The transcriptional and signalling networks of pluripotency (Q37871828)

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scientific article published on May 2011

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English	The transcriptional and signalling networks of pluripotency	scientific article published on May 2011

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instance of

scholarly article

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stated in

Europe PubMed Central

PubMed publication ID

21540844

retrieved

24 August 2017

review article

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stated in

Europe PubMed Central

title

The transcriptional and signalling networks of pluripotency (English)

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stated in

Europe PubMed Central

PubMed publication ID

21540844

retrieved

24 August 2017

main subject

pluripotency

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based on heuristic

inferred from title

author

Azim Surani

series ordinal

2

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stated in

Europe PubMed Central

PubMed publication ID

21540844

retrieved

24 August 2017

Huck Hui Ng

series ordinal

1

object named as

Huck-Hui Ng

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stated in

Europe PubMed Central

PubMed publication ID

21540844

retrieved

24 August 2017

publication date

1 May 2011

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stated in

Europe PubMed Central

PubMed publication ID

21540844

retrieved

24 August 2017

published in

Nature Cell Biology

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stated in

Europe PubMed Central

PubMed publication ID

21540844

retrieved

24 August 2017

volume

13

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stated in

Europe PubMed Central

PubMed publication ID

21540844

retrieved

24 August 2017

issue

5

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stated in

Europe PubMed Central

PubMed publication ID

21540844

retrieved

24 August 2017

page(s)

490-496

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stated in

Europe PubMed Central

PubMed publication ID

21540844

retrieved

24 August 2017

cites work

A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

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The miR-430/427/302 family controls mesendodermal fate specification via species-specific target selection

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulators of the cohesin network

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptides

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sequence-specific regulator Prdm14 safeguards mouse ESCs from entering extraembryonic endoderm fates

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reprogramming of human somatic cells to pluripotency with defined factors

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stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular coupling of Xist regulation and pluripotency.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Jarid2/Jumonji coordinates control of PRC2 enzymatic activity and target gene occupancy in pluripotent cells

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

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inferred from PubMed ID database lookup

Core transcriptional regulatory circuitry in human embryonic stem cells

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

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Selective blockade of microRNA processing by Lin28

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A core Klf circuitry regulates self-renewal of embryonic stem cells.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Generation of Rat and Human Induced Pluripotent Stem Cells by Combining Genetic Reprogramming and Chemical Inhibitors

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ronin/Hcf-1 binds to a hyperconserved enhancer element and regulates genes involved in the growth of embryonic stem cells

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/21540844

retrieved

12 December 2020

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inferred from PubMed ID database lookup

Chromatin in pluripotent embryonic stem cells and differentiation

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Embryonic germ cells from mice and rats exhibit properties consistent with a generic pluripotent ground state.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TGFbeta/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An extended transcriptional network for pluripotency of embryonic stem cells

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evolution of the mammalian transcription factor binding repertoire via transposable elements

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PRDM14 suppresses expression of differentiation marker genes in human embryonic stem cells.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nanog is the gateway to the pluripotent ground state.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Integration of external signaling pathways with the core transcriptional network in embryonic stem cells

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Embryonic stem cell lines derived from human blastocysts

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stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells.

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Establishment in culture of pluripotential cells from mouse embryos

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The miR-290-295 cluster promotes pluripotency maintenance by regulating cell cycle phase distribution in mouse embryonic stem cells

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sall4 regulates distinct transcription circuitries in different blastocyst-derived stem cell lineages.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

based on heuristic

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Metastable pluripotent states in NOD-mouse-derived ESCs

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

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inferred from PubMed ID database lookup

Nanog safeguards pluripotency and mediates germline development

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oct4 and LIF/Stat3 additively induce Krüppel factors to sustain embryonic stem cell self-renewal.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

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inferred from PubMed ID database lookup

Embryonic stem cell lines from human blastocysts: somatic differentiation in vitro

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

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Conserved and divergent roles of FGF signaling in mouse epiblast stem cells and human embryonic stem cells

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

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Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Large intergenic non-coding RNA-RoR modulates reprogramming of human induced pluripotent stem cells

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sall4 modulates embryonic stem cell pluripotency and early embryonic development by the transcriptional regulation of Pou5f1

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stat3 activation is limiting for reprogramming to ground state pluripotency.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activin A maintains pluripotency of human embryonic stem cells in the absence of feeder layers

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of PI3K/AKT, MAPK/ERK and NFkappabeta signalling in the maintenance of human embryonic stem cell pluripotency and viability highlighted by transcriptional profiling and functional analysis.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

based on heuristic

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Embryonic stem cell-specific microRNAs regulate the G1-S transition and promote rapid proliferation

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

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Identification of Pou5f1, Sox2, and Nanog downstream target genes with statistical confidence by applying a novel algorithm to time course microarray and genome-wide chromatin immunoprecipitation data.

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

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A murine ESC-like state facilitates transgenesis and homologous recombination in human pluripotent stem cells.

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

based on heuristic

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Critical function of Prdm14 for the establishment of the germ cell lineage in mice

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A genome-wide RNAi screen identifies a new transcriptional module required for self-renewal

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induced pluripotent stem cell lines derived from human somatic cells

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

based on heuristic

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A genome-wide screen in EpiSCs identifies Nr5a nuclear receptors as potent inducers of ground state pluripotency.

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

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Basic FGF and suppression of BMP signaling sustain undifferentiated proliferation of human ES cells

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

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FGF stimulation of the Erk1/2 signalling cascade triggers transition of pluripotent embryonic stem cells from self-renewal to lineage commitment

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12 December 2020

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Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells

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https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

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Opposing microRNA families regulate self-renewal in mouse embryonic stem cells

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

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Jarid2 and PRC2, partners in regulating gene expression

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

based on heuristic

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BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

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A Myc network accounts for similarities between embryonic stem and cancer cell transcription programs

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PubMed

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12 December 2020

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Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells

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12 December 2020

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Revealing a core signaling regulatory mechanism for pluripotent stem cell survival and self-renewal by small molecules

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12 December 2020

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Dynamic equilibrium and heterogeneity of mouse pluripotent stem cells with distinct functional and epigenetic states

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12 December 2020

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ChIP-Seq of transcription factors predicts absolute and differential gene expression in embryonic stem cells

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PubMed

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12 December 2020

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Reprogramming of fibroblasts into induced pluripotent stem cells with orphan nuclear receptor Esrrb.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

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inferred from PubMed ID database lookup

Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

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An Oct4-centered protein interaction network in embryonic stem cells

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

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inferred from PubMed ID database lookup

An RNAi screen of chromatin proteins identifies Tip60-p400 as a regulator of embryonic stem cell identity.

1 reference

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https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

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Klf4 reverts developmentally programmed restriction of ground state pluripotency

1 reference

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https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

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inferred from PubMed ID database lookup

Mediator and cohesin connect gene expression and chromatin architecture

1 reference

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12 December 2020

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Derivation of pluripotent epiblast stem cells from mammalian embryos

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https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Nuclear Receptor Nr5a2 Can Replace Oct4 in the Reprogramming of Murine Somatic Cells to Pluripotent Cells

1 reference

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reference URL

https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reciprocal transcriptional regulation of Pou5f1 and Sox2 via the Oct4/Sox2 complex in embryonic stem cells

1 reference

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https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

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The ground state of embryonic stem cell self-renewal

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https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NANOG is a direct target of TGFbeta/activin-mediated SMAD signaling in human ESCs

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/21540844

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

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Transposable elements have rewired the core regulatory network of human embryonic stem cells

1 reference

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https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activin/Nodal and FGF pathways cooperate to maintain pluripotency of human embryonic stem cells.

1 reference

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https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epiblast stem cell subpopulations represent mouse embryos of distinct pregastrulation stages.

1 reference

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https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

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Human embryonic stem cells with biological and epigenetic characteristics similar to those of mouse ESCs

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12 December 2020

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Polycomb-like 2 associates with PRC2 and regulates transcriptional networks during mouse embryonic stem cell self-renewal and differentiation

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12 December 2020

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Regulatory networks in embryo-derived pluripotent stem cells

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dissecting self-renewal in stem cells with RNA interference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Jmjd1a and Jmjd2c histone H3 Lys 9 demethylases regulate self-renewal in embryonic stem cells

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/21540844

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/21540844

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/21540844

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators.

1 reference

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12 December 2020

based on heuristic

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Nodal inhibits differentiation of human embryonic stem cells along the neuroectodermal default pathway.

1 reference

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https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

based on heuristic

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Jumonji modulates polycomb activity and self-renewal versus differentiation of stem cells

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

based on heuristic

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Screening for novel regulators of embryonic stem cell identity

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New cell lines from mouse epiblast share defining features with human embryonic stem cells

1 reference

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https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MEK/ERK signaling contributes to the maintenance of human embryonic stem cell self-renewal

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epigenetic reversion of post-implantation epiblast to pluripotent embryonic stem cells

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/21540844

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activin/Nodal signalling maintains pluripotency by controlling Nanog expression.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/21540844

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The transcriptional foundation of pluripotency

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/21540844

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A protein interaction network for pluripotency of embryonic stem cells

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/21540844

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tcf3 is an integral component of the core regulatory circuitry of embryonic stem cells

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/21540844

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Naive and primed pluripotent states

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/21540844

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/21540844

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12 December 2020

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Identifiers

DOI

10.1038/NCB0511-490

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21540844

retrieved

24 August 2017

PubMed publication ID

21540844

1 reference

stated in

Europe PubMed Central

PubMed publication ID

21540844

retrieved

24 August 2017

ResearchGate publication ID

51096674

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