The biological properties of E6 and E7 oncoproteins from human papillomaviruses. (Q37617163)

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10 February 2020

review article

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title

The biological properties of E6 and E7 oncoproteins from human papillomaviruses (English)

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10 February 2020

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10 February 2020

Raffaella Ghittoni

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10 February 2020

Rosita Accardi

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10 February 2020

Tarik Gheit

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10 February 2020

Bakary Sylla

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10 February 2020

Massimo Tommasino

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10 February 2020

publication date

17 October 2009

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10 February 2020

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10 February 2020

volume

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10 February 2020

issue

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10 February 2020

page(s)

1-13

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A review of the aetiology of squamous cell carcinoma of the conjunctiva

10 February 2020

cites work

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Viral oncoproteins discriminate between p53 and the p53 homolog p73.

21 January 2018

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Human papillomavirus type 16 E7 binds to the conserved carboxy-terminal region of the TATA box binding protein and this contributes to E7 transforming activity

21 January 2018

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Association of the human papillomavirus type 16 E7 protein with the S-phase-specific E2F-cyclin A complex

21 January 2018

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TLR9 expression and function is abolished by the cervical cancer-associated human papillomavirus type 16.

21 January 2018

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21 January 2018

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Inhibition of Bak-induced apoptosis by HPV-18 E6.

21 January 2018

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12 December 2020

Rapid clearance of human papillomavirus and implications for clinical focus on persistent infections

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12 December 2020

Direct activation of cyclin-dependent kinase 2 by human papillomavirus E7.

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12 December 2020

Transcriptional regulation by dimerization: two sides to an incestuous relationship

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12 December 2020

Human papillomavirus-16 E7 protein inhibits the DNA interaction of the TATA binding transcription factor

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12 December 2020

Human papillomavirus type 16 E6 promotes retinoblastoma protein phosphorylation and cell cycle progression.

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12 December 2020

E7 oncoprotein of novel human papillomavirus type 108 lacking the E6 gene induces dysplasia in organotypic keratinocyte cultures

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12 December 2020

Specific down-modulation of Notch1 signaling in cervical cancer cells is required for sustained HPV-E6/E7 expression and late steps of malignant transformation

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12 December 2020

Effect of oral contraceptives on risk of cervical cancer in women with human papillomavirus infection: the IARC multicentric case-control study

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12 December 2020

Analysis of the p53-mediated G1 growth arrest pathway in cells expressing the human papillomavirus type 16 E7 oncoprotein

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12 December 2020

Human Papillomavirus Types in Head and Neck Squamous Cell Carcinomas Worldwide: A Systematic Review

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12 December 2020

The role of TP53 in Cervical carcinogenesis.

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12 December 2020

Human papillomavirus type 16 E7 binds to E2F1 and activates E2F1-driven transcription in a retinoblastoma protein-independent manner

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12 December 2020

Human papillomavirus type 16 E7 impairs the activation of the interferon regulatory factor-1.

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12 December 2020

Role of Bak in UV-induced apoptosis in skin cancer and abrogation by HPV E6 proteins

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12 December 2020

Human papillomavirus type 16 E7 associates with a histone H1 kinase and with p107 through sequences necessary for transformation

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12 December 2020

HPV E7 contributes to the telomerase activity of immortalized and tumorigenic cells and augments E6-induced hTERT promoter function

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12 December 2020

The E2F transcriptional network: old acquaintances with new faces

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12 December 2020

Determination of the binding affinity of different human papillomavirus E7 proteins for the tumour suppressor pRb by a plate-binding assay

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12 December 2020

Inhibition of CDK activity and PCNA-dependent DNA replication by p21 is blocked by interaction with the HPV-16 E7 oncoprotein

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12 December 2020

Human papillomavirus type 16 E7 oncoprotein associates with the cullin 2 ubiquitin ligase complex, which contributes to degradation of the retinoblastoma tumor suppressor

1 reference

12 December 2020

Temporally distinct patterns of p53-dependent and p53-independent apoptosis during mouse lens development

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12 December 2020

The E6 oncoproteins from human betapapillomaviruses differentially activate telomerase through an E6AP-dependent mechanism and prolong the lifespan of primary keratinocytes

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12 December 2020

Clinician's guide to human papillomavirus immunology: knowns and unknowns

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12 December 2020

Na+/H+ exchanger-dependent intracellular alkalinization is an early event in malignant transformation and plays an essential role in the development of subsequent transformation-associated phenotypes.

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12 December 2020

Inactivation of the cdk inhibitor p27KIP1 by the human papillomavirus type 16 E7 oncoprotein

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12 December 2020

Analysis of the interaction between human papillomavirus type 16 E7 and the TATA-binding protein, TBP

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12 December 2020

Systematic review of genomic integration sites of human papillomavirus genomes in epithelial dysplasia and invasive cancer of the female lower genital tract

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12 December 2020

p53, p63 and p73--solos, alliances and feuds among family members

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12 December 2020

Effects of human papillomavirus type 16 oncoproteins on survivin gene expression.

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12 December 2020

Prevalence and associated factors of betapapillomavirus infections in individuals without cutaneous squamous cell carcinoma

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12 December 2020

Bcl-2 family members and disease

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12 December 2020

Risk factors for progression of cervical intraepithelial neoplasm grade III to invasive cervical cancer.

1 reference

12 December 2020

Altered expression of TAP-1 and major histocompatibility complex class I in laryngeal papillomatosis: correlation of TAP-1 with disease.

1 reference

12 December 2020

The E6 protein of human papillomavirus type 16 binds to and inhibits co-activation by CBP and p300.

1 reference

12 December 2020

The E6 protein of the cutaneous human papillomavirus type 8 can stimulate the viral early and late promoters by distinct mechanisms

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12 December 2020

Induction of apoptosis in human papillomaviruspositive cancer cells by peptide aptamers targeting the viral E6 oncoprotein

1 reference

12 December 2020

The epidemiology of UV induced skin cancer

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12 December 2020

Efficiency of binding the retinoblastoma protein correlates with the transforming capacity of the E7 oncoproteins of the human papillomaviruses

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12 December 2020

Senescence and immortalization: role of telomeres and telomerase

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12 December 2020

E7 protein of human papilloma virus-16 induces degradation of retinoblastoma protein through the ubiquitin-proteasome pathway.

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12 December 2020

HPV16 E7 protein associates with the protein kinase p33CDK2 and cyclin A

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12 December 2020

Human papillomavirus 16 E6 oncoprotein binds to interferon regulatory factor-3 and inhibits its transcriptional activity

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12 December 2020

Single amino acid substitutions in "low-risk" human papillomavirus (HPV) type 6 E7 protein enhance features characteristic of the "high-risk" HPV E7 oncoproteins

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12 December 2020

Human papillomavirus type 32 does not display in vitro transforming properties.

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12 December 2020

Differential effect of tumor necrosis factor on proliferation of primary human keratinocytes and cell lines containing human papillomavirus types 16 and 18

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12 December 2020

The human papillomavirus type 16 E7 gene product interacts with and trans-activates the AP1 family of transcription factors

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12 December 2020

Binding of human papillomavirus type 16 E6 to E6AP is not required for activation of hTERT

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12 December 2020

MHC class I expression in HPV 16 positive cervical carcinomas is post-transcriptionally controlled and independent from c-myc overexpression

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12 December 2020

Regulation of Notch1 gene expression by p53 in epithelial cells

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12 December 2020

Human papillomavirus type 16 E6 and E7 oncoproteins upregulate c-IAP2 gene expression and confer resistance to apoptosis

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12 December 2020

Inactivation of the CYLD deubiquitinase by HPV E6 mediates hypoxia-induced NF-kappaB activation

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12 December 2020

Stimulation of human epidermal differentiation by delta-notch signalling at the boundaries of stem-cell clusters.

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12 December 2020

Membrane-associated guanylate kinases regulate adhesion and plasticity at cell junctions

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12 December 2020

Nonmelanoma cancers of the skin

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12 December 2020

Human papillomavirus type 16 E6 activates NF-kappaB, induces cIAP-2 expression, and protects against apoptosis in a PDZ binding motif-dependent manner

1 reference

12 December 2020

Epidemiologic classification of human papillomavirus types associated with cervical cancer

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12 December 2020

Classification of papillomaviruses

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12 December 2020

Oncogenic human papillomavirus E6 proteins target the discs large tumour suppressor for proteasome-mediated degradation

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12 December 2020

Molecular approaches to cervical cancer therapy

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12 December 2020

Identification of a novel telomerase repressor that interacts with the human papillomavirus type-16 E6/E6-AP complex

1 reference

12 December 2020

Degradation of the retinoblastoma tumor suppressor by the human papillomavirus type 16 E7 oncoprotein is important for functional inactivation and is separable from proteasomal degradation of E7.

1 reference

12 December 2020

The human papillomavirus E7 oncoprotein can uncouple cellular differentiation and proliferation in human keratinocytes by abrogating p21Cip1-mediated inhibition of cdk2.

1 reference

12 December 2020

The E6AP ubiquitin ligase is required for transactivation of the hTERT promoter by the human papillomavirus E6 oncoprotein.

1 reference

12 December 2020

Telomerase activation by the E6 gene product of human papillomavirus type 16.

1 reference

12 December 2020

Human papillomavirus (HPV) types 101 and 103 isolated from cervicovaginal cells lack an E6 open reading frame (ORF) and are related to gamma-papillomaviruses

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12 December 2020

Human papillomavirus type distribution in invasive cervical cancer and high-grade cervical lesions: a meta-analysis update.

1 reference

12 December 2020

Inactivation of interferon regulatory factor-1 tumor suppressor protein by HPV E7 oncoprotein. Implication for the E7-mediated immune evasion mechanism in cervical carcinogenesis

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12 December 2020

The human papillomavirus E6 protein and its contribution to malignant progression

1 reference

12 December 2020

Functional inactivation of p73, a homolog of p53 tumor suppressor protein, by human papillomavirus E6 proteins

1 reference

12 December 2020

The PDZ ligand domain of the human papillomavirus type 16 E6 protein is required for E6's induction of epithelial hyperplasia in vivo

1 reference

12 December 2020

Silencing of E7 oncogene restores functional E-cadherin expression in human papillomavirus 16-transformed keratinocytes

1 reference

12 December 2020

Pocket proteins and cell cycle control

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12 December 2020

A cellular protein mediates association of p53 with the E6 oncoprotein of human papillomavirus types 16 or 18

1 reference

12 December 2020

The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

1 reference

12 December 2020

Complex formation of human papillomavirus E7 proteins with the retinoblastoma tumor suppressor gene product

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12 December 2020

The interaction between human papillomavirus type 16 and FADD is mediated by a novel E6 binding domain.

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12 December 2020

Papillomaviruses and cancer: from basic studies to clinical application

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12 December 2020

E-cadherin-dependent adhesion of dendritic and Langerhans cells to keratinocytes is defective in cervical human papillomavirus-associated (pre)neoplastic lesions

1 reference

12 December 2020

Human papillomavirus E6 and E7: proteins which deregulate the cell cycle

1 reference

12 December 2020

The human papillomavirus E7 oncoprotein

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12 December 2020

Inhibition of p53 DNA binding by human papillomavirus E6 proteins

1 reference

12 December 2020

Biochemical epidemiology of cervical neoplasia: measuring cigarette smoke constituents in the cervix

1 reference

12 December 2020

HPV E6 degradation of p53 and PDZ containing substrates in an E6AP null background

1 reference

12 December 2020

Epidermodysplasia verruciformis human papillomavirus types and carcinoma of the conjunctiva: a pilot study

1 reference

12 December 2020

Chapter 8: Human papillomavirus and skin cancer.

1 reference

12 December 2020

Differential disruption of genomic integrity and cell cycle regulation in normal human fibroblasts by the HPV oncoproteins.

1 reference

12 December 2020

Comparison of the properties of the E6 and E7 genes of low- and high-risk cutaneous papillomaviruses reveals strongly transforming and high Rb-binding activity for the E7 protein of the low-risk human papillomavirus type 1.

1 reference

12 December 2020

Activity of the human papillomavirus E6 PDZ-binding motif correlates with an enhanced morphological transformation of immortalized human keratinocytes.

1 reference

12 December 2020

The antigen-presenting environment in normal and human papillomavirus (HPV)-related premalignant cervical epithelium

1 reference

12 December 2020

Comparative analysis of 19 genital human papillomavirus types with regard to p53 degradation, immortalization, phylogeny, and epidemiologic risk classification

1 reference

12 December 2020

Functional studies of E7 proteins from different HPV types

1 reference

12 December 2020

The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

1 reference

12 December 2020

Biological activities and molecular targets of the human papillomavirus E7 oncoprotein

1 reference

12 December 2020

Structure and transcription of human papillomavirus sequences in cervical carcinoma cells

1 reference

12 December 2020

Identification of a novel activity of human papillomavirus type 16 E6 protein in deregulating the G1/S transition

1 reference

12 December 2020

Sunlight and skin cancer: inhibition of p53 mutations in UV-irradiated mouse skin by sunscreens

1 reference

12 December 2020

Human papillomavirus E6 and Myc proteins associate in vivo and bind to and cooperatively activate the telomerase reverse transcriptase promoter

1 reference

12 December 2020

Papillomavirus E6 proteins

1 reference

12 December 2020

Role of parity and human papillomavirus in cervical cancer: the IARC multicentric case-control study.

1 reference

12 December 2020

Induction of pRb degradation by the human papillomavirus type 16 E7 protein is essential to efficiently overcome p16INK4a-imposed G1 cell cycle Arrest

1 reference

12 December 2020

Natural history of cervical intraepithelial neoplasia: a critical review.

1 reference

12 December 2020

Human papillomavirus E7 requires the protease calpain to degrade the retinoblastoma protein

1 reference

12 December 2020

Interaction of human papillomavirus type 11 E7 protein with TAP-1 results in the reduction of ATP-dependent peptide transport

1 reference

12 December 2020

The ubiquitin-specific peptidase USP15 regulates human papillomavirus type 16 E6 protein stability

1 reference

12 December 2020