Contribution of organic cation transporter 2 (OCT2) to cisplatin-induced nephrotoxicity (Q37353430)

19 August 2017

Contribution of organic cation transporter 2 (OCT2) to cisplatin-induced nephrotoxicity (English)

1 reference

19 August 2017

K K Filipski

1 reference

19 August 2017

R H Mathijssen

1 reference

19 August 2017

T S Mikkelsen

1 reference

19 August 2017

A H Schinkel

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19 August 2017

A Sparreboom

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19 August 2017

language of work or name

English

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publication date

22 July 2009

1 reference

Clinical Pharmacology & Therapeutics

19 August 2017

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19 August 2017

1 reference

19 August 2017

1 reference

19 August 2017

396-402

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The copper transporter Ctr1 contributes to cisplatin uptake by renal tubular cells during cisplatin nephrotoxicity

19 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746866

Cisplatin nephrotoxicity: mechanisms and renoprotective strategies

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746866

Cisplatin nephrotoxicity: a review

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746866

Organic anion transporter 3 (Oat3/Slc22a8) knockout mice exhibit altered clearance and distribution of penicillin G

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746866

Polyspecific organic cation transporters: structure, function, physiological roles, and biopharmaceutical implications

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746866

Organic cation transporters are determinants of oxaliplatin cytotoxicity.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746866

Evaluation of an alternate dosing strategy for cisplatin in patients with extreme body surface area values

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746866

Cisplatin nephrotoxicity is critically mediated via the human organic cation transporter 2

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746866

Transport of drugs in the kidney by the human organic cation transporter, OCT2 and its genetic variants

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746866

Deficiency in the organic cation transporters 1 and 2 (Oct1/Oct2 [Slc22a1/Slc22a2]) in mice abolishes renal secretion of organic cations

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746866

Body-surface area-based dosing does not increase accuracy of predicting cisplatin exposure

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746866

Reduced hepatic uptake and intestinal excretion of organic cations in mice with a targeted disruption of the organic cation transporter 1 (Oct1 [Slc22a1]) gene

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746866

Review of the comparative pharmacology and clinical activity of cisplatin and carboplatin

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746866

Phase I/II study of a short course of weekly cisplatin in patients with advanced solid tumours

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746866

Nephrotoxicity of platinum complexes is related to basolateral organic cation transport

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746866

Functional characteristics and steroid hormone-mediated regulation of an organic cation transporter in Madin-Darby canine kidney cells.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746866

Renal toxicities of antineoplastic drugs and bone marrow transplantation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746866

Interaction of Cisplatin with the human organic cation transporter 2.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746866

Genetic variants of the organic cation transporter 2 influence the disposition of metformin

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746866

Impaired organic anion transport in kidney and choroid plexus of organic anion transporter 3 (Oat3 (Slc22a8)) knockout mice.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746866

2 September 2018

Cisplatin nephrotoxicity

1 reference

12 December 2020

Disposition and distribution of platinum following parenteral administration of cis-dichlorodiammineplatinum(II) to animals

1 reference

12 December 2020

Mechanisms of renal excretion of cisdichlorodiamine platinum

1 reference

12 December 2020

Cisplatin nephrotoxicity: insights into mechanism

1 reference

12 December 2020

Association of cisplatin nephrotoxicity with patient characteristics and cisplatin administration methods

1 reference

12 December 2020

Impact of Abcc2 (Mrp2) and Abcc3 (Mrp3) on the in vivo elimination of methotrexate and its main toxic metabolite 7-hydroxymethotrexate

1 reference

12 December 2020

Identifiers

DOI

10.1038/CLPT.2009.139

1 reference

19 August 2017

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19 August 2017

PubMed publication ID

19625999

1 reference