Biochemical determinants of tumor sensitivity to 5-fluorouracil: Ultrasensitive methods for the determination of 5-fluoro-2′-deoxyuridylate, 2′-deoxyuridylate, and thymidylate synthetase (Q37321552)

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scientific article published on March 1, 1979

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English	Biochemical determinants of tumor sensitivity to 5-fluorouracil: Ultrasensitive methods for the determination of 5-fluoro-2′-deoxyuridylate, 2′-deoxyuridylate, and thymidylate synthetase	scientific article published on March 1, 1979

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instance of

scholarly article

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Europe PubMed Central

PMC publication ID

383271

retrieved

19 August 2017

title

Biochemical determinants of tumor sensitivity to 5-fluorouracil: ultrasensitive methods for the determination of 5-fluoro-2'-deoxyuridylate, 2'-deoxyuridylate, and thymidylate synthetase (English)

2 references

stated in

Europe PubMed Central

PMC publication ID

383271

retrieved

19 August 2017

stated in

Europe PubMed Central

PubMed publication ID

108681

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A108681

retrieved

26 April 2022

Biochemical determinants of tumor sensitivity to 5-fluorouracil: Ultrasensitive methods for the determination of 5-fluoro-2′-deoxyuridylate, 2′-deoxyuridylate, and thymidylate synthetase (English)

1 reference

stated in

Crossref

DOI

10.1073/PNAS.76.3.1456

reference URL

https://api.crossref.org/works/10.1073/PNAS.76.3.1456

retrieved

25 November 2022

main subject

fluorouracil

1 reference

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inferred from title

author name string

R. G. Moran

series ordinal

1

1 reference

stated in

Europe PubMed Central

PubMed publication ID

108681

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A108681

retrieved

26 April 2022

C. P. Spears

series ordinal

2

1 reference

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Europe PubMed Central

PubMed publication ID

108681

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A108681

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26 April 2022

C. Heidelberger

series ordinal

3

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stated in

Europe PubMed Central

PubMed publication ID

108681

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A108681

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26 April 2022

language of work or name

English

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publication date

1 March 1979

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Europe PubMed Central

PMC publication ID

383271

retrieved

19 August 2017

full work available at URL

https://europepmc.org/articles/PMC383271

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HTML

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open access

content deliverer

Europe PubMed Central

1 reference

stated in

Europe PubMed Central

PubMed publication ID

108681

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A108681

retrieved

26 April 2022

https://europepmc.org/articles/PMC383271?pdf=render

file format

Portable Document Format

online access status

open access

content deliverer

Europe PubMed Central

1 reference

stated in

Europe PubMed Central

PubMed publication ID

108681

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A108681

retrieved

26 April 2022

https://pnas.org/doi/pdf/10.1073/pnas.76.3.1456

1 reference

stated in

Crossref

DOI

10.1073/PNAS.76.3.1456

reference URL

https://api.crossref.org/works/10.1073/PNAS.76.3.1456

retrieved

25 November 2022

published in

Proceedings of the National Academy of Sciences of the United States of America

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stated in

Europe PubMed Central

PMC publication ID

383271

retrieved

19 August 2017

volume

76

1 reference

stated in

Europe PubMed Central

PMC publication ID

383271

retrieved

19 August 2017

issue

3

1 reference

stated in

Europe PubMed Central

PMC publication ID

383271

retrieved

19 August 2017

page(s)

1456-1460

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stated in

Europe PubMed Central

PMC publication ID

383271

retrieved

19 August 2017

cites work

A generalized computer program for the treatment of data from competitive protein-binding assays including radioimmunoassays

1 reference

stated in

PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=383271

retrieved

6 September 2017

5-Fluoro-2′-Deoxyuridylate: Covalent Complex with Thymidylate Synthetase

1 reference

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PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=383271

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6 September 2017

Biochemical determinants of 5-fluorouracil response in vivo. The role of deoxyuridylate pool expansion

1 reference

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PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=383271

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6 September 2017

Quenching of thymidylate synthetase fluorescence by substrate analogs

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=383271

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14 September 2017

Effect of 5,10-methylenetetrahydrofolate on the dissociation of 5-fluoro-2'-deoxyuridylate from thymidylate synthetase: evidence for an ordered mechanism

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=383271

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14 September 2017

Chemotherapy of Gastrointestinal Cancer

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14 September 2017

The regulation of thymidylate biosynthesis in Novikoff hepatoma cells and the effects of amethopterin, 5-fluorodeoxyuridine, and 3-deazauridine

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14 September 2017

Purification of Thymidylate Synthetase from Ehrlich Ascites Carcinoma Cells

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26 June 2018

Crystalline Thymidylate Synthetase From Dichloromethotrexate Resistant Lactobacillus Case I

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26 June 2018

A filter assay for thymidylate synthetase using 5-fluoro-2'-deoxyuridylate as an active site titrant.

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PubMed Central

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26 June 2018

Thymidylate synthetase: mechanism of inhibition by 5-fluoro-2'-deoxyuridylate.

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PubMed Central

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26 June 2018

A rapid, radiochemical-ligand binding assay for methotrexate

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26 June 2018

Tumor 5-fluorodeoxyuridylate concentration as a determinant of 5-fluorouracil response

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26 June 2018

Effects of 5-fluorouracil on 5-fluorodeoxyuridine 5'-monophosphate and 2-deoxyuridine 5'-monophosphate pools, and DNA synthesis in solid mouse L1210 and rat Walker 256 tumors

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PubMed Central

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26 June 2018

A ten-year study of 5-flurouracil in disseminated breast cancer with clinical results and survival times

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2 September 2018

PURIFICATION AND PROPERTIES OF DIHYDROFOLATE REDUCTASE FROM EHRLICH ASCITES CARCINOMA CELLS

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Determination of protein: A modification of the lowry method that gives a linear photometric response

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/108681

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12 December 2020

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Assay of 5-fluorodeoxyuridine 5'-monophosphate deoxyuridine 5'-monophosphate pools following 5-fluorouracil

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/108681

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12 December 2020

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Methods for the separation and identification of ribonucleotides on DEAE-cellulose

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/108681

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12 December 2020

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Thymidylate synthetase from amethopterin- resistant Lactobacillus casei

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/108681

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12 December 2020

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inferred from PubMed ID database lookup

Folate metabolism in mammalian cells in culture. I Partial characterization of the folate derivatives present in L1210 mouse leukemia cells

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/108681

retrieved

12 December 2020

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Identifiers

DOI

10.1073/PNAS.76.3.1456

1 reference

stated in

Europe PubMed Central

PMC publication ID

383271

retrieved

19 August 2017

ADS bibcode

1979PNAS...76.1456M

0 references

PMC publication ID

383271

1 reference

stated in

Europe PubMed Central

PMC publication ID

383271

retrieved

19 August 2017

PubMed publication ID

108681

1 reference

stated in

Europe PubMed Central

PMC publication ID

383271

retrieved

19 August 2017

ResearchGate publication ID

23025638

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