A G-quadruplex stabilizer induces M-phase cell cycle arrest (Q37371599)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19531483%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

title

A G-quadruplex stabilizer induces M-phase cell cycle arrest (English)

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31 January 2020

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31 January 2020

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31 January 2020

Yuan-Chin Tsai

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31 January 2020

Haiyan Qi

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31 January 2020

Chao-Po Lin

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31 January 2020

Ren-Kuo Lin

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31 January 2020

John E Kerrigan

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31 January 2020

Suzanne G Rzuczek

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31 January 2020

Edmond J LaVoie

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31 January 2020

Joseph E Rice

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31 January 2020

Yi Lisa Lyu

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31 January 2020

language of work or name

English

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publication date

16 June 2009

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Journal of Biological Chemistry

31 January 2020

published in

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31 January 2020

volume

284

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31 January 2020

issue

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31 January 2020

page(s)

22535-22543

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The G-quartet containing FMRP binding site in FMR1 mRNA is a potent exonic splicing enhancer

31 January 2020

cites work

1 reference

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Ring-closing metathesis for the synthesis of a highly G-quadruplex selective macrocyclic hexaoxazole having enhanced cytotoxic potency

6 September 2017

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Lysinyl macrocyclic hexaoxazoles: synthesis and selective G-quadruplex stabilizing properties

6 September 2017

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Human telomere, oncogenic promoter and 5'-UTR G-quadruplexes: diverse higher order DNA and RNA targets for cancer therapeutics

6 September 2017

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Defining the mode, energetics and specificity with which a macrocyclic hexaoxazole binds to human telomeric G-quadruplex DNA

6 September 2017

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Telomere uncapping by the G-quadruplex ligand RHPS4 inhibits clonogenic tumour cell growth in vitro and in vivo consistent with a cancer stem cell targeting mechanism

6 September 2017

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An RNA G-quadruplex in the 5' UTR of the NRAS proto-oncogene modulates translation

6 September 2017

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Functional interaction of Aurora-A and PP2A during mitosis

6 September 2017

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Telomestatin-induced telomere uncapping is modulated by POT1 through G-overhang extension in HT1080 human tumor cells.

6 September 2017

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Epigenetic regulation of centromere formation and kinetochore function.

6 September 2017

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Histone variants--the structure behind the function

6 September 2017

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Cuts can kill: the roles of apoptotic nucleases in cell death and animal development

6 September 2017

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The effect of chemical modifications on the thermal stability of different G-quadruplex-forming oligonucleotides

6 September 2017

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Estrogen mediates Aurora-A overexpression, centrosome amplification, chromosomal instability, and breast cancer in female ACI rats

6 September 2017

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CENP-A phosphorylation by Aurora-A in prophase is required for enrichment of Aurora-B at inner centromeres and for kinetochore function

6 September 2017

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The cellular geography of aurora kinases

6 September 2017

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Retrotransposons provide an evolutionarily robust non-telomerase mechanism to maintain telomeres

6 September 2017

1 reference

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The serial cultivation of human diploid cell strains

6 September 2017

1 reference

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Function and regulation of Aurora/Ipl1p kinase family in cell division

6 September 2017

1 reference

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Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription

6 September 2017

1 reference

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Crystal structure of parallel quadruplexes from human telomeric DNA

6 September 2017

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A human nuclease specific for G4 DNA

6 September 2017

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In vitro generated antibodies specific for telomeric guanine-quadruplex DNA react with Stylonychia lemnae macronuclei

6 September 2017

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The Bloom's and Werner's syndrome proteins are DNA structure-specific helicases

6 September 2017

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Coexistence of alternative lengthening of telomeres and telomerase in hTERT-transfected GM847 cells

6 September 2017

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The length of telomeric G-rich strand 3'-overhang measured by oligonucleotide ligation assay

6 September 2017

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Tumor cell death induced by topoisomerase-targeting drugs.

6 September 2017

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The mitotic serine/threonine kinase Aurora2/AIK is regulated by phosphorylation and degradation

6 September 2017

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A critical role for telomeres in suppressing and facilitating carcinogenesis

6 September 2017

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Identification of a novel phosphorylation site on histone H3 coupled with mitotic chromosome condensation

6 September 2017

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p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2

6 September 2017

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The yeast telomere-binding protein RAP1 binds to and promotes the formation of DNA quadruplexes in telomeric DNA.

6 September 2017

1 reference

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Targeting human telomeric G-quadruplex DNA with oxazole-containing macrocyclic compounds.

6 September 2017

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Aurora A kinase RNAi and small molecule inhibition of Aurora kinases with VE-465 induce apoptotic death in multiple myeloma cells

14 September 2017

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G-quadruplexes induce apoptosis in tumor cells

14 September 2017

1 reference

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Role of apoptotic nuclease caspase-activated DNase in etoposide-induced treatment-related acute myelogenous leukemia

14 September 2017

1 reference

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Telomerase inhibition, telomere shortening, cell growth suppression and induction of apoptosis by telomestatin in childhood neuroblastoma cells

14 September 2017

1 reference

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Alternative lengthening of telomeres is characterized by high rates of telomeric exchange.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755660

The role of cdc25 in checkpoints and feedback controls in the eukaryotic cell cycle.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755660

A G-quadruplex-interactive potent small-molecule inhibitor of telomerase exhibiting in vitro and in vivo antitumor activity

14 September 2017

1 reference

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Altered cell cycle response of drug-resistant lung carcinoma cells to doxorubicin

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755660

The telomere lengthening mechanism in telomerase-negative immortal human cells does not involve the telomerase RNA subunit

28 September 2017

1 reference

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G-quadruplexes: the beginning and end of UTRs

28 September 2017

1 reference

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Telomeric RNA enters the game.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755660

Antitumor activity of G-quadruplex-interactive agent TMPyP4 in K562 leukemic cells.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755660

Synthesis and G-quadruplex stabilizing properties of a series of oxazole-containing macrocycles.

2 September 2018

1 reference

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The different biological effects of telomestatin and TMPyP4 can be attributed to their selectivity for interaction with intramolecular or intermolecular G-quadruplex structures.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755660

Telomestatin, a potent telomerase inhibitor that interacts quite specifically with the human telomeric intramolecular g-quadruplex

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2755660

Degradation of human Aurora-A protein kinase is mediated by hCdh1

2 September 2018

1 reference

12 December 2020

Verification of antiparallel G-quadruplex structure in human telomeres by using two-photon excitation fluorescence lifetime imaging microscopy of the 3,6-Bis(1-methyl-4-vinylpyridinium)carbazole diiodide molecule

1 reference

12 December 2020

Total synthesis of (R)-telomestatin

1 reference

12 December 2020

Telomerase inhibition with a novel G-quadruplex-interactive agent, telomestatin: in vitro and in vivo studies in acute leukemia

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M109.020230

1 reference

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31 January 2020

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31 January 2020

PubMed publication ID

19531483

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19531483%20AND%20SRC:MED&resulttype=core&format=json