Pharmacokinetics of Standard- and Reduced-Dose Recombinant Human Soluble Thrombomodulin in Patients with Septic Disseminated Intravascular Coagulation during Continuous Hemodiafiltration (Q37653885)

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scientific article published on 21 February 2017

Language	Label	Description	Also known as
English	Pharmacokinetics of Standard- and Reduced-Dose Recombinant Human Soluble Thrombomodulin in Patients with Septic Disseminated Intravascular Coagulation during Continuous Hemodiafiltration	scientific article published on 21 February 2017

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Pharmacokinetics of Standard- and Reduced-Dose Recombinant Human Soluble Thrombomodulin in Patients with Septic Disseminated Intravascular Coagulation during Continuous Hemodiafiltration (English)

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

0 references

disseminated intravascular coagulation

0 references

hemodiafiltration

1 reference

based on heuristic

inferred from title

8

object named as

Shigeto Oda

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

author name string

Eizo Watanabe

1

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Shingo Yamazaki

2

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Daisuke Setoguchi

3

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Tomohito Sadahiro

4

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Yoshihisa Tateishi

5

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Tatsuya Suzuki

6

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Itsuko Ishii

7

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

publication date

21 February 2017

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

Frontiers in Medicine

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

4

1 reference

Europe PubMed Central

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21 August 2017

15

1 reference

Europe PubMed Central

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21 August 2017

Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5318446

23 August 2017

Antithrombin III in critically ill patients: systematic review with meta-analysis and trial sequential analysis

1 reference

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23 August 2017

Bench-to-bedside review: the role of activated protein C in maintaining endothelial tight junction function and its relationship to organ injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5318446

23 August 2017

A multicenter, prospective validation of disseminated intravascular coagulation diagnostic criteria for critically ill patients: comparing current criteria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5318446

23 August 2017

The N-terminal domain of thrombomodulin sequesters high-mobility group-B1 protein, a novel antiinflammatory mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5318446

23 August 2017

Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5318446

23 August 2017

Sepsis: a roadmap for future research

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5318446

6 September 2017

A randomized, double-blind, placebo-controlled, Phase 2b study to evaluate the safety and efficacy of recombinant human soluble thrombomodulin, ART-123, in patients with sepsis and suspected disseminated intravascular coagulation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5318446

6 September 2017

Current topics on cytokine removal technologies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5318446

14 September 2017

Population pharmacokinetic analysis of thrombomodulin alfa to support dosing rationale in patients with renal impairment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5318446

1 September 2018

Continuous hemodiafiltration with a cytokine-adsorbing hemofilter in patients with septic shock: a preliminary report

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5318446

1 September 2018

Sepsis-induced disseminated intravascular coagulation, symmetrical peripheral gangrene, and amputations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5318446

1 September 2018

Drotrecogin alfa (activated) in adults with septic shock.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5318446

1 September 2018

Model-based analysis of covariate effects on population pharmacokinetics of thrombomodulin alfa in patients with disseminated intravascular coagulation and normal subjects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5318446

1 September 2018

Efficacy and safety of tifacogin (recombinant tissue factor pathway inhibitor) in severe sepsis: a randomized controlled trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5318446

1 September 2018

Phase I study of a novel recombinant human soluble thrombomodulin, ART-123

1 reference

https://pubmed.ncbi.nlm.nih.gov/28271063

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Continuous hemodiafiltration with a cytokine-adsorbing hemofilter for sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/28271063

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacy and safety of recombinant human soluble thrombomodulin (ART-123) in disseminated intravascular coagulation: results of a phase III, randomized, double-blind clinical trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/28271063

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics and pharmacodynamics of recombinant soluble thrombomodulin in disseminated intravascular coagulation patients with renal impairment

1 reference

https://pubmed.ncbi.nlm.nih.gov/28271063

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute Renal Failure in Critically Ill Patients A Multinational, Multicenter Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/28271063

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics and safety of a novel recombinant soluble human thrombomodulin, ART-123, in healthy male volunteers

1 reference

https://pubmed.ncbi.nlm.nih.gov/28271063

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trial failure prompts soul-searching for critical-care specialists

1 reference

https://pubmed.ncbi.nlm.nih.gov/28271063

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3389/FMED.2017.00015

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

21 August 2017

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