IgG-paraoxonase-1 fusion protein for targeted drug delivery across the human blood-brain barrier (Q37408897)

20 August 2017

IgG-paraoxonase-1 fusion protein for targeted drug delivery across the human blood-brain barrier (English)

1 reference

20 August 2017

1 reference

1 reference

1 reference

20 August 2017

Ruben J Boado

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20 August 2017

Yun Zhang

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20 August 2017

Yufeng Zhang

series ordinal

1 reference

20 August 2017

Yuntao Wang

series ordinal

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20 August 2017

language of work or name

English

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publication date

1 November 2008

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20 August 2017

Molecular Pharmaceutics

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20 August 2017

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20 August 2017

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20 August 2017

1037-1043

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Re-engineering biopharmaceuticals for delivery to brain with molecular Trojan horses

20 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771892

Fusion antibody for Alzheimer's disease with bidirectional transport across the blood-brain barrier and abeta fibril disaggregation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771892

Stoichiometric and catalytic scavengers as protection against nerve agent toxicity: a mini review

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771892

Human paraoxonase: a promising approach for pre-treatment and therapy of organophosphorus poisoning.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771892

Sarin experiences in Japan: acute toxicity and long-term effects

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771892

Ciprofibrate increases paraoxonase activity in patients with metabolic syndrome

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771892

Human paraoxonases (PON1, PON2, and PON3) are lactonases with overlapping and distinct substrate specificities

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771892

Structure and evolution of the serum paraoxonase family of detoxifying and anti-atherosclerotic enzymes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771892

Pharmacogenetics of paraoxonases: a brief review

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771892

Biomaterials for mediation of chemical and biological warfare agents

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771892

Paraoxonase and atherosclerosis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771892

Genetic engineering, expression, and activity of a fusion protein of a human neurotrophin and a molecular Trojan horse for delivery across the human blood-brain barrier

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771892

Humanization of anti-human insulin receptor antibody for drug targeting across the human blood-brain barrier

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771892

Transport across the primate blood-brain barrier of a genetically engineered chimeric monoclonal antibody to the human insulin receptor

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771892

Genetic engineering of a lysosomal enzyme fusion protein for targeted delivery across the human blood-brain barrier

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771892

Butyrylcholinesterase, paraoxonase, and albumin esterase, but not carboxylesterase, are present in human plasma

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771892

High affinity, stability, and lactonase activity of serum paraoxonase PON1 anchored on HDL with ApoA-I.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771892

Protection by sustained release of physostigmine and procyclidine of soman poisoning in rats

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771892

Structure/function analyses of human serum paraoxonase (HuPON1) mutants designed from a DFPase-like homology model

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771892

A fluorogenic substrate for detection of organophosphatase activity

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771892

Early death due to severe organophosphate poisoning is a centrally mediated process.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771892

Paraoxonase and susceptibility to organophosphorus poisoning in farmers dipping sheep

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771892

The active site of human paraoxonase (PON1).

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2771892

A sandwich enzyme-linked immunosorbent assay for human serum paraoxonase concentration

2 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19434854

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Enzymatically Active Paraoxonase-1 Is Located at the External Membrane of Producing Cells and Released by a High Affinity, Saturable, Desorption Mechanism

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19434854

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cardiorespiratory effects produced by activation of cholinergic muscarinic receptors on the ventral surface of the medulla

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19434854

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/MP800113G

1 reference

20 August 2017

1 reference

20 August 2017

PubMed publication ID

19434854

1 reference