The genetics of pediatric brain tumors (Q37738138)

22 August 2017

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title

The genetics of pediatric brain tumors (English)

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22 August 2017

Stefan Pfister

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Paul A Northcott

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22 August 2017

Michael D Taylor

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22 August 2017

Adrian M Dubuc

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22 August 2017

Stephen Mack

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22 August 2017

Hendrik Witt

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22 August 2017

publication date

1 May 2010

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Current Neurology and Neuroscience Reports

22 August 2017

published in

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22 August 2017

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22 August 2017

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22 August 2017

page(s)

215-223

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Wnt/Wingless pathway activation and chromosome 6 loss characterize a distinct molecular sub-group of medulloblastomas associated with a favorable prognosis.

22 August 2017

cites work

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11910-010-0103-9

Population-based studies on incidence, survival rates, and genetic alterations in astrocytic and oligodendroglial gliomas

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11910-010-0103-9

Epigenetic events in medulloblastoma development.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS11910-010-0103-9

Further evidence for a somatic KRAS mutation in a pilocytic astrocytoma.

21 January 2018

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12 December 2020

Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome

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12 December 2020

Medulloblastoma: developmental mechanisms out of control

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12 December 2020

A clinicobiological model predicting survival in medulloblastoma.

1 reference

12 December 2020

Epigenetic inactivation of DLC-1 in supratentorial primitive neuroectodermal tumor

1 reference

12 December 2020

Identification of tumor-specific molecular signatures in intracranial ependymoma and association with clinical characteristics.

1 reference

12 December 2020

Supratentorial primitive neuroectodermal tumors of the central nervous system frequently harbor deletions of the CDKN2A locus and other genomic aberrations distinct from medulloblastomas.

1 reference

12 December 2020

Genome-epigenome interactions in cancer

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12 December 2020

Distinct genetic signatures among pilocytic astrocytomas relate to their brain region origin

1 reference

12 December 2020

Genomic analysis of pilocytic astrocytomas at 0.97 Mb resolution shows an increasing tendency toward chromosomal copy number change with age.

1 reference

12 December 2020

Comparative genomic hybridization in patients with supratentorial and infratentorial primitive neuroectodermal tumors

1 reference

12 December 2020

Identification of gains on 1q and epidermal growth factor receptor overexpression as independent prognostic markers in intracranial ependymoma

1 reference

12 December 2020

Isochromosome 17q is a negative prognostic factor in poor-risk childhood medulloblastoma patients

1 reference

12 December 2020

High promoter hypermethylation frequency of p14/ARF in supratentorial PNET but not in medulloblastoma

1 reference

12 December 2020

Duplication of 7q34 in pediatric low-grade astrocytomas detected by high-density single-nucleotide polymorphism-based genotype arrays results in a novel BRAF fusion gene

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12 December 2020

Oncogenic RAF1 rearrangement and a novel BRAF mutation as alternatives to KIAA1549:BRAF fusion in activating the MAPK pathway in pilocytic astrocytoma

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12 December 2020

The genetic and epigenetic basis of ependymoma.

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12 December 2020

BRAF gene duplication constitutes a mechanism of MAPK pathway activation in low-grade astrocytomas

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12 December 2020

Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation

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12 December 2020

Genomics identifies medulloblastoma subgroups that are enriched for specific genetic alterations

1 reference

12 December 2020

Duplication of 7q34 is specific to juvenile pilocytic astrocytomas and a hallmark of cerebellar and optic pathway tumours

1 reference

12 December 2020

Molecular insight into medulloblastoma and central nervous system primitive neuroectodermal tumor biology from hereditary syndromes: a review

1 reference

12 December 2020

Molecular genetic analysis of the TP53, PTEN, CDKN2A, EGFR, CDK4 and MDM2 tumour-associated genes in supratentorial primitive neuroectodermal tumours and glioblastomas of childhood.

1 reference

12 December 2020

Candidate genes on chromosome 9q33-34 involved in the progression of childhood ependymomas.

1 reference

12 December 2020

Global analysis of the medulloblastoma epigenome identifies disease-subgroup-specific inactivation of COL1A2

1 reference

12 December 2020

Combined molecular analysis of BRAF and IDH1 distinguishes pilocytic astrocytoma from diffuse astrocytoma.

1 reference

12 December 2020

Epigenetic repression of RASSF1A but not CASP8 in supratentorial PNET (sPNET) and atypical teratoid/rhabdoid tumors (AT/RT) of childhood

1 reference

12 December 2020

High-resolution array-based comparative genomic hybridization of medulloblastomas and supratentorial primitive neuroectodermal tumors.

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12 December 2020

The molecular basis of Turcot's syndrome

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12 December 2020

Radial glia cells are candidate stem cells of ependymoma

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12 December 2020

Analysis of pilocytic astrocytoma by comparative genomic hybridization.

1 reference

12 December 2020

Activation of the ERK/MAPK pathway: a signature genetic defect in posterior fossa pilocytic astrocytomas.

1 reference

12 December 2020

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12 December 2020

Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma

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12 December 2020

Medulloblastoma in childhood: new biological advances

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12 December 2020

The origins of medulloblastoma subtypes

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12 December 2020

Genetic heterogeneity in supratentorial and infratentorial primitive neuroectodermal tumours of the central nervous system.

1 reference

12 December 2020

Risk-adapted craniospinal radiotherapy followed by high-dose chemotherapy and stem-cell rescue in children with newly diagnosed medulloblastoma (St Jude Medulloblastoma-96): long-term results from a prospective, multicentre trial

1 reference

12 December 2020

The miR-17~92 cluster collaborates with the Sonic Hedgehog pathway in medulloblastoma

1 reference

12 December 2020

Prediction of central nervous system embryonal tumour outcome based on gene expression

1 reference

12 December 2020

Outcome prediction in pediatric medulloblastoma based on DNA copy-number aberrations of chromosomes 6q and 17q and the MYC and MYCN loci

1 reference

12 December 2020

An epigenetic genome-wide screen identifies SPINT2 as a novel tumor suppressor gene in pediatric medulloblastoma

1 reference

12 December 2020

Array-based profiling of reference-independent methylation status (aPRIMES) identifies frequent promoter methylation and consecutive downregulation of ZIC2 in pediatric medulloblastoma

1 reference

12 December 2020

Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features

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12 December 2020

Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome

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12 December 2020

RAS pathway activation and an oncogenic RAS mutation in sporadic pilocytic astrocytoma

1 reference

12 December 2020

Tandem duplication producing a novel oncogenic BRAF fusion gene defines the majority of pilocytic astrocytomas

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12 December 2020

The miR-17/92 polycistron is up-regulated in sonic hedgehog-driven medulloblastomas and induced by N-myc in sonic hedgehog-treated cerebellar neural precursors

1 reference

12 December 2020

Outcome for children with supratentorial primitive neuroectodermal tumors treated with surgery, radiation, and chemotherapy

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12 December 2020

Optic pathway gliomas in neurofibromatosis-1: controversies and recommendations.

1 reference

12 December 2020

Neurofibromatosis type I tumor suppressor neurofibromin regulates neuronal differentiation via its GTPase-activating protein function toward Ras.

1 reference

12 December 2020

Frequent gains at chromosome 7q34 involving BRAF in pilocytic astrocytoma

1 reference

12 December 2020

10.1007/S11910-010-0103-9

Identifiers

DOI

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22 August 2017

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