What determines Th2 differentiation, in vitro and in vivo? (Q37692831)

22 August 2017

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title

What determines Th2 differentiation, in vitro and in vivo? (English)

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22 August 2017

William E Paul

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22 August 2017

publication date

16 February 2010

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Immunology & Cell Biology

22 August 2017

published in

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22 August 2017

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22 August 2017

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22 August 2017

page(s)

236-239

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Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4-producing cells

22 August 2017

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Interleukin 2 plays a central role in Th2 differentiation.

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Independent roles for IL-2 and GATA-3 in stimulating naive CD4+ T cells to generate a Th2-inducing cytokine environment

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Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch

21 January 2018

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T cell factor 1 initiates the T helper type 2 fate by inducing the transcription factor GATA-3 and repressing interferon-gamma.

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T helper cell fate specified by kinase-mediated interaction of T-bet with GATA-3.

21 January 2018

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Down-regulation of Gfi-1 expression by TGF-beta is important for differentiation of Th17 and CD103+ inducible regulatory T cells.

21 January 2018

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In vivo studies fail to reveal a role for IL-4 or STAT6 signaling in Th2 lymphocyte differentiation

21 January 2018

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Conditional deletion of Gata3 shows its essential function in T(H)1-T(H)2 responses.

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Gastrointestinal nematode expulsion in IL-4 knockout mice is IL-13 dependent.

21 January 2018

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TSLP: an epithelial cell cytokine that regulates T cell differentiation by conditioning dendritic cell maturation

21 January 2018

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Spontaneous atopic dermatitis in mice expressing an inducible thymic stromal lymphopoietin transgene specifically in the skin

21 January 2018

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Maintenance and polarization of human TH2 central memory T cells by thymic stromal lymphopoietin-activated dendritic cells.

21 January 2018

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IL-25 augments type 2 immune responses by enhancing the expansion and functions of TSLP-DC-activated Th2 memory cells

21 January 2018

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A mechanism for the initiation of allergen-induced T helper type 2 responses

21 January 2018

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TSLP acts on infiltrating effector T cells to drive allergic skin inflammation

21 January 2018

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A LAT mutation that inhibits T cell development yet induces lymphoproliferation

21 January 2018

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Identifying the MAGUK protein Carma-1 as a central regulator of humoral immune responses and atopy by genome-wide mouse mutagenesis.

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Opposing functions of the T cell receptor kinase ZAP-70 in immunity and tolerance differentially titrate in response to nucleotide substitutions.

21 January 2018

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21 January 2018

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Omega-1, a glycoprotein secreted by Schistosoma mansoni eggs, drives Th2 responses

21 January 2018

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The major component in schistosome eggs responsible for conditioning dendritic cells for Th2 polarization is a T2 ribonuclease (omega-1)

21 January 2018

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Mouse splenic and bone marrow cell populations that express high-affinity Fc epsilon receptors and produce interleukin 4 are highly enriched in basophils

21 January 2018

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Basophils contribute to T(H)2-IgE responses in vivo via IL-4 production and presentation of peptide-MHC class II complexes to CD4+ T cells.

21 January 2018

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Basophils function as antigen-presenting cells for an allergen-induced T helper type 2 response

21 January 2018

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MHC class II-dependent basophil-CD4+ T cell interactions promote T(H)2 cytokine-dependent immunity.

21 January 2018

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IL-1 acts directly on CD4 T cells to enhance their antigen-driven expansion and differentiation

21 January 2018

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Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants

21 January 2018

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Cutting edge: inflammasome activation by alum and alum's adjuvant effect are mediated by NLRP3.

21 January 2018

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Stat5a regulates T helper cell differentiation by several distinct mechanisms

21 January 2018

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7 January 2021

Stat5 activation plays a critical role in Th2 differentiation

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https://api.crossref.org/works/10.1038%2FICB.2010.2

7 January 2021

Basophils can directly present or cross-present antigen to CD8 lymphocytes and alter CD8 T cell differentiation into IL-10-producing phenotypes

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https://api.crossref.org/works/10.1038%2FICB.2010.2

7 January 2021

Special regulatory T-cell review: FOXP3 biochemistry in regulatory T cells--how diverse signals regulate suppression

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7 January 2021

Identifiers

DOI

10.1038/ICB.2010.2

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22 August 2017

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