Population Pharmacokinetics of Methylphenidate in Healthy Adults Emphasizing Novel and Known Effects of Several Carboxylesterase 1 (CES1) Variants. (Q37700662)

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scientific article published on 18 October 2016

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English	Population Pharmacokinetics of Methylphenidate in Healthy Adults Emphasizing Novel and Known Effects of Several Carboxylesterase 1 (CES1) Variants.	scientific article published on 18 October 2016

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scholarly article

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25 March 2020

Population Pharmacokinetics of Methylphenidate in Healthy Adults Emphasizing Novel and Known Effects of Several Carboxylesterase 1 (CES1) Variants (English)

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25 March 2020

pharmacokinetics

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Yassine Kamal Lyauk

1

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25 March 2020

Troels K Bergmann

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25 March 2020

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25 March 2020

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25 March 2020

L Ferrero-Milliani

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D Bjerre

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25 March 2020

K P Dalhoff

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25 March 2020

H B Rasmussen

8

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G Jürgens

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18 October 2016

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25 March 2020

Clinical and Translational Science

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25 March 2020

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25 March 2020

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25 March 2020

337-345

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25 March 2020

Population pharmacokinetics of methylphenidate hydrochloride extended-release multiple-layer beads in pediatric subjects with attention deficit hyperactivity disorder

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Effect of carboxylesterase 1 c.428G > A single nucleotide variation on the pharmacokinetics of quinapril and enalapril

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Methylphenidate Efficacy: Immediate versus Extended Release at Short Term in Mexican Children with ADHD Assessed by Conners Scale and EEG.

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The functional G143E variant of carboxylesterase 1 is associated with increased clopidogrel active metabolite levels and greater clopidogrel response

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Performance of methods for handling missing categorical covariate data in population pharmacokinetic analyses

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A discriminative analytical method for detection of CES1A1 and CES1A2/CES1A3 genetic variants

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Two CES1 gene mutations lead to dysfunctional carboxylesterase 1 activity in man: clinical significance and molecular basis

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Methylphenidate is stereoselectively hydrolyzed by human carboxylesterase CES1A1.

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Comparative pharmacodynamics and plasma concentrations of d-threo-methylphenidate hydrochloride after single doses of d-threo-methylphenidate hydrochloride and d,l-threo-methylphenidate hydrochloride in a double-blind, placebo-controlled, crossover

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Population pharmacokinetics of methylphenidate in children with attention-deficit hyperactivity disorder

1 reference

https://pubmed.ncbi.nlm.nih.gov/27754602

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Population pharmacodynamic modeling of various extended-release formulations of methylphenidate in children with attention deficit hyperactivity disorder via meta-analysis

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12 December 2020

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10.1111/CTS.12423

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25 March 2020

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25 March 2020

PubMed publication ID

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25 March 2020

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