Spliceosomal proteomics in Trypanosoma brucei reveal new RNA splicing factors (Q37256235)

19 August 2017

Spliceosomal proteomics in Trypanosoma brucei reveal new RNA splicing factors (English)

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Small nuclear ribonucleoprotein-associated protein B (snRNP-B) (Sm protein B) (Sm-B) (SmB), putative

19 August 2017

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PRP19-like protein, putative

5 February 2019

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U1 snRNP-specific protein

5 February 2019

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small nuclear ribonucleoprotein sm d3

5 February 2019

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5 February 2019

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pre-mRNA splicing factor, putative

5 February 2019

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5 February 2019

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U6 snRNA-associated Sm-like protein LSm7p

5 February 2019

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small nuclear ribonucleoprotein Sm-E

5 February 2019

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small nuclear ribonucleoprotein, putative

5 February 2019

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5 February 2019

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small nuclear ribonucleoprotein SmD1

6 February 2019

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6 February 2019

ssm4 protein, putative

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spliceosomal U5 snRNP-specific protein, putative

6 February 2019

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u1 small nuclear ribonucleoprotein 70 kDa

6 February 2019

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U6 snRNA-associated sm-like protein Lsm2

6 February 2019

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U5Cwc21 small nuclear ribonucleoprotein

6 February 2019

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small nuclear ribonucleoprotein Sm-F

6 February 2019

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6 February 2019

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U4/U6-specific protein PRP4

6 February 2019

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6 February 2019

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U2 small nuclear ribonucleoprotein 16.5K

6 February 2019

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6 February 2019

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6 February 2019

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Splicing factor CRN, putative

6 February 2019

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U5 snRNP-specific 40 kDa protein

6 February 2019

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U6 snRNA-associated Sm-like protein LSm4p

6 February 2019

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small nuclear ribonucleoprotein Sm-G

6 February 2019

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U5 snRNP-associated 102 kDa protein, putative

6 February 2019

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author name string

Daniela Luz Ambrósio

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19 August 2017

Ju Huck Lee

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19 August 2017

Aswini K Panigrahi

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19 August 2017

Tu Ngoc Nguyen

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19 August 2017

Regina Maria Barretto Cicarelli

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19 August 2017

Arthur Günzl

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19 August 2017

8 May 2009

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19 August 2017

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19 August 2017

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19 August 2017

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19 August 2017

990-1000

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Transcriptionally active TFIIH of the early-diverged eukaryote Trypanosoma brucei harbors two novel core subunits but not a cyclin-activating kinase complex

19 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708463

The spliceosome: design principles of a dynamic RNP machine

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708463

Multifunctional class I transcription in Trypanosoma brucei depends on a novel protein complex

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708463

Active RNA polymerase I of Trypanosoma brucei harbors a novel subunit essential for transcription

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708463

Sm core variation in spliceosomal small nuclear ribonucleoproteins from Trypanosoma brucei

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708463

Purification of an eight subunit RNA polymerase I complex in Trypanosoma brucei

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708463

RNA-binding domain proteins in Kinetoplastids: a comparative analysis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708463

Highly efficient tandem affinity purification of trypanosome protein complexes based on a novel epitope combination

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708463

The genome of the kinetoplastid parasite, Leishmania major

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708463

U1 small nuclear RNP from Trypanosoma brucei: a minimal U1 snRNA with unusual protein components

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708463

trans and cis splicing in trypanosomatids: mechanism, factors, and regulation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708463

Nuclear speckles: a model for nuclear organelles

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708463

Pre-mRNA splicing: awash in a sea of proteins

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708463

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708463

Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708463

Arrangement of RNA and proteins in the spliceosomal U1 small nuclear ribonucleoprotein particle

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708463

Determinants for cap trimethylation of the U2 small nuclear RNA are not conserved between Trypanosoma brucei and higher eukaryotic organisms

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708463

Genetic interference in Trypanosoma brucei by heritable and inducible double-stranded RNA.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708463

The spliceosomal snRNP core complex of Trypanosoma brucei: cloning and functional analysis reveals seven Sm protein constituents

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708463

A new twist in trypanosome RNA metabolism: cis-splicing of pre-mRNA.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708463

In vitro analysis of alpha-amanitin-resistant transcription from the rRNA, procyclic acidic repetitive protein, and variant surface glycoprotein gene promoters in Trypanosoma brucei

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708463

A tightly regulated inducible expression system for conditional gene knock-outs and dominant-negative genetics in Trypanosoma brucei

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708463

Mechanical devices of the spliceosome: motors, clocks, springs, and things

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708463

A new cyclophilin and the human homologues of yeast Prp3 and Prp4 form a complex associated with U4/U6 snRNPs

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708463

The U5 RNA of trypanosomes deviates from the canonical U5 RNA: The Leptomonas collosoma U5 RNA and its coding gene

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708463

The trans-spliceosomal U2 snRNP protein 40K of Trypanosoma brucei: cloning and analysis of functional domains reveals homology to a mammalian snRNP protein

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708463

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708463

Affinity purification of Trypanosoma brucei small nuclear ribonucleoproteins reveals common and specific protein components

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708463

Analysis of small nuclear ribonucleoproteins (RNPs) in Trypanosoma brucei: structural organization and protein components of the spliced leader RNP

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708463

A comprehensive analysis of Trypanosoma brucei mitochondrial proteome

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708463

Identification of novel snRNA-specific Sm proteins that bind selectively to U2 and U4 snRNAs in Trypanosoma brucei

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708463

Trans mRNA splicing in trypanosomes: cloning and analysis of a PRP8-homologous gene from Trypanosoma brucei provides evidence for a U5-analogous RNP

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708463

Immunological characterization and intracellular localization of trans-spliceosomal small nuclear ribonucleoproteins in Trypanosoma brucei

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708463

Identification and functional characterization of lsm proteins in Trypanosoma brucei

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708463

Small nuclear ribonucleoprotein remodeling during catalytic activation of the spliceosome

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708463

Import of proteins into the trypanosome nucleus and their distribution at karyokinesis

3 September 2018

1 reference

12 December 2020

Cloning and recombinant expression of the La RNA-binding protein from Trypanosoma brucei

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12 December 2020

Biochemical and functional characterization of the cis-spliceosomal U1 small nuclear RNP from Trypanosoma brucei

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12 December 2020

New components of the spliced leader RNP required for nematode trans-splicing

1 reference

12 December 2020

Analysis of spliceosomal complexes in Trypanosoma brucei and silencing of two splicing factors Prp31 and Prp43

1 reference

12 December 2020

Identification of the heptameric Lsm complex that binds U6 snRNA in Trypanosoma brucei

1 reference

12 December 2020

U small nuclear ribonucleoprotein requirements for nematode cis- and trans-splicing in vitro

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12 December 2020

Identifiers

DOI

10.1128/EC.00075-09

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19 August 2017

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19 August 2017

PubMed publication ID

19429779

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