Targeted inactivation of β1 integrin induces β3 integrin switching, which drives breast cancer metastasis by TGF-β (Q37270591)

19 August 2017

Targeted inactivation of β1 integrin induces β3 integrin switching, which drives breast cancer metastasis by TGF-β (English)

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19 August 2017

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Jenny G Parvani

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19 August 2017

Amy J Galliher-Beckley

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19 August 2017

Barbara J Schiemann

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19 August 2017

William P Schiemann

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19 August 2017

4 September 2013

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Molecular Biology of the Cell

19 August 2017

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19 August 2017

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19 August 2017

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19 August 2017

3449-3459

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describes a project that uses

19 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3814150/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Synergistic and multidimensional regulation of plasminogen activator inhibitor type 1 expression by transforming growth factor type β and epidermal growth factor

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β1-integrins signaling and mammary tumor progression in transgenic mouse models: implications for human breast cancer

6 September 2017

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Integrins in cell migration

6 September 2017

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Mechanisms by which the extracellular matrix and integrin signaling act to regulate the switch between tumor suppression and tumor promotion

6 September 2017

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The ins and outs of the epithelial to mesenchymal transition in health and disease

6 September 2017

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Down-regulation of epithelial cadherin is required to initiate metastatic outgrowth of breast cancer.

6 September 2017

1 reference

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Lysyl Oxidase Contributes to Mechanotransduction-Mediated Regulation of Transforming Growth Factor-β Signaling in Breast Cancer Cells

6 September 2017

1 reference

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Noncanonical TGF-β Signaling During Mammary Tumorigenesis

6 September 2017

1 reference

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Transforming growth factor-β and the hallmarks of cancer

6 September 2017

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Type II Transforming Growth Factor-β Receptor Recycling Is Dependent upon the Clathrin Adaptor Protein Dab2

6 September 2017

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TGF- Biology in Mammary Development and Breast Cancer

6 September 2017

1 reference

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beta1-integrin is dispensable for the induction of ErbB2 mammary tumors but plays a critical role in the metastatic phase of tumor progression

6 September 2017

1 reference

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Suppression of integrin alpha3beta1 in breast cancer cells reduces cyclooxygenase-2 gene expression and inhibits tumorigenesis, invasion, and cross-talk to endothelial cells

6 September 2017

1 reference

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Metastatic growth from dormant cells induced by a col-I-enriched fibrotic environment

6 September 2017

1 reference

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Epithelial-mesenchymal transition in cancer: parallels between normal development and tumor progression

6 September 2017

1 reference

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The pathophysiology of epithelial-mesenchymal transition induced by transforming growth factor-beta in normal and malignant mammary epithelial cells

6 September 2017

1 reference

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p130Cas is required for mammary tumor growth and transforming growth factor-beta-mediated metastasis through regulation of Smad2/3 activity.

6 September 2017

1 reference

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Therapeutic targeting of the focal adhesion complex prevents oncogenic TGF-beta signaling and metastasis

6 September 2017

1 reference

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Integrin beta1-focal adhesion kinase signaling directs the proliferation of metastatic cancer cells disseminated in the lungs

6 September 2017

1 reference

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EMT: when epithelial cells decide to become mesenchymal-like cells

6 September 2017

1 reference

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The role of vinculin in the regulation of the mechanical properties of cells

6 September 2017

1 reference

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A tense situation: forcing tumour progression

6 September 2017

1 reference

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Biomechanical regulation of cell orientation and fate

6 September 2017

1 reference

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Three-dimensional context regulation of metastasis

6 September 2017

1 reference

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Inhibition of metastatic outgrowth from single dormant tumor cells by targeting the cytoskeleton.

6 September 2017

1 reference

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The Foxc2 transcription factor regulates angiogenesis via induction of integrin beta3 expression

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814150

Grb2 binding to Tyr284 in TbetaR-II is essential for mammary tumor growth and metastasis stimulated by TGF-beta

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814150

Identification of a HoxA10 activation domain necessary for transcription of the gene encoding beta3 integrin during myeloid differentiation

6 September 2017

1 reference

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Beta3 integrin and Src facilitate transforming growth factor-beta mediated induction of epithelial-mesenchymal transition in mammary epithelial cells

6 September 2017

1 reference

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Tensional homeostasis and the malignant phenotype

6 September 2017

1 reference

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In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells

6 September 2017

1 reference

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New functions for the matrix metalloproteinases in cancer progression

6 September 2017

1 reference

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FAK integrates growth-factor and integrin signals to promote cell migration

6 September 2017

1 reference

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The dual role of cytoskeletal anchor proteins in cell adhesion and signal transduction

6 September 2017

1 reference

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Trans-dominant inhibition of integrin function.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814150

TGF-beta induced transdifferentiation of mammary epithelial cells to mesenchymal cells: involvement of type I receptors

6 September 2017

1 reference

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Structure and Biological Role of Vitronectin

6 September 2017

1 reference

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Plasminogen activator inhibitors regulate cell adhesion through a uPAR-dependent mechanism

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814150

Transforming growth factor beta1 induces alphavbeta3 integrin expression in human lung fibroblasts via a beta3 integrin-, c-Src-, and p38 MAPK-dependent pathway

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814150

Tumor cell invasiveness correlates with changes in integrin expression and localization

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814150

Integrin beta 1 signaling is necessary for transforming growth factor-beta activation of p38MAPK and epithelial plasticity

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3814150

Src phosphorylates Tyr284 in TGF-beta type II receptor and regulates TGF-beta stimulation of p38 MAPK during breast cancer cell proliferation and invasion

3 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24006485

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1091/MBC.E12-10-0776

1 reference

19 August 2017

1 reference

19 August 2017

PubMed publication ID

24006485

1 reference