Post-translational modifications of Runx1 regulate its activity in the cell (Q37455493)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19386523%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

review article

1 reference

title

Post-translational modifications of Runx1 regulate its activity in the cell (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19386523%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19386523%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Lan Wang

1 reference

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26 January 2020

Gang Huang

1 reference

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26 January 2020

Xinyang Zhao

1 reference

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26 January 2020

Megan A Hatlen

1 reference

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26 January 2020

Fan Liu

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19386523%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Stephen D Nimer

1 reference

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26 January 2020

language of work or name

1 reference

21 April 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19386523%20AND%20SRC:MED&resulttype=core&format=json

Blood Cells, Molecules and Diseases

26 January 2020

published in

1 reference

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26 January 2020

volume

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26 January 2020

issue

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26 January 2020

page(s)

30-34

1 reference

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PRMT5-mediated methylation of histone H4R3 recruits DNMT3A, coupling histone and DNA methylation in gene silencing.

26 January 2020

cites work

1 reference

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The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation

23 August 2017

1 reference

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PEBP2-beta/CBF-beta-dependent phosphorylation of RUNX1 and p300 by HIPK2: implications for leukemogenesis

23 August 2017

1 reference

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Methylation of RUNX1 by PRMT1 abrogates SIN3A binding and potentiates its transcriptional activity

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743917

Chromatin regulation by AML1 complex

23 August 2017

1 reference

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Cyclin-dependent kinase phosphorylation of RUNX1/AML1 on 3 sites increases transactivation potency and stimulates cell proliferation

23 August 2017

1 reference

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Epigenetic silencing of the myelopoiesis regulator microRNA-223 by the AML1/ETO oncoprotein.

23 August 2017

1 reference

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MOZ and MORF, two large MYSTic HATs in normal and cancer stem cells

23 August 2017

1 reference

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Cdk6 blocks myeloid differentiation by interfering with Runx1 DNA binding and Runx1-C/EBPalpha interaction

23 August 2017

1 reference

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AML1/RUNX1 phosphorylation by cyclin-dependent kinases regulates the degradation of AML1/RUNX1 by the anaphase-promoting complex

23 August 2017

1 reference

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Roles of HIPK1 and HIPK2 in AML1- and p300-dependent transcription, hematopoiesis and blood vessel formation

23 August 2017

1 reference

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MOZ fusion proteins in acute myeloid leukaemia

23 August 2017

1 reference

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The hematopoietic transcription factor AML1 (RUNX1) is negatively regulated by the cell cycle protein cyclin D3.

23 August 2017

1 reference

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AML1-ETO fusion protein up-regulates TRKA mRNA expression in human CD34+ cells, allowing nerve growth factor-induced expansion

23 August 2017

1 reference

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Ordered cooperative functions of PRMT1, p300, and CARM1 in transcriptional activation by p53

23 August 2017

1 reference

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23 August 2017

ETO interacting proteins

1 reference

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Effects of the leukemia-associated AML1-ETO protein on hematopoietic stem and progenitor cells

23 August 2017

1 reference

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AML-1 is required for megakaryocytic maturation and lymphocytic differentiation, but not for maintenance of hematopoietic stem cells in adult hematopoiesis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743917

FoxO3a regulates erythroid differentiation and induces BTG1, an activator of protein arginine methyl transferase 1

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743917

The corepressor mSin3A regulates phosphorylation-induced activation, intranuclear location, and stability of AML1.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743917

Histone lysine methylation: a signature for chromatin function

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743917

SUV39H1 interacts with AML1 and abrogates AML1 transactivity. AML1 is methylated in vivo

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743917

MDM2-HDAC1-mediated deacetylation of p53 is required for its degradation

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743917

Distinct roles for CREB-binding protein and p300 in hematopoietic stem cell self-renewal

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743917

Activation of AML1-mediated transcription by MOZ and inhibition by the MOZ-CBP fusion protein

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743917

ETO, a target of t(8;21) in acute leukemia, makes distinct contacts with multiple histone deacetylases and binds mSin3A through its oligomerization domain

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743917

Arginine N-methyltransferase 1 is required for early postimplantation mouse development, but cells deficient in the enzyme are viable

23 August 2017

1 reference

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Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP

23 August 2017

1 reference

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CREB-binding protein and p300: molecular integrators of hematopoietic transcription.

23 August 2017

1 reference

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A mechanism of repression by acute myeloid leukemia-1, the target of multiple chromosomal translocations in acute leukemia

23 August 2017

1 reference

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ETO, a target of t(8;21) in acute leukemia, interacts with the N-CoR and mSin3 corepressors

23 August 2017

1 reference

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Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

23 August 2017

1 reference

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Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases

23 August 2017

1 reference

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Interaction and functional cooperation of the leukemia-associated factors AML1 and p300 in myeloid cell differentiation

23 August 2017

1 reference

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Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300

23 August 2017

1 reference

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The AML1/ETO fusion protein activates transcription of BCL-2

23 August 2017

1 reference

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The extracellular signal-regulated kinase pathway phosphorylates AML1, an acute myeloid leukemia gene product, and potentially regulates its transactivation ability

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743917

CpG-rich islands and the function of DNA methylation

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743917

Inhibition of the transforming growth factor beta 1 signaling pathway by the AML1/ETO leukemia-associated fusion protein

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743917

Selective anti-leukaemic activity of low-dose histone deacetylase inhibitor ITF2357 on AML1/ETO-positive cells

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743917

Novel role of HDAC inhibitors in AML1/ETO AML cells: activation of apoptosis and phagocytosis through induction of annexin A1.

14 September 2017

1 reference

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Targeting AML1/ETO-histone deacetylase repressor complex: a novel mechanism for valproic acid-mediated gene expression and cellular differentiation in AML1/ETO-positive acute myeloid leukemia cells

14 September 2017

1 reference

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Histone deacetylase inhibitors induce the degradation of the t(8;21) fusion oncoprotein

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743917

Thrombopoietin regulates IEX-1 gene expression through ERK-induced AML1 phosphorylation.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743917

Interplay of RUNX1/MTG8 and DNA methyltransferase 1 in acute myeloid leukemia.

14 September 2017

1 reference

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Physical and functional link of the leukemia-associated factors AML1 and PML.

14 September 2017

1 reference

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Histone deacetylase inhibition improves dendritic cell differentiation of leukemic blasts with AML1-containing fusion proteins

14 September 2017

1 reference

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AML1 is functionally regulated through p300-mediated acetylation on specific lysine residues.

14 September 2017

1 reference

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AML1/RUNX1 increases during G1 to S cell cycle progression independent of cytokine-dependent phosphorylation and induces cyclin D3 gene expression

14 September 2017

1 reference

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The AML1-ETO fusion protein promotes the expansion of human hematopoietic stem cells

14 September 2017

1 reference

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The AML1/ETO fusion protein blocks transactivation of the GM-CSF promoter by AML1B.

28 September 2017

1 reference

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RNA and protein interactions modulated by protein arginine methylation.

28 September 2017

1 reference

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AML1A and AML1B can transactivate the human IL-3 promoter.

26 June 2018

1 reference

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Arginine methylation of FOXO transcription factors inhibits their phosphorylation by Akt.

26 June 2018

1 reference

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Reversal of p15/INK4b hypermethylation in AML1/ETO-positive and -negative myeloid leukemia cell lines.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743917

Mice homozygous for a truncated form of CREB-binding protein exhibit defects in hematopoiesis and vasculo-angiogenesis.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743917

The t(8;21) fusion protein, AML1/ETO, transforms NIH3T3 cells and activates AP-1.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743917

PU.1 is a major downstream target of AML1 (RUNX1) in adult mouse hematopoiesis

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2743917

A transcription-factor-binding surface of coactivator p300 is required for haematopoiesis

3 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19386523

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.BCMD.2009.03.005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19386523%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19386523%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

PubMed publication ID

19386523

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19386523%20AND%20SRC:MED&resulttype=core&format=json