Anti-CCR7 therapy exerts a potent anti-tumor activity in a xenograft model of human mantle cell lymphoma (Q37427684)

20 August 2017

Anti-CCR7 therapy exerts a potent anti-tumor activity in a xenograft model of human mantle cell lymphoma (English)

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20 August 2017

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10 June 2020

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10 June 2020

author name string

Beatriz Somovilla-Crespo

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10 June 2020

Manuel Alfonso-Pérez

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10 June 2020

Carlos Cuesta-Mateos

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10 June 2020

Cristina Carballo-de Dios

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10 June 2020

Amada E Beltrán

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10 June 2020

Fernando Terrón

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10 June 2020

Juan J Pérez-Villar

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10 June 2020

Carlos Gamallo-Amat

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10 June 2020

Elena Fernández-Ruiz

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10 June 2020

Cecilia Muñoz-Calleja

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10 June 2020

publication date

4 December 2013

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Journal of Hematology & Oncology

20 August 2017

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10 June 2020

volume

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10 June 2020

page(s)

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Targeting chronic lymphocytic leukemia cells with a humanized monoclonal antibody specific for CD44.

10 June 2020

cites work

1 reference

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Combination of rituximab, bendamustine, and cytarabine for patients with mantle-cell non-Hodgkin lymphoma ineligible for intensive regimens or autologous transplantation

23 August 2017

1 reference

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Coming full circle: 70 years of chronic lymphocytic leukemia cell redistribution, from glucocorticoids to inhibitors of B-cell receptor signaling

23 August 2017

1 reference

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Mechanisms of action of CD20 antibodies

23 August 2017

1 reference

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Molecular pathogenesis of mantle cell lymphoma

23 August 2017

1 reference

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Homeostatic chemokines guide lymphoma cells to tumor growth-promoting niches within secondary lymphoid organs

23 August 2017

1 reference

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Lymph node homing of T cells and dendritic cells via afferent lymphatics

23 August 2017

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CCL21/CCR7 prevents apoptosis via the ERK pathway in human non-small cell lung cancer cells

23 August 2017

1 reference

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Novel targeted therapies for mantle cell lymphoma

23 August 2017

1 reference

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Chemokine-dependent B cell-T cell interactions in chronic lymphocytic leukemia and multiple myeloma - targets for therapeutic intervention?

23 August 2017

1 reference

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The clinically active BTK inhibitor PCI-32765 targets B-cell receptor- and chemokine-controlled adhesion and migration in chronic lymphocytic leukemia

23 August 2017

1 reference

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Targeting CXCR4 with cell-penetrating pepducins in lymphoma and lymphocytic leukemia

23 August 2017

1 reference

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Lymph node B lymphocyte trafficking is constrained by anatomy and highly dependent upon chemoattractant desensitization.

23 August 2017

1 reference

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The chemokine system and cancer.

23 August 2017

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Homeostatic chemokine receptors and organ-specific metastasis

23 August 2017

1 reference

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Effect of Chemokine Receptors CCR7 on Disseminated Behavior of Human T cell Lymphoma: clinical and experimental study

23 August 2017

1 reference

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Molecular Pathogenesis of Hodgkin's Lymphoma: Increasing Evidence of the Importance of the Microenvironment

23 August 2017

1 reference

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Mantle cell lymphoma: biology, pathogenesis, and the molecular basis of treatment in the genomic era

23 August 2017

1 reference

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The microenvironment in mature B-cell malignancies: a target for new treatment strategies

23 August 2017

1 reference

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CCR7 signalling as an essential regulator of CNS infiltration in T-cell leukaemia

23 August 2017

1 reference

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Improvement of Overall Survival in Advanced Stage Mantle Cell Lymphoma

23 August 2017

1 reference

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Orchestrating the orchestrators: chemokines in control of T cell traffic

23 August 2017

1 reference

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CCR7 and its ligands: balancing immunity and tolerance

23 August 2017

1 reference

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Getting to the site of inflammation: the leukocyte adhesion cascade updated

23 August 2017

1 reference

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Lymphoma dissemination: the other face of lymphocyte homing

23 August 2017

1 reference

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Immunochemotherapy with rituximab and overall survival in patients with indolent or mantle cell lymphoma: a systematic review and meta-analysis

23 August 2017

1 reference

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Chemokine receptors that mediate B cell homing to secondary lymphoid tissues are highly expressed in B cell chronic lymphocytic leukemia and non-Hodgkin lymphomas with widespread nodular dissemination

23 August 2017

1 reference

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Homing and cellular traffic in lymph nodes

23 August 2017

1 reference

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The chemokine receptor CCR7 and alpha4 integrin are important for migration of chronic lymphocytic leukemia cells into lymph nodes

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879031

CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879031

Enhancement of the anti-tumor activity of therapeutic monoclonal antibodies by CXCR4 antagonists

23 August 2017

1 reference

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CCR7 Mediates Directed Growth of Melanomas Towards Lymphatics

6 September 2017

1 reference

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Anti-CCR7 monoclonal antibodies as a novel tool for the treatment of chronic lymphocyte leukemia.

14 September 2017

1 reference

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Chemokine receptor 7 activates phosphoinositide-3 kinase-mediated invasive and prosurvival pathways in head and neck cancer cells independent of EGFR.

14 September 2017

1 reference

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Manifestation of spontaneous and early autoimmune gastritis in CCR7-deficient mice

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879031

Cooperative function of CCR7 and lymphotoxin in the formation of a lymphoma-permissive niche within murine secondary lymphoid organs

26 June 2018

1 reference

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Analysis of migratory and prosurvival pathways induced by the homeostatic chemokines CCL19 and CCL21 in B-cell chronic lymphocytic leukemia.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879031

Spleen tyrosine kinase inhibition prevents chemokine- and integrin-mediated stromal protective effects in chronic lymphocytic leukemia

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879031

Investigation of the mechanism of action of alemtuzumab in a human CD52 transgenic mouse model.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879031

Intensive treatment strategies may not provide superior outcomes in mantle cell lymphoma: overall survival exceeding 7 years with standard therapies

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879031

Homeostatic chemokines drive migration of malignant B cells in patients with non-Hodgkin lymphomas

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3879031

Phospho-proteomic analysis of mantle cell lymphoma cells suggests a pro-survival role of B-cell receptor signaling

2 September 2018

1 reference

12 December 2020

Chemokines in health and disease

1 reference

12 December 2020

Expression of the chemokine receptors CXCR4, CXCR5, and CCR7 in primary central nervous system lymphoma

1 reference

12 December 2020

Matrix metalloproteinase-9 is up-regulated by CCL21/CCR7 interaction via extracellular signal-regulated kinase-1/2 signaling and is involved in CCL21-driven B-cell chronic lymphocytic leukemia cell invasion and migration

1 reference

12 December 2020

Homeostatic chemokines increase survival of B-chronic lymphocytic leukemia cells through inactivation of transcription factor FOXO3a

1 reference

12 December 2020

Identifiers

DOI

10.1186/1756-8722-6-89

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24305507%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

10 June 2020

0 references

1 reference

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10 June 2020

PubMed publication ID

24305507

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24305507%20AND%20SRC:MED&resulttype=core&format=json