Biophysical properties of the clinical-stage antibody landscape. (Q37626251)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28096333%20AND%20SRC:MED&resulttype=core&format=json

10 April 2020

title

Biophysical properties of the clinical-stage antibody landscape (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28096333%20AND%20SRC:MED&resulttype=core&format=json

10 April 2020

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28096333%20AND%20SRC:MED&resulttype=core&format=json

10 April 2020

Tingwan Sun

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28096333%20AND%20SRC:MED&resulttype=core&format=json

10 April 2020

Stéphanie Durand

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28096333%20AND%20SRC:MED&resulttype=core&format=json

10 April 2020

Amy Hall

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28096333%20AND%20SRC:MED&resulttype=core&format=json

10 April 2020

Nga Rewa Houston

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28096333%20AND%20SRC:MED&resulttype=core&format=json

10 April 2020

Juergen H Nett

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28096333%20AND%20SRC:MED&resulttype=core&format=json

10 April 2020

Beth Sharkey

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28096333%20AND%20SRC:MED&resulttype=core&format=json

10 April 2020

Beata Bobrowicz

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28096333%20AND%20SRC:MED&resulttype=core&format=json

10 April 2020

Isabelle Caffry

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28096333%20AND%20SRC:MED&resulttype=core&format=json

10 April 2020

Yao Yu

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28096333%20AND%20SRC:MED&resulttype=core&format=json

10 April 2020

Yuan Cao

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28096333%20AND%20SRC:MED&resulttype=core&format=json

10 April 2020

Heather Lynaugh

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28096333%20AND%20SRC:MED&resulttype=core&format=json

10 April 2020

Michael Brown

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28096333%20AND%20SRC:MED&resulttype=core&format=json

10 April 2020

Hemanta Baruah

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28096333%20AND%20SRC:MED&resulttype=core&format=json

10 April 2020

Laura T Gray

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28096333%20AND%20SRC:MED&resulttype=core&format=json

10 April 2020

Eric M Krauland

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28096333%20AND%20SRC:MED&resulttype=core&format=json

10 April 2020

Yingda Xu

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28096333%20AND%20SRC:MED&resulttype=core&format=json

10 April 2020

Maximiliano Vásquez

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28096333%20AND%20SRC:MED&resulttype=core&format=json

10 April 2020

K Dane Wittrup

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28096333%20AND%20SRC:MED&resulttype=core&format=json

10 April 2020

language of work or name

English

0 references

publication date

17 January 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28096333%20AND%20SRC:MED&resulttype=core&format=json

10 April 2020

number of pages

1 reference

Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28096333%20AND%20SRC:MED&resulttype=core&format=json

10 April 2020

volume

114

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28096333%20AND%20SRC:MED&resulttype=core&format=json

10 April 2020

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28096333%20AND%20SRC:MED&resulttype=core&format=json

10 April 2020

page(s)

944-949

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28096333%20AND%20SRC:MED&resulttype=core&format=json

An analysis of the attrition of drug candidates from four major pharmaceutical companies

10 April 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5293111

High throughput cross-interaction measures for human IgG1 antibodies correlate with clearance rates in mice

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5293111

Charge-mediated influence of the antibody variable domain on FcRn-dependent pharmacokinetics.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5293111

In silico selection of therapeutic antibodies for development: viscosity, clearance, and chemical stability

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5293111

Improving monoclonal antibody selection and engineering using measurements of colloidal protein interactions

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5293111

Addressing polyspecificity of antibodies selected from an in vitro yeast presentation system: a FACS-based, high-throughput selection and analytical tool

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5293111

Somatic hypermutation maintains antibody thermodynamic stability during affinity maturation

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5293111

High-throughput analysis of concentration-dependent antibody self-association.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5293111

Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5293111

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5293111

Secretion efficiency in Saccharomyces cerevisiae of bovine pancreatic trypsin inhibitor mutants lacking disulfide bonds is correlated with thermodynamic stability

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5293111

A novel screening method to assess developability of antibody-like molecules

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5293111

Developability assessment during the selection of novel therapeutic antibodies.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5293111

High-throughput screening for developability during early-stage antibody discovery using self-interaction nanoparticle spectroscopy

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5293111

Aggregation risk prediction for antibodies and its application to biotherapeutic development

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5293111

Target-independent variable region mediated effects on antibody clearance can be FcRn independent

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5293111

The interplay of non-specific binding, target-mediated clearance and FcRn interactions on the pharmacokinetics of humanized antibodies

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5293111

An alternative assay to hydrophobic interaction chromatography for high-throughput characterization of monoclonal antibodies

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5293111

High throughput detection of antibody self-interaction by bio-layer interferometry

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5293111

Solubility evaluation of murine hybridoma antibodies

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5293111

A strategy for risk mitigation of antibodies with fast clearance.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5293111

Rapid analysis of antibody self-association in complex mixtures using immunogold conjugates

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5293111

High-throughput assessment of thermal and colloidal stability parameters for monoclonal antibody formulations

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5293111

The influence of drug-like concepts on decision-making in medicinal chemistry

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5293111

Protein folding stability can determine the efficiency of escape from endoplasmic reticulum quality control

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5293111

Asymptotic Theory of Certain "Goodness of Fit" Criteria Based on Stochastic Processes

1 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1616408114

Half-life of polyreactive antibodies

21 January 2018

1 reference

12 December 2020

Developability index: a rapid in silico tool for the screening of antibody aggregation propensity

1 reference

12 December 2020

Plasmonic measurements of monoclonal antibody self-association using self-interaction nanoparticle spectroscopy

1 reference

12 December 2020

Fc domain mediated self-association of an IgG1 monoclonal antibody under a low ionic strength condition

1 reference

12 December 2020

Development of high concentration protein biopharmaceuticals: The use of platform approaches in formulation development

1 reference

12 December 2020

Cross-interaction chromatography: a rapid method to identify highly soluble monoclonal antibody candidates

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1616408114

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28096333%20AND%20SRC:MED&resulttype=core&format=json

10 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28096333%20AND%20SRC:MED&resulttype=core&format=json

10 April 2020

PubMed publication ID

28096333

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28096333%20AND%20SRC:MED&resulttype=core&format=json