Molecular Interactions between HIV-1 integrase and the two viral DNA ends within the synaptic complex that mediates concerted integration (Q37468745)

20 August 2017

Molecular Interactions between HIV-1 integrase and the two viral DNA ends within the synaptic complex that mediates concerted integration (English)

1 reference

20 August 2017

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molecular interaction

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Sibes Bera

1 reference

20 August 2017

Krishan K Pandey

series ordinal

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20 August 2017

Ajaykumar C Vora

series ordinal

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20 August 2017

Duane P Grandgenett

series ordinal

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20 August 2017

language of work or name

English

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publication date

9 April 2009

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Journal of Molecular Biology

20 August 2017

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20 August 2017

389

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20 August 2017

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20 August 2017

183-198

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describes a project that uses

20 August 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2791363/fullTextXML

inferred from PubMed Central ID database lookup

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Modeling, analysis, and validation of a novel HIV integrase structure provide insights into the binding modes of potent integrase inhibitors

23 August 2017

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Subunit-specific protein footprinting reveals significant structural rearrangements and a role for N-terminal Lys-14 of HIV-1 Integrase during viral DNA binding

23 August 2017

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Inhibition of human immunodeficiency virus type 1 concerted integration by strand transfer inhibitors which recognize a transient structural intermediate

23 August 2017

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Transcriptional coactivator LEDGF/p75 modulates human immunodeficiency virus type 1 integrase-mediated concerted integration

23 August 2017

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Distance determination in protein-DNA complexes using fluorescence resonance energy transfer

23 August 2017

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Retroviral DNA integration: reaction pathway and critical intermediates

23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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A naphthyridine carboxamide provides evidence for discordant resistance between mechanistically identical inhibitors of HIV-1 integrase

23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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Structure of a two-domain fragment of HIV-1 integrase: implications for domain organization in the intact protein

23 August 2017

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23 August 2017

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23 August 2017

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HIV-1 integrase inhibitors that compete with the target DNA substrate define a unique strand transfer conformation for integrase

23 August 2017

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Fluorescence resonance energy transfer as a structural tool for nucleic acids

23 August 2017

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Inhibitors of strand transfer that prevent integration and inhibit HIV-1 replication in cells

23 August 2017

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23 August 2017

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Sequence specificity of viral end DNA binding by HIV-1 integrase reveals critical regions for protein-DNA interaction

23 August 2017

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Footprints on the viral DNA ends in moloney murine leukemia virus preintegration complexes reflect a specific association with integrase

23 August 2017

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23 August 2017

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Folding of the multidomain human immunodeficiency virus type-I integrase

23 August 2017

1 reference

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Crystal structure of the catalytic domain of HIV-1 integrase: similarity to other polynucleotidyl transferases

23 August 2017

1 reference

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23 August 2017

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Synaptic complex formation of two retrovirus DNA attachment sites by integrase: a fluorescence energy transfer study

23 August 2017

1 reference

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23 August 2017

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23 August 2017

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Efficient concerted integration by recombinant human immunodeficiency virus type 1 integrase without cellular or viral cofactors

6 September 2017

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Structure-based mutagenesis of the human immunodeficiency virus type 1 DNA attachment site: effects on integration and cDNA synthesis.

14 September 2017

1 reference

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Specific and independent recognition of U3 and U5 att sites by human immunodeficiency virus type 1 integrase in vivo.

14 September 2017

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14 September 2017

1 reference

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Defining the DNA substrate binding sites on HIV-1 integrase

14 September 2017

1 reference

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Recombinant human immunodeficiency virus type 1 integrase exhibits a capacity for full-site integration in vitro that is comparable to that of purified preintegration complexes from virus-infected cells

26 June 2018

1 reference

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The terminal (catalytic) adenosine of the HIV LTR controls the kinetics of binding and dissociation of HIV integrase strand transfer inhibitors

26 June 2018

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A three-dimensional model of the human immunodeficiency virus type 1 integration complex

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791363

Processing of viral DNA ends channels the HIV-1 integration reaction to concerted integration.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791363

Modeling HIV-1 integrase complexes based on their hydrodynamic properties

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791363

Functional oligomeric state of avian sarcoma virus integrase

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791363

Structural determinants for HIV-1 integrase inhibition by beta-diketo acids

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791363

Multiple integrase functions are required to form the native structure of the human immunodeficiency virus type I intasome

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791363

Photo-cross-linking studies suggest a model for the architecture of an active human immunodeficiency virus type 1 integrase-DNA complex

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791363

Disruption of the terminal base pairs of retroviral DNA during integration

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791363

Rhodamine-based compounds as fluorogenic substrates for serine proteinases

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791363

Location of cyanine-3 on double-stranded DNA: importance for fluorescence resonance energy transfer studies

2 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19362096

12 December 2020

inferred from PubMed ID database lookup

Model of full-length HIV-1 integrase complexed with viral DNA as template for anti-HIV drug design.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19362096

12 December 2020

inferred from PubMed ID database lookup

The structure of cyanine 5 terminally attached to double-stranded DNA: implications for FRET studies

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19362096

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1016/J.JMB.2009.04.007

1 reference

20 August 2017

1 reference

20 August 2017

PubMed publication ID

19362096

1 reference