Developing vaccines to combat hookworm infection and intestinal schistosomiasis (Q37800361)

23 August 2017

title

Developing vaccines to combat hookworm infection and intestinal schistosomiasis (English)

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23 August 2017

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23 August 2017

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23 August 2017

Mark Pearson

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David J Diemert

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Jeffrey M Bethony

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23 August 2017

language of work or name

English

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publication date

1 November 2010

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Nature Reviews Microbiology

23 August 2017

published in

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23 August 2017

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23 August 2017

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23 August 2017

page(s)

814-826

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on focus list of Wikimedia project

23 August 2017

ScienceSource

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The public health importance of hookworm disease

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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Elimination of helminth infection restores HIV-1C vaccine-specific T cell responses independent of helminth-induced IL-10

31 March 2020

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The helminth HIV connection: time to act.

31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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Unresolved issues in anthelmintic pharmacology for helminthiases of humans

31 March 2020

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31 March 2020

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Rate of reinfection with intestinal nematodes after treatment of children with mebendazole or albendazole in a highly endemic area.

31 March 2020

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31 March 2020

The antipoverty vaccines

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Hookworm vaccines: past, present, and future

31 March 2020

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Vaccines against blood-feeding nematodes of humans and livestock

31 March 2020

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31 March 2020

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Model for product development of vaccines against neglected tropical diseases: a vaccine against human hookworm

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Neglected tropical disease vaccines

31 March 2020

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Trick or treat: the role of vaccines in integrated schistosomiasis control

31 March 2020

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Deletion of the intestinal peptide transporter affects insulin and TOR signaling in Caenorhabditis elegans

31 March 2020

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Metabolism of lipid peroxidation products by the gastro-intestinal nematodes Necator americanus, Ancylostoma ceylanicum and Heligmosomoides polygyrus

31 March 2020

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Molecular cloning and purification of Ac-TMP, a developmentally regulated putative tissue inhibitor of metalloprotease released in relative abundance by adult Ancylostoma hookworms.

31 March 2020

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Glutathione S-transferase from malarial parasites: structural and functional aspects

31 March 2020

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HDP-a novel heme detoxification protein from the malaria parasite

31 March 2020

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X-ray structures of Na-GST-1 and Na-GST-2 two glutathione s-transferase from the human hookworm Necator americanus

31 March 2020

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Binding of hematin by a new class of glutathione transferase from the blood-feeding parasitic nematode Haemonchus contortus

31 March 2020

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Crystal structure of a new class of glutathione transferase from the model human hookworm nematode Heligmosomoides polygyrus.

31 March 2020

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The evaluation of recombinant hookworm antigens as vaccines in hamsters (Mesocricetus auratus) challenged with human hookworm, Necator americanus

31 March 2020

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Evaluation of Wuchereria bancrofti GST as a vaccine candidate for lymphatic filariasis

31 March 2020

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An enzymatically inactivated hemoglobinase from Necator americanus induces neutralizing antibodies against multiple hookworm species and protects dogs against heterologous hookworm infection

31 March 2020

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Recent progress in the development of plant derived vaccines

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Vaccination with recombinant aspartic hemoglobinase reduces parasite load and blood loss after hookworm infection in dogs

31 March 2020

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Neutralizing antibodies to the hookworm hemoglobinase Na-APR-1: implications for a multivalent vaccine against hookworm infection and schistosomiasis

31 March 2020

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A survey of the intestinal transcriptomes of the hookworms, Necator americanus and Ancylostoma caninum, using tissues isolated by laser microdissection microscopy.

31 March 2020

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The intestinal contortin structure in Haemonchus contortus: an immobilised anticoagulant?

31 March 2020

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Antibodies against a secreted protein from hookworm larvae reduce the intensity of hookworm infection in humans and vaccinated laboratory animals

31 March 2020

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Expression of the Necator americanus hookworm larval antigen Na-ASP-2 in Pichia pastoris and purification of the recombinant protein for use in human clinical trials

31 March 2020

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Immunogenicity of the hookworm Na-ASP-2 vaccine candidate: characterization of humoral and cellular responses after vaccination in the Sprague Dawley rat.

31 March 2020

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Vaccination with irradiated Ancylostoma caninum third stage larvae induces a Th2 protective response in dogs

31 March 2020

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Current status of vaccines for schistosomiasis

31 March 2020

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Transmission control for schistosomiasis - why it matters now.

31 March 2020

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Recent advances in vaccine research against schistosomiasis in Brazil

31 March 2020

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Natural versus drug-induced resistance in Schistosoma mansoni infection

31 March 2020

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Schistosomes: the road from host-parasite interactions to vaccines in clinical trials

31 March 2020

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The biotechnology-value chain: development of Sm14 as a schistosomiasis vaccine

31 March 2020

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Sm-p80-based DNA vaccine provides baboons with levels of protection against Schistosoma mansoni infection comparable to those achieved by the irradiated cercarial vaccine

31 March 2020

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Pilot-scale production and characterization of paramyosin, a vaccine candidate for schistosomiasis japonica

31 March 2020

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Schistosome membrane proteins as vaccines

31 March 2020

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Tetraspanins on the surface of Schistosoma mansoni are protective antigens against schistosomiasis

31 March 2020

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Human antibody responses of patients living in endemic areas for schistosomiasis to the tegumental protein Sm29 identified through genomic studies.

31 March 2020

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Schistosoma mansoni tegument protein Sm29 is able to induce a Th1-type of immune response and protection against parasite infection

31 March 2020

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Schistosoma japonicum: efficient and rapid purification of the tetraspanin extracellular loop 2, a potential protective antigen against schistosomiasis in mammalian.

31 March 2020

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Suppression of mRNAs encoding tegument tetraspanins from Schistosoma mansoni results in impaired tegument turnover

31 March 2020

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Transcriptional changes in Schistosoma mansoni during early schistosomula development and in the presence of erythrocytes

31 March 2020

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Anti-schistosomal intervention targets identified by lifecycle transcriptomic analyses

31 March 2020

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DNA-based vaccines protect against zoonotic schistosomiasis in water buffalo

31 March 2020

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Health Innovation Networks to Help Developing Countries Address Neglected Diseases

31 March 2020

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Helminth parasites--masters of regulation

31 March 2020

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Vaccination against helminth parasites--the ultimate challenge for vaccinologists?

31 March 2020

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Emerging Patterns of Hookworm Infection: Influence of Aging on the Intensity ofNecatorInfection in Hainan Province, People’s Republic of China

31 March 2020

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Schistosomiasis and liver fibrosis

31 March 2020

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Helminths, allergic disorders and IgE-mediated immune responses: where do we stand?

31 March 2020

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The spread, treatment, and prevention of HIV-1: evolution of a global pandemic

31 March 2020

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Malaria: progress, perils, and prospects for eradication

31 March 2020

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The burden of malaria mortality among African children in the year 2000.

31 March 2020

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The global distribution of clinical episodes of Plasmodium falciparum malaria

31 March 2020

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Veterinary parasitic vaccines: pitfalls and future directions

31 March 2020

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Dictyocaulus viviparus: re-emerging or never been away?

31 March 2020

1 reference

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Vaccine development and diagnostics of Dictyocaulus viviparus

31 March 2020

1 reference

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The nature and prospects for gut membrane proteins as vaccine candidates for Haemonchus contortus and other ruminant trichostrongyloids

31 March 2020

1 reference

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Cestode vaccines: origins, current status and future prospects.

31 March 2020

1 reference

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Consequences of Schistosoma haematobium infection on the iron status of schoolchildren in Niger

31 March 2020

1 reference

12 December 2020

Industrial Development and Field Use of the Canine Hookworm Vaccine

1 reference

12 December 2020

Relationships of Schistosoma haematobium, hookworm and malarial infections and metrifonate treatment to growth of Kenyan school children

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12 December 2020

Drug resistance in human helminths: current situation and lessons from livestock

1 reference

12 December 2020

Hookworm control as a strategy to prevent iron deficiency

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12 December 2020

Efficacy of a hookworm (Ancylostoma caninum) vaccine for dogs

1 reference

12 December 2020

Soil-transmitted helminthiasis. Progress report on number of children treated with anthelminthic drugs: an update towards the 2010 global target

1 reference

12 December 2020

Assessment of public health implication of malaria-geohelminth co-infection with an emphasis on hookworm-malaria anemia among suspected malaria patients in asendabo, southwest Ethiopia

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12 December 2020

Risk factors for anemia in Vietnam.

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12 December 2020

Efficacy of mebendazole and levamisole alone or in combination against intestinal nematode infections after repeated targeted mebendazole treatment in Zanzibar

1 reference

12 December 2020

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12 December 2020

Helminth parasites, a major factor in malnutrition

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12 December 2020

Evaluation of efficacy of school-based anthelmintic treatments against anaemia in children in the United Republic of Tanzania

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12 December 2020

Field experience with the bovine lungworm vaccine

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12 December 2020

A 14-kDa Schistosoma mansoni polypeptide is homologous to a gene family of fatty acid binding proteins

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12 December 2020

Prevention and control of schistosomiasis and soil-transmitted helminthiasis

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRMICRO2438

1 reference

Dimensions Publication ID

23 August 2017

1016179719

0 references

1 reference