Silymarin attenuates cigarette smoke extract-induced inflammation via simultaneous inhibition of autophagy and ERK/p38 MAPK pathway in human bronchial epithelial cells (Q37428190)

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English	Silymarin attenuates cigarette smoke extract-induced inflammation via simultaneous inhibition of autophagy and ERK/p38 MAPK pathway in human bronchial epithelial cells	scientific article

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scholarly article

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Europe PubMed Central

PMC publication ID

20 August 2017

Silymarin attenuates cigarette smoke extract-induced inflammation via simultaneous inhibition of autophagy and ERK/p38 MAPK pathway in human bronchial epithelial cells (English)

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Europe PubMed Central

PMC publication ID

20 August 2017

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Diandian Li

1

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20 August 2017

Jun Hu

2

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20 August 2017

Tao Wang

3

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20 August 2017

Xue Zhang

4

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20 August 2017

Lian Liu

5

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20 August 2017

Hao Wang

6

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20 August 2017

Yanqiu Wu

7

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20 August 2017

Dan Xu

8

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20 August 2017

Fuqiang Wen

9

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20 August 2017

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publication date

22 November 2016

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20 August 2017

Scientific Reports

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20 August 2017

6

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20 August 2017

37751

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Europe PubMed Central

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20 August 2017

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Creative Commons Attribution 4.0 International

22 November 2016

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April 2022 Public Data File from Crossref

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14,15-Epoxyeicosatrienoic acid suppresses cigarette smoke condensate-induced inflammation in lung epithelial cells by inhibiting autophagy

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Association of autophagy related gene polymorphisms with neutrophilic airway inflammation in adult asthma

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TLR4 deficiency promotes autophagy during cigarette smoke-induced pulmonary emphysema

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Autophagy in immunity and inflammation

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Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

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Autophagy and the Integrated Stress Response

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Autophagy protein microtubule-associated protein 1 light chain-3B (LC3B) activates extrinsic apoptosis during cigarette smoke-induced emphysema

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Endogenous HMGB1 regulates autophagy

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Cigarette smoke-induced autophagy is regulated by SIRT1-PARP-1-dependent mechanism: implication in pathogenesis of COPD.

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Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production

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Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease

1 reference

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Multifaceted mechanisms in COPD: inflammation, immunity, and tissue repair and destruction.

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Pulmonary epithelium, cigarette smoke, and chronic obstructive pulmonary disease

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Autophagosome formation: core machinery and adaptations

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Identification of multiple MAPK-mediated transcription factors regulated by tobacco smoke in airway epithelial cells

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MAP kinases and cell migration

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LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

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WNT/β-catenin signaling regulates cigarette smoke-induced airway inflammation via the PPARδ/p38 pathway

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Autophagy proteins regulate ERK phosphorylation

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Pim1 kinase protects airway epithelial cells from cigarette smoke-induced damage and airway inflammation.

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Insufficient autophagy promotes bronchial epithelial cell senescence in chronic obstructive pulmonary disease

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Autophagy links inflammasomes to atherosclerotic progression.

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26 June 2018

A non-canonical MEK/ERK signaling pathway regulates autophagy via regulating Beclin 1.

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26 June 2018

Silymarin attenuates airway inflammation induced by cigarette smoke in mice

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5118787

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Increased phosphorylated p38 mitogen-activated protein kinase in COPD lungs.

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Silibinin attenuates allergic airway inflammation in mice

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Silymarin, the antioxidant component of Silybum marianum, prevents sepsis-induced acute lung and brain injury

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Silymarin protects against acute ethanol-induced hepatotoxicity in mice

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2 September 2018

Increased activation of p38 MAPK in COPD

1 reference

https://api.crossref.org/works/10.1038%2FSREP37751

21 January 2018

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10.1038/SREP37751

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Europe PubMed Central

PMC publication ID

20 August 2017

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PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

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