Ciliary function and Wnt signal modulation (Q37369338)

20 August 2017

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title

Ciliary function and Wnt signal modulation (English)

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20 August 2017

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20 August 2017

Jantje M Gerdes

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20 August 2017

publication date

1 January 2008

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Current Topics in Developmental Biology

20 August 2017

published in

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20 August 2017

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20 August 2017

page(s)

175-195

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Enlarged ventricles in the cerebrum of loop-tail mice

20 August 2017

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7 January 2021

The roles of Groucho/Tle in left-right asymmetry and Kupffer's vesicle organogenesis.

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7 January 2021

Dishevelled activates JNK and discriminates between JNK pathways in planar polarity and wingless signaling

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7 January 2021

Primary cilia deletion in pancreatic epithelial cells results in cyst formation and pancreatitis

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7 January 2021

Orpk mouse model of polycystic kidney disease reveals essential role of primary cilia in pancreatic tissue organization

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7 January 2021

Planar cell polarity signalling couples cell division and morphogenesis during neurulation.

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7 January 2021

Wnt/beta-catenin signaling in development and disease

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7 January 2021

The genetic basis of mammalian neurulation.

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7 January 2021

Kif3a constrains beta-catenin-dependent Wnt signalling through dual ciliary and non-ciliary mechanisms

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7 January 2021

Vertebrate Smoothened functions at the primary cilium

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7 January 2021

Disruption of intraflagellar transport in adult mice leads to obesity and slow-onset cystic kidney disease

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7 January 2021

The emerging complexity of the vertebrate cilium: new functional roles for an ancient organelle

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7 January 2021

The Meckel-Gruber Syndrome proteins MKS1 and meckelin interact and are required for primary cilium formation

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7 January 2021

Phenotypic characterization of Bbs4 null mice reveals age-dependent penetrance and variable expressivity

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7 January 2021

Planar polarity from flies to vertebrates

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7 January 2021

Defective planar cell polarity in polycystic kidney disease

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7 January 2021

When cilia go bad: cilia defects and ciliopathies

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7 January 2021

Beta-catenin is essential for lamination but not neurogenesis in mouse retinal development

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7 January 2021

Disruption of the basal body compromises proteasomal function and perturbs intracellular Wnt response

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7 January 2021

The ciliary proteome database: an integrated community resource for the genetic and functional dissection of cilia

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7 January 2021

Planar cell polarity signalling controls cell division orientation during zebrafish gastrulation

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https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

Deciphering the function of canonical Wnt signals in development and disease: conditional loss- and gain-of-function mutations of beta-catenin in mice

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https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

Dishevelled and Wnt signaling: is the nucleus the final frontier?

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7 January 2021

Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene

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7 January 2021

Hedgehog signalling in the mouse requires intraflagellar transport proteins

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7 January 2021

Nuclear localization is required for Dishevelled function in Wnt/beta-catenin signaling

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7 January 2021

Analysis of kinesin-2 function in photoreceptor cells using synchronous Cre-loxP knockout of Kif3a with RHO-Cre.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

Ciliary proteins link basal body polarization to planar cell polarity regulation

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https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

JNK and ROKalpha function in the noncanonical Wnt/RhoA signaling pathway to regulate Xenopus convergent extension movements

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https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

Cystic kidney gene seahorse regulates cilia-mediated processes and Wnt pathways

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https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

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https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

The Wnt/Ca2+ pathway: a new vertebrate Wnt signaling pathway takes shape

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https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

The pck rat: a new model that resembles human autosomal dominant polycystic kidney and liver disease

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https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

The Oak Ridge Polycystic Kidney mouse: modeling ciliopathies of mice and men

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https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

Hypomorphic mutations in syndromic encephalocele genes are associated with Bardet-Biedl syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

Kidney-specific inactivation of the KIF3A subunit of kinesin-II inhibits renal ciliogenesis and produces polycystic kidney disease

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

The proteome of the mouse photoreceptor sensory cilium complex

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

The Wnt signaling pathway in development and disease

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https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

Dishevelled: a mobile scaffold catalyzing development

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

Mapping Wnt/beta-catenin signaling during mouse development and in colorectal tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

No tail co-operates with non-canonical Wnt signaling to regulate posterior body morphogenesis in zebrafish

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

Beta-catenin is necessary to keep cells of ureteric bud/Wolffian duct epithelium in a precursor state

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

Cilia orientation and the fluid mechanics of development

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

Situs inversus and embryonic ciliary morphogenesis defects in mouse mutants lacking the KIF3A subunit of kinesin-II

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

Optic cup and facial patterning defects in ocular ectoderm beta-catenin gain-of-function mice

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

Identification of Vangl2 and Scrb1 as planar polarity genes in mammals

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

Bardet-Biedl syndrome type 4 (BBS4)-null mice implicate Bbs4 in flagella formation but not global cilia assembly

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

Dishevelled proteins regulate cell adhesion in mouse blastocyst and serve to monitor changes in Wnt signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

Characterization of primary cilia and Hedgehog signaling during development of the human pancreas and in human pancreatic duct cancer cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

Bbs2-null mice have neurosensory deficits, a defect in social dominance, and retinopathy associated with mislocalization of rhodopsin

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

Inversin forms a complex with catenins and N-cadherin in polarized epithelial cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

The Invs gene encodes a microtubule-associated protein

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

Wnt signaling in disease and in development

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

Wnt signals mediate a fate decision between otic placode and epidermis

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

Regulation of primary cilia formation and left-right patterning in zebrafish by a noncanonical Wnt signaling mediator, duboraya

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determination

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

RhoA-mediated apical actin enrichment is required for ciliogenesis and promoted by Foxj1

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

Wnt/beta-catenin signaling regulates nephron induction during mouse kidney development

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

Ciliogenesis defects in embryos lacking inturned or fuzzy function are associated with failure of planar cell polarity and Hedgehog signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

Dishevelled controls apical docking and planar polarization of basal bodies in ciliated epithelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

Acute kidney injury and aberrant planar cell polarity induce cyst formation in mice lacking renal cilia.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

Patched1 regulates hedgehog signaling at the primary cilium

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

Early development of polycystic kidney disease in transgenic mice expressing an activated mutant of the beta-catenin gene

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

Loss of Fat4 disrupts PCP signaling and oriented cell division and leads to cystic kidney disease

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

PDGFRalphaalpha signaling is regulated through the primary cilium in fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

Frizzled/PCP signalling: a conserved mechanism regulating cell polarity and directed motility

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

The ins and outs of Wingless signaling.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

Dishevelled activates Ca2+ flux, PKC, and CamKII in vertebrate embryos.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

The duality of beta-catenin function: a requirement in lens morphogenesis and signaling suppression of lens fate in periocular ectoderm

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

The transmembrane protein meckelin (MKS3) is mutated in Meckel-Gruber syndrome and the wpk rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

Conserved patterns of cell movements during vertebrate gastrulation

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

Wnt-5a inhibits the canonical Wnt pathway by promoting GSK-3-independent beta-catenin degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

Inhibitory Gli3 activity negatively regulates Wnt/beta-catenin signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

A second canon. Functions and mechanisms of beta-catenin-independent Wnt signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

Zebrafish prickle, a modulator of noncanonical Wnt/Fz signaling, regulates gastrulation movements.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

The developmental biology of Dishevelled: an enigmatic protein governing cell fate and cell polarity

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

Neural tube closure requires Dishevelled-dependent convergent extension of the midline

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

Dishevelled genes mediate a conserved mammalian PCP pathway to regulate convergent extension during neurulation

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

The role of Frizzled3 and Frizzled6 in neural tube closure and in the planar polarity of inner-ear sensory hair cells

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

Dynamic association of proteasomal machinery with the centrosome

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

Early development of the brain and spinal cord in dysraphic mice: a transmission electron microscopic study

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

JNK functions in the non-canonical Wnt pathway to regulate convergent extension movements in vertebrates

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

Disruption of IFT results in both exocrine and endocrine abnormalities in the pancreas of Tg737(orpk) mutant mice

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2808%2900807-7

7 January 2021

10.1016/S0070-2153(08)00807-7

Identifiers

DOI

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20 August 2017

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