Structural and spatial determinants regulating TC21 activation by RasGRF family nucleotide exchange factors (Q37387979)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19692568%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

title

Structural and spatial determinants regulating TC21 activation by RasGRF family nucleotide exchange factors (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19692568%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19692568%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19692568%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Fernando Calvo

1 reference

20 August 2017

Piero Crespo

series ordinal

1 reference

20 August 2017

19 August 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19692568%20AND%20SRC:MED&resulttype=core&format=json

Molecular Biology of the Cell

5 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19692568%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

volume

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19692568%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19692568%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

page(s)

4289-4302

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19692568%20AND%20SRC:MED&resulttype=core&format=json

RasGRF2, a guanosine nucleotide exchange factor for Ras GTPases, participates in T-cell signaling responses

5 February 2020

cites work

1 reference

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6 September 2017

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H-Ras, R-Ras, and TC21 differentially regulate ureteric bud cell branching morphogenesis

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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The C-terminal end of R-Ras contains a focal adhesion targeting signal

6 September 2017

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Phospholipase Cgamma activates Ras on the Golgi apparatus by means of RasGRP1

6 September 2017

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A growing family of guanine nucleotide exchange factors is responsible for activation of ras-family GTPases

6 September 2017

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Guanine nucleotide exchange factors for Rho GTPases: turning on the switch

6 September 2017

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Involvement of phosphatidylinositol 3-kinase, but not RalGDS, in TC21/R-Ras2-mediated transformation

6 September 2017

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Activation of the Ral and phosphatidylinositol 3' kinase signaling pathways by the ras-related protein TC21.

6 September 2017

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Small GTP-binding proteins

6 September 2017

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Regulatory proteins of R-Ras, TC21/R-Ras2, and M-Ras/R-Ras3

6 September 2017

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Calmodulin-independent coordination of Ras and extracellular signal-regulated kinase activation by Ras-GRF2.

6 September 2017

1 reference

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R-Ras contains a proline-rich site that binds to SH3 domains and is required for integrin activation by R-Ras

6 September 2017

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Signal transduction elements of TC21, an oncogenic member of the R-Ras subfamily of GTP-binding proteins

6 September 2017

1 reference

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Endomembrane trafficking of ras: the CAAX motif targets proteins to the ER and Golgi

6 September 2017

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R-Ras signals through specific integrin alpha cytoplasmic domains to promote migration and invasion of breast epithelial cells

6 September 2017

1 reference

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Activation of the Raf/MAP kinase cascade by the Ras-related protein TC21 is required for the TC21-mediated transformation of NIH 3T3 cells

6 September 2017

1 reference

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Cholesterol-dependent retention of GPI-anchored proteins in endosomes

6 September 2017

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Role of the carboxyterminal residue in peptide binding to protein farnesyltransferase and protein geranylgeranyltransferase

6 September 2017

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6 September 2017

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Cloning and characterization of Ras-GRF2, a novel guanine nucleotide exchange factor for Ras

6 September 2017

1 reference

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The N-terminal pleckstrin, coiled-coil, and IQ domains of the exchange factor Ras-GRF act cooperatively to facilitate activation by calcium

6 September 2017

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Phosphorylation-dependent activation of the Ras-GRF/CDC25Mm exchange factor by muscarinic receptors and G-protein beta gamma subunits

6 September 2017

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The TC21 oncoprotein interacts with the Ral guanosine nucleotide dissociation factor.

6 September 2017

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A human oncogene of the RAS superfamily unmasked by expression cDNA cloning

6 September 2017

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Farnesyltransferase inhibitors are inhibitors of Ras but not R-Ras2/TC21, transformation

6 September 2017

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Differential response of the Ras exchange factor, Ras-GRF to tyrosine kinase and G protein mediated signals

6 September 2017

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Characterization of caveolin-rich membrane domains isolated from an endothelial-rich source: implications for human disease

6 September 2017

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A novel insertional mutation in the TC21 gene activates its transforming activity in a human leiomyosarcoma cell line.

6 September 2017

1 reference

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Characterization of four novel ras-like genes expressed in a human teratocarcinoma cell line

6 September 2017

1 reference

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Post-translational modifications of p21rho proteins

6 September 2017

1 reference

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Identification of differentially expressed genes in oral squamous cell carcinoma.

6 September 2017

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Exchange factors of the RasGRP family mediate Ras activation in the Golgi

14 September 2017

1 reference

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Distinct utilization of effectors and biological outcomes resulting from site-specific Ras activation: Ras functions in lipid rafts and Golgi complex are dispensable for proliferation and transformation

14 September 2017

1 reference

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Inhibitory effects of a dominant-interfering form of the Rho-GTPase Cdc42 in the chemoattractant-elicited signaling pathways leading to NADPH oxidase activation in differentiated HL-60 cells

28 September 2017

1 reference

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Prenylation of target GTPases contributes to signaling specificity of Ras-guanine nucleotide exchange factors

28 September 2017

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Calcium and calmodulin are essential for Ras-GRF1-mediated activation of the Ras pathway by lysophosphatidic acid

28 September 2017

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Myeloid leukemia cell growth and differentiation are independent of mitogen-activated protein kinase ERK1/2 activation.

28 September 2017

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The exchange factor Ras-GRF2 activates Ras-dependent and Rac-dependent mitogen-activated protein kinase pathways

28 September 2017

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Membrane association and targeting of prenylated Ras-like GTPases

28 September 2017

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Ras-GRF Activates Ha-Ras, but Not N-Ras or K-Ras 4B, Proteinin Vivo

28 September 2017

1 reference

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Mutational analysis of the properties of caveolin-1. A novel role for the C-terminal domain in mediating homo-typic caveolin-caveolin interactions

28 September 2017

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Overexpression of the Ras-related TC21/R-Ras2 protein may contribute to the development of human breast cancers

28 September 2017

1 reference

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Calcium activation of Ras mediated by neuronal exchange factor Ras-GRF.

28 September 2017

1 reference

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Geranylgeranylated, but not farnesylated, RhoB suppresses Ras transformation of NIH-3T3 cells

28 September 2017

1 reference

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Differences on the inhibitory specificities of H-Ras, K-Ras, and N-Ras (N17) dominant negative mutants are related to their membrane microlocalization

26 June 2018

1 reference

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Maintenance of CDC42 GDP-bound state by Rho-GDI inhibits MAP kinase activation by the exchange factor Ras-GRF. evidence for Ras-GRF function being inhibited by Cdc42-GDP but unaffected by CDC42-GTP.

26 June 2018

1 reference

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The Rho family GTPase Cdc42 regulates the activation of Ras/MAP kinase by the exchange factor Ras-GRF.

26 June 2018

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CDC25(Mm)/Ras-GRF1 regulates both Ras and Rac signaling pathways

26 June 2018

1 reference

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Ras-GRF, the activator of Ras, is expressed preferentially in mature neurons of the central nervous system.

26 June 2018

1 reference

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Activation of R-Ras by Ras-Guanine Nucleotide-releasing Factor

26 June 2018

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The brain specific Ras exchange factor CDC25 Mm: modulation of its activity through Gi-protein-mediated signals

26 June 2018

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C-terminal sequences in R-Ras are involved in integrin regulation and in plasma membrane microdomain distribution

26 June 2018

1 reference

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Hormonal regulation of phospholipase Cepsilon through distinct and overlapping pathways involving G12 and Ras family G-proteins

2 September 2018

1 reference

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Nonradioactive determination of Ras-GTP levels using activated ras interaction assay

2 September 2018

1 reference

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Biochemical studies of the mechanism of action of the Cdc42-GTPase-activating protein

2 September 2018

1 reference

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Bovine brain gray and white matter exhibit differential protein prenyl transferase activity

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2762140

The COOH-terminal end of R-Ras alters the motility and morphology of breast epithelial cells through Rho/Rho-kinase

2 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19692568

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

IPG (inositolphosphate glycan) as a cellular signal for TGF-β1 modulation of chondrocyte cell cycle

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19692568

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Activation of the exchange factor Ras-GRF by calcium requires an intact Dbl homology domain

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19692568

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1091/MBC.E09-03-0212

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19692568%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19692568%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

PubMed publication ID

19692568

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19692568%20AND%20SRC:MED&resulttype=core&format=json