Crohn's disease--defect in innate defence. (Q37276947)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18810765%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

review article

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title

Crohn's disease--defect in innate defence (English)

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14 January 2020

0 references

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14 January 2020

Michael Gersemann

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14 January 2020

Klaus Fellermann

series ordinal

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14 January 2020

Eduard Friedrich Stange

series ordinal

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14 January 2020

language of work or name

English

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publication date

1 September 2008

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World Journal of Gastroenterology

14 January 2020

published in

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14 January 2020

volume

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14 January 2020

issue

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14 January 2020

page(s)

5499-5503

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Impaired luminal processing of human defensin-5 in Crohn's disease: persistence in a complex with chymotrypsinogen and trypsin

14 January 2020

cites work

1 reference

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Microbial influences in inflammatory bowel diseases

6 September 2017

1 reference

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Identification of stem cells in small intestine and colon by marker gene Lgr5

6 September 2017

1 reference

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Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases

6 September 2017

1 reference

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Defensins and other antimicrobial peptides in inflammatory bowel disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746334

Reduced mucosal antimicrobial activity in Crohn's disease of the colon

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746334

Attenuated induction of epithelial and leukocyte serine antiproteases elafin and secretory leukocyte protease inhibitor in Crohn's disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746334

The role of microbes in Crohn's disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746334

Notch signaling in gastrointestinal tract (review).

6 September 2017

1 reference

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A chromosome 8 gene-cluster polymorphism with low human beta-defensin 2 gene copy number predisposes to Crohn disease of the colon

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746334

The bacteriology of biopsies differs between newly diagnosed, untreated, Crohn's disease and ulcerative colitis patients

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746334

Organizing cell renewal in the intestine: stem cells, signals and combinatorial control

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746334

Reduced Paneth cell alpha-defensins in ileal Crohn's disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746334

Wnt signalling induces maturation of Paneth cells in intestinal crypts

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746334

Defensin deficiency, intestinal microbes, and the clinical phenotypes of Crohn's disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746334

Defensin-mediated innate immunity in the small intestine

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746334

Defensins: antimicrobial peptides of innate immunity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746334

Extensive normal copy number variation of a beta-defensin antimicrobial-gene cluster

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746334

Crohn's disease and the NOD2 gene: a role for paneth cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746334

Inflammatory Bowel Disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746334

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746334

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746334

Stem cells: the intestinal stem cell as a paradigm.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746334

Psoriasis is associated with increased beta-defensin genomic copy number

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746334

NOD2 (CARD15) mutations in Crohn's disease are associated with diminished mucosal alpha-defensin expression

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746334

Innate immunity and colonic inflammation: enhanced expression of epithelial alpha-defensins

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746334

Expression and regulation of the human beta-defensins hBD-1 and hBD-2 in intestinal epithelium.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746334

Reduced alpha-defensin expression is associated with inflammation and not NOD2 mutation status in ileal Crohn's disease.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746334

Tracking down the stem cells of the intestine: strategies to identify adult stem cells

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746334

Heterogeneous expression of human cathelicidin hCAP18/LL-37 in inflammatory bowel diseases

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746334

Inducible and constitutive beta-defensins are differentially expressed in Crohn's disease and ulcerative colitis.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746334

Mucosal flora in inflammatory bowel disease

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2746334

Human beta-defensin 2 but not beta-defensin 1 is expressed preferentially in colonic mucosa of inflammatory bowel disease

3 September 2018

1 reference

12 December 2020

Increased expression of antimicrobial peptides and lysozyme in colonic epithelial cells of patients with ulcerative colitis

1 reference

12 December 2020

Effect of faecal stream diversion on recurrence of Crohn's disease in the neoterminal ileum

1 reference

12 December 2020

Presence of adherent Escherichia coli strains in ileal mucosa of patients with Crohn's disease

1 reference

12 December 2020

Intestinal stem cells

1 reference

12 December 2020

The Paneth cell alpha-defensin deficiency of ileal Crohn's disease is linked to Wnt/Tcf-4

1 reference

12 December 2020

Identifiers

DOI

10.3748/WJG.14.5499

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18810765%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18810765%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

PubMed publication ID

18810765

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18810765%20AND%20SRC:MED&resulttype=core&format=json