Lambda integrase cleaves DNA in cis. (Q37636420)

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28 October 2019

title

Lambda integrase cleaves DNA in cis (English)

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28 October 2019

S E Nunes-Düby

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28 October 2019

R S Tirumalai

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28 October 2019

L Dorgai

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28 October 2019

E Yagil

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28 October 2019

R A Weisberg

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28 October 2019

A Landy

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28 October 2019

language of work or name

English

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publication date

1 September 1994

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28 October 2019

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28 October 2019

volume

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28 October 2019

issue

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28 October 2019

page(s)

4421-4430

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Substrate-assisted catalysis in the cleavage of DNA by the EcoRI and EcoRV restriction enzymes

28 October 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395369

Dissecting the resolution reaction of lambda integrase using suicide Holliday junction substrates

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395369

Rapid detection and isolation of covalent DNA/protein complexes: application to topoisomerase I and II.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395369

Holliday intermediates and reaction by-products in FLP protein-promoted site-specific recombination

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395369

The integrase family of site-specific recombinases: regional similarities and global diversity

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395369

Step-arrest mutants of FLP recombinase: implications for the catalytic mechanism of DNA recombination

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395369

Isolation and characterization of intermediates in site-specific recombination

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395369

Dynamic, structural, and regulatory aspects of lambda site-specific recombination

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395369

The FLP recombinase of the Saccharomyces cerevisiae 2 microns plasmid attaches covalently to DNA via a phosphotyrosyl linkage

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395369

Characterization of Holliday structures in FLP protein-promoted site-specific recombination

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395369

Specificity determinants in the attachment sites of bacteriophages HK022 and lambda

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395369

Functional analysis of box I mutations in yeast site-specific recombinases Flp and R: pairwise complementation with recombinase variants lacking the active-site tyrosine

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395369

Catalysis by site-specific recombinases

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395369

Nicking-closing activity associated with bacteriophage lambda int gene product

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395369

Mechanism of cleavage and ligation by FLP recombinase: classification of mutations in FLP protein by in vitro complementation analysis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395369

DNA splicing by an active site mutant of Flp recombinase. Possible catalytic cooperativity between the inactive protein and its DNA substrate.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395369

Tests for the fractional active-site model in Flp site-specific recombination. Assembly of a functional recombination complex in half-site and full-site strand transfer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395369

Concerted action of three distinct domains in the DNA cleaving-joining reaction catalyzed by relaxase (TraI) of conjugative plasmid RP4.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395369

Resolution of synthetic chi structures by the FLP site-specific recombinase

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395369

The mechanism of conservative site-specific recombination

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395369

Recombination at ColE1 cer requires the Escherichia coli xerC gene product, a member of the lambda integrase family of site-specific recombinases

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395369

Site-specific genetic recombination: hops, flips, and flops.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395369

Mechanistic and structural complexity in the site-specific recombination pathways of Int and FLP.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395369

Complementation of bacteriophage lambda integrase mutants: evidence for an intersubunit active site.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395369

Convergent evolution: the need to be explicit

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395369

Ligation of synthetic activated DNA substrates by site-specific recombinases and topoisomerase I.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395369

Resolution of synthetic att-site Holliday structures by the integrase protein of bacteriophage λ

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395369

Homology-dependent interactions in phage lambda site-specific recombination

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395369

Autonomous DNA binding domains of lambda integrase recognize two different sequence families

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395369

Identification of the active site tyrosine of Flp recombinase. Possible relevance of its location to the mechanism of recombination

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395369

Mapping of a higher order protein-DNA complex: two kinds of long-range interactions in lambda attL.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395369

Evidence for a second conserved arginine residue in the integrase family of recombination proteins

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395369

Lambda Int protein bridges between higher order complexes at two distant chromosomal loci attL and attR.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395369

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395369

Determinants of site-specific recombination in the lambdoid coliphage HK022. An evolutionary change in specificity

1 September 2018

1 reference

12 December 2020

Half-att site substrates reveal the homology independence and minimal protein requirements for productive synapsis in lambda excisive recombination

1 reference

12 December 2020

Interactions between lambda Int molecules bound to sites in the region of strand exchange are required for efficient Holliday junction resolution

1 reference

12 December 2020

Protein-based asymmetry and protein-protein interactions in FLP recombinase-mediated site-specific recombination

1 reference

12 December 2020

DNA cleavage in trans by the active site tyrosine during Flp recombination: Switching protein partners before exchanging strands

1 reference

12 December 2020

Mutagenesis of a conserved region of the gene encoding the FLP recombinase of Saccharomyces cerevisiae. A role for arginine 191 in binding and ligation

1 reference

12 December 2020

Half-site strand transfer by step-arrest mutants of yeast site-specific recombinase Flp

1 reference

12 December 2020

Ligation activity of FLP recombinase. The strand ligation activity of a site-specific recombinase using an activated DNA substrate

1 reference

12 December 2020

Sequence-specific cleavage of DNA via nucleophilic attack of hydrogen peroxide, assisted by Flp recombinase

1 reference

12 December 2020

Mechanism of site-specific recombination. Logic of assembling recombinase catalytic site from fractional active sites

1 reference

12 December 2020

Site-specific recombination intermediates trapped with suicide substrates

1 reference

12 December 2020

Suicide recombination substrates yield covalent lambda integrase-DNA complexes and lead to identification of the active site tyrosine

1 reference

12 December 2020

10.1002/J.1460-2075.1994.TB06762.X

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7925285%20AND%20SRC:MED&resulttype=core&format=json

28 October 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7925285%20AND%20SRC:MED&resulttype=core&format=json

28 October 2019

PubMed publication ID

7925285

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7925285%20AND%20SRC:MED&resulttype=core&format=json