Current Strategies in The Discovery of Small-Molecule Biomarkers for Alzheimer’s Disease (Q37876426)

24 August 2017

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title

Current strategies in the discovery of small-molecule biomarkers for Alzheimer's disease (English)

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24 August 2017

Current Strategies in The Discovery of Small-Molecule Biomarkers for Alzheimer’s Disease (English)

1 reference

2 December 2024

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Luke Whiley

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21585307

2 December 2024

Cristina Legido-Quigley

series ordinal

object named as

Cristina Legido-Quigley

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21585307

2 December 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21585307

2 December 2024

publication date

1 May 2011

1 reference

24 August 2017

May 2011

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21585307

full work available at URL

2 December 2024

https://www.tandfonline.com/doi/pdf/10.4155/bio.11.62

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2 December 2024

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24 August 2017

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24 August 2017

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24 August 2017

page(s)

1121-1142

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24 August 2017

1 reference

Current concepts in Alzheimer's disease: a multidisciplinary review

21 January 2018

1 reference

Global prevalence of dementia: a Delphi consensus study

21 January 2018

1 reference

21 January 2018

1 reference

Long-term cognitive and functional decline in late onset Alzheimer's disease: therapeutic implications.

21 January 2018

1 reference

Metabolomics by numbers: acquiring and understanding global metabolite data

21 January 2018

1 reference

Parallel analysis of transcript and metabolic profiles: a new approach in systems biology

21 January 2018

1 reference

Changes in metabolite ratios after treatment with rivastigmine in Alzheimer's disease: a nonrandomised controlled trial with magnetic resonance spectroscopy

21 January 2018

1 reference

Increased glutamate in the hippocampus after galantamine treatment for Alzheimer disease

21 January 2018

1 reference

Levels of tau phosphorylation at different sites in Alzheimer disease brain

21 January 2018

1 reference

F4-isoprostanes as specific marker of docosahexaenoic acid peroxidation in Alzheimer's disease

21 January 2018

1 reference

Acrolein is increased in Alzheimer's disease brain and is toxic to primary hippocampal cultures

21 January 2018

1 reference

Proton magnetic resonance spectroscopy can differentiate Alzheimer's disease from normal aging

21 January 2018

1 reference

Magnetic resonance spectroscopy performance for detection of dementia, Alzheimer's disease and mild cognitive impairment in a community-based survey

21 January 2018

1 reference

CSF diagnosis of Alzheimer's disease and dementia with Lewy bodies.

21 January 2018

1 reference

A panel of cerebrospinal fluid potential biomarkers for the diagnosis of Alzheimer's disease.

21 January 2018

1 reference

Diagnostic performance of a CSF-biomarker panel in autopsy-confirmed dementia.

21 January 2018

1 reference

Identification of disease markers in human cerebrospinal fluid using lipidomic and proteomic methods

21 January 2018

1 reference

Large-scale, multicenter study of cerebrospinal fluid tau protein phosphorylated at serine 199 for the antemortem diagnosis of Alzheimer's disease

21 January 2018

1 reference

Cerebrospinal fluid steroidomics: are bioactive bile acids present in brain?

21 January 2018

1 reference

Study of plasma antioxidant status in Alzheimer's disease

21 January 2018

1 reference

Plasma biomarkers of Alzheimer's disease

21 January 2018

1 reference

Proteome-based plasma biomarkers for Alzheimer's disease

21 January 2018

1 reference

Increased urinary F(2)-isoprostanes levels in the patients with Alzheimer's disease.

21 January 2018

1 reference

Increased levels of truncated nerve growth factor receptor in urine of mildly demented patients with Alzheimer's disease.

21 January 2018

1 reference

Biochemical assay for AD7C-NTP in urine as an Alzheimer's disease marker.

21 January 2018

1 reference

Microvascular injury and blood-brain barrier leakage in Alzheimer's disease

21 January 2018

1 reference

The blood-brain barrier and cerebrovascular pathology in Alzheimer's disease

21 January 2018

1 reference

Vascular Basement Membrane Pathology and Alzheimer's Disease

21 January 2018

1 reference

Magnetic resonance spectroscopy

21 January 2018

1 reference

Brain membrane phospholipid alterations in Alzheimer's disease

21 January 2018

1 reference

N-acetylaspartate in neuropsychiatric disorders

21 January 2018

1 reference

Regional metabolic alterations in Alzheimer's disease: an in vitro 1H NMR study of the hippocampus and cerebellum

21 January 2018

1 reference

Probable Alzheimer disease: diagnosis with proton MR spectroscopy

21 January 2018

1 reference

Brain metabolite concentration and dementia severity in Alzheimer's disease: a (1)H MRS study

21 January 2018

1 reference

1H MR spectroscopy using TE averaged PRESS: a more sensitive technique to detect neurodegeneration associated with Alzheimer's disease

21 January 2018

1 reference

Regional metabolic patterns in mild cognitive impairment and Alzheimer's disease: A 1H MRS study

21 January 2018

1 reference

Regional N-acetylaspartate reduction in the hippocampus detected with fast proton magnetic resonance spectroscopic imaging in patients with Alzheimer disease

21 January 2018

1 reference

In vivo proton magnetic resonance spectroscopy of the temporal lobe in Alzheimer's disease

21 January 2018

1 reference

Alzheimer disease: postmortem neuropathologic correlates of antemortem 1H MR spectroscopy metabolite measurements

21 January 2018

1 reference

Alzheimer disease: depiction of increased cerebral myo-inositol with proton MR spectroscopy

21 January 2018

1 reference

Cognitive impairment: classification by 1H magnetic resonance spectroscopy.

21 January 2018

1 reference

Global analyses of cellular lipidomes directly from crude extracts of biological samples by ESI mass spectrometry: a bridge to lipidomics

21 January 2018

1 reference

Neurosteroids: Cerebrospinal Fluid Levels for Alzheimer’s Disease and Vascular Dementia Diagnostics

21 January 2018

1 reference

Increased brain levels of 4-hydroxy-2-nonenal glutathione conjugates in severe Alzheimer's disease

21 January 2018

1 reference

Determination of isoprostanes in urine samples from Alzheimer patients using porous graphitic carbon liquid chromatography–tandem mass spectrometry

21 January 2018

1 reference

Plasmalogen deficiency in early Alzheimer's disease subjects and in animal models: molecular characterization using electrospray ionization mass spectrometry

21 January 2018

1 reference

Metabolic and functional aspects of sulfogalactolipids

21 January 2018

1 reference

Substantial sulfatide deficiency and ceramide elevation in very early Alzheimer's disease: potential role in disease pathogenesis

21 January 2018

1 reference

Improving LC–MS sensitivity through increases in chromatographic performance: Comparisons of UPLC–ES/MS/MS to HPLC–ES/MS/MS

21 January 2018

1 reference

Glucose metabolism and insulin receptor signal transduction in Alzheimer disease

21 January 2018

1 reference

Brain glucose and energy metabolism abnormalities in sporadic Alzheimer disease. Causes and consequences: an update

21 January 2018

1 reference

Energy, oxidative damage, and Alzheimer's disease: clues to the underlying puzzle

21 January 2018

1 reference

Abnormal substrate levels that depend upon mitochondrial function in cerebrospinal fluid from Alzheimer patients

21 January 2018

1 reference

Oxidative imbalance in Alzheimer's disease

21 January 2018

1 reference

Cerebrospinal fluid F2-isoprostane levels are increased in Alzheimer's disease

21 January 2018

1 reference

Increased CSF F2-isoprostane concentration in probable AD.

21 January 2018

1 reference

Hydroxyoctadecadienoic acid and oxidatively modified peroxiredoxins in the blood of Alzheimer's disease patients and their potential as biomarkers.

21 January 2018

1 reference

Increased oxidative damage in nuclear and mitochondrial DNA in Alzheimer's disease

21 January 2018

1 reference

Oxidative stress-mediated DHEA formation in Alzheimer's disease pathology

21 January 2018

1 reference

Increased total 7 alpha-hydroxy-dehydroepiandrosterone in serum of patients with Alzheimer's disease

21 January 2018

1 reference

Greasing the wheels of Abeta clearance in Alzheimer's disease: the role of lipids and apolipoprotein E.

21 January 2018

1 reference

Protein glycation, oxidation and nitration adduct residues and free adducts of cerebrospinal fluid in Alzheimer's disease and link to cognitive impairment

21 January 2018

1 reference

Oxidative stress and oxidative DNA damage is characteristic for mixed Alzheimer disease/vascular dementia

21 January 2018

1 reference

Plasma antioxidants are similarly depleted in mild cognitive impairment and in Alzheimer's disease.

21 January 2018

1 reference

Decreased monoamine metabolites in frontotemporal dementia and Alzheimer's disease

21 January 2018

1 reference

Evidence that brain tissue volumes are associated with HVA reactivity to metabolic stress in schizophrenia

21 January 2018

1 reference

Glycerophosphocholine is elevated in cerebrospinal fluid of Alzheimer patients

21 January 2018

1 reference

Discovery of biomarkers in human urine and cerebrospinal fluid by capillary electrophoresis coupled to mass spectrometry: towards new diagnostic and therapeutic approaches

21 January 2018

1 reference

Simultaneous analysis by capillary electrophoresis of five amyloid peptides as potential biomarkers of Alzheimer's disease.

21 January 2018

1 reference

CE can identify small molecules that selectively target soluble oligomers of amyloid beta protein and display antifibrillogenic activity

21 January 2018

1 reference

Free D-aspartate and D-alanine in normal and Alzheimer brain

21 January 2018

1 reference

Quinolinic acid reduces the antioxidant defenses in cerebral cortex of young rats

21 January 2018

1 reference

The role of kynurenines in disorders of the central nervous system: possibilities for neuroprotection

21 January 2018

1 reference

Implications of the kynurenine pathway and quinolinic acid in Alzheimer's disease

21 January 2018

1 reference

Plasma levels of 8-epiPGF2alpha, an in vivo marker of oxidative stress, are not affected by aging or Alzheimer's disease.

21 January 2018

1 reference

Alzheimer's disease: pathophysiological implications of measurement of plasma cortisol, plasma dehydroepiandrosterone sulfate, and lymphocytic corticosteroid receptors

21 January 2018

1 reference

Systems biology: Metabonomics

21 January 2018

1 reference

Chemometrics in metabolomics--a review in human disease diagnosis

21 January 2018

1 reference

Metabonomics in pharmaceutical R&D.

21 January 2018

1 reference

Human metabolic phenotype diversity and its association with diet and blood pressure.

21 January 2018

1 reference

Metabolic profiling of plasma from discordant schizophrenia twins: correlation between lipid signals and global functioning in female schizophrenia patients.

21 January 2018

1 reference

Metabolic profiling of CSF: evidence that early intervention may impact on disease progression and outcome in schizophrenia

21 January 2018

1 reference

Metabonomic analysis identifies molecular changes associated with the pathophysiology and drug treatment of bipolar disorder

21 January 2018

1 reference

NMR spectroscopy of human post mortem cerebrospinal fluid: distinction of Alzheimer's disease from control using pattern recognition and statistics.

21 January 2018

1 reference

A multi-metabolite analysis of serum by 1H NMR spectroscopy: early systemic signs of Alzheimer's disease

21 January 2018

1 reference

Conversion from mild cognitive impairment to probable Alzheimer's disease predicted by brain magnetic resonance spectroscopy

21 January 2018

1 reference

A metabolomic study of the CRND8 transgenic mouse model of Alzheimer's disease

21 January 2018

1 reference

Association of plasma clusterin concentration with severity, pathology, and progression in Alzheimer disease

21 January 2018

1 reference

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

21 January 2018

1 reference

The effect of preanalytical factors on stability of the proteome and selected metabolites in cerebrospinal fluid (CSF).

21 January 2018

1 reference

A proposed metabolic strategy for monitoring disease progression in Alzheimer's disease

21 January 2018

1 reference

Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using 1H-NMR-based metabonomics

21 January 2018

1 reference

Quantification of 1H NMR spectra of human cerebrospinal fluid: a protocol based on constrained total-line-shape analysis

21 January 2018

1 reference

Increased 8,12-iso-iPF2alpha-VI in Alzheimer's disease: correlation of a noninvasive index of lipid peroxidation with disease severity

2 December 2024

1 reference

Increased F2-isoprostanes in Alzheimer's disease: evidence for enhanced lipid peroxidation in vivo.

2 December 2024

1 reference

Oxidative stress and Alzheimer disease

2 December 2024

1 reference

Elevated CSF prostaglandin E2 levels in patients with probable AD

2 December 2024

1 reference

Suppression of longitudinal increase in CSF F2-isoprostanes in Alzheimer's disease.

2 December 2024

1 reference

Nutritional biomarkers in Alzheimer's disease: the association between carotenoids, n-3 fatty acids, and dementia severity.

2 December 2024

1 reference

Chiral separation of amino acids in biological fluids by micellar electrokinetic chromatography with laser-induced fluorescence detection.

2 December 2024

1 reference

MK-801, an N-methyl-D-aspartate receptor antagonist, blocks quinolinic acid-induced lipid peroxidation in rat corpus striatum

2 December 2024

1 reference

Widespread peroxynitrite-mediated damage in Alzheimer's disease

2 December 2024

1 reference

Serum fatty acid profiles using GC-MS and multivariate statistical analysis: potential biomarkers of Alzheimer's disease

2 December 2024

series ordinal

107

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2 December 2024

Identifiers

DOI

10.4155/BIO.11.62

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24 August 2017

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