Mitochondria and fungal pathogenesis: drug tolerance, virulence, and potential for antifungal therapy. (Q37934279)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21926328%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

review article

1 reference

title

Mitochondria and fungal pathogenesis: drug tolerance, virulence, and potential for antifungal therapy (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21926328%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

0 references

1 reference

1 reference

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12 February 2020

author name string

Miguel Shingu-Vazquez

series ordinal

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12 February 2020

publication date

16 September 2011

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12 February 2020

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12 February 2020

volume

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12 February 2020

issue

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12 February 2020

page(s)

1376-1383

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Cryptococcus neoformans requires a functional glycolytic pathway for disease but not persistence in the host

12 February 2020

cites work

1 reference

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Pathway analysis of Candida albicans survival and virulence determinants in a murine infection model

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Cytochrome P450 enzymes in the fungal kingdom

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Systematic screens of a Candida albicans homozygous deletion library decouple morphogenetic switching and pathogenicity

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6 September 2017

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The fatal fungal outbreak on Vancouver Island is characterized by enhanced intracellular parasitism driven by mitochondrial regulation

6 September 2017

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An ER-mitochondria tethering complex revealed by a synthetic biology screen

6 September 2017

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Ups1p and Ups2p antagonistically regulate cardiolipin metabolism in mitochondria

6 September 2017

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Hypersusceptibility to azole antifungals in a clinical isolate of Candida glabrata with reduced aerobic growth

6 September 2017

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Translocation and assembly of mitochondrially coded Saccharomyces cerevisiae cytochrome c oxidase subunit Cox2 by Oxa1 and Yme1 in the absence of Cox18.

6 September 2017

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The genetic interactome of prohibitins: coordinated control of cardiolipin and phosphatidylethanolamine by conserved regulators in mitochondria

6 September 2017

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Coordinate control of lipid composition and drug transport activities is required for normal multidrug resistance in fungi.

6 September 2017

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Gain of function mutations in CgPDR1 of Candida glabrata not only mediate antifungal resistance but also enhance virulence

6 September 2017

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Supercomplex organization of the oxidative phosphorylation enzymes in yeast mitochondria

6 September 2017

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Functional analysis of Candida albicans GPI-anchored proteins: roles in cell wall integrity and caspofungin sensitivity

6 September 2017

1 reference

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Cellular functions of cardiolipin in yeast

6 September 2017

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The chemical genomic portrait of yeast: uncovering a phenotype for all genes

6 September 2017

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Transcriptional rewiring of fungal galactose-metabolism circuitry

6 September 2017

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Oxa1 directly interacts with Atp9 and mediates its assembly into the mitochondrial F1Fo-ATP synthase complex

6 September 2017

1 reference

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A Candida albicans petite mutant strain with uncoupled oxidative phosphorylation overexpresses MDR1 and has diminished susceptibility to fluconazole and voriconazole

6 September 2017

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Candida albicans transcription factor Ace2 regulates metabolism and is required for filamentation in hypoxic conditions

6 September 2017

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6 September 2017

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Candida glabrata PDR1, a transcriptional regulator of a pleiotropic drug resistance network, mediates azole resistance in clinical isolates and petite mutants

6 September 2017

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6 September 2017

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6 September 2017

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Synthetic lethal interaction of the mitochondrial phosphatidylethanolamine and cardiolipin biosynthetic pathways in Saccharomyces cerevisiae

6 September 2017

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6 September 2017

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6 September 2017

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Characterization of Cryptococcus neoformans variety gattii SOD2 reveals distinct roles of the two superoxide dismutases in fungal biology and virulence

6 September 2017

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Loss of function of KRE5 suppresses temperature sensitivity of mutants lacking mitochondrial anionic lipids

6 September 2017

1 reference

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Differential regulation of ceramide synthase components LAC1 and LAG1 in Saccharomyces cerevisiae.

6 September 2017

1 reference

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Functional genomic analysis of fluconazole susceptibility in the pathogenic yeast Candida glabrata: roles of calcium signaling and mitochondria.

6 September 2017

1 reference

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Cryptococcus neoformans gene expression during experimental cryptococcal meningitis

6 September 2017

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Biogenesis and cellular dynamics of aminoglycerophospholipids

6 September 2017

1 reference

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Pkh1 and Pkh2 differentially phosphorylate and activate Ypk1 and Ykr2 and define protein kinase modules required for maintenance of cell wall integrity

6 September 2017

1 reference

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Yeast protein kinases and the RHO1 exchange factor TUS1 are novel components of the cell integrity pathway in yeast

6 September 2017

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Sphingoid base signaling via Pkh kinases is required for endocytosis in yeast

6 September 2017

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Saccharomyces cerevisiae multidrug resistance gene expression inversely correlates with the status of the F(0) component of the mitochondrial ATPase

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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PDK1 homologs activate the Pkc1-mitogen-activated protein kinase pathway in yeast

6 September 2017

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6 September 2017

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Functional counterparts of mammalian protein kinases PDK1 and SGK in budding yeast

6 September 2017

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Identification of the FKS1 gene of Candida albicans as the essential target of 1,3-beta-D-glucan synthase inhibitors

6 September 2017

1 reference

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Yeast RPO41 gene product is required for transcription and maintenance of the mitochondrial genome

6 September 2017

1 reference

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Involvement of Candida albicans pyruvate dehydrogenase complex protein X (Pdx1) in filamentation

6 September 2017

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Mechanisms of azole resistance in petite mutants of Candida glabrata

14 September 2017

1 reference

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Involvement of an Alternative Oxidase in Oxidative Stress and Mycelium-to-Yeast Differentiation in Paracoccidioides brasiliensis

28 September 2017

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Regulation of the CgPdr1 Transcription Factor from the Pathogen Candida glabrata

23 June 2018

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Phosphatidylethanolamine synthesized by four different pathways is supplied to the plasma membrane of the yeast Saccharomyces cerevisiae

23 June 2018

1 reference

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Evidence for the bifunctional nature of mitochondrial phosphatidylserine decarboxylase: role in Pdr3-dependent retrograde regulation of PDR5 expression

23 June 2018

1 reference

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Inhibition of Candida parapsilosis mitochondrial respiratory pathways enhances susceptibility to caspofungin

23 June 2018

1 reference

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Involvement of Candida albicans NADH dehydrogenase complex I in filamentation

23 June 2018

1 reference

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Roles of dihydrolipoamide dehydrogenase Lpd1 in Candida albicans filamentation

23 June 2018

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Phosphatidylserine synthase and phosphatidylserine decarboxylase are essential for cell wall integrity and virulence in Candida albicans

1 September 2018

1 reference

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Functional characterization of the CgPGS1 gene reveals a link between mitochondrial phospholipid homeostasis and drug resistance in Candida glabrata

1 September 2018

1 reference

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Tetracycline alters drug susceptibility in Candida albicans and other pathogenic fungi

1 September 2018

1 reference

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The phosphatidylethanolamine level of yeast mitochondria is affected by the mitochondrial components Oxa1p and Yme1p

1 September 2018

1 reference

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Up-regulation of the cell integrity pathway in saccharomyces cerevisiae suppresses temperature sensitivity of the pgs1Delta mutant.

1 September 2018

1 reference

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Inhibition of specific electron transport pathways leads to oxidative stress and decreased Candida albicans proliferation.

1 September 2018

1 reference

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The concomitant expression and availability of conventional and alternative, cyanide-insensitive, respiratory pathways in Candida albicans

1 September 2018

1 reference

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Biological consequences of petite mutations in Candida glabrata

1 September 2018

1 reference

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The sphingoid long chain base phytosphingosine activates AGC-type protein kinases in Saccharomyces cerevisiae including Ypk1, Ypk2, and Sch9.

1 September 2018

1 reference

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Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae

1 September 2018

1 reference

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Cardiolipin biosynthesis and mitochondrial respiratory chain function are interdependent

1 September 2018

1 reference

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Disruption of mitochondrial function in Candida albicans leads to reduced cellular ergosterol levels and elevated growth in the presence of amphotericin B.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3209048

Erythromycin, an inhibitor of mitoribosomal protein biosynthesis, alters the amphotericin B susceptibility of Candida albicans

1 September 2018

1 reference

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Respiratory chain network in mitochondria of Candida parapsilosis: ADP/O appraisal of the multiple electron pathways

1 September 2018

1 reference

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Interorganellar communication. Altered nuclear gene expression profiles in a yeast mitochondrial dna mutant.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3209048

OXA1, a Saccharomyces cerevisiae nuclear gene whose sequence is conserved from prokaryotes to eukaryotes controls cytochrome oxidase biogenesis

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3209048

Coordinate Control of Sphingolipid Biosynthesis and Multidrug Resistance inSaccharomyces cerevisiae

1 September 2018

1 reference

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In-vivo selection of an azole-resistant petite mutant of Candida glabrata

3 December 2018

1 reference

12 December 2020

Phosphatidylethanolamine is the donor of the phosphorylethanolamine linked to the alpha1,4-linked mannose of yeast GPI structures

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12 December 2020

Protein export across the inner membrane of mitochondria: the nature of translocated domains determines the dependence on the Oxa1 translocase

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12 December 2020

Cryptococcus neoformans mitochondrial genomes from serotype A and D strains do not influence virulence

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12 December 2020

Uncoupling of oxidative phosphorylation enables Candida albicans to resist killing by phagocytes and persist in tissue

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12 December 2020

Impact of mitochondrial function on yeast susceptibility to antifungal compounds

1 reference

12 December 2020

Silencing of mitochondrial alternative oxidase gene of Aspergillus fumigatus enhances reactive oxygen species production and killing of the fungus by macrophages

1 reference

12 December 2020

Identifiers

DOI

10.1128/EC.05184-11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21926328%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21926328%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

PubMed publication ID

21926328

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21926328%20AND%20SRC:MED&resulttype=core&format=json