Epithelial organization, cell polarity and tumorigenesis (Q37904131)

25 August 2017

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title

Epithelial organization, cell polarity and tumorigenesis (English)

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25 August 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21782440

7 December 2024

author name string

Luke Martin McCaffrey

series ordinal

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25 August 2017

Ian G. Macara

series ordinal

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21782440

7 December 2024

language of work or name

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21 July 2011

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full work available at URL

25 August 2017

https://api.elsevier.com/content/article/PII:S0962892411001267?httpAccept=text/xml

1 reference

Crossref

DOI

https://api.crossref.org/works/10.1016/J.TCB.2011.06.005

https://api.elsevier.com/content/article/PII:S0962892411001267?httpAccept=text/plain

7 December 2024

1 reference

Crossref

DOI

https://api.crossref.org/works/10.1016/J.TCB.2011.06.005

7 December 2024

published in

Trends in Cell Biology

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25 August 2017

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25 August 2017

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25 August 2017

page(s)

727-735

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A polarized epithelium organized by beta- and alpha-catenin predates cadherin and metazoan origins

25 August 2017

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7 December 2024

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E1a induces the expression of epithelial characteristics

7 December 2024

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p63 in epithelial survival, germ cell surveillance, and neoplasia

7 December 2024

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Gata-3 is an essential regulator of mammary-gland morphogenesis and luminal-cell differentiation

7 December 2024

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GATA-3 maintains the differentiation of the luminal cell fate in the mammary gland

7 December 2024

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The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1

7 December 2024

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The ZEB/miR-200 feedback loop--a motor of cellular plasticity in development and cancer?

7 December 2024

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The transcriptional repressor ZEB1 promotes metastasis and loss of cell polarity in cancer

7 December 2024

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p53 regulates epithelial-mesenchymal transition and stem cell properties through modulating miRNAs.

7 December 2024

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Genetic predisposition directs breast cancer phenotype by dictating progenitor cell fate

7 December 2024

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The PAR proteins: fundamental players in animal cell polarization

7 December 2024

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LGN regulates mitotic spindle orientation during epithelial morphogenesis

7 December 2024

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Cdc42 controls spindle orientation to position the apical surface during epithelial morphogenesis

7 December 2024

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Par3 controls epithelial spindle orientation by aPKC-mediated phosphorylation of apical Pins

7 December 2024

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Tuba, a Cdc42 GEF, is required for polarized spindle orientation during epithelial cyst formation

7 December 2024

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The Cdc42 GEF Intersectin 2 controls mitotic spindle orientation to form the lumen during epithelial morphogenesis.

7 December 2024

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Mammalian Pins is a conformational switch that links NuMA to heterotrimeric G proteins

7 December 2024

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The ZO-1-associated Y-box factor ZONAB regulates epithelial cell proliferation and cell density

7 December 2024

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7 December 2024

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7 December 2024

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7 December 2024

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7 December 2024

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7 December 2024

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7 December 2024

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7 December 2024

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7 December 2024

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The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-β-SMAD pathway.

7 December 2024

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KIBRA suppresses apical exocytosis through inhibition of aPKC kinase activity in epithelial cells.

7 December 2024

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KIBRA is a novel substrate for protein kinase Czeta

7 December 2024

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An aPKC-exocyst complex controls paxillin phosphorylation and migration through localised JNK1 activation

7 December 2024

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7 December 2024

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Collective cell migration requires suppression of actomyosin at cell-cell contacts mediated by DDR1 and the cell polarity regulators Par3 and Par6.

7 December 2024

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ASPP2 regulates epithelial cell polarity through the PAR complex.

7 December 2024

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ASPP2 binds Par-3 and controls the polarity and proliferation of neural progenitors during CNS development

7 December 2024

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PP1 Cooperates with ASPP2 to Dephosphorylate and Activate TAZ

7 December 2024

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Cytoplasmic ASPP1 inhibits apoptosis through the control of YAP.

7 December 2024

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Epithelial polarity and proliferation control: links from the Drosophila neoplastic tumor suppressors

7 December 2024

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Myc, cell competition, and compensatory proliferation

7 December 2024

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Elimination of oncogenic neighbors by JNK-mediated engulfment in Drosophila.

7 December 2024

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Context-dependent compensatory proliferation in epithelial homeostasis and tumorigenesis

7 December 2024

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A Genetic Screen in Drosophila for Metastatic Behavior

7 December 2024

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Interaction between Ras(V12) and scribbled clones induces tumour growth and invasion

7 December 2024

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Interactions between normal and transformed epithelial cells: Their contributions to tumourigenesis

7 December 2024

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Involvement of Lgl and Mahjong/VprBP in cell competition

7 December 2024

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The Par3/aPKC interaction is essential for end bud remodeling and progenitor differentiation during mammary gland morphogenesis

7 December 2024

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https://api.crossref.org/works/10.1016/J.TCB.2011.06.005

Par6-aPKC uncouples ErbB2 induced disruption of polarized epithelial organization from proliferation control

7 December 2024

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https://api.crossref.org/works/10.1016/J.TCB.2011.06.005

Atypical PKCiota contributes to poor prognosis through loss of apical-basal polarity and cyclin E overexpression in ovarian cancer.

7 December 2024

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https://api.crossref.org/works/10.1016/J.TCB.2011.06.005

The polarity protein Par6 induces cell proliferation and is overexpressed in breast cancer

7 December 2024

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https://api.crossref.org/works/10.1016/J.TCB.2011.06.005

Deregulation of scribble promotes mammary tumorigenesis and reveals a role for cell polarity in carcinoma

7 December 2024

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https://api.crossref.org/works/10.1016/J.TCB.2011.06.005

Control of tumourigenesis by the Scribble/Dlg/Lgl polarity module

7 December 2024

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https://api.crossref.org/works/10.1016/J.TCB.2011.06.005

The overexpression and altered localization of the atypical protein kinase C λ/ι in breast cancer correlates with the pathologic type of these tumors

7 December 2024

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https://api.crossref.org/works/10.1016/J.TCB.2011.06.005

The epithelial-mesenchymal transition generates cells with properties of stem cells

7 December 2024

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A role for the epithelial microenvironment at tumor boundaries: evidence from Drosophila and human squamous cell carcinomas.

7 December 2024

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Self-organizing optic-cup morphogenesis in three-dimensional culture

7 December 2024

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https://api.crossref.org/works/10.1016/J.TCB.2011.06.005

Invasive three-dimensional organotypic neoplasia from multiple normal human epithelia

7 December 2024

1 reference

https://api.crossref.org/works/10.1016/J.TCB.2011.06.005

Morphogenetic mechanisms of epithelial tubulogenesis: MDCK cell polarity is transiently rearranged without loss of cell-cell contact during scatter factor/hepatocyte growth factor-induced tubulogenesis.

7 December 2024

1 reference

https://api.crossref.org/works/10.1016/J.TCB.2011.06.005

Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures

7 December 2024

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https://api.crossref.org/works/10.1016/J.TCB.2011.06.005

Cell-polarity dynamics controls the mechanism of lumen formation in epithelial morphogenesis

7 December 2024

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https://api.crossref.org/works/10.1016/J.TCB.2011.06.005

Par-3 controls tight junction assembly through the Rac exchange factor Tiam1.

7 December 2024

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7 December 2024

Identifiers

DOI

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25 August 2017

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