteroides fragilis depends on polysaccharide A expression.

31 March 2020

1 reference

Hydrophobicity: an ancient damage-associated molecular pattern that initiates innate immune responses.

31 March 2020

1 reference

Alarmins: chemotactic activators of immune responses

31 March 2020

1 reference

DAMPs, PAMPs and alarmins: all we need to know about danger

31 March 2020

1 reference

HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses

31 March 2020

1 reference

Expression of high mobility group box chromosomal protein 1 and its modulating effects on downstream cytokines in systemic lupus erythematosus.

31 March 2020

1 reference

Identification of a key pathway required for the sterile inflammatory response triggered by dying cells

31 March 2020

1 reference

Toll-like receptor 2 and poly(ADP-ribose) polymerase 1 promote central nervous system neuroinflammation in progressive EAE.

31 March 2020

1 reference

The Toll-like receptor adaptor proteins MyD88 and Mal/TIRAP contribute to the inflammatory and destructive processes in a human model of rheumatoid arthritis

31 March 2020

1 reference

Nucleic acid-stimulated antigen-presenting cells trigger T cells to induce disease in a rat transfer model of inflammatory arthritis

31 March 2020

1 reference

Unexpected regulatory roles of TLR4 and TLR9 in experimental autoimmune encephalomyelitis

31 March 2020

1 reference

Toll-like receptor 2 signaling in CD4(+) T lymphocytes promotes T helper 17 responses and regulates the pathogenesis of autoimmune disease.

31 March 2020

1 reference

Activation of APCs through CD40 or Toll-like receptor 9 overcomes tolerance and precipitates autoimmune disease

31 March 2020

1 reference

Commensal DNA limits regulatory T cell conversion and is a natural adjuvant of intestinal immune responses

31 March 2020

1 reference

Cutting Edge: TLR3 stimulation suppresses experimental autoimmune encephalomyelitis by inducing endogenous IFN-beta

31 March 2020

1 reference

Induction of acute arthritis in mice by peptidoglycan derived from gram-positive bacteria and its possible role in cytokine production

31 March 2020

1 reference

TLR2 modulates inflammation in zymosan-induced arthritis in mice

31 March 2020

1 reference

Immunostimulatory DNA sequences influence the course of adjuvant arthritis

31 March 2020

1 reference

Inhibition of Toll-like receptor 4 breaks the inflammatory loop in autoimmune destructive arthritis.

31 March 2020

1 reference

Essential role of the MyD88 pathway, but nonessential roles of TLRs 2, 4, and 9, in the adjuvant effect promoting Th1-mediated autoimmunity

31 March 2020

1 reference

Toll-like receptor 2 senses beta-cell death and contributes to the initiation of autoimmune diabetes

31 March 2020

1 reference

Toll-like receptor 2 induces Th17 myeloperoxidase autoimmunity while Toll-like receptor 9 drives Th1 autoimmunity in murine vasculitis

31 March 2020

1 reference

Imiquimod-induced psoriasis-like skin inflammation in mice is mediated via the IL-23/IL-17 axis.

31 March 2020

1 reference

Optimal induction of T helper 17 cells in humans requires T cell receptor ligation in the context of Toll-like receptor-activated monocytes.

31 March 2020

1 reference

TLR4 mediates vaccine-induced protective cellular immunity to Bordetella pertussis: role of IL-17-producing T cells.

31 March 2020

1 reference

Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells

31 March 2020

1 reference

Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17

31 March 2020

1 reference

Specific microbiota direct the differentiation of IL-17-producing T-helper cells in the mucosa of the small intestine

31 March 2020

1 reference

Encephalitogenicity of complete Freund's adjuvant relative to CpG is linked to induction of Th17 cells

31 March 2020

1 reference

Activation of antigen-presenting cells by microbial products breaks self tolerance and induces autoimmune disease

31 March 2020

1 reference

Signals mediated by transforming growth factor-beta initiate autoimmune encephalomyelitis, but chronic inflammation is needed to sustain disease.

31 March 2020

1 reference

Multiple toll-like receptor agonists act as potent adjuvants in the induction of autoimmunity

31 March 2020

1 reference

Toll-like receptor 8-mediated reversal of CD4+ regulatory T cell function

31 March 2020

1 reference

Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells

31 March 2020

1 reference

Persistent Toll-like receptor signals are required for reversal of regulatory T cell-mediated CD8 tolerance

31 March 2020

1 reference

Regulatory T cell suppression and anergy are differentially regulated by proinflammatory cytokines produced by TLR-activated dendritic cells

31 March 2020

1 reference

Cutting edge: Lipopolysaccharide induces IL-10-producing regulatory CD4+ T cells that suppress the CD8+ T cell response

31 March 2020

1 reference

Cutting edge: TLR2 directly triggers Th1 effector functions

31 March 2020

1 reference

TLR ligands act directly upon T cells to restore proliferation in the absence of protein kinase C-theta signaling and promote autoimmune myocarditis

31 March 2020

1 reference

CD8+ T cells and neuronal damage: direct and collateral mechanisms of cytotoxicity and impaired electrical excitability

31 March 2020

1 reference

Activation profile of Toll-like receptors of peripheral blood lymphocytes in patients with systemic lupus erythematosus.

31 March 2020

1 reference

Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides

31 March 2020

1 reference

TLR2 engagement on CD8 T cells lowers the thresholdfor optimal antigen-induced T cell activation

31 March 2020

1 reference

gammadelta T cells: an important source of IL-17.

31 March 2020

1 reference

Regulatory T cells selectively express toll-like receptors and are activated by lipopolysaccharide

31 March 2020

1 reference

Human CD4+ T Cells Express TLR5 and Its Ligand Flagellin Enhances the Suppressive Capacity and Expression of FOXP3 in CD4+CD25+ T Regulatory Cells

31 March 2020

1 reference

Toll-like receptor 2 controls expansion and function of regulatory T cells

31 March 2020

1 reference

Toll-like receptor 2 signaling modulates the functions of CD4+ CD25+ regulatory T cells

31 March 2020

1 reference

The Toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota

31 March 2020

1 reference

A synthetic TLR4 antagonist has anti-inflammatory effects in two murine models of inflammatory bowel disease

31 March 2020

1 reference

A novel Toll-like receptor 4 antagonist antibody ameliorates inflammation but impairs mucosal healing in murine colitis

31 March 2020

1 reference

Inhibition of endotoxin response by e5564, a novel Toll-like receptor 4-directed endotoxin antagonist

31 March 2020

1 reference

Myocardial ischemia/reperfusion injury is mediated by leukocytic toll-like receptor-2 and reduced by systemic administration of a novel anti-toll-like receptor-2 antibody

31 March 2020

1 reference

Immunology. Danger, microbes, and homeostasis.

31 March 2020

1 reference

Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 76-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 1)

31 March 2020

1 reference

Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

31 March 2020

1 reference

Interferon-gamma confers resistance to experimental allergic encephalomyelitis.

31 March 2020

1 reference

IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis

31 March 2020

1 reference

IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

31 March 2020

1 reference

Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation

31 March 2020

1 reference

IL-12- and IL-23-modulated T cells induce distinct types of EAE based on histology, CNS chemokine profile, and response to cytokine inhibition.

31 March 2020

1 reference

Either a Th17 or a Th1 effector response can drive autoimmunity: conditions of disease induction affect dominant effector category

31 March 2020

1 reference

Exacerbations of multiple sclerosis in patients treated with gamma interferon

31 March 2020

1 reference

Regulation of interleukin-1beta by interferon-gamma is species specific, limited by suppressor of cytokine signalling 1 and influences interleukin-17 production

31 March 2020

1 reference

Phenotypic and functional features of human Th17 cells

31 March 2020

1 reference

The role of TLR2, TRL3, TRL4, and TRL9 signaling in the pathogenesis of autoimmune disease in a retinal autoimmunity model

31 March 2020

1 reference

Bacterial lipopolysaccharide acts as an adjuvant to induce autoimmune arthritis in mice

31 March 2020

1 reference

Accelerated collagen-induced arthritis in IFN-gamma receptor-deficient mice

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22094985

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mouse and pig models for studies of natural and vaccine-induced immunity to Bordetella pertussis.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22094985