Cellular delivery of siRNA and antisense oligonucleotides via receptor-mediated endocytosis (Q37850458)

24 August 2017

1 reference

title

Cellular delivery of siRNA and antisense oligonucleotides via receptor-mediated endocytosis (English)

1 reference

24 August 2017

Xin Ming

1 reference

24 August 2017

language of work or name

English

0 references

publication date

8 March 2011

1 reference

full work available at URL

24 August 2017

http://www.informapharmascience.com/doi/abs/10.1517/17425247.2011.561313

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21381985

http://www.tandfonline.com/doi/pdf/10.1517/17425247.2011.561313

26 November 2024

1 reference

DOI

https://api.crossref.org/works/10.1517/17425247.2011.561313

Expert Opinion on Drug Delivery

26 November 2024

published in

1 reference

24 August 2017

1 reference

24 August 2017

1 reference

24 August 2017

page(s)

435-449

1 reference

A status report on RNAi therapeutics

24 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

The promises and pitfalls of RNA-interference-based therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

RNA targeting therapeutics: molecular mechanisms of antisense oligonucleotides as a therapeutic platform

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Therapeutic potential of splice-switching oligonucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Biological barriers to therapy with antisense and siRNA oligonucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Knocking down barriers: advances in siRNA delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Regulated portals of entry into the cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Dynamin and receptor-mediated endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Membrane fusion: grappling with SNARE and SM proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Rab GTPases as coordinators of vesicle traffic

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Application of an HIV gp41-derived peptide for enhanced intracellular trafficking of synthetic gene and siRNA delivery vehicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Increased RNAi is related to intracellular release of siRNA via a covalently attached signal peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Intracellular disposition and metabolism of fluorescently-labeled unmodified and modified oligonucleotides microinjected into mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Physico-chemical requirements for cellular uptake of pAntp peptide. Role of lipid-binding affinity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Cell-penetrating peptides. A reevaluation of the mechanism of cellular uptake

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Receptor-mediated endocytosis of phosphodiester oligonucleotides in the HepG2 cell line: evidence for non-conventional intracellular trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Binding, uptake, and intracellular trafficking of phosphorothioate-modified oligodeoxynucleotides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

In vivo fate of phosphorothioate antisense oligodeoxynucleotides: predominant uptake by scavenger receptors on endothelial liver cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Mac-1 (CD11b/CD18) is an oligodeoxynucleotide-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

The biological effect of an antisense oligonucleotide depends on its route of endocytosis and trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Efficient gene silencing by delivery of locked nucleic acid antisense oligonucleotides, unassisted by transfection reagents

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

P bodies: at the crossroads of post-transcriptional pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

siRNA targeted to p53 attenuates ischemic and cisplatin-induced acute kidney injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Gene silencing of complement C5a receptor using siRNA for preventing ischemia/reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Intravenously administered short interfering RNA accumulates in the kidney and selectively suppresses gene function in renal proximal tubules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Inhibition of respiratory viruses by nasally administered siRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Systemic RNAi in C. elegans requires the putative transmembrane protein SID-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

RNA interference: a mammalian SID-1 homologue enhances siRNA uptake and gene silencing efficacy in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Mechanisms and optimization of in vivo delivery of lipophilic siRNAs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Phosphorothioate-stimulated uptake of short interfering RNA by human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Phosphorothioate-stimulated cellular uptake of siRNA: a cell culture model for mechanistic studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Delivery of siRNA to the target cell cytoplasm: photochemical internalization facilitates endosomal escape and improves silencing efficiency, in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Antisense inhibition of P-glycoprotein expression using peptide-oligonucleotide conjugates

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Insight into the mechanism of the peptide-based gene delivery system MPG: implications for delivery of siRNA into mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Vectorization of morpholino oligomers by the (R-Ahx-R)4 peptide allows efficient splicing correction in the absence of endosomolytic agents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Effective rescue of dystrophin improves cardiac function in dystrophin-deficient mice by a modified morpholino oligomer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

A fusion peptide directs enhanced systemic dystrophin exon skipping and functional restoration in dystrophin-deficient mdx mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Targeting cyclin B1 through peptide-based delivery of siRNA prevents tumour growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Efficient siRNA delivery into primary cells by a peptide transduction domain-dsRNA binding domain fusion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Self-crosslinked and reducible fusogenic peptides for intracellular delivery of siRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Cell internalization of the third helix of the Antennapedia homeodomain is receptor-independent.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Cellular uptake of unconjugated TAT peptide involves clathrin-dependent endocytosis and heparan sulfate receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Cationic TAT peptide transduction domain enters cells by macropinocytosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Cell membrane lipid rafts mediate caveolar endocytosis of HIV-1 Tat fusion proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Cell entry of arginine-rich peptides is independent of endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Steroid and lipid conjugates of siRNAs to enhance cellular uptake and gene silencing in liver cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Efficient in vivo delivery of siRNA to the liver by conjugation of alpha-tocopherol

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Systemic and specific delivery of small interfering RNAs to the liver mediated by apolipoprotein A-I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Resolution of liver cirrhosis using vitamin A-coupled liposomes to deliver siRNA against a collagen-specific chaperone

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Dynamic PolyConjugates for targeted in vivo delivery of siRNA to hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Targeted delivery of siRNA to hepatocytes and hepatic stellate cells by bioconjugation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Intracellular delivery of an anionic antisense oligonucleotide via receptor-mediated endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Cellular delivery and biological activity of antisense oligonucleotides conjugated to a targeted protein carrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

A peptide-targeted delivery system with pH-sensitive amphiphilic cell membrane disruption for efficient receptor-mediated siRNA delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Intracellular delivery of an antisense oligonucleotide via endocytosis of a G protein-coupled receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Synthesis and Characterization of a Peptide Nucleic Acid Conjugated to a d-Peptide Analog of Insulin-like Growth Factor 1 for Increased Cellular Uptake

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Insulin receptor substrate 1 knockdown in human MCF7 ER+ breast cancer cells by nuclease-resistant IRS1 siRNA conjugated to a disulfide-bridged D-peptide analogue of insulin-like growth factor 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Induction of apoptosis in murine neuroblastoma by systemic delivery of transferrin-shielded siRNA polyplexes for downregulation of Ran.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

EGF receptor-targeted synthetic double-stranded RNA eliminates glioblastoma, breast cancer, and adenocarcinoma tumors in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Transvascular delivery of small interfering RNA to the central nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Selective gene silencing in activated leukocytes by targeting siRNAs to the integrin lymphocyte function-associated antigen-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

T cell-specific siRNA delivery suppresses HIV-1 infection in humanized mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Systemic leukocyte-directed siRNA delivery revealing cyclin D1 as an anti-inflammatory target

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Tumor-targeting nanoimmunoliposome complex for short interfering RNA delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

RNAi-mediated CCR5 silencing by LFA-1-targeted nanoparticles prevents HIV infection in BLT mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Aptamers as therapeutics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Aptamer mediated siRNA delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Systemic administration of optimized aptamer-siRNA chimeras promotes regression of PSMA-expressing tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Selection, characterization and application of new RNA HIV gp 120 aptamers for facile delivery of Dicer substrate siRNAs into HIV infected cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Novel dual inhibitory function aptamer-siRNA delivery system for HIV-1 therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

In vivo delivery of siRNA to immune cells by conjugation to a TLR9 agonist enhances antitumor immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

21 January 2018

Mining the receptorome

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Structural diversity of G protein-coupled receptors and significance for drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Delivery of short interfering RNA using endosomolytic cell-penetrating peptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

A peptide nucleic acid (PNA) is more rapidly internalized in cultured neurons when coupled to a retro-inverso delivery peptide. The antisense activity depresses the target mRNA and protein in magnocellular oxytocin neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Cell penetrating PNA constructs regulate galanin receptor levels and modify pain transmission in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Conjugates of antisense oligonucleotides with the Tat and antennapedia cell-penetrating peptides: effects on cellular uptake, binding to target sequences, and biologic actions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Cell-penetrating peptide conjugates of peptide nucleic acids (PNA) as inhibitors of HIV-1 Tat-dependent trans-activation in cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Highly efficient small interfering RNA delivery to primary mammalian neurons induces MicroRNA-like effects before mRNA degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

A stearylated CPP for delivery of splice correcting oligonucleotides using a non-covalent co-incubation strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

A new peptide vector for efficient delivery of oligonucleotides into mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

The systemic delivery of siRNAs by a cell penetrating peptide, low molecular weight protamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Targeting peptide nucleic acid (PNA) oligomers to mitochondria within cells by conjugation to lipophilic cations: implications for mitochondrial DNA replication, expression and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Silencing of microRNAs in vivo with 'antagomirs'

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Lactosylated poly(ethylene glycol)-siRNA conjugate through acid-labile beta-thiopropionate linkage to construct pH-sensitive polyion complex micelles achieving enhanced gene silencing in hepatoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Targeted intracellular delivery of antisense oligonucleotides via conjugation with small-molecule ligands.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Efficient oncogene silencing and metastasis inhibition via systemic delivery of siRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

LHRH receptor-mediated delivery of siRNA using polyelectrolyte complex micelles self-assembled from siRNA-PEG-LHRH conjugate and PEI.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

SnapShot: endocytic trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Visualizing a Correlation between siRNA Localization, Cellular Uptake, and RNAi in Living Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Cellular Uptake of PNA−Terpyridine Conjugates and Its Enhancement by Zn2+Ions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425247.2011.561313

Breaking down the barriers: siRNA delivery and endosome escape

21 January 2018

1 reference

https://api.crossref.org/works/10.1517/17425247.2011.561313

Cellular uptake and subcellular distribution of phosphorothioate oligonucleotides into cultured cells

26 November 2024

1 reference

https://api.crossref.org/works/10.1517/17425247.2011.561313

Uptake characteristics of oligonucleotides in the isolated rat liver perfusion system

26 November 2024

1 reference

https://api.crossref.org/works/10.1517/17425247.2011.561313

Antisense oligonucleotide pharmacokinetics and metabolism

26 November 2024

1 reference

https://api.crossref.org/works/10.1517/17425247.2011.561313

Liver uptake of phosphodiester oligodeoxynucleotides is mediated by scavenger receptors

26 November 2024

1 reference

https://api.crossref.org/works/10.1517/17425247.2011.561313

Efficient In Vivo Delivery of siRNA to the Liver by Conjugation of α-Tocopherol

26 November 2024

1 reference

https://api.crossref.org/works/10.1517/17425247.2011.561313

The asialoglycoprotein receptor: relationships between structure, function, and expression

26 November 2024

1 reference

https://api.crossref.org/works/10.1517/17425247.2011.561313

Targeted delivery of oligodeoxynucleotides to parenchymal liver cells in vivo.

26 November 2024

1 reference

https://api.crossref.org/works/10.1517/17425247.2011.561313

Design of a targeted peptide nucleic acid prodrug to inhibit hepatic human microsomal triglyceride transfer protein expression in hepatocytes

26 November 2024

1 reference

https://api.crossref.org/works/10.1517/17425247.2011.561313

Small interfering RNA delivery to the liver by intravenous administration of galactosylated cationic liposomes in mice

26 November 2024

1 reference

https://api.crossref.org/works/10.1517/17425247.2011.561313

Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors

26 November 2024

1 reference

https://api.crossref.org/works/10.1517/17425247.2011.561313

26 November 2024

Molecular Pharmacology

431

Pichon C

1997

1 reference

DOI

https://api.crossref.org/works/10.1517/17425247.2011.561313

26 November 2024

Identifiers

DOI

1 reference

24 August 2017

1 reference