Molecular mechanisms underlying the control of antigenic variation in African trypanosomes (Q37795350)

23 August 2017

2 references

24 June 2020

7 July 2020

Molecular mechanisms underlying the control of antigenic variation in African trypanosomes (English)

1 reference

Trypanosoma brucei gambiense

23 August 2017

1 reference

PubMed

variable surface glycoprotein

22 October 2019

1 reference

24 June 2020

1 reference

7 July 2020

David Horn

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20884281

23 July 2024

Richard McCulloch

1 reference

23 August 2017

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20884281

23 July 2024

publication date

29 September 2010

1 reference

full work available at URL

23 August 2017

1 December 2010

7 references

30 June 2019

14 September 2019

22 October 2019

15 December 2019

28 May 2020

24 June 2020

7 July 2020

https://doi.org/10.1016/j.mib.2010.08.009

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20884281

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20884281/?tool=EBI

23 July 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20884281

https://europepmc.org/articles/PMC3117991

23 July 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20884281

https://api.elsevier.com/content/article/PII:S1369527410001232?httpAccept=text/xml

23 July 2024

1 reference

10.1016/J.MIB.2010.08.009

Crossref

DOI

https://api.crossref.org/works/10.1016/J.MIB.2010.08.009

https://api.elsevier.com/content/article/PII:S1369527410001232?httpAccept=text/plain

23 July 2024

1 reference

10.1016/J.MIB.2010.08.009

Crossref

DOI

https://api.crossref.org/works/10.1016/J.MIB.2010.08.009

Current Opinion in Microbiology

23 July 2024

published in

8 references

23 August 2017

30 June 2019

14 September 2019

22 October 2019

15 December 2019

28 May 2020

24 June 2020

7 July 2020

1 reference

23 August 2017

1 reference

23 August 2017

700-705

1 reference

Creative Commons Attribution 3.0 Unported

23 August 2017

7 references

30 June 2019

14 September 2019

22 October 2019

15 December 2019

28 May 2020

24 June 2020

Histone deacetylases play distinct roles in telomeric VSG expression site silencing in African trypanosomes.

7 July 2020

copyrighted

0 references

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117991

Alternative lengthening of telomeres: models, mechanisms and implications

6 September 2017

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Alternative end-joining catalyzes robust IgH locus deletions and translocations in the combined absence of ligase 4 and Ku70

6 September 2017

1 reference

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Bloodstream form Trypanosome plasma membrane proteins: antigenic variation and invariant antigens

6 September 2017

1 reference

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DNA resection in eukaryotes: deciding how to fix the break

6 September 2017

1 reference

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Active VSG expression sites in Trypanosoma brucei are depleted of nucleosomes

6 September 2017

1 reference

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Nucleosomes are depleted at the VSG expression site transcribed by RNA polymerase I in African trypanosomes

6 September 2017

1 reference

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The trypanosome flagellar pocket.

6 September 2017

1 reference

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Antigenic variation in the African trypanosome: molecular mechanisms and phenotypic complexity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117991

Cohesin regulates VSG monoallelic expression in trypanosomes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117991

Complex human chromosomal and genomic rearrangements

6 September 2017

1 reference

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DNA breaks as triggers for antigenic variation in African trypanosomes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117991

Transcription factories: gene expression in unions?

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117991

Histone deacetylase Rpd3 antagonizes Sir2-dependent silent chromatin propagation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117991

A yeast-endonuclease-generated DNA break induces antigenic switching in Trypanosoma brucei

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117991

RAP1 is essential for silencing telomeric variant surface glycoprotein genes in Trypanosoma brucei.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117991

A microhomology-mediated break-induced replication model for the origin of human copy number variation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117991

Telomeric expression sites are highly conserved in Trypanosoma brucei

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117991

MMEJ repair of double-strand breaks (director's cut): deleted sequences and alternative endings

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117991

Two essential MYST-family proteins display distinct roles in histone H4K10 acetylation and telomeric silencing in trypanosomes.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117991

A histone methyltransferase modulates antigenic variation in African trypanosomes.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117991

Trypanosoma brucei BRCA2 acts in antigenic variation and has undergone a recent expansion in BRC repeat number that is important during homologous recombination

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117991

Sequence homology and microhomology dominate chromosomal double-strand break repair in African trypanosomes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117991

Mechanism of eukaryotic homologous recombination

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117991

Ku heterodimer-independent end joining in Trypanosoma brucei cell extracts relies upon sequence microhomology.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117991

Break-induced replication and telomerase-independent telomere maintenance require Pol32.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117991

Analysis of the VSG gene silent archive in Trypanosoma brucei reveals that mosaic gene expression is prominent in antigenic variation and is favored by archive substructure

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117991

Deletion of a trypanosome telomere leads to loss of silencing and progressive loss of terminal DNA in the absence of cell cycle arrest

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117991

A sirtuin in the African trypanosome is involved in both DNA repair and telomeric gene silencing but is not required for antigenic variation.

6 September 2017

1 reference

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New functions for Y family polymerases

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117991

Break-induced replication and recombinational telomere elongation in yeast

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117991

Distinct roles for two RAD51-related genes in Trypanosoma brucei antigenic variation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117991

Repression of polymerase I-mediated gene expression at Trypanosoma brucei telomeres

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117991

Genome-wide analysis of HDAC function

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117991

The central roles of telomeres and subtelomeres in antigenic variation in African trypanosomes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117991

The molecular control of antigenic variation in Trypanosoma brucei

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117991

Genetic and epigenetic regulation of the FLO gene family generates cell-surface variation in yeast

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117991

Spreading of Sir3 protein in cells with severe histone H3 hypoacetylation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117991

Position effect at S. cerevisiae telomeres: reversible repression of Pol II transcription

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117991

A role for RAD51 and homologous recombination in Trypanosoma brucei antigenic variation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117991

Alternative end-joining is suppressed by the canonical NHEJ component Xrcc4-ligase IV during chromosomal translocation formation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117991

Molecular model for telomeric heterochromatin in yeast

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117991

What has DNA sequencing revealed about the VSG expression sites of African trypanosomes?

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117991

Molecular microbiology: A key event in survival

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117991

A novel ISWI is involved in VSG expression site downregulation in African trypanosomes

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117991

Trypanosoma brucei MRE11 is non-essential but influences growth, homologous recombination and DNA double-strand break repair.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117991

Two pathways of homologous recombination in Trypanosoma brucei

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117991

Inactivation of Mre11 does not affect VSG gene duplication mediated by homologous recombination in Trypanosoma brucei.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117991

A pol I transcriptional body associated with VSG mono-allelic expression in Trypanosoma brucei

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117991

Differential RNA elongation controls the variant surface glycoprotein gene expression sites of Trypanosoma brucei

3 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20884281

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Telomere structure and function in trypanosomes: a proposal

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20884281

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.MIB.2010.08.009

1 reference

23 August 2017

1 reference

23 August 2017

1 reference