B-cell translocation gene 2 mediates crosstalk between PI3K/Akt1 and NFκB pathways which enhances transcription of MnSOD by accelerating IκBα degradation in normal and cancer cells. (Q37365789)

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scientific article published on 18 September 2013

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English	B-cell translocation gene 2 mediates crosstalk between PI3K/Akt1 and NFκB pathways which enhances transcription of MnSOD by accelerating IκBα degradation in normal and cancer cells.	scientific article published on 18 September 2013

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scholarly article

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22 February 2020

B-cell translocation gene 2 mediates crosstalk between PI3K/Akt1 and NFκB pathways which enhances transcription of MnSOD by accelerating IκBα degradation in normal and cancer cells (English)

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22 February 2020

3

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22 February 2020

author name string

Santhoshkumar Sundaramoorthy

1

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22 February 2020

Min Sook Ryu

2

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22 February 2020

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18 September 2013

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22 February 2020

Cell Communication and Signaling

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22 February 2020

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22 February 2020

69

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22 February 2020

Tis21 knock-out enhances the frequency of medulloblastoma in Patched1 heterozygous mice by inhibiting the Cxcl3-dependent migration of cerebellar neurons

1 reference

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6 September 2017

Mitochondria and cancer

1 reference

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6 September 2017

Cross-talk between NFkB and the PI3-kinase/AKT pathway can be targeted in primary effusion lymphoma (PEL) cell lines for efficient apoptosis.

1 reference

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6 September 2017

BTG2 suppresses cancer cell migration through inhibition of Src-FAK signaling by downregulation of reactive oxygen species generation in mitochondria

1 reference

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6 September 2017

Manganese superoxide dismutase regulation and cancer

1 reference

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6 September 2017

Metformin, an antidiabetic agent reduces growth of cutaneous squamous cell carcinoma by targeting mTOR signaling pathway

1 reference

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6 September 2017

B-cell translocation gene 2 (BTG2) stimulates cellular antioxidant defenses through the antioxidant transcription factor NFE2L2 in human mammary epithelial cells

1 reference

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6 September 2017

Various p53 mutant proteins differently regulate the Ras circuit to induce a cancer-related gene signature

1 reference

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6 September 2017

Manganese superoxide dismutase: guardian of the powerhouse

1 reference

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6 September 2017

Akt fine-tunes NF-κB-dependent gene expression during T cell activation

1 reference

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6 September 2017

Acetylation of MnSOD directs enzymatic activity responding to cellular nutrient status or oxidative stress.

1 reference

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6 September 2017

BTG/TOB factors impact deadenylases

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1 reference

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6 September 2017

The BTG2 protein is a general activator of mRNA deadenylation

1 reference

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6 September 2017

A systematic search for downstream mediators of tumor suppressor function of p53 reveals a major role of BTG2 in suppression of Ras-induced transformation

1 reference

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Phosphorylation of serine 147 of tis21/BTG2/pc3 by p-Erk1/2 induces Pin-1 binding in cytoplasm and cell death

1 reference

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6 September 2017

TIS21/BTG2/PC3 is expressed through PKC-delta pathway and inhibits binding of cyclin B1-Cdc2 and its activity, independent of p53 expression.

1 reference

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6 September 2017

On the Origin of Cancer Cells

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6 September 2017

Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress

1 reference

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6 September 2017

PC3 potentiates NGF-induced differentiation and protects neurons from apoptosis

1 reference

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6 September 2017

Transcriptional regulation of the human manganese superoxide dismutase gene: the role of specificity protein 1 (Sp1) and activating protein-2 (AP-2).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3851984

6 September 2017

Antiproliferative B cell translocation gene 2 protein is down-regulated post-transcriptionally as an early event in prostate carcinogenesis

1 reference

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6 September 2017

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1 reference

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6 September 2017

Nuclear factor kappaB-dependent mechanisms coordinate the synergistic effect of PMA and cytokines on the induction of superoxide dismutase 2

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Arrest of G(1)-S progression by the p53-inducible gene PC3 is Rb dependent and relies on the inhibition of cyclin D1 transcription

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An intronic NF-kappaB element is essential for induction of the human manganese superoxide dismutase gene by tumor necrosis factor-alpha and interleukin-1beta

1 reference

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Identification of BTG2, an antiproliferative p53-dependent component of the DNA damage cellular response pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3851984

6 September 2017

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1 reference

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Increased manganese superoxide dismutase expression suppresses the malignant phenotype of human melanoma cells

1 reference

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6 September 2017

Stimulation-dependent I kappa B alpha phosphorylation marks the NF-kappa B inhibitor for degradation via the ubiquitin-proteasome pathway

1 reference

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1 reference

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TIS21 negatively regulates hepatocarcinogenesis by disruption of cyclin B1-Forkhead box M1 regulation loop

1 reference

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Impaired expression of the cell cycle regulator BTG2 is common in clear cell renal cell carcinoma

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14 September 2017

DNA microarrays identification of primary and secondary target genes regulated by p53.

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28 September 2017

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B cell translocation gene 2 enhances susceptibility of HeLa cells to doxorubicin-induced oxidative damage

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26 June 2018

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p53 Regulates the Ras circuit to inhibit the expression of a cancer-related gene signature by various molecular pathways.

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1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/24047462

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based on heuristic

inferred from PubMed ID database lookup

Roles of nuclear factor-kappaB, p53, and p21/WAF1 in daunomycin-induced cell cycle arrest and apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/24047462

12 December 2020

based on heuristic

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Differential expression of TIS21 and TIS1 genes in the various organs of Balb/c mice, thymic carcinoma tissues and human cancer cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/24047462

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1186/1478-811X-11-69

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22 February 2020

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22 February 2020

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Europe PubMed Central

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22 February 2020

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