LFA-1-mediated T cell costimulation through increased localization of TCR/class II complexes to the central supramolecular activation cluster and exclusion of CD45 from the immunological synapse (Q37712605)

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scientific article published on August 2007

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English	LFA-1-mediated T cell costimulation through increased localization of TCR/class II complexes to the central supramolecular activation cluster and exclusion of CD45 from the immunological synapse	scientific article published on August 2007

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

LFA-1-mediated T cell costimulation through increased localization of TCR/class II complexes to the central supramolecular activation cluster and exclusion of CD45 from the immunological synapse (English)

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

1 reference

based on heuristic

inferred from title

author name string

Beth Graf

1

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

Timothy Bushnell

2

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

Jim Miller

3

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

language of work or name

0 references

publication date

1 August 2007

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Europe PubMed Central

PMC publication ID

22 August 2017

Journal of Immunology

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Europe PubMed Central

PMC publication ID

22 August 2017

179

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Europe PubMed Central

PMC publication ID

22 August 2017

3

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

1616-1624

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

Integrin structures and conformational signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993012

23 August 2017

T cell receptor-proximal signals are sustained in peripheral microclusters and terminated in the central supramolecular activation cluster

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993012

23 August 2017

Immunological synapse and microclusters: the site for recognition and activation of T cells

1 reference

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23 August 2017

Immune synapses in T-cell activation

1 reference

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23 August 2017

Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling

1 reference

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23 August 2017

Tuning immune responses: diversity and adaptation of the immunological synapse.

1 reference

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23 August 2017

Intracellular signalling controlling integrin activation in lymphocytes

1 reference

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Importance of integrin LFA-1 deactivation for the generation of immune responses

1 reference

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T cell receptor (TCR) clustering in the immunological synapse integrates TCR and costimulatory signaling in selected T cells

1 reference

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The primacy of affinity over clustering in regulation of adhesiveness of the integrin {alpha}L{beta}2.

1 reference

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23 August 2017

Cutting edge: CD28-mediated transcriptional and posttranscriptional regulation of IL-2 expression are controlled through different signaling pathways

1 reference

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23 August 2017

T cell receptor antagonism interferes with MHC clustering and integrin patterning during immunological synapse formation

1 reference

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23 August 2017

Membranes as messengers in T cell adhesion signaling

1 reference

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23 August 2017

CD226 (DNAM-1) is involved in lymphocyte function-associated antigen 1 costimulatory signal for naive T cell differentiation and proliferation

1 reference

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23 August 2017

Therapeutic antagonists and conformational regulation of integrin function

1 reference

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23 August 2017

RAPL, a Rap1-binding molecule that mediates Rap1-induced adhesion through spatial regulation of LFA-1

1 reference

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23 August 2017

Targeting ICAM-1/LFA-1 interaction for controlling autoimmune diseases: designing peptide and small molecule inhibitors

1 reference

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23 August 2017

CD45: a critical regulator of signaling thresholds in immune cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993012

23 August 2017

Staging and resetting T cell activation in SMACs

1 reference

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23 August 2017

CD28 plays a critical role in the segregation of PKC theta within the immunologic synapse

1 reference

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23 August 2017

SKAP55 coupled with CD45 positively regulates T-cell receptor-mediated gene transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993012

23 August 2017

Dynamics of the immunological synapse: finding, establishing and solidifying a connection

1 reference

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23 August 2017

ERM-dependent movement of CD43 defines a novel protein complex distal to the immunological synapse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993012

23 August 2017

Exclusion of CD43 from the immunological synapse is mediated by phosphorylation-regulated relocation of the cytoskeletal adaptor moesin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993012

23 August 2017

A supramolecular basis for CD45 tyrosine phosphatase regulation in sustained T cell activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993012

23 August 2017

Integrin LFA-1 interacts with the transcriptional co-activator JAB1 to modulate AP-1 activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993012

23 August 2017

Relative contribution of LFA-1 and Mac-1 to neutrophil adhesion and migration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993012

23 August 2017

The immunological synapse: a molecular machine controlling T cell activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993012

23 August 2017

Lymphocyte migration in lymphocyte function-associated antigen (LFA)-1-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993012

23 August 2017

Intercellular adhesion molecule-1 inhibits interleukin 4 production by naive T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993012

23 August 2017

Three-dimensional segregation of supramolecular activation clusters in T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993012

23 August 2017

Spontaneous skin ulceration and defective T cell function in CD18 null mice

1 reference

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23 August 2017

Visualizing the dynamics of T cell activation: intracellular adhesion molecule 1 migrates rapidly to the T cell/B cell interface and acts to sustain calcium levels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993012

23 August 2017

Transfected Drosophila cells as a probe for defining the minimal requirements for stimulating unprimed CD8+ T cells

1 reference

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23 August 2017

Alpha L beta 2 integrin/LFA-1 binding to ICAM-1 induced by cytohesin-1, a cytoplasmic regulatory molecule

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993012

23 August 2017

LFA-1-deficient mice show normal CTL responses to virus but fail to reject immunogenic tumor

1 reference

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23 August 2017

Enhanced antigen presentation in the absence of the invariant chain endosomal localization signal

1 reference

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23 August 2017

Beta 2-integrin LFA-1 signaling through phospholipase C-gamma 1 activation

1 reference

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23 August 2017

Costimulation by purified intercellular adhesion molecule 1 and lymphocyte function-associated antigen 3 induces distinct proliferation, cytokine and cell surface antigen profiles in human "naive" and "memory" CD4+ T cells

1 reference

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23 August 2017

Analysis of T cell stimulation by superantigen plus major histocompatibility complex class II molecules or by CD3 monoclonal antibody: costimulation by purified adhesion ligands VCAM-1, ICAM-1, but not ELAM-1.

1 reference

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23 August 2017

The interaction of activated integrin lymphocyte function-associated antigen 1 with ligand intercellular adhesion molecule 1 induces activation and redistribution of focal adhesion kinase and proline-rich tyrosine kinase 2 in T lymphocytes.

1 reference

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6 September 2017

Beta2 integrins are required for skin homing of primed T cells but not for priming naive T cells

1 reference

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14 September 2017

Cytoskeletal regulation couples LFA-1 conformational changes to receptor lateral mobility and clustering

1 reference

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14 September 2017

Engagement of CD28 outside of the immunological synapse results in up-regulation of IL-2 mRNA stability but not IL-2 transcription

1 reference

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14 September 2017

T-cell receptor triggering is critically dependent on the dimensions of its peptide-MHC ligand.

1 reference

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14 September 2017

LFA-1 co-stimulation inhibits T(h)2 differentiation by down-modulating IL-4 responsiveness.

1 reference

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14 September 2017

LFA-1 on CD4+ T cells is required for optimal antigen-dependent activation in vivo

1 reference

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14 September 2017

Transient intercellular adhesion: the importance of weak protein-protein interactions

1 reference

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14 September 2017

The immunological synapse and CD28-CD80 interactions.

1 reference

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28 September 2017

Molecular mechanisms of IL-2 gene regulation following costimulation through LFA-1.

1 reference

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28 September 2017

LFA-1-mediated costimulation of CD8+ T cell proliferation requires phosphatidylinositol 3-kinase activity

1 reference

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28 September 2017

TCR, LFA-1, and CD28 play unique and complementary roles in signaling T cell cytoskeletal reorganization.

1 reference

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28 September 2017

Impaired immune responses toward alloantigens and tumor cells but normal thymic selection in mice deficient in the beta2 integrin leukocyte function-associated antigen-1.

1 reference

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28 September 2017

Polarity of T cell shape, motility, and sensitivity to antigen

1 reference

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Making the T cell receptor go the distance: a topological view of T cell activation

1 reference

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28 September 2017

Costimulatory requirements of naive CD4+ T cells. ICAM-1 or B7-1 can costimulate naive CD4 T cell activation but both are required for optimum response.

1 reference

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Detection of antigen-specific T cells with multivalent soluble class II MHC covalent peptide complexes

1 reference

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1 reference

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Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76.

1 reference

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1 September 2018

T-cell-antigen recognition and the immunological synapse

1 reference

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Highly Biased Type 1 Immune Responses in Mice Deficient in LFA-1 inListeria monocytogenesInfection Are Caused by Elevated IL-12 Production by Granulocytes

1 reference

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1 September 2018

Leukocyte functional antigen 1 lowers T cell activation thresholds and signaling through cytohesin-1 and Jun-activating binding protein 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993012

1 September 2018

The immunological synapse balances T cell receptor signaling and degradation

1 reference

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1 September 2018

Differential requirement for CD18 in T-helper effector homing

1 reference

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1 September 2018

Continuous T cell receptor signaling required for synapse maintenance and full effector potential

1 reference

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1 September 2018

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1 reference

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1 September 2018

Neutrophilia in LFA-1-Deficient Mice Confers Resistance to Listeriosis: Possible Contribution of Granulocyte-Colony-Stimulating Factor and IL-17

1 reference

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1 September 2018

Direct observation of ligand recognition by T cells.

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1 September 2018

Long-term reversal of established autoimmunity upon transient blockade of the LFA-1/intercellular adhesion molecule-1 pathway.

1 reference

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1 September 2018

The immunological synapse of CTL contains a secretory domain and membrane bridges.

1 reference

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1 September 2018

Dominant role of intercellular adhesion molecule-1 in the pathogenesis of autoimmune diabetes in non-obese diabetic mice

1 reference

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1 September 2018

Dependence of T cell antigen recognition on the dimensions of an accessory receptor-ligand complex

1 reference

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1 September 2018

ICAM-1 and B7-1 provide similar but distinct costimulation for CD8+ T cells, while CD4+ T cells are poorly costimulated by ICAM-1.

1 reference

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1 September 2018

Erratum: Costimulation and endogenous MHC ligands contribute to T cell recognition

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3 December 2018

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3 December 2018

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1 reference

https://pubmed.ncbi.nlm.nih.gov/17641028

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation through intercellular adhesion molecule-1 provides a second signal for T cell activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17641028

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD4-dependent generation of dominant transplantation tolerance induced by simultaneous perturbation of CD154 and LFA-1 pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/17641028

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Live-cell dynamics and the role of costimulation in immunological synapse formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17641028

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Absence of allograft ICAM-1 attenuates alloantigen-specific T cell priming, but not primed T cell trafficking into the graft, to mediate acute rejection

1 reference

https://pubmed.ncbi.nlm.nih.gov/17641028

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Costimulation of T cell receptor/CD3-mediated activation of resting human CD4+ T cells by leukocyte function-associated antigen-1 ligand intercellular cell adhesion molecule-1 involves prolonged inositol phospholipid hydrolysis and sustained increas

1 reference

https://pubmed.ncbi.nlm.nih.gov/17641028

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mapping the fodrin binding domain in CD45, a leukocyte membrane-associated tyrosine phosphatase

1 reference

https://pubmed.ncbi.nlm.nih.gov/17641028

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct roles for LFA-1 and CD28 during activation of naive T cells: adhesion versus costimulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17641028

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional consequences of costimulation by ICAM-1 on IL-2 gene expression and T cell activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17641028

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LFA-1 interaction with ICAM-1 and ICAM-2 regulates Th2 cytokine production

1 reference

https://pubmed.ncbi.nlm.nih.gov/17641028

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A receptor/cytoskeletal movement triggered by costimulation during T cell activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17641028

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TCR signaling induces selective exclusion of CD43 from the T cell-antigen-presenting cell contact site

1 reference

https://pubmed.ncbi.nlm.nih.gov/17641028

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The dependence for leukocyte function-associated antigen-1/ICAM-1 interactions in T cell activation cannot be overcome by expression of high density TCR ligand

1 reference

https://pubmed.ncbi.nlm.nih.gov/17641028

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defective CD8+ T cell activation and cytolytic function in the absence of LFA-1 cannot be restored by increased TCR signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/17641028

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of IL-4 responses after T cell priming in the context of LFA-1 costimulation is not reversed by restimulation in the presence of CD28 costimulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17641028

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-LFA-1 therapy induces long-term islet allograft acceptance in the absence of IFN-gamma or IL-4

1 reference

https://pubmed.ncbi.nlm.nih.gov/17641028

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intercellular adhesion molecule 1 is critical for activation of CD28-deficient T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17641028

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4049/JIMMUNOL.179.3.1616

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

22 August 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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