Genetic susceptibility to eating disorders: associated polymorphisms and pharmacogenetic suggestions (Q37293990)

19 August 2017

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title

Genetic susceptibility to eating disorders: associated polymorphisms and pharmacogenetic suggestions (English)

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19 August 2017

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Mario Maj

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19 August 2017

Palmiero Monteleone

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19 August 2017

publication date

1 October 2008

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19 August 2017

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19 August 2017

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19 August 2017

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19 August 2017

page(s)

1487-1520

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The human genetics of anorexia nervosa

19 August 2017

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A psychobiological model of temperament and character

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Allelic Variation of Human Serotonin Transporter Gene Expression

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Serotonin transporter regulatory region polymorphism is associated with anorexia nervosa

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Serotonin transporter gene-linked polymorphic region: allele distributions in relationship to body weight and in anorexia nervosa

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21 January 2018

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Investigation of epistasis between the serotonin transporter and norepinephrine transporter genes in anorexia nervosa

21 January 2018

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Polymorphisms within the promoter and the intron 2 of the serotonin transporter gene in a population of bulimic patients

21 January 2018

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Investigation of the serotonin transporter regulatory region polymorphism in bulimia nervosa: relationships to harm avoidance, nutritional parameters, and psychiatric comorbidity

21 January 2018

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Association of a functional serotonin transporter gene polymorphism with binge eating disorder

21 January 2018

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The 5HTTLPR polymorphism, psychopathologic symptoms, and platelet [3H-] paroxetine binding in bulimic syndromes

21 January 2018

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Association of catecholamine-O-methyltransferase and 5-HTTLPR genotype with eating disorder-related behavior and attitudes in females with eating disorders.

21 January 2018

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Contribution of the serotoninergic system to anxious and depressive traits that may be partially responsible for the phenotypical variability of bulimia nervosa.

21 January 2018

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Epistatic interaction between the monoamine oxidase A and serotonin transporter genes in anorexia nervosa

21 January 2018

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Serotonergic dysfunction across the eating disorders: relationship to eating behaviour, purging behaviour, nutritional status and general psychopathology

21 January 2018

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Serotonergic control of the organization of feeding and satiety

21 January 2018

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The -1438A/G polymorphism in the 5-hydroxytryptamine type 2A receptor gene affects promoter activity

21 January 2018

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Serotonin-2A receptor gene polymorphisms are associated with serotonin-induced platelet aggregation

21 January 2018

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5-HT2A promoter polymorphism in anorexia nervosa

21 January 2018

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5-HT2A promoter polymorphism -1438G/A, anorexia nervosa, and obsessive-compulsive disorder

21 January 2018

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5-HT2A receptor gene polymorphism and eating disorders

21 January 2018

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Psychopathological traits and 5-HT2A receptor promoter polymorphism (-1438 G/A) in patients suffering from Anorexia Nervosa and Bulimia Nervosa

21 January 2018

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5-HT2A promoter polymorphism is not associated with anorexia nervosa in Japanese patients.

21 January 2018

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Association between 5HT2A receptor gene promoter region polymorphism and eating disorders in Japanese patients

21 January 2018

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5-HT(2A) gene promoter polymorphism as a modifying rather than a vulnerability factor in anorexia nervosa

21 January 2018

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Association of the promoter polymorphism -1438G/A of the 5-HT2A receptor gene with behavioral impulsiveness and serotonin function in women with bulimia nervosa

21 January 2018

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Analysis of the -1438 G/A polymorphism of the 5-HT2A serotonin receptor gene in bulimia nervosa patients with or without a history of anorexia nervosa

21 January 2018

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Association between a polymorphism of the 5-HT2C receptor and weight loss in teenage girls

21 January 2018

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Association of the 5-HT2c gene with susceptibility and minimum body mass index in anorexia nervosa

21 January 2018

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Further evidence of association of OPRD1 & HTR1D polymorphisms with susceptibility to anorexia nervosa

21 January 2018

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Polymorphism of the serotonin 5-HT1B receptor gene (HTR1B) associated with minimum lifetime body mass index in women with bulimia nervosa

21 January 2018

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The serotonin-1Dbeta receptor gene and severity of obsessive-compulsive disorder in women with bulimia nervosa.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

Human dopamine transporter gene (DAT1) maps to chromosome 5p15.3 and displays a VNTR.

21 January 2018

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The variable number of tandem repeats element in DAT1 regulates in vitro dopamine transporter density

21 January 2018

1 reference

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Dopamine transporter gene (DAT1) associated with appetite suppression to methylphenidate in a case-control study of binge eating disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

Association of multiple DRD2 polymorphisms with anorexia nervosa

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

A functional polymorphism in the promoter region of the dopamine D2 receptor gene is associated with schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

Functional analysis of the human D2 dopamine receptor missense variants

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

Synonymous mutations in the human dopamine receptor D2 (DRD2) affect mRNA stability and synthesis of the receptor

21 January 2018

1 reference

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The A1 allele of the human D2 dopamine receptor gene is associated with increased activity of striatal L-amino acid decarboxylase in healthy subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

Identification of a polymorphism in the promoter region of DRD4 associated with the human novelty seeking personality trait

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

Altered norepinephrine metabolism following long-term weight recovery in patients with anorexia nervosa

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

Anorexia nervosa (restrictive subtype) is associated with a polymorphism in the novel norepinephrine transporter gene promoter polymorphic region

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

The beta 3-adrenergic receptor gene Trp64Arg mutation is overrepresented in obese women. Effects on weight, BMI, abdominal fat, blood pressure, and reproductive history in an elderly Australian population

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

Association of ghrelin receptor gene polymorphism with bulimia nervosa in a Japanese population.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

Association of anorexia nervosa with the high activity allele of the COMT gene: a family-based study in Israeli patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

Combined family trio and case-control analysis of the COMT Val158Met polymorphism in European patients with anorexia nervosa

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

Haplotype analysis of the COMT-ARVCF gene region in Israeli anorexia nervosa family trios

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

A functional polymorphism in the monoamine oxidase A gene promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

Gene-gene interaction between the monoamine oxidase A gene and solute carrier family 6 (neurotransmitter transporter, noradrenalin) member 2 gene in anorexia nervosa (restrictive subtype)

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

Circulating brain-derived neurotrophic factor is decreased in women with anorexia and bulimia nervosa but not in women with binge-eating disorder: relationships to co-morbid depression, psychopathology and hormonal variables

21 January 2018

1 reference

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No change between the serum brain-derived neurotrophic factor in female patients with anorexia nervosa before and after partial weight recovery

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

Met66 in the brain-derived neurotrophic factor (BDNF) precursor is associated with anorexia nervosa restrictive type.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

Association of BDNF with anorexia, bulimia and age of onset of weight loss in six European populations

21 January 2018

1 reference

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Association of BDNF with restricting anorexia nervosa and minimum body mass index: a family-based association study of eight European populations

21 January 2018

1 reference

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Association between the brain-derived neurotrophic factor 196G/A polymorphism and eating disorders

21 January 2018

1 reference

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BDNF Met66 allele is associated with anorexia nervosa in the Polish population

21 January 2018

1 reference

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Mutation screen of the brain derived neurotrophic factor gene (BDNF): Identification of several genetic variants and association studies in patients with obesity, eating disorders, and attention-deficit/hyperactivity disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

Types of depression more frequent in bipolar than in unipolar affective illness: results of the Polish DEP-BI study.

21 January 2018

1 reference

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Family trios analysis of common polymorphisms in the obestatin/ghrelin, BDNF and AGRP genes in patients with Anorexia nervosa: association with subtype, body-mass index, severity and age of onset

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

The 196G/A (val66met) polymorphism of the BDNF gene is significantly associated with binge eating behavior in women with bulimia nervosa or binge eating disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

A DRD4/BDNF gene-gene interaction associated with maximum BMI in women with bulimia nervosa

21 January 2018

1 reference

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Contribution of NTRK2 to the genetic susceptibility to anorexia nervosa, harm avoidance and minimum body mass index

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

Association between an agouti-related protein gene polymorphism and anorexia nervosa

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

Phenotypes in three pedigrees with autosomal dominant obesity caused by haploinsufficiency mutations in the melanocortin-4 receptor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

RAPID COMMUNICATION: A Novel Melanocortin 4 Receptor (MC4R) Gene Mutation Associated with Morbid Obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

Binge eating as a major phenotype of melanocortin 4 receptor gene mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

Clinical spectrum of obesity and mutations in the melanocortin 4 receptor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

Binge-eating episodes are not characteristic of carriers of melanocortin-4 receptor gene mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

Melanocortin 4 receptor mutations in a large cohort of severely obese adults: prevalence, functional classification, genotype-phenotype relationship, and lack of association with binge eating

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

Functional analyses of melanocortin-4 receptor mutations identified from patients with binge eating disorder and nonobese or obese subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

Reduced cellular expression and activity of the P129T mutant of human fatty acid amide hydrolase: evidence for a link between defects in the endocannabinoid system and problem drug use.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

The cDNA 385C to A missense polymorphism of the endocannabinoid degrading enzyme fatty acid amide hydrolase (FAAH) is associated with overweight/obesity but not with binge eating disorder in overweight/obese women

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

Blood levels of the endocannabinoid anandamide are increased in anorexia nervosa and in binge-eating disorder, but not in bulimia nervosa

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

Neuroendocrine dysregulation of food intake in eating disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

Possible role of preproghrelin gene polymorphisms in susceptibility to bulimia nervosa.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

Single nucleotide polymorphisms in the leptin receptor gene: studies in anorexia nervosa.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

Increased uncoupling protein-2 and -3 mRNA expression during fasting in obese and lean humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

Analysis of microsatellite markers at the UCP2/UCP3 locus on chromosome 11q13 in anorexia nervosa

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

Uncoupling protein-2/uncoupling protein-3 gene polymorphism is not associated with anorexia nervosa.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

Analysis of tumor necrosis factor-alpha gene promoter polymorphisms in anorexia nervosa.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

TNF-α and intPLA2 genes' polymorphism in anorexia nervosa.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

Systematic mutation screening of the estrogen receptor beta gene in probands of different weight extremes: identification of several genetic variants

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

Isolation of a novel potassium channel gene hSKCa3 containing a polymorphic CAG repeat: a candidate for schizophrenia and bipolar disorder?

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

hKCa3/KCNN3 potassium channel gene: association of longer CAG repeats with schizophrenia in Israeli Ashkenazi Jews, expression in human tissues and localization to chromosome 1q21.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

CAG repeat polymorphism within the KCNN3 gene is a significant contributor to susceptibility to anorexia nervosa: a case-control study of female patients and several ethnic groups in the Israeli Jewish population.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

The 3111T/C polymorphism of the CLOCK gene confers a predisposition to a lifetime lower body weight in patients with anorexia nervosa and bulimia nervosa: a preliminary study

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

Pharmacologic treatment of eating disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

Fluoxetine after weight restoration in anorexia nervosa: a randomized controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

Serotonin transporter polymorphism and potential response to SSRIs in bulimia nervosa.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

Bulimia nervosa, 5-HTTLPR polymorphism and treatment response to four SSRIs: a single-blind study.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

The human serotonin transporter gene linked polymorphism (5-HTTLPR) shows ten novel allelic variants

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

Selection of eating-disorder phenotypes for linkage analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

The endophenotype concept in psychiatry: etymology and strategic intentions

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

Strategy for investigating interactions between measured genes and measured environments

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

5-HT2A receptor gene polymorphisms, anorexia nervosa, and obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

5-HT2A gene promoter polymorphism and anorexia nervosa

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

The 5-HT(2A) -1438G/A polymorphism in anorexia nervosa: a combined analysis of 316 trios from six European centres

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

No evidence for an involvement of alleles of polymorphisms in the serotonin1Dβ and 7 receptor genes in obesity, underweight or anorexia nervosa

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

β3-adrenergic-receptor allele distributions in children, adolescents and young adults with obesity, underweight or anorexia nervosa

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

Screening for mutations in the neuropeptide Y Y5 receptor gene in cohorts belonging to different weight extremes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

Case???control and combined family trios analysis of three polymorphisms in the ghrelin gene in European patients with anorexia and bulimia nervosa

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

No evidence for involvement of the leptin gene in anorexia nervosa, bulimia nervosa, underweight or early onset extreme obesity: identification of two novel mutations in the coding sequence and a novel polymorphism in the leptin gene linked upstream

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

Tryptophan hydroxylase and catechol-O-methyltransferase gene polymorphisms: relationships to monoamine metabolite concentrations in CSF of healthy volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

Binge Eating as a Phenotype of Melanocortin 4 Receptor Gene Mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

Association between 5-HT2A gene promoter polymorphism and anorexia nervosa

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

No association between a promoter polymorphism in the noradrenaline transporter gene and anorexia nervosa

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

5-HT2A receptor gene polymorphisms in anorexia nervosa and bulimia nervosa

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14622416.9.10.1487

10.2217/14622416.9.10.1487

21 January 2018

Identifiers

DOI

1 reference

19 August 2017

1 reference